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Foresite Capital discloses 7.7% Eikon Therapeutics (EIKN) stake in Schedule 13G

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Form Type
SCHEDULE 13G

Rhea-AI Filing Summary

Eikon Therapeutics, Inc. received a Schedule 13G filing from a group of Foresite Capital investment funds and their affiliated managers, disclosing a significant passive ownership stake in its common stock. The filing reports that various Foresite Capital funds and entities collectively attribute beneficial ownership to James B. Tananbaum of 4,148,519 shares, representing 7.7% of the common stock, based on 53,984,337 shares outstanding as of February 4, 2026.

Individual Foresite vehicles report smaller positions, including Foresite Capital Fund IV, L.P. with 1,960,774 shares (3.6%), Foresite Capital Fund V, L.P. with 1,353,168 shares (2.5%), Foresite Capital Opportunity Fund V, L.P. with 425,852 shares (0.8%), and Foresite Capital VI-A, LLC with 408,725 shares (0.8%). Each entity reports sole voting and dispositive power over its shares, with those powers ultimately attributable to Tananbaum through the general partner and managing member structures.

The Reporting Persons certify that the securities were not acquired and are not held for the purpose or effect of changing or influencing control of Eikon Therapeutics, indicating a passive investment posture consistent with a Schedule 13G filing.

Positive

  • None.

Negative

  • None.





Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)






SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 1,960,774 shares, except that Foresite Capital Management IV, LLC ("FCM IV"), the general partner of Foresite Capital Fund IV, L.P. ("FCF IV"), may be deemed to have sole power to vote these shares, and James Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,960,774 shares, except that FCM IV, the general partner of FCF IV, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM IV, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of Eikon Therapeutics, Inc. (the "Issuer") as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 1,960,774 shares, all of which are directly owned by FCF IV. FCM IV, the general partner of FCF IV, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM IV, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,960,774 shares, all of which are directly owned by FCF IV. FCM IV, the general partner of FCF IV, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM IV, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 1,353,168 shares, except that Foresite Capital Management V, LLC ("FCM V"), the general partner of Foresite Capital Fund V, L.P. ("FCF V"), may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,353,168 shares, except that FCM V, the general partner of FCF V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 1,353,168 shares, all of which are directly owned by FCF V. FCM V, the general partner of FCF V, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,353,168 shares, all of which are directly owned by FCF V. FCM V, the general partner of FCF V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 425,852 shares, except that Foresite Capital Opportunity Management V, LLC ("FCM Opp V"), the general partner of Foresite Capital Opportunity Fund V, L.P. ("FCF Opp V"), may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 425,852 shares, except that FCM Opp V, the general partner of FCF Opp V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 425,852 shares, all of which are directly owned by FCF Opp V. FCM Opp V, the general partner of FCF Opp V, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 425,852 shares, all of which are directly owned by FCF Opp V. FCM Opp V, the general partner of FCF Opp V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 408,725 shares, except that Foresite Capital VI-A Management, LLC ("FCM VI-A"), the managing member of Foresite Capital VI-A, LLC ("FC VI-A"), may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FC VI-A, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 408,725 shares, except that FCM VI-A, the managing member of FC VI-A, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM VI-A, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 408,725 shares, all of which are directly owned by FC VI-A. FCM VI-A, the managing member of FC VI-A, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM VI-A, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 408,725 shares, all of which are directly owned by FC VI-A. FCM VI-A, the managing member of FC VI-A, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM VI-A, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G




Comment for Type of Reporting Person: Note to Row 5: 4,148,519 shares, of which 1,960,774 shares are directly owned by FCF IV, 1,353,168 shares are directly owned by FCF V, 425,852 shares are directly owned by FCF Opp V and 408,725 shares are directly owned by FC VI-A. Tananbaum is the managing member of each of FCM IV, which is the general partner of FCF IV, FCM V, which is the general partner of FCF V, FCM Opp V, which is the general partner of FCF Opp V and FCM VI-A, which is the managing member of FC VI-A. Tananbaum may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 4,148,519 shares, of which 1,960,774 shares are directly owned by FCF IV, 1,353,168 shares are directly owned by FCF V, 425,852 shares are directly owned by FCF Opp V and 408,725 shares are directly owned by FC VI-A. Tananbaum is the managing member of each of FCM IV, which is the general partner of FCF IV, FCM V, which is the general partner of FCF V, FCM Opp V, which is the general partner of FCF Opp V and FCM VI-A, which is the managing member of FC VI-A. Tananbaum may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.


SCHEDULE 13G



Foresite Capital Fund IV, L.P.
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member of the General Partner
Date:02/11/2026
Foresite Capital Management IV, LLC
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member
Date:02/11/2026
Foresite Capital Fund V, L.P.
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member of the General Partner
Date:02/11/2026
Foresite Capital Management V, LLC
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member
Date:02/11/2026
Foresite Capital Opportunity Fund V, L.P.
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member of the General Partner
Date:02/11/2026
Foresite Capital Opportunity Management V, LLC
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member
Date:02/11/2026
Foresite Capital VI-A, LLC
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member of the Managing Member
Date:02/11/2026
Foresite Capital VI-A Management, LLC
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum, Managing Member
Date:02/11/2026
James B. Tananbaum
Signature:/s/ James Tananbaum
Name/Title:James Tananbaum
Date:02/11/2026
Exhibit Information

Exhibit A Agreement of Joint Filing The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Common Stock of the Issuer shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13G. Date: February 11, 2026 FORESITE CAPITAL FUND IV, L.P. By: FORESITE CAPITAL MANAGEMENT IV, LLC Its: General Partner By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL MANAGEMENT IV, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL FUND V, L.P. By: FORESITE CAPITAL MANAGEMENT V, LLC Its: General Partner By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL MANAGEMENT V, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL OPPORTUNITY FUND V, L.P. By: FORESITE CAPITAL OPPORTUNITY MANAGEMENT V, LLC Its: Managing Member By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL OPPORTUNITY MANAGEMENT V, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL VI-A, LLC By: FORESITE CAPITAL VI-A MANAGEMENT, LLC Its: Managing Member By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL VI-A MANAGEMENT, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member JAMES TANANBAUM By: /s/ James Tananbaum Name: James Tananbaum

FAQ

What ownership stake in Eikon Therapeutics (EIKN) does Foresite Capital report?

Foresite-related entities attribute beneficial ownership of 4,148,519 Eikon Therapeutics shares to James B. Tananbaum, representing 7.7% of the common stock. This percentage is based on 53,984,337 shares outstanding as of February 4, 2026, per Eikon’s referenced prospectus.

Which Foresite Capital funds are included in this Eikon Therapeutics Schedule 13G?

The filing covers Foresite Capital Fund IV, L.P., Foresite Capital Fund V, L.P., Foresite Capital Opportunity Fund V, L.P., Foresite Capital VI-A, LLC and their respective management LLCs, plus James B. Tananbaum, who is managing member of the relevant general partners and managers.

How many Eikon Therapeutics shares does each key Foresite fund beneficially own?

Foresite Capital Fund IV, L.P. reports 1,960,774 shares (3.6%), Foresite Capital Fund V, L.P. 1,353,168 shares (2.5%), Foresite Capital Opportunity Fund V, L.P. 425,852 shares (0.8%), and Foresite Capital VI-A, LLC 408,725 shares (0.8%), each with sole voting and dispositive power.

Is the Foresite Capital stake in Eikon Therapeutics a passive investment?

Yes. The Reporting Persons certify the shares were not acquired and are not held to change or influence control of Eikon Therapeutics. This language, included in Item 10, aligns with a passive investment stance typical for a Schedule 13G filing.

How was the 7.7% ownership percentage in Eikon Therapeutics calculated?

The 7.7% figure is based on 4,148,519 shares beneficially owned by James B. Tananbaum divided by 53,984,337 common shares outstanding of Eikon Therapeutics as of February 4, 2026, using outstanding share data from the company’s referenced 424B4 filing.

Who ultimately controls voting and disposition of the reported Eikon Therapeutics shares?

The filing states that James B. Tananbaum, as managing member of the various Foresite management entities, may be deemed to have sole power to vote and dispose of the reported shares, even though they are directly owned by the individual Foresite funds and entities.
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Biotechnology
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