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Evaxion (NASDAQ: EVAX) to share EVX-01 and glioblastoma data at AACR

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Rhea-AI Filing Summary

Evaxion A/S, a clinical-stage TechBio company using its AI-Immunology™ platform to develop vaccines, will present two scientific abstracts at the AACR Annual Meeting in San Diego on April 17-22, 2026. This update is furnished on a Form 6-K and incorporated into several of Evaxion’s U.S. registration statements.

One abstract covers new biomarker and immunogenicity data for EVX-01, a personalized cancer vaccine being evaluated in a phase 2 trial for advanced melanoma in combination with MSD’s anti-PD-1 therapy KEYTRUDA® (pembrolizumab). Each enrolled patient receives an individually designed vaccine based on their biology.

The second abstract discusses using AI-Immunology™ to identify endogenous retrovirus-derived neoantigens for personalized vaccines targeting glioblastoma, a severe brain cancer with limited treatment options. Evaxion will also take part in the AACR Oncology Industry Partnering event to explore potential business and scientific collaborations.

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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Form 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of March 2026

Commission File Number: 001-39950

Evaxion A/S
(Exact Name of Registrant as Specified in Its Charter)

Dr. Neergaards Vej 5f
DK-2970 Hoersholm
Denmark

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F [ X ]      Form 40-F [   ]


INCORPORATION BY REFERENCE

This report on Form 6-K shall be deemed to be incorporated by reference in Evaxion A/S’s registration statements on Form S-8 (File No. 333-255064), on Form F-3 (File No. 333-265132), on Form F-1, as amended (File No. 333-266050), Form F-1 (File No. 333-276505), Form F-1 (File No. 333-279153), Form F-1 (File No. 333-283304), and Form F-3 (File No. 333- 285778), including any prospectuses forming a part of such registration statements and to be a part thereof from the date on which this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished.

Press Release

On March 17, 2026, Evaxion A/S (the “Company”), a clinical-stage TechBio company specializing in developing AI-Immunology™ powered vaccines, issued a press release titled "Evaxion to present new data at AACR Annual Meeting". A copy of the press release is furnished as Exhibit 99.1 to this report on Form 6-K.

Exhibits

Exhibit No. Description
   
99.1 Evaxion to present new data at AACR Annual Meeting


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

   Evaxion A/S
   (Registrant)
    
   
Date: March 17, 2026 By:/s/ Helen Tayton-Martin    
   Helen Tayton-Martin
   Chief Executive Officer
   

EXHIBIT 99.1

Evaxion to present new data at AACR Annual Meeting

  • Two abstracts accepted for presentation
  • One abstract on new additional biomarker and immunogenicity data for personalized cancer vaccine EVX-01
  • Another abstract on the use of Evaxion’s AI-Immunology™ platform in developing a personalized cancer vaccine strategy for glioblastoma (brain cancer)
  • Evaxion will also participate in the AACR Oncology Industry Partnering event ahead of the annual meeting

COPENHAGEN, Denmark, March 17, 2026 - Evaxion A/S (NASDAQ: EVAX) (“Evaxion”), a clinical-stage TechBio company developing novel vaccines with its pioneering AI-Immunology™ platform, announces two abstracts accepted for presentation at the American Association for Cancer Research (AACR) Annual Meeting taking place in San Diego, California, April 17-22, 2026.

One abstract will include new biomarker and immunogenicity data for cancer vaccine EVX-01. Designed with Evaxion’s AI-Immunology™ platform, EVX-01 is a personalized cancer vaccine currently being evaluated as a treatment for advanced melanoma (skin cancer).

The data stems from the phase 2 trial investigating EVX-01 in combination with MSD’s (Merck & Co., Inc., Rahway, NJ, USA) anti-PD-1 therapy, KEYTRUDA® (pembrolizumab) in patients with advanced melanoma. Each patient enrolled in the trial has received a unique vaccine designed and manufactured based on their individual biology. KEYTRUDA® is a registered trademark of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA.

The other abstract includes data on the use of AI-Immunology™ to identify endogenous retrovirus (ERV)-derived neoantigens to include in personalized vaccines to treat glioblastoma, a deadly brain cancer, for which limited therapeutic options exist.

In line with our strategy to identify potential partners and opportunities for both business partnerships and scientific collaborations, we will also participate in the AACR Oncology Industry Partnering event taking place ahead of the annual meeting.

Presentations details:
Abstract title: AI-designed personalized neoantigen vaccine, EVX-01, induces durable de novo T-cell responses in advanced melanoma patients
Poster#: 7741
Session category: Clinical research
Session title: Immune response to therapies
Location: Poster section 42
Date/Time: April 22, 2026, at 9am-12pm CST/16-19 CET 
Presenter: Mads Lausen Nielsen, PhD, Project Manager at Evaxion

Abstract title: Endogenous retrovirus-derived neoantigens enable a personalized cancer vaccine strategy for glioblastoma
Poster#: 6975
Session category: Immunology
Session title: Novel Models of Immunotherapy Response
Location: Poster section 8
Date/Time: April 22, 2026, at 9am-12pm CST/16-19 CET 
Presenter: Megan Benz, Duke University Medical Center

Contact information 
Evaxion A/S
Mads Kronborg
Vice President, Investor Relations & Communication
+45 53 54 82 96
mak@evaxion.ai

About Evaxion
Evaxion is a pioneering TechBio company based upon its proprietary, clinically validated and scalable AI platform, AI-Immunology™. The platform harnesses the power of artificial intelligence to decode the human immune system and develop novel vaccine candidates for cancer and infectious diseases.

With AI-Immunology™ we conduct rapid, efficient and high-quality target discovery, drug design and development. Our team of +40 experts covers the entire value chain from target discovery to clinical development

We have developed a clinical pipeline of both personalized and off-the-shelf cancer vaccine candidates as well as prophylactic vaccine candidates for infectious diseases. All our candidates address high unmet medical needs, reflecting our commitment to transforming patients’ lives by providing innovative and targeted treatment options.

For more information about Evaxion, AI-Immunology™ and our pipeline, please visit our website. 

Forward-looking statement 
This announcement contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The words “target,” “believe,” “expect,” “hope,” “aim,” “intend,” “may,” “might,” “anticipate,” “contemplate,” “continue,” “estimate,” “plan,” “potential,” “predict,” “project,” “will,” “can have,” “likely,” “should,” “would,” “could,” and other words and terms of similar meaning identify forward-looking statements. Actual results may differ materially from those indicated by such forward-looking statements as a result of various factors, including, but not limited to, risks related to: our financial condition and need for additional capital; our development work; cost and success of our product development activities and preclinical and clinical trials; commercializing any approved pharmaceutical product developed using our AI platform technology, including the rate and degree of market acceptance of our product candidates; our dependence on third parties including for conduct of clinical testing and product manufacture; our inability to enter into partnerships; government regulation; protection of our intellectual property rights; employee matters and managing growth; our ADSs and ordinary shares, the impact of international economic, political, legal, compliance, social and business factors, including inflation, and the effects on our business from other significant geopolitical and macro-economic events; and other uncertainties affecting our business operations and financial condition. For a further discussion of these risks, please refer to the risk factors included in our most recent Annual Report on Form 20-F and other filings with the US Securities and Exchange Commission (SEC), which are available at www.sec.gov. We do not assume any obligation to update any forward-looking statements except as required by law. 

FAQ

What did Evaxion (EVAX) announce in this Form 6-K?

Evaxion reported that two scientific abstracts were accepted for presentation at the AACR Annual Meeting 2026. The company will share new data on its personalized cancer vaccine EVX-01 and its AI-Immunology™ platform applied to glioblastoma, and will join an AACR partnering event.

What is Evaxion’s EVX-01 cancer vaccine mentioned for EVAX investors?

EVX-01 is a personalized cancer vaccine designed using Evaxion’s AI-Immunology™ platform for patients with advanced melanoma. It is being investigated in a phase 2 trial in combination with MSD’s anti-PD-1 therapy KEYTRUDA® (pembrolizumab), with each patient receiving a unique vaccine based on their biology.

What new data will Evaxion (EVAX) present on EVX-01 at AACR?

Evaxion will present new biomarker and immunogenicity data from the phase 2 trial of EVX-01 in advanced melanoma. The trial studies EVX-01 in combination with KEYTRUDA® and evaluates how personalized, AI-designed vaccines stimulate T-cell responses in patients receiving this immunotherapy regimen.

How is Evaxion’s AI-Immunology™ platform being used in glioblastoma research?

Evaxion’s AI-Immunology™ platform is being used to identify endogenous retrovirus-derived neoantigens for inclusion in personalized cancer vaccines targeting glioblastoma. The AACR abstract describes how these AI-selected targets may enable a tailored vaccine strategy for this aggressive brain cancer with limited current treatment options.

When and where will Evaxion (EVAX) present its AACR posters?

Both posters are scheduled for April 22, 2026, from 9am-12pm CST (16-19 CET) at the AACR Annual Meeting in San Diego. The EVX-01 abstract is poster 7741 in poster section 42, while the glioblastoma abstract is poster 6975 in poster section 8.

Will Evaxion (EVAX) engage in partnering activities at AACR 2026?

Yes. In addition to presenting scientific data, Evaxion plans to participate in the AACR Oncology Industry Partnering event. This aligns with its strategy to identify potential partners and opportunities for both business partnerships and scientific collaborations around its AI-Immunology™ vaccine platform.

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Evaxion AS

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