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Centessa Pharmaceuticals plc American (CNTA) Financials

CNTA NASDAQ
FY2025 annual
Revenue $15.0M n/m YoY
Net Income -$197.5M n/m YoY
EPS (Diluted) -$1.46 n/m YoY
Free Cash Flow -$194.2M n/m YoY
Source SEC Filings (10-K/10-Q) Latest period Q1 FY2026, ended Mar 31, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q1 FY2026, filed May 5, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the CNTA SEC filings page.

Centessa Pharmaceuticals plc American (CNTA) reported $15.0M in revenue for fiscal year 2025. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 7 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI CNTA FY2025

Centessa is still a research-led development business: revenue is emerging, but R&D spending and cash outflows remain far larger than revenue.

In FY2025, operating cash flow of -$193.8M nearly matched the net loss of $197.5M, while free cash flow was -$194.2M; this close agreement indicates that reported losses are translating into cash consumption rather than arising mainly from non-cash charges.

R&D was $172M, and its reported share of revenue was 1148.2%; the company therefore remains structurally development-led rather than commercially self-funding. From FY2023 to FY2025, revenue increased 118.9% while R&D increased 38.4%, showing that commercialization is advancing without yet absorbing the research platform's cost.

The balance sheet is equity-funded: debt-to-equity was 0.2x and liabilities represented 23.4% of assets, limiting the role of borrowing in financing the operation. The supplied liquidity measure equaled 35.7 months of the latest reported annual operating outflow, while the current ratio was 8.6x; together, these describe substantial short-term asset coverage alongside continuing losses.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 65 / 100
Financial Health Score 65/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group, and the overall is the average of the dimensions that can be computed. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Centessa Pharmaceuticals plc American's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
63

Centessa Pharmaceuticals plc American held $577.1M in cash, cash equivalents and investments at the end of fiscal year 2025, and its operations used $193.8M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and Centessa Pharmaceuticals plc American scores 63/100 among other emerging companies.

Dilution
31

Centessa Pharmaceuticals plc American had 155M shares outstanding at the end of fiscal year 2025, against 133M in fiscal year 2024. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and Centessa Pharmaceuticals plc American scores 31/100 among other emerging companies.

R&D Intensity
94

Centessa Pharmaceuticals plc American spent $172.2M on research and development in fiscal year 2025, which was 77.3% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and Centessa Pharmaceuticals plc American scores 94/100 among other emerging companies.

Revenue Progress
78

Centessa Pharmaceuticals plc American reported revenue of $15.0M in fiscal year 2025, against none in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and Centessa Pharmaceuticals plc American scores 78/100 among other emerging companies.

Burn Trend
38

Centessa Pharmaceuticals plc American's operations used $193.8M of cash in fiscal year 2025, against $142.1M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and Centessa Pharmaceuticals plc American scores 38/100 among other emerging companies.

Balance Sheet
85

Centessa Pharmaceuticals plc American's cash, cash equivalents and investments came to $577.1M at the end of fiscal year 2025, against $160.6M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and Centessa Pharmaceuticals plc American scores 85/100 among other emerging companies.

Piotroski F-Score Partial
4/8

Centessa Pharmaceuticals plc American passes 4 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, the one computable operating efficiency signal (asset turnover improving) passes.

Earnings Quality No Cash Backing
N/A

Centessa Pharmaceuticals plc American reported a net loss of $197.5M while operations used $193.8M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Centessa Pharmaceuticals plc American reported an operating loss of $207.7M against $11.5M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$0
YoY-100.0%

Centessa Pharmaceuticals plc American generated $0 in revenue in Q1 2026. This represents a decrease of 100.0% from the same quarter a year earlier.

EBITDA
-$79.5M
YoYn/m

Centessa Pharmaceuticals plc American's EBITDA was -$79.5M in Q1 2026, measuring earnings before interest, taxes, depreciation, and amortization. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative.

Net Income
-$79.2M
YoYn/m

Centessa Pharmaceuticals plc American reported a net loss of $79.2M in Q1 2026. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative.

EPS (Diluted)
-$0.52
YoYn/m
QoQn/m

Centessa Pharmaceuticals plc American earned -$0.52 per diluted share (EPS) in Q1 2026. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

Cash & Balance Sheet

Cash & Debt
$62.4M
YoY-40.6%
QoQ+1.8%
5Y CAGR-26.9%

Centessa Pharmaceuticals plc American held $62.4M in cash against $110.4M in long-term debt as of Q1 2026.

Shares Outstanding
155M
YoY+15.8%
QoQ+0.1%

Centessa Pharmaceuticals plc American had 155M shares outstanding in Q1 2026. This represents an increase of 15.8% from the same quarter a year earlier. Against the prior quarter it is up 0.1%.

Free Cash Flow

Not reported for Q1 2026.

Dividends Per Share

Not reported for Q1 2026.

Margins & Returns

Return on Equity
-16.3%
YoY-9.5pp

Centessa Pharmaceuticals plc American's quarterly ROE was -16.3% in Q1 2026: one quarter's net income over shareholder equity, not annualized. This is down 9.5 percentage points from the same quarter a year earlier.

Gross Margin

Not reported for Q1 2026.

Operating Margin

Not reported for Q1 2026.

Net Margin

Not reported for Q1 2026.

Capital Allocation

R&D Spending
$59.9M
YoY+79.1%

Centessa Pharmaceuticals plc American invested $59.9M in research and development in Q1 2026. This represents an increase of 79.1% from the same quarter a year earlier.

Share Buybacks

Not reported for Q1 2026.

Capital Expenditures

Not reported for Q1 2026.

CNTA Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CNTA quarterly income statement
MetricQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-QQ2'2410-Q
Revenue$0-100.0%N/A$0n/m$0n/m$15.0Mn/mN/A$0$0
R&D Expenses$59.9M+79.1%N/A$41.6M+22.6%$42.7M+30.2%$33.4M+47.6%N/A$33.9M+20.3%$32.8M-2.5%
SG&A Expenses$19.9M+61.2%N/A$12.2M-2.2%$11.9M+6.7%$12.3M-8.2%N/A$12.5M+4.0%$11.2M-16.3%
Operating Income-$79.8Mn/mN/A-$53.8Mn/m-$54.7Mn/m-$30.8Mn/mN/A-$46.4Mn/m-$44.0Mn/m
EBITDA-$79.5Mn/mN/A-$53.6Mn/m-$54.4Mn/m-$30.6Mn/mN/A-$46.2Mn/m-$43.7Mn/m
Interest Expense$2.7M-5.1%N/A$2.9M+13.0%$2.9M+14.2%$2.9M+13.8%N/A$2.6M+0.6%$2.5M+3.1%
Income Tax$850K-39.2%N/A$166K-72.7%$778K+10.4%$1.4M+190.4%N/A$608Kn/m$705Kn/m
Net Income-$79.2Mn/mN/A-$54.9Mn/m-$50.3Mn/m-$26.1Mn/mN/A-$42.6Mn/m-$43.8Mn/m
EPS (Basic)-$0.52n/m-$0.48n/m-$0.41n/m-$0.38n/m-$0.20n/m-$0.91n/m-$0.37n/m-$0.40n/m
EPS (Diluted)-$0.52n/m-$0.48n/m-$0.41n/m-$0.38n/m-$0.20n/m-$0.91n/m-$0.37n/m-$0.40n/m
Diluted Shares (Avg)154M+15.4%N/A134M+15.4%134M+22.1%133M+33.2%N/A116M+20.3%109M+15.1%

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

CNTA Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CNTA quarterly balance sheet
MetricQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-QQ2'2410-Q
Total Assets$641.8M+21.6%$687.5M+19.2%$448.3M-26.5%$492.1M+23.4%$527.8M+60.8%$576.8M+60.1%$609.7M+61.6%$398.8M+1.5%
Current Assets$348.7M+0.3%$367.9M-31.4%$307.7M-45.9%$300.4M-15.5%$347.7M+22.2%$536.4M+70.2%$568.4M+71.0%$355.5M+1.5%
Cash & Equivalents$62.4M-40.6%$61.3M-84.0%$50.8M-87.1%$44.2M-65.3%$105.2M-11.0%$383.2M+199.3%$395.0M+130.3%$127.4M-12.3%
Short-Term Investments$214.2M+19.4%$233.3M+135.7%$195.4M+58.3%$206.5M+23.3%$179.3M+60.2%$99.0M-23.0%$123.4M+12.4%$167.5M+5.7%
Long-Term Investments$257.1M+83.1%$282.5Mn/m$102.8Mn/m$153.4Mn/m$140.4Mn/m$0n/m$0n/m$0n/m
Total Liabilities$154.4M+9.1%$160.6M-8.3%$146.7M+32.7%$147.2M+31.6%$141.6M+25.3%$175.3M+41.3%$110.6M-6.3%$111.9M-3.8%
Current Liabilities$36.6M+51.1%$42.9M-26.0%$29.1M+10.3%$29.7M+11.0%$24.2M-11.8%$58.0M+47.3%$26.4M-24.5%$26.8M-21.0%
Non-Current Liabilities$117.8M+0.4%$117.7M+0.4%$117.6M+39.7%$117.5M+38.0%$117.4M+37.2%$117.3M+38.6%$84.2M+1.4%$85.1M+3.2%
Long-Term Debt$110.4M+1.1%$110.1M+1.1%$109.8M+45.1%$109.5M+43.2%$109.3M+42.3%$108.9M+43.9%$75.7M+2.3%$76.5M+4.4%
Total Equity$487.3M+26.2%$526.9M+31.2%$301.6M-39.6%$344.9M+20.2%$386.2M+79.5%$401.5M+70.0%$499.1M+92.4%$287.0M+3.7%
Retained Earnings-$1.3Bn/m-$1.2Bn/m-$1.1Bn/m-$1.1Bn/m-$1.0Bn/m-$988.7Mn/m-$877.4Mn/m-$834.8Mn/m

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill.

CNTA Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CNTA quarterly cash flow statement
MetricQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-QQ2'2410-Q
Operating Cash Flow-$72.2Mn/m-$55.8Mn/m-$58.3Mn/m-$22.5Mn/m-$57.2Mn/m-$42.8Mn/m-$21.4Mn/m-$40.6Mn/m
Depreciation & Amortization$239K+10.1%$241K+4.8%$237K+0.4%$226K-4.2%$217K-9.6%$230K-6.5%$236K-0.8%$236K-0.4%
Stock-Based Compensation$10.6M+34.0%N/A$7.2M-14.9%$7.9M-7.7%$7.9M-3.3%N/A$8.5M+11.8%$8.6M+19.4%
Capital ExpendituresN/A$11Kn/m$234K+588.2%N/AN/A$0-100.0%$34K-20.9%$0-100.0%
Free Cash FlowN/A-$55.8Mn/m-$58.5Mn/mN/AN/A-$42.8Mn/m-$21.4Mn/m-$40.6Mn/m
Investing Cash Flow$42.7Mn/m-$218.1M-972.5%$61.9M+37.8%-$40.0Mn/m-$222.4M-1426.7%$25.0Mn/m$45.0M-7.7%-$55.5Mn/m
Financing Cash Flow$30.5M+887.3%$283.4M+9464.6%$3.4M-98.6%$1.6M-98.5%$3.1M-70.6%$3.0M-53.4%$246.0M+1568.4%$105.3M+877508.3%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

CNTA Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CNTA quarterly financial ratios
MetricQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-QQ2'2410-Q
Operating MarginN/AN/AN/AN/A-205.2%N/AN/AN/A
Net MarginN/AN/AN/AN/A-174.2%N/AN/AN/A
Return on Equity-16.3%-9.5ppN/A-18.2%-9.7pp-14.6%+0.7pp-6.8%+10.9ppN/A-8.5%+6.4pp-15.3%-6.3pp
Return on Assets-12.3%-7.4ppN/A-12.2%-5.3pp-10.2%+0.8pp-5.0%+6.6ppN/A-7.0%+3.3pp-11.0%-4.7pp
Current Ratio9.53-4.8x8.57-0.7x10.56-11.0x10.12-3.2x14.37+4.0x9.25+1.2x21.52+12.0x13.29+2.9x
Debt-to-Equity0.23-0.1x0.21-0.1x0.36+0.2x0.32+0.1x0.28-0.1x0.270.0x0.15-0.1x0.270.0x
Liabilities-to-Equity0.320.0x0.30-0.1x0.49+0.3x0.430.0x0.37-0.2x0.44-0.1x0.22-0.2x0.390.0x
Asset Turnover0.000.0xN/A0.000.0x0.000.0x0.030.0xN/A0.000.00

Not reported in any period shown, so not listed: Gross Margin, FCF Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Centessa Pharmaceuticals plc American CNTA FY2025 $15.0M -$197.5M N/A N/A 65/100
Telix Pharmaceuticals Limited TLX FY2025 $803.8M -$7.1M -0.9% $3.1B 44/100
Scholar Rock Holding Corporation SRRK FY2025 $0 -$377.9M N/A $5.3B —
Immunovant, Inc. IMVT FY2026 N/A -$505.6M N/A $6.1B —
Viking Therapeutics, Inc VKTX FY2025 $0 -$359.6M N/A $3.2B —

Frequently Asked Questions

What is Centessa Pharmaceuticals plc American's annual revenue?

Centessa Pharmaceuticals plc American (CNTA) reported $15.0M in total revenue for fiscal year 2025. The change from the previous fiscal year is not meaningful, because that year’s figure was zero or negative. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Is Centessa Pharmaceuticals plc American profitable?

No, Centessa Pharmaceuticals plc American (CNTA) reported a net loss of $197.5M in fiscal year 2025.

What is Centessa Pharmaceuticals plc American's earnings per share (EPS)?

Centessa Pharmaceuticals plc American (CNTA) reported diluted earnings per share of -$1.46 for fiscal year 2025. The change from the previous fiscal year is not meaningful, because that year’s figure was zero or negative. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Centessa Pharmaceuticals plc American (CNTA) had EBITDA of -$206.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Centessa Pharmaceuticals plc American (CNTA) had $61.3M in cash and equivalents against $110.1M in long-term debt.

Centessa Pharmaceuticals plc American (CNTA) has a return on equity of -37.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Centessa Pharmaceuticals plc American (CNTA) recorded an outflow of $194.2M in free cash flow during fiscal year 2025. The change from the previous fiscal year is not meaningful, because that year’s figure was zero or negative. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Centessa Pharmaceuticals plc American (CNTA) recorded an outflow of $193.8M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Centessa Pharmaceuticals plc American (CNTA) had $687.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Centessa Pharmaceuticals plc American (CNTA) invested $371K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Centessa Pharmaceuticals plc American (CNTA) invested $172.2M in research and development during fiscal year 2025.

Centessa Pharmaceuticals plc American (CNTA) had 155M shares outstanding as of fiscal year 2025.

Centessa Pharmaceuticals plc American (CNTA) had a current ratio of 8.57 as of fiscal year 2025, which is generally considered healthy.

Centessa Pharmaceuticals plc American (CNTA) had a debt-to-equity ratio of 0.21 as of fiscal year 2025. We compute it as long-term debt divided by total shareholder equity, where long-term debt is the noncurrent part of the company's borrowings, so debt due within the next twelve months is not counted.

Centessa Pharmaceuticals plc American (CNTA) had a liabilities-to-equity ratio of 0.30 as of fiscal year 2025, which is total liabilities divided by total shareholder equity. Total liabilities counts every obligation on the balance sheet (payables, deposits, insurance reserves and deferred taxes as well as borrowings), so this ratio usually runs well above debt-to-equity.

Centessa Pharmaceuticals plc American (CNTA) had a return on assets of -28.7% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2025, Centessa Pharmaceuticals plc American (CNTA) held $577.1M in cash, cash equivalents and investments, and reported an operating cash outflow of $193.8M over that year. Dividing the one by the other, the reported balance equals about 36 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Centessa Pharmaceuticals plc American (CNTA) has a Piotroski F-Score of 4 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Centessa Pharmaceuticals plc American (CNTA) reported a net loss of $197.5M while operations used $193.8M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Centessa Pharmaceuticals plc American (CNTA) reported an operating loss of $207.7M against $11.5M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Centessa Pharmaceuticals plc American (CNTA) scores 65 out of 100 on our Financial Health Score, indicating strong standing within its emerging companies peer group. The score is the average of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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