STOCK TITAN

Castle Biosciences (CSTL) CEO sells 39,016 shares after option exercise

(Very High)
(Negative)
Form Type
4

Rhea-AI Filing Summary

Castle Biosciences (CSTL) president and CEO Derek J. Maetzold reported option exercises and related share sales on August 4–5, 2026. He exercised options covering 22,902 common shares at $2.39 per share, then he and related family trusts sold a combined 39,016 shares at weighted-average prices around $30.68–$31.34 per share. These transactions were made pursuant to a Rule 10b5-1 trading plan adopted on December 3, 2025.

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Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 39,016 shs ($1.21M)
Approx. gross sale proceeds $1.21M
Approx. exercise cost $55K
Type Security Shares Price Value
Exercise Stock option (right to buy) F1, F15 2,546 $0.00 $0.00
Exercise Common Stock F1 2,546 $2.39 $6K
Sale Common Stock F1, F6 2,546 $30.681 $78K
Sale Common Stock F1, F6, F3 556 $30.681 $17K
Sale Common Stock F1, F6, F4 473 $30.681 $15K
Exercise Stock option (right to buy) F1, F15 20,356 $0.00 $0.00
Exercise Common Stock F1 20,356 $2.39 $49K
Sale Common Stock F1, F2 8,421 $30.788 $259K
Sale Common Stock F1, F2, F3 3,374 $30.788 $104K
Sale Common Stock F1, F2, F4 2,866 $30.788 $88K
Sale Common Stock F1, F5 11,935 $31.336 $374K
Sale Common Stock F1, F5, F3 4,782 $31.336 $150K
Sale Common Stock F1, F5, F4 4,063 $31.336 $127K
holding Common Stock F7 -- -- --
holding Common Stock F8 -- -- --
holding Common Stock F9 -- -- --
holding Common Stock F10 -- -- --
holding Common Stock F11 -- -- --
holding Common Stock F12 -- -- --
holding Common Stock F13 -- -- --
holding Common Stock F14 -- -- --
Holdings After Transaction: Stock option (right to buy) — 38,857 shares (Direct); Common Stock — 21,479 shares (Direct); Common Stock — 23,069 shares (Indirect, By The Maetzold Descendants 2020 Trust); Common Stock — 19,607 shares (Indirect, By Derek Maetzold 2020 Irrevocable Trust); Common Stock — 11,812 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk); Common Stock — 11,812 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold); Common Stock — 11,812 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold); Common Stock — 11,812 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold); Common Stock — 11,963 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 6); Common Stock — 27,862 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 7); Common Stock — 40,935 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 8); Common Stock — 23,216 shares (Indirect, DJM Grantor Retained Annuity Trust No. 9)
Footnotes (15)
  1. F1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
  2. F2. This transaction was executed in multiple trades at prices ranging from $30.000 to $30.995, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  3. F3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
  4. F4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
  5. F5. This transaction was executed in multiple trades at prices ranging from $31.010 to $31.650, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  6. F6. This transaction was executed in multiple trades at prices ranging from $30.400 to $31.175, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  7. F7. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
  8. F8. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  9. F9. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  10. F10. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  11. F11. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
  12. F12. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
  13. F13. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
  14. F14. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
  15. F15. The shares subject to the option are fully vested.
Total shares sold 39,016 shares Aggregate Castle Biosciences common shares sold by Maetzold and related trusts on Aug. 4–5, 2026
Options exercised 22,902 shares Common shares acquired upon stock option exercises on Aug. 4–5, 2026
Option exercise price $2.3900 per share Exercise price of stock options converted into common stock by Maetzold
Weighted-average sale price (F2) $30.7880 per share Common stock sales on Aug. 4, 2026; trades ranged from $30.000 to $30.995
Weighted-average sale price (F5) $31.3360 per share Common stock sales on Aug. 4, 2026; trades ranged from $31.010 to $31.650
Weighted-average sale price (F6) $30.6810 per share Common stock sales on Aug. 5, 2026; trades ranged from $30.400 to $31.175
Rule 10b5-1 plan adoption date December 3, 2025 Date Derek Maetzold adopted the trading plan governing these transactions
Rule 10b5-1 plan regulatory
"These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person"
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
weighted-average sale price financial
"The price reported above reflects the weighted-average sale price for multiple trades"
Grantor Retained Annuity Trust financial
"Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee"
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
irrevocable trust financial
"Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee"
An irrevocable trust is a legal arrangement where an owner transfers assets into a separate entity managed by a trustee and gives up the power to modify or reclaim those assets. For investors it matters because putting stock or other holdings into such a trust can change who controls and benefits from the assets, affect taxes and creditor protection, and influence how easy it is to sell or value those holdings—like placing valuables in a locked safe overseen by someone else.
beneficiaries financial
"The beneficiaries are various Maetzold 2018 Remainder Trusts identified as beneficiaries"
Beneficiaries are the people or organizations designated to receive benefits, such as money or assets, from a financial arrangement like a trust, insurance policy, or retirement plan. They matter to investors because choosing the right beneficiaries ensures that assets are passed on according to their wishes, providing financial security or support to loved ones when needed. Think of beneficiaries as the intended recipients of a gift or inheritance.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What transactions did CSTL CEO Derek Maetzold report in this Form 4?

Derek Maetzold reported exercising stock options for 22,902 Castle Biosciences common shares at $2.39 per share, then, together with related family trusts, selling a total of 39,016 shares at weighted-average prices between about $30.68 and $31.34 on August 4–5, 2026.

Were Derek Maetzold’s CSTL stock trades made under a Rule 10b5-1 plan?

Yes. The filing states the trades were made pursuant to a Rule 10b5-1 plan that Derek Maetzold adopted on December 3, 2025. Such plans pre-arrange trading activity, reducing the informational value of transaction timing for interpreting insider sentiment.

How many CSTL shares did Derek Maetzold sell, and at what prices?

Maetzold and related family trusts sold 39,016 Castle Biosciences common shares. Weighted-average sale prices reported were $30.681, $30.788, and $31.336 per share, each reflecting multiple trades within specified price ranges between $30.000 and $31.650.

What options did CSTL CEO Derek Maetzold exercise in this filing?

He exercised stock options for 22,902 common shares at an exercise price of $2.39 per share, with the options expiring on May 9, 2028. A footnote confirms the option shares were fully vested at the time of exercise.

Which trusts were involved in Derek Maetzold’s indirect CSTL share sales?

Indirect sales involved shares held by The Maetzold Descendants 2020 Trust and the Derek Maetzold 2020 Irrevocable Trust. Maetzold’s spouse or Maetzold himself serves as trustee, with various family members as beneficiaries, as detailed in the ownership footnotes.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last)(First)(Middle)
C/O CASTLE BIOSCIENCES, INC.
1500 W. PARKWOOD AVE SUITE 400

(Street)
FRIENDSWOOD TEXAS 77546

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Pres. & Chief Exec. Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/04/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/04/2026M(1)20,356A$2.3941,835D
Common Stock08/04/2026S(1)8,421D$30.788(2)33,414D
Common Stock08/04/2026S(1)3,374D$30.788(2)28,407IBy The Maetzold Descendants 2020 Trust(3)
Common Stock08/04/2026S(1)2,866D$30.788(2)24,143IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock08/04/2026S(1)11,935D$31.336(5)21,479D
Common Stock08/04/2026S(1)4,782D$31.336(5)23,625IBy The Maetzold Descendants 2020 Trust(3)
Common Stock08/04/2026S(1)4,063D$31.336(5)20,080IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock08/05/2026M(1)2,546A$2.3924,025D
Common Stock08/05/2026S(1)2,546D$30.681(6)21,479D
Common Stock08/05/2026S(1)556D$30.681(6)23,069IBy The Maetzold Descendants 2020 Trust(3)
Common Stock08/05/2026S(1)473D$30.681(6)19,607IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock11,812IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(7)
Common Stock11,812IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(8)
Common Stock11,812IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(9)
Common Stock11,812IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(10)
Common Stock11,963IBy DJM Grantor Retained Annuity Trust No. 6(11)
Common Stock27,862IBy DJM Grantor Retained Annuity Trust No. 7(12)
Common Stock40,935IBy DJM Grantor Retained Annuity Trust No. 8(13)
Common Stock23,216IDJM Grantor Retained Annuity Trust No. 9(14)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock option (right to buy)$2.3908/04/2026M(1)20,356 (15)05/09/2028Common Stock20,356$041,403D
Stock option (right to buy)$2.3908/05/2026M(1)2,546 (15)05/09/2028Common Stock2,546$038,857D
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
2. This transaction was executed in multiple trades at prices ranging from $30.000 to $30.995, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
5. This transaction was executed in multiple trades at prices ranging from $31.010 to $31.650, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
6. This transaction was executed in multiple trades at prices ranging from $30.400 to $31.175, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
7. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
10. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
11. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
12. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
13. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
14. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
15. The shares subject to the option are fully vested.
Remarks:
/s/ Frank Stokes, Attorney-in-fact08/06/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)