Henry Brem, M.D. joins Galectin Therapeutics (GALT) Board as independent director
Filing Impact
Filing Sentiment
Form Type
8-K
Rhea-AI Filing Summary
Galectin Therapeutics Inc. appointed Henry Brem, M.D. as an independent member of its Board of Directors, effective March 12, 2026. The company states he was not appointed under any arrangement with another person and has no related-party transactions requiring disclosure under Regulation S-K Item 404(a).
Dr. Brem is a renowned neurosurgeon-scientist and translational medicine leader, serving as the Henry Brem Professor of Neurosurgery at Johns Hopkins University and Co-Director of the Brain Cancer Program at the Sidney Kimmel Comprehensive Cancer Center. He helped develop image-guided neurosurgical techniques and localized drug delivery systems such as Gliadel wafers, has published more than 416 peer-reviewed papers, holds multiple patents, and has been continuously funded by the NIH for over four decades.
The Board believes his extensive medical, clinical development, and leadership background will support Galectin’s strategy as it advances its galectin-3 inhibitor belapectin for patients with MASH cirrhosis, portal hypertension, and certain cancers. He will receive compensation consistent with the company’s standard non-employee director program.
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 8-K
CURRENT REPORT
PURSUANT TO SECTION 13 OR 15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934
Date of Report (Date of earliest event reported): March 12, 2026
(Exact name of registrant as specified in its charter)
| (State or Other Jurisdiction of Incorporation) | (Commission File Number) | (IRS Employer Identification No.) |
(Address of principal executive office) (zip code)
Registrant’s telephone number, including area code: (678 )
620-3186
N/A
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):
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Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
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Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
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Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR
240.14d-2(b))
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Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) Securities registered
pursuant to Section 12(b) of the Act:
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Title of each class
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Trading Symbol
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Name of each exchange on which registered
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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this
chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company ☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any
new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
| Item 5.02. |
Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
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On March 12, 2026, the Board of Directors of Galectin Therapeutics Inc. (the “Company”) appointed Dr. Henry Brem to serve as a
member of the Board of Directors, effective immediately.
Dr. Brem was not appointed pursuant to any arrangement or understanding with any other person. There are no transactions
between Dr. Brem and the Company that would be reportable under Item 404(a) of Regulation S-K. At the time of his appointment, Dr. Brem will not serve on any committees of the Board of Directors.
Dr. Brem will receive compensation for his service on the Board in accordance with the Company’s standard non-employee director
compensation program, which is described in the Company’s most recent proxy statement filed with the Securities and Exchange Commission.
Dr. Henry Brem, a director since 2026, is an internationally recognized neurosurgeon-scientist and leader in translational
medicine. He serves as the Henry Brem Professor of Neurosurgery at Johns Hopkins University and previously served from 2000 until 2025 as Director of the Department of Neurosurgery and Neurosurgeon-in-Chief at The Johns Hopkins Medical
Institutions. He is also Co-Director of the Brain Cancer Program at the Sidney Kimmel Comprehensive Cancer Center. Dr. Brem has helped transform neurosurgical oncology through the development of image-guided surgical techniques and localized drug
delivery systems, including Gliadel® wafers for brain tumors. He has published more than 416 peer-reviewed papers, holds multiple patents, and has been continuously funded by the NIH for over four decades. He is a member of the National Academy of
Medicine and has received numerous honors recognizing his contributions to clinical excellence and translational research. Dr. Brem has served as director for multiple private and public companies. The Board believes that Dr. Brem’s extensive
medical, management, director, and leadership experience make him highly qualified to serve as a member of our Board.
| Item 9.01 |
Financial Statements and Exhibits.
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(d) Exhibits.
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Exhibit No.
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Description
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99.1
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Press Release dated March 17, 2026
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104
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Cover Page Interactive Data File (embedded within the Inline XBRL document)
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SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, Galectin Therapeutics Inc. has duly caused this report to be
signed on its behalf by the undersigned hereunto duly authorized.
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GALECTIN THERAPEUTICS INC.
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Date: March 17, 2026
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By:
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/s/ Jack W. Callicutt |
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Jack W. Callicutt
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Chief Financial Officer
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Exhibit 99.1
Galectin Therapeutics Strengthens Board of Directors with Appointment of Henry Brem, M.D.
NORCROSS, Ga., March 17, 2026 (GLOBE NEWSWIRE) -- Galectin Therapeutics
Inc. (NASDAQ:GALT), the leading developer of galectin-3-targeted therapeutics for patients with MASH cirrhosis and portal hypertension, today announced it has appointed Henry Brem, M.D., as an independent director to its Board of
Directors.
Dr. Brem is an internationally recognized neurosurgeon-scientist and leader in translational medicine. He serves as the Henry Brem
Professor of Neurosurgery at Johns Hopkins University and previously served as Director of the Department of Neurosurgery and Neurosurgeon-in-Chief at The Johns Hopkins Medical Institutions. He is also Co-Director of the Brain Cancer Program at
the Sidney Kimmel Comprehensive Cancer Center.
“Dr. Brem is a pioneering physician-scientist whose career exemplifies the successful translation of innovative science into
meaningful therapies for patients,” said Richard E. Uihlein, Chairman of the Board of Directors of Galectin Therapeutics. “His deep experience leading complex clinical development programs and advancing novel therapeutic platforms through
regulatory approval will be invaluable as we advance belapectin for patients with MASH cirrhosis and portal hypertension.”
Dr. Brem has helped transform neurosurgical oncology through the development of image-guided surgical techniques and localized drug
delivery systems, including Gliadel® wafers for brain tumors. He has published more than 416 peer-reviewed papers, holds multiple patents, and has been continuously funded by the NIH for over four decades. He is a member of the National Academy
of Medicine and has received numerous honors recognizing his contributions to clinical excellence and translational research.
With the appointment of Dr. Brem, Galectin continues to strengthen its Board with leaders who bring deep scientific and clinical
expertise to support the Company’s strategic priorities and upcoming milestones.
About Galectin Therapeutics
Galectin Therapeutics is dedicated to developing novel therapies to improve the lives of patients with chronic liver disease and cancer.
Galectin’s lead drug belapectin is a carbohydrate-based drug that inhibits the galectin-3 protein, which is directly involved in multiple inflammatory, fibrotic, and malignant diseases, for which it has Fast Track designation by the U.S. Food and
Drug Administration. The lead development program is in metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis, or NASH) with
cirrhosis, the most advanced form of MASH-related fibrosis. Liver cirrhosis is one of the most pressing medical need and a significant drug development opportunity. Additional development programs are in treatment of combination immunotherapy for
advanced head and neck cancers and other malignancies. Advancement of these additional clinical programs is largely dependent on finding a suitable partner. Galectin seeks to leverage extensive scientific and development expertise as well as
established relationships with external sources to achieve cost-effective and efficient development. Additional information is available at www.galectintherapeutics.com.
Forward Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These
statements relate to future events or future financial performance, and use words such as “may,” “estimate,” “could,” “expect”, “look forward”, “believe”, “hope” and others. They are based on management’s current expectations and are subject to
factors and uncertainties that could cause actual results to differ materially from those described in the statements. These statements include those regarding the hope that Galectin’s development program for belapectin will lead to the first
therapy for the treatment of MASH, formerly known as NASH, with cirrhosis and those regarding the hope that our lead compounds will be successful in cancer immunotherapy and in other therapeutic indications. Factors that could cause actual
performance to differ materially from those discussed in the forward-looking statements include, among others, full analysis of the NAVIGATE trial data may not product positive data; Galectin may not be successful in developing effective treatments
and/or obtaining the requisite approvals for the use of belapectin or any of its other drugs in development; the Company may not be successful in scaling up manufacturing and meeting requirements related to chemistry, manufacturing and control
matters; the Company’s current clinical trial and any future clinical studies may not produce positive results in a timely fashion, if at all, and could require larger and longer trials, which would be time consuming and costly; plans regarding
development, approval and marketing of any of Galectin’s drugs are subject to change at any time based on the changing needs of the Company as determined by management and regulatory agencies; regardless of the results of any of its development
programs, Galectin may be unsuccessful in developing partnerships with other companies or raising additional capital that would allow it to further develop and/or fund any studies or trials. Galectin has incurred operating losses since inception,
and its ability to successfully develop and market drugs may be impacted by its ability to manage costs and finance continuing operations. For a discussion of additional factors impacting Galectin’s business, see the Company’s Annual Report on Form
10-K for the year ended December 31, 2024, and subsequent filings with the SEC. You should not place undue reliance on forward-looking statements. Although subsequent events may cause its views to change, management disclaims any obligation to
update forward-looking statements.
Company Contact:
Jack Callicutt, Chief Financial Officer
(678) 620-3186
ir@galectintherapeutics.com
Investors Relations Contacts:
Kevin Gardner
kgardner@lifesciadvisors.com
Galectin Therapeutics and its associated logo is a registered trademark of Galectin Therapeutics Inc. Belapectin is the USAN assigned
name for Galectin Therapeutics’ galectin-3 inhibitor belapectin.
FAQ
What did Galectin Therapeutics (GALT) announce in this 8-K filing?
Galectin Therapeutics announced the appointment of Henry Brem, M.D., as an independent director to its Board. The company highlights his extensive neurosurgical and translational medicine background as support for advancing its galectin-3 inhibitor belapectin in liver disease and oncology.
Who is Dr. Henry Brem, the new director at Galectin Therapeutics (GALT)?
Dr. Henry Brem is an internationally recognized neurosurgeon-scientist and translational medicine leader. He is the Henry Brem Professor of Neurosurgery at Johns Hopkins University, has over 416 peer-reviewed publications, multiple patents, and more than four decades of continuous NIH funding.
Why does Galectin Therapeutics believe Dr. Brem is qualified for its Board?
Galectin’s Board cites Dr. Brem’s extensive medical, management, director, and leadership experience as key qualifications. His work in complex clinical development and advancing novel therapies through regulatory approval aligns with Galectin’s focus on belapectin for MASH cirrhosis and cancer indications.
Will Dr. Henry Brem serve on any Galectin Therapeutics (GALT) Board committees?
At the time of his appointment, Dr. Brem will not serve on any Board committees. The company notes he joins as a Board member and will receive compensation under its standard non-employee director compensation program described in its most recent proxy.
Does Galectin Therapeutics disclose any related-party transactions with Dr. Brem?
The company states there are no transactions between Dr. Brem and Galectin Therapeutics that would be reportable under Item 404(a) of Regulation S-K. It also notes his appointment was not made under any arrangement or understanding with another person.
What is Galectin Therapeutics’ lead drug program mentioned with Dr. Brem’s appointment?
Galectin is developing belapectin, a carbohydrate-based galectin-3 inhibitor, as its lead drug. The lead program targets MASH cirrhosis with portal hypertension and holds FDA Fast Track designation, with additional development efforts in combination immunotherapy for certain head and neck cancers and other malignancies.
Filing Exhibits & Attachments
4 documents
Galectin Therapeutics Inc