STOCK TITAN

Castle Biosciences (NASDAQ: CSTL) CEO sells stock under 10b5-1 plan

(Moderate)
(Negative)
Form Type
4

Rhea-AI Filing Summary

CASTLE BIOSCIENCES INC (CSTL) CEO Derek J. Maetzold reported an option exercise and related share sales. He exercised a stock option for 1,100 shares of common stock at $2.39 per share, receiving 1,100 shares that were then sold at $30.02 per share. Additional sales totaling 7,232 shares of common stock were made by several trusts for which he or his spouse serves as trustee or beneficiary, at the same weighted-average price. After these transactions, he holds 37,757 shares directly, and various family and grantor retained annuity trusts hold between 11,534 and 40,935 shares each. All trades were made under a Rule 10b5-1 plan adopted on December 3, 2025, and the option shares exercised were fully vested.

Positive

  • None.

Negative

  • None.
Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 7,232 shs ($217K)
Approx. gross sale proceeds $217K
Approx. exercise cost $3K
Type Security Shares Price Value
Exercise Stock option (right to buy) F1, F13 1,100 $0.00 $0.00
Exercise Common Stock F1 1,100 $2.39 $3K
Sale Common Stock F1, F2 1,100 $30.02 $33K
Sale Common Stock F1, F2, F3 2,714 $30.02 $81K
Sale Common Stock F1, F2, F4 2,306 $30.02 $69K
Sale Common Stock F1, F2, F5 278 $30.02 $8K
Sale Common Stock F1, F2, F6 278 $30.02 $8K
Sale Common Stock F1, F2, F7 278 $30.02 $8K
Sale Common Stock F1, F2, F8 278 $30.02 $8K
holding Common Stock F9 -- -- --
holding Common Stock F10 -- -- --
holding Common Stock F11 -- -- --
holding Common Stock F12 -- -- --
Holdings After Transaction: Stock option (right to buy) — 37,757 shares (Direct); Common Stock — 21,479 shares (Direct); Common Stock — 20,355 shares (Indirect, By The Maetzold Descendants 2020 Trust); Common Stock — 17,301 shares (Indirect, By Derek Maetzold 2020 Irrevocable Trust); Common Stock — 11,534 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk); Common Stock — 11,534 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold); Common Stock — 11,534 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold); Common Stock — 11,534 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold); Common Stock — 11,963 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 6); Common Stock — 27,862 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 7); Common Stock — 40,935 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 8); Common Stock — 23,216 shares (Indirect, DJM Grantor Retained Annuity Trust No. 9)
Footnotes (13)
  1. F1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
  2. F2. This transaction was executed in multiple trades at prices ranging from $29.73 to $30.55, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  3. F3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
  4. F4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
  5. F5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
  6. F6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  7. F7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  8. F8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  9. F9. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
  10. F10. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
  11. F11. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
  12. F12. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
  13. F13. The shares subject to the option are fully vested.
Option shares exercised 1,100 shares Stock option for common stock exercised on August 14, 2026
Option exercise price $2.39 per share Conversion or exercise price of the stock option
Sale price (weighted-average) $30.02 per share Reported sale price for common stock transactions on August 14, 2026
Total shares sold 7,232 shares Net shares sold across reported sale transactions
Direct holdings after transactions 37,757 shares Common stock held directly by Derek J. Maetzold after transactions
Trust holding – DJM GRAT No. 8 40,935 shares CSTL common stock held indirectly by DJM Grantor Retained Annuity Trust No. 8
Trust holding – DJM GRAT No. 7 27,862 shares CSTL common stock held indirectly by DJM Grantor Retained Annuity Trust No. 7
Option expiration date May 9, 2028 Expiration date of the stock option exercised
Rule 10b5-1 plan regulatory
"These transactions were made pursuant to a Rule 10b5-1 plan adopted"
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
Grantor Retained Annuity Trust financial
"Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting"
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
weighted-average sale price financial
"executed in multiple trades at prices ranging from $29.73 to $30.55, inclusive. The price reported above reflects the weighted-average sale price"
stock option (right to buy) financial
"security_title: Stock option (right to buy)"

FAQ

What did CSTL CEO Derek Maetzold report in this Form 4 filing?

He reported exercising an option for 1,100 CSTL shares at $2.39 and selling those shares, plus additional 7,232 shares held through various trusts, all on August 14, 2026.

At what prices were the CSTL shares sold in this Form 4?

The reported CSTL share sales used a weighted-average price of $30.02 per share, with individual trades executed between $29.73 and $30.55, as disclosed in a footnote.

How many CSTL shares did Derek Maetzold exercise and sell from options?

He exercised a stock option covering 1,100 CSTL shares at an exercise price of $2.39 per share and sold the resulting 1,100 shares at a weighted-average price of $30.02 per share.

How many CSTL shares does Derek Maetzold hold directly after these transactions?

Following the reported transactions, Derek Maetzold holds 37,757 CSTL common shares directly. Additional shares are held indirectly through several family and grantor retained annuity trusts for which he or his spouse acts as trustee or beneficiary.

Were the CSTL insider transactions made under a Rule 10b5-1 plan?

Yes. A footnote states all reported transactions were made under a Rule 10b5-1 trading plan adopted by Derek Maetzold on December 3, 2025, indicating they followed a pre-established schedule.

What indirect CSTL holdings by trusts are reported in this Form 4?

Indirect CSTL holdings include trusts such as The Maetzold Descendants 2020 Trust with 20,355 shares and DJM Grantor Retained Annuity Trusts No. 6, 7, 8, and 9 holding between 11,963 and 40,935 shares each, with Maetzold typically serving as trustee.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last)(First)(Middle)
C/O CASTLE BIOSCIENCES, INC.
1500 W. PARKWOOD AVE SUITE 400

(Street)
FRIENDSWOOD TEXAS 77546

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Pres. & Chief Exec. Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/14/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/14/2026M(1)1,100A$2.3922,579D
Common Stock08/14/2026S(1)1,100D$30.02(2)21,479D
Common Stock08/14/2026S(1)2,714D$30.02(2)20,355IBy The Maetzold Descendants 2020 Trust(3)
Common Stock08/14/2026S(1)2,306D$30.02(2)17,301IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock08/14/2026S(1)278D$30.02(2)11,534IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(5)
Common Stock08/14/2026S(1)278D$30.02(2)11,534IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(6)
Common Stock08/14/2026S(1)278D$30.02(2)11,534IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(7)
Common Stock08/14/2026S(1)278D$30.02(2)11,534IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(8)
Common Stock11,963IBy DJM Grantor Retained Annuity Trust No. 6(9)
Common Stock27,862IBy DJM Grantor Retained Annuity Trust No. 7(10)
Common Stock40,935IBy DJM Grantor Retained Annuity Trust No. 8(11)
Common Stock23,216IDJM Grantor Retained Annuity Trust No. 9(12)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock option (right to buy)$2.3908/14/2026M(1)1,100 (13)05/09/2028Common Stock1,100$037,757D
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
2. This transaction was executed in multiple trades at prices ranging from $29.73 to $30.55, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
10. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
11. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
12. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
13. The shares subject to the option are fully vested.
Remarks:
/s/ Frank Stokes, Attorney-in-fact08/18/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)