[Form 4] CryoPort, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Cryoport (CYRX) filed a routine Form 4 detailing insider activity by President & CEO Jerrell Shelton. On 06/24/2025 he exercised 16,344 options at $5 and immediately sold the same number of shares at a weighted-average $7.06, generating roughly $115 k in gross proceeds. On 06/25/2025 he exercised an additional 25,000 options without selling. Post-transaction ownership stands at ~937,000 shares. The sale represents less than 2% of his holdings and was executed under a pre-established 10b5-1 plan, indicating no material shift in insider sentiment.

Insights

Securities Compliance Analyst

CEO Jerrell Shelton exercised options and sold partial shares while maintaining substantial holdings, indicating routine insider activity.

In this Form 4 filing, Cryoport's President and CEO Jerrell Shelton reported multiple transactions involving company stock options. On June 24, 2025, Shelton exercised 16,344 options at $5 per share and immediately sold those shares at an average price of $7.0586 through a pre-established Rule 10b5-1 trading plan (adopted June 3, 2025). The following day, he exercised an additional 25,000 options at $5 per share but retained these shares. The options originated from grants that began vesting in August 2015.

After these transactions, Shelton still maintains direct ownership of 937,419 shares and retains 125,000 unexercised stock options. The exercise-and-sell transaction netted him approximately $33,700 in pre-tax profits (difference between $5 strike price and $7.0586 sale price), while the second transaction represents a significant retention of shares acquired through options. The execution through a predetermined trading plan suggests these sales were scheduled in advance rather than in response to any immediate company developments. Despite the partial sale, Shelton continues to maintain substantial equity exposure to Cryoport, indicating ongoing alignment with shareholder interests.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

SHELTON JERRELL

(Last) (First) (Middle)

C/O CRYOPORT INC.

112 WESTWOOD PLACE, SUITE 350

(Street)

BRENTWOOD TN 37027

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Cryoport, Inc. [ CYRX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President, CEO

3. Date of Earliest Transaction (Month/Day/Year)
06/24/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/24/2025		M		16,344(1)	A	$5	928,763	D
Common Stock	06/24/2025		S		16,344(1)	D	$7.0586(2)	912,419	D
Common Stock	06/25/2025		M		25,000(3)	A	$5	937,419	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$5	06/24/2025		M			16,344(1)	(4)	08/20/2025	Common Stock	16,344	$0.00	150,000	D
Stock Option (right to buy)	$5	06/25/2025		M			25,000(3)	(4)	08/20/2025	Common Stock	25,000	$0.00	125,000	D

Explanation of Responses:

1. This transaction occurred automatically pursuant to a trading plan adopted by the reporting person on June 3, 2025.

2. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.61 to $7.31, inclusive.

3. This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

4. 1/48 of the options vested on the 19th of each month for forty-eight months beginning on 8/19/2015.

Remarks:

With respect to prices reported as weighted average prices in Table I, the reporting person undertakes to provide to Cryoport, Inc., any security holder of Cryoport, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the applicable footnotes to this Form 4.

	/s/ Jerrell Shelton	06/26/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many Cryoport shares did CEO Jerrell Shelton sell on 06/24/2025?

He sold 16,344 shares at a weighted-average price of $7.06.

Did the CEO purchase or exercise additional Cryoport shares?

Yes, he exercised 41,344 options at $5—16,344 on 06/24/2025 and 25,000 on 06/25/2025.

What is Jerrell Shelton’s total Cryoport shareholding after the transactions?

He now directly owns approximately 937,419 shares.

Was the Cryoport insider trade executed under a 10b5-1 trading plan?

Yes. The Form 4 states the transactions occurred automatically under a plan adopted on June 3, 2025.