[Form 4] CryoPort, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Jerrell Shelton, President, CEO, and Director of Cryoport (CYRX), executed significant stock option exercises and sales between June 17-20, 2025, as part of a pre-planned trading arrangement.

Key transactions include:

• Exercised options for 389,720 total shares at $5.00 strike price
• Sold 339,720 shares at weighted average prices between $6.33-$6.97
• Retained 50,000 shares from initial exercise
• Maintained beneficial ownership of 912,419 shares post-transactions

The transactions were conducted under a Rule 10b5-1 trading plan established on June 3, 2025. The exercised options were originally granted in August 2015 with a 48-month vesting schedule. After all transactions, Shelton continues to hold 166,344 unexercised stock options with an August 2025 expiration date.

Positive

• CEO Jerrell Shelton maintains significant ownership with 912,419 shares after transactions, demonstrating continued alignment with shareholders

Negative

• CEO Jerrell Shelton sold a total of 339,720 shares worth approximately $2.3M through multiple transactions at prices between $6.33-$6.97, executed via a 10b5-1 trading plan

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

SHELTON JERRELL

(Last) (First) (Middle)

C/O CRYOPORT INC.

112 WESTWOOD PLACE, SUITE 350

(Street)

BRENTWOOD TN 37027

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Cryoport, Inc. [ CYRX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President, CEO

3. Date of Earliest Transaction (Month/Day/Year)
06/17/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/17/2025		M		50,000(1)	A	$5	912,419	D
Common Stock	06/17/2025		M		151,304(2)	A	$5	1,063,723	D
Common Stock	06/17/2025		S		151,304(2)	D	$6.8056(3)	912,419	D
Common Stock	06/18/2025		M		119,281(2)	A	$5	1,031,700	D
Common Stock	06/18/2025		S		119,281(2)	D	$6.812(4)	912,419	D
Common Stock	06/20/2025		M		69,135(2)	A	$5	981,554	D
Common Stock	06/20/2025		S		69,135(2)	D	$6.4732(5)	912,419	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$5	06/17/2025		M			50,000(1)	(6)	08/20/2025	Common Stock	50,000	$0.00	506,064	D
Stock Option (right to buy)	$5	06/17/2025		M			151,304(2)	(6)	08/20/2025	Common Stock	151,304	$0.00	354,760	D
Stock Option (right to buy)	$5	06/18/2025		M			119,281(2)	(6)	08/20/2025	Common Stock	119,281	$0.00	235,479	D
Stock Option (right to buy)	$5	06/20/2025		M			69,135(2)	(6)	08/20/2025	Common Stock	69,135	$0.00	166,344	D

Explanation of Responses:

1. This transaction involved a cash exercise of a stock option without a subsequent sale of the underlying shares of common stock.

2. This transaction occurred automatically pursuant to a trading plan adopted by the reporting person on June 3, 2025.

3. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.57 to $6.96, inclusive.

4. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.62 to $6.97, inclusive.

5. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.33 to $6.83, inclusive.

6. 1/48 of the options vested on the 19th of each month for forty-eight months beginning on 8/19/2015.

Remarks:

With respect to prices reported as weighted average prices in Table I, the reporting person undertakes to provide to Cryoport, Inc., any security holder of Cryoport, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the applicable footnotes to this Form 4.

	/s/ Jerrell Shelton	06/20/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transactions did CYRX CEO Jerrell Shelton report on June 17-20, 2025?

CEO Jerrell Shelton exercised stock options and sold shares in multiple transactions: On June 17, he exercised 201,304 options at $5 and sold 151,304 shares at avg. $6.81. On June 18, he exercised 119,281 options at $5 and sold them at avg. $6.81. On June 20, he exercised 69,135 options at $5 and sold them at avg. $6.47. He retained 50,000 shares from the first exercise.

How many CYRX shares does CEO Jerrell Shelton own after these transactions?

After completing all reported transactions, CEO Jerrell Shelton directly owns 912,419 shares of CYRX common stock. He also holds 166,344 stock options that remain unexercised.

What was the exercise price of CYRX stock options in Shelton's June 2025 transactions?

All stock options exercised by Jerrell Shelton had an exercise price of $5.00 per share. These options were originally granted in 2015 with a vesting schedule of 1/48th of the options vesting monthly over 48 months beginning August 19, 2015.

Were CYRX CEO Shelton's stock sales part of a pre-planned trading program?

Yes, the sales transactions were executed automatically pursuant to a trading plan adopted by Jerrell Shelton on June 3, 2025, following Rule 10b5-1 trading plan guidelines. This excludes the initial 50,000 share option exercise where he retained the shares.

What was the selling price range for CYRX shares in Shelton's June 2025 transactions?

The shares were sold at varying prices: June 17 sales ranged from $6.57 to $6.96 (avg. $6.81), June 18 sales ranged from $6.62 to $6.97 (avg. $6.81), and June 20 sales ranged from $6.33 to $6.83 (avg. $6.47).