Insider plans sale of 150,000 common shares

A person named Carole Ho has filed a Rule 144 notice indicating an intention to sell 150,000 shares of common stock through Morgan Stanley Smith Barney LLC on NASDAQ.

Accepted by SEC EDGAR 02/04/2026 - 04:16 PM EST Learn about SEC filing dates

Rhea-AI Filing Summary

A person named Carole Ho has filed a Rule 144 notice indicating an intention to sell 150,000 shares of common stock through Morgan Stanley Smith Barney LLC on NASDAQ. The filing lists an aggregate market value of 3,176,970.00 for these shares and shows 146,661,833 shares outstanding.

The notice also reports that on 02/04/2026 options were exercised under a registered plan to acquire 36,042 and 113,958 common shares for cash. In the past three months, the same seller disposed of 150,000 common shares for 3,324,060.00.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does the DNLI Rule 144 filing disclose?

The filing shows a planned sale of 150,000 common shares through Morgan Stanley Smith Barney LLC on NASDAQ, with an aggregate market value of about 3,176,970.00, plus recent option exercises and prior share sales by the same seller.

How many DNLI shares is the insider planning to sell under this notice?

The notice covers a planned sale of 150,000 common shares. These shares are to be sold on the NASDAQ market, with the filing indicating an aggregate market value of 3,176,970.00 based on the quoted market price at the time of the notice.

What recent DNLI insider sales are reported in the past three months?

The document reports that Carole Ho sold 150,000 common shares on 02/03/2026, generating gross proceeds of 3,324,060.00. This historical sale information is required to be aggregated with the newly planned sales under Rule 144 disclosure rules.

What option exercises related to DNLI stock are disclosed in this filing?

On 02/04/2026, options under a registered plan were exercised to acquire 36,042 and 113,958 common shares for cash. These acquisitions are listed as the source of the securities that may be sold under the Rule 144 notice.

Which broker is handling the planned DNLI share sale under Rule 144?

The planned sale of 150,000 common shares is to be handled by Morgan Stanley Smith Barney LLC Executive Financial Services, located at 1 New York Plaza, 8th Floor, New York, NY 10004, with the shares listed for trading on the NASDAQ exchange.

How many DNLI shares are reported as outstanding in the Rule 144 notice?

The filing states that there are 146,661,833 common shares outstanding. This figure provides context for the planned 150,000-share sale but is a baseline capital structure number rather than an amount being registered or newly issued.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001724605
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	DENALI THERAPEUTICS INC.
SEC File Number	001-38311
Address of Issuer	161 Oyster Point Blvd South San Francisco CALIFORNIA 94080
Phone	(650) 866-8547
Name of Person for Whose Account the Securities are To Be Sold	CAROLE HO
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Former Affiliate

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	150000	3176970.00	146661833	02/04/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	02/04/2026	Exercise of options under a registered plan	Issuer			36042	02/04/2026	Cash
Common	02/04/2026	Exercise of options under a registered plan	Issuer			113958	02/04/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
CAROLE HO 161 Oyster Point Blvd South San Francisco CA 94080	Common	02/03/2026	150000	3324060.00

144: Remarks and Signature

Remarks
Date of Notice	02/04/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Carole Ho
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)