Registration
No. 333-248561
As
filed with the Securities and Exchange Commission on March 13, 2026
UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington,
D.C. 20549
POST-EFFECTIVE
AMENDMENT NO. 6 TO
FORM
F-1
REGISTRATION
STATEMENT UNDER THE SECURITIES ACT OF 1933
COSCIENS
Biopharma Inc.
(f/k/a
Aeterna Zentaris Inc.)
(Exact
name of registrant as specified in its charter)
N/A
(Translation
of Registrant’s name into English)
| Canada |
|
2834 |
|
N/A |
|
(State
or other jurisdiction
of
incorporation or
organization) |
|
(Primary
Standard
Industrial
Classification
Code
Number) |
|
(I.R.S.
Employer
Identification
Number) |
c/o
Borden Ladner Gervais, LLP
22
Adelaide St. West, Suite 3409
Bay
Adelaide Centre, East Tower
Toronto
ON M5H YE3, Canada
(Address,
including zip code, and telephone number,
Including
area code, of Registrant’s principal executive offices)
Giuliano
La Fratta
Chief
Financial Officer
COSCIENS
Biopharma Inc.
c/o
Borden Ladner Gervais, LLP
22
Adelaide St. West, Suite 3409
Bay
Adelaide Centre, East Tower
Toronto
ON M5H YE3, Canada
Telephone:
(843) 900-3223
(Name,
address, including zip code, and telephone number,
Including
area code, of agent for service)
Copies
to:
Scott
R. Saks, Esq.
Norton
Rose Fulbright US LLP
1301
Avenue of the Americas
New
York, New York 10019-6022
Telephone:
(212) 318-3151
Approximate
date of commencement of proposed sale to the public: Not applicable.
If
any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the
Securities Act of 1933, check the following box. ☐
If
this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, check the following
box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.
☐
If
this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the
Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐
If
this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the
Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐
Indicate
by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933.
Emerging
growth company ☐
If
an emerging growth company that prepares its financial statements in accordance with U.S. GAAP, indicate by check mark if the registrant
has elected not to use the extended transition period for complying with any new or revised financial accounting standards† provided
pursuant to Section 7(a)(2)(B) of the Securities Act. ☐
†
The term “new or revised financial accounting standard” refers to any update issued by the Financial Accounting Standards
Board to its Accounting Standards Codification after April 5, 2012.
EXPLANATORY
NOTE
DEREGISTRATION
OF SECURITIES
On September 2, 2020, COSCIENS Biopharma Inc. (f/k/a
Aeterna Zentaris Inc. ) (the “Company”) filed a Registration Statement on Form F-1 (File No. 333-248561) (the “Registration
Statement”), which was declared effective by the U.S. Securities and Exchange Commission (the “Commission”) on September
14, 2020, initially registering the disposition from time to time by the selling shareholders named in the Registration Statement of
up to 10,190,859 common shares, no par value per share, of the Company (“Shares”), consisting of (i) 9,320,907 Shares that
may have been acquired upon exercise of outstanding unregistered warrants previously issued by the Company in August 2020 which were
exercisable until February 5, 2026, (ii) 869,952 Shares that may have been acquired upon exercise of outstanding unregistered warrants
previously issued by the Company in August 2020 as placement agent consideration which were exercisable until August 3, 2025. All Shares of the Company carry rights to purchase additional Shares pursuant to a Shareholder Rights Plan Agreement
between the Company and Computershare Trust Company of Canada. Such purchase rights are attached to and trade with the Shares. The Registration
Statement also registered the purchase rights attached to the Shares registered under the Registration Statement.
This
Post-Effective Amendment No. 6 to Form F-1 relates to the Registration Statement. The Company has terminated the offering of the securities
pursuant to the Registration Statement in the United States. In accordance with undertakings contained in the Registration Statement
to remove by means of a post-effective amendment any securities that remain unsold at the termination of the offering, this Post-Effective
Amendment No. 6 hereby terminates the effectiveness of the Registration Statement and removes from registration any and all of such securities
registered and remaining unsold under the Registration Statement as of the date this Post-Effective Amendment No. 6 is declared effective
by the Commission.
SIGNATURES
Pursuant
to the requirements of the Securities Act of 1933, as amended, and Rule 478 promulgated thereunder, the Registrant certifies that it
has reasonable grounds to believe that it meets all of the requirements for filing on Form F-1 and has duly caused this
Post-Effective Amendment No. 6 to the Registration Statement on Form F-1 to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Montreal, Province of Quebec, on this 13th day of March, 2026.
| |
COSCIENS BIOPHARMA INC. |
| |
|
|
| |
By: |
/s/ Giuliano
La Fratta |
| |
Name: |
Giuliano La Fratta |
| |
Title: |
Chief Financial Officer |
Note:
No other person is required to sign this Post-Effective Amendment No. 6 to the Registration Statement in reliance upon Rule 478 promulgated
under the Securities Act of 1933, as amended.
