[Form 4] CryoPort, Inc. Insider Trading Activity

Rhea-AI Filing Summary

CryoPort insider exercise and share ownership update. Jerrell Shelton, President and CEO and a director of CryoPort, exercised options on 08/13/2025 to acquire 25,000 shares of common stock at an exercise price of $5. After this cash exercise, Shelton beneficially owns 1,062,419 shares. The option grant referenced vests monthly over 48 months beginning 08/19/2015; the exercised options were part of that schedule. The filing indicates the exercise was a cash exercise and there was no immediate sale of the underlying shares.

Positive

• Insider acquisition: Jerrell Shelton exercised options to acquire 25,000 shares, increasing direct beneficial ownership to 1,062,419 shares
• No immediate sale: The filing states there was no subsequent sale of the underlying shares after the cash exercise

Negative

• None.

Insights

Financial Analyst

TL;DR: Insider purchased 25,000 shares via option exercise, modestly increasing direct holdings to 1,062,419 shares.

The reported transaction is a routine cash exercise of previously granted options rather than an open-market purchase. Such exercises convert option rights into common shares without immediate liquidation, and the filing confirms no sale followed the exercise. For investors, this is a neutral-to-slightly positive signal because management retained newly acquired shares, but it does not, by itself, indicate a material change to the company’s capital structure or outstanding share count.

Corporate Governance Expert

TL;DR: CEO and director exercised vested options under an existing schedule; disclosure is compliant and routine.

The Form 4 shows the exercise stems from an option grant with 1/48 monthly vesting beginning 08/19/2015, indicating long-standing compensation arrangements. The signature and timely filing preserve Section 16 compliance. There is no indication of a Section 10b5-1 plan or immediate disposition, so governance practices appear standard for executive option exercises.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

SHELTON JERRELL

(Last) (First) (Middle)

C/O CRYOPORT INC.

112 WESTWOOD PLACE, SUITE 350

(Street)

BRENTWOOD TN 37027

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Cryoport, Inc. [ CYRX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President, CEO

3. Date of Earliest Transaction (Month/Day/Year)
08/13/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/13/2025		M		25,000(1)	A	$5	1,062,419	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$5	08/13/2025		M			25,000(1)	(2)	08/20/2025	Common Stock	25,000	$0.00	0	D

Explanation of Responses:

1. This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

2. 1/48 of the options vested on the 19th of each month for forty-eight months beginning on 8/19/2015.

	/s/ Jerrell Shelton	08/15/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transaction did CryoPort (CYRX) insider Jerrell Shelton report?

Shelton reported a cash exercise of stock options on 08/13/2025 to acquire 25,000 shares at an exercise price of $5 per share.

How many CryoPort shares does Jerrell Shelton own after the transaction?

After the reported transaction Shelton beneficially owns 1,062,419 shares of common stock.

Were the exercised options part of a regular vesting schedule?

Yes. The options vest at 1/48 of the grant on the 19th of each month for 48 months starting 08/19/2015.

Did Shelton sell any shares immediately after exercising the options?

No. The filing explains the transaction was a cash exercise without a subsequent sale of the underlying shares.

When was the Form 4 signed and filed?

The Form 4 includes Shelton's signature dated 08/15/2025 and reports the transaction date as 08/13/2025.