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Geron swings to $1.4M Q3 profit as RYTELO sales rise

Geron kept RYTELO revenue guidance at the mid-to-high end of $220 million to $240 million and lowered operating-expense guidance to $220 million to $230 million.

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Sentiment and the balance of points

Rhea-AI Sentiment reads the wording of the document, how positive or negative its language is on a 1 to 5 scale. The balance of points shown with the takes weighs what the document actually discloses, so the two can disagree, for example when a trial that missed its main goal is described in upbeat language.

Form Type
8-K

Rhea-AI Filing Summary

Geron Corporation reported third-quarter 2026 results, with RYTELO net product revenue of $60.1 million, compared with $47.2 million in Q3 2025. Total revenue was $60.2 million. Net income was $1.4 million, versus a net loss of $18.4 million a year earlier; total costs and operating expenses were $54.4 million, compared with $61.1 million.

Cash, cash equivalents, restricted cash and marketable securities were approximately $339.4 million as of September 30, 2026, compared with $326.9 million as of June 30, 2026. Geron maintained 2026 RYTELO net product revenue guidance at the mid-to-high end of $220 million to $240 million and lowered total operating expense guidance to $220 million to $230 million from $230 million to $240 million.

Geron initiated a gated commercial launch in targeted European markets, with RYTELO availability in Germany expected by year-end. The company also stated that the Phase 3 IMpactMF trial was discontinued and it does not expect to pursue an approval pathway for relapsed/refractory myelofibrosis.

2 points · 0 major

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Rhea-AI gives every point it takes from this document a weight. Minor counts 1, Moderate 3 and Major 9, so one Major point outweighs several Minor ones. The bar adds up the weights on each side, and when neither side holds more than 65% of the total the balance reads Mixed.

It reads the document as published, with the same rules for every company, and it does not look at what the market expected or at how the stock traded, so a point can be objectively good on a day the stock falls.

Rhea-AI Sentiment measures something else, the tone of the wording.

0 major · 1 point

How the balance works

Positive

  • Moderate point$60.1 million in Q3 net product revenue, versus $47.2 million a year earlier.
  • Moderate point$1.4 million net income, compared with an $18.4 million net loss in Q3 2025.

Negative

  • Moderate pointThe Phase 3 IMpactMF trial was discontinued; Geron does not expect to pursue an approval pathway for relapsed/refractory myelofibrosis.
Item 2.02 Results of Operations and Financial Condition Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, or exhibit attachments filed with this report.
RYTELO net product revenue $60.1 million Q3 2026; $47.2 million in Q3 2025
Net income $1.4 million Q3 2026; net loss of $18.4 million in Q3 2025
Total costs and operating expenses $54.4 million Q3 2026; $61.1 million in Q3 2025
Cash, cash equivalents, restricted cash and marketable securities Approximately $339.4 million As of September 30, 2026
RYTELO net product revenue guidance Mid-to-high end of $220 million to $240 million Fiscal year 2026
Total operating expense guidance $220 million to $230 million Fiscal year 2026; lowered from $230 million to $240 million
gated commercial launch technical
"initiated a gated commercial launch to bring RYTELO to targeted EU markets"
telomerase inhibitor medical
"RYTELO (imetelstat) is an oligonucleotide telomerase inhibitor"
A telomerase inhibitor is a drug that blocks telomerase, an enzyme some cells use to keep protective caps on the ends of their chromosomes so they can keep dividing. Investors care because blocking this enzyme can slow or stop growth of certain cancers and affect drug development value, much like cutting off a plant’s water supply to stop it from spreading; success or failure in trials and regulatory approval can strongly affect a company’s future revenue and stock.
transfusion-dependent anemia medical
"treatment of adult patients with transfusion-dependent anemia"
A chronic condition in which a patient’s body cannot produce enough healthy red blood cells and therefore requires regular blood transfusions to survive or function. Think of it like a device that needs frequent battery recharges to keep running; the ongoing transfusion requirement drives steady demand for medical services, supplies, and potential drug or device treatments, making it a key factor in evaluating healthcare costs, market size, and clinical trial outcomes.
erythropoiesis-stimulating agents medical
"have not responded to or have lost response to ... erythropoiesis-stimulating agents"
Drugs that stimulate the body to produce more red blood cells, used to treat anemia from chronic illness or medical treatments. They matter to investors because approvals, safety findings, patent status and reimbursement rules directly affect sales, company valuations and healthcare costs—think of them as a factory upgrade that increases the supply of oxygen-carrying cells, where regulators and payers control how fast and widely that upgrade can be used.
RYTELO net product revenue $60.1 million Compared with $47.2 million in Q3 2025
Net income (loss) $1.4 million Compared with a net loss of $18.4 million in Q3 2025
Total costs and operating expenses $54.4 million Compared with $61.1 million in Q3 2025
Guidance

For fiscal year 2026, RYTELO net product revenue is expected at the mid-to-high end of $220 million to $240 million; total operating expenses are expected to be $220 million to $230 million, lowered from $230 million to $240 million.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How much RYTELO revenue did GERN report in Q3 2026?

Geron reported $60.1 million in RYTELO net product revenue for Q3 2026, compared with $47.2 million in Q3 2025. Total revenue was $60.2 million, including $76,000 in royalties.

What is GERN's 2026 revenue and operating expense guidance?

Geron expects RYTELO net product revenue at the mid-to-high end of $220 million to $240 million. It expects total operating expenses of $220 million to $230 million, lowered from its prior range of $230 million to $240 million.

When is RYTELO expected to become available in Germany?

RYTELO availability in Germany is expected by the end of the year as part of a gated commercial launch in targeted European markets.

How long does GERN expect its cash resources to fund operations?

Based on current operating plans and assumptions, Geron believes its existing cash, cash equivalents, restricted cash and marketable securities, together with anticipated net revenue from U.S. RYTELO sales, will fund projected operating requirements for the foreseeable future.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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GERON CORP false 0000886744 0000886744 2026-11-04 2026-11-04
 
 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 

 

FORM 8-K

 

 

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d)

OF THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported): November 4, 2026

 

 

GERON CORPORATION

(Exact name of registrant as specified in its charter)

 

 

 

Delaware   000-20859   75-2287752

(State or other jurisdiction

of incorporation)

 

(Commission

File Number)

 

(IRS Employer

Identification No.)

919 E. HILLSDALE BLVD., SUITE 250

FOSTER CITY, California 94404

(Address of principal executive offices, including zip code)

(650) 473-7700

(Registrant’s telephone number, including area code)

N/A

(Former name or former address, if changed since last report)

 

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

☐

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

☐

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

☐

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

☐

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

 

Title of each class

 

Trading
Symbol(s)

 

Name of each exchange
on which registered

Common Stock, $0.001 par value   GERN   The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

 

 
 


Item 2.02

Results of Operations and Financial Condition

On November 4, 2026, Geron Corporation (the “Company”) issued a press release announcing its financial results for the quarter ended September 30, 2026 and recent business highlights. A copy of the press release is attached as Exhibit 99.1.

The information contained in Item 2.02 and in the accompanying Exhibit 99.1 to this Current Report shall be deemed to be “furnished” and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended (the “Securities Act”), and shall not be incorporated by reference into any filing made by the Company with the U.S. Securities and Exchange Commission under the Securities Act or the Exchange Act, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

 

Item 9.01

Financial Statements and Exhibits.

(d) Exhibits.

 

Exhibit
No.
   Description
99.1    Press release titled “Geron Corporation Reports Third Quarter 2026 Financial Results and Recent Business Highlights,” dated November 4, 2026
104    Cover Page Interactive Data File (the cover page XBRL tags are embedded within the Inline XBRL document)


SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

      GERON CORPORATION
Date: November 4, 2026     By:  

/s/ Timothy Williams

    Name:   Timothy Williams
    Title:  

Executive Vice President,

Chief Legal Officer and Corporate Secretary

Exhibit 99.1

 

LOGO

Geron Corporation Reports Third Quarter 2026 Financial Results and Recent Business Highlights

Achieved $60.1 million in RYTELO® (imetelstat) net product revenue in Q3 2026, an increase of 5% compared to Q2 2026

Reiterated 2026 RYTELO net product revenue at the mid-to-high end of the $220 million to $240 million range; lowered 2026 total operating expenses range to $220 million to $230 million

Initiated gated commercial launch to expand RYTELO access to eligible LR-MDS patients in targeted European markets, with availability expected in Germany by end of year

Ended Q3 2026 with cash, cash equivalents, restricted cash, and marketable securities of $339 million

Company to host conference call and webcast today, November 4, 2026, at 8:00 a.m. ET

FOSTER CITY, Calif., November 4, 2026 (GLOBE NEWSWIRE) – Geron Corporation (Nasdaq: GERN), a hematology-focused commercial stage biopharmaceutical company pursuing more meaningful moments for people living with blood cancer, today reported financial results for the third quarter of 2026 and recent business highlights.

“Another quarter of strong RYTELO demand growth reinforces our confidence in the LR-MDS commercial opportunity and our ability to reach more second-line patients. Increased demand growth is being driven by the community practices which, in our view, indicates the potential for RYTELO to have a long growth runway in the U.S.,” said Harout Semerjian, President and Chief Executive Officer of Geron. “Outside the U.S. there is a clear opportunity for us to serve more patients and create additional value by broadening RYTELO’s access. As such, we have initiated a gated commercial launch to bring RYTELO to targeted EU markets with availability in Germany expected by the end of the year. Expanding access to therapies, along with pursing opportunistic innovation, is a key part of building a leading hematology company.”

Recent Business Highlights

 

  •  

Reported RYTELO net product revenue of $60.1 million in the third quarter of 2026.

 

  •  

Grew RYTELO demand by 10% in the third quarter 2026, compared to the second quarter 2026.

 

  •  

Increased ordering accounts by roughly 8% in the third quarter 2026 to approximately 1,700.

 

  •  

Initiated a gated commercial launch to bring RYTELO to eligible LR-MDS patients in targeted European markets. RYTELO is expected to be available in Germany later this year and France in 2027.

 

  •  

Exhibited three posters at the Society of Hematologic Oncology (SOHO) 2026 Annual Meeting, including real-world evidence of imetelstat for the treatment of LR-MDS that was generally consistent with the Phase 3 IMerge trial and an updated post-hoc analysis of the Phase 2 IMbark study of imetelstat for the treatment of relapsed/refractory myelofibrosis.1-3


  •  

Delivered an oral presentation of retrospective real-world evidence of imetelstat in LR-MDS consistent with the IMerge trial along with a poster featuring a post-hoc study from the IMerge trial at the 88th Annual Meeting of the Japanese Society of Hematology (JSH).4-5

 

  •  

Provided an oral presentation at the 2026 Annual Meeting of the German, Austrian and Swiss Societies for Hematology and Medical Oncology (DGHO, OeGHO, SGMO, SGH) highlighting post-hoc pooled analysis from the IMerge population that suggests transient cytopenias observed early in treatment may be the result of an on-target effect of imetelstat and may be predictive of a better therapeutic response in LR-MDS patients.6

 

  •  

Nominated for the 2026 Prix Galien USA Award for Best Product for Rare/Orphan Diseases for RYTELO in LR-MDS, an award recognizing extraordinary scientific achievements in transforming health and improving lives.

 

  •  

Published two manuscripts in peer-reviewed journals highlighting imetelstat’s role in LR-MDS and other hematological diseases:

 

  •  

“Overall Survival and Long-Term Outcomes from the Randomized, Double-Blind, Placebo-Controlled, Phase III IMerge Trial of Imetelstat for Lower-Risk Myelodysplastic Syndromes” in Haematologica.7

 

  •  

“Combining the Telomerase Inhibitor Imetelstat with the BCL-2 Inhibitor Venetoclax Enhances Apoptosis and Improves Survival in Acute Myeloid Leukemia Cellular and Animal Models” in the Journal of Clinical Medicine.8

 

  •  

Announced the discontinuation of the Phase 3 IMpactMF trial evaluating imetelstat in JAK inhibitor R/R myelofibrosis based on a recommendation from the independent Data Monitoring Committee (DMC) that the trial was unlikely to meet the primary endpoint of overall survival. There were no new safety signals observed in the trial that change the known safety profile of imetelstat.

Third Quarter 2026 Financial Results

Cash and Marketable Securities

As of September 30, 2026, Geron had approximately $339.4 million in cash, cash equivalents, restricted cash and marketable securities, compared to $326.9 million as of June 30, 2026, which provides the Company with cash to fund its operating requirements for the foreseeable future.

Net Income (Loss)

For the three months ended September 30, 2026, the Company reported a net income of $1.4 million, or $0.00 per share, compared to a net loss of $18.4 million, or $0.03 per share, for the three months ended September 30, 2025. The change in net income (loss) is primarily attributable to increased revenue and continued financial discipline lowering operating expenses across the company.

Revenues

Total product revenue, net for the three months ended September 30, 2026, was $60.1 million, compared to $47.2 million for the three months ended September 30, 2025.


Costs and Operating Expenses

Total costs and operating expenses for the three months ended September 30, 2026, were $54.4 million, compared to $61.1 million for the three months ended September 30, 2025. The decrease is primarily due to lower personnel-related and clinical development expenses, partially offset by non-cash inventory-related expenses.

Cost of goods sold was approximately $6.1 million for the three months ended September 30, 2026, compared to $1.0 million for the three months ended September 30, 2025, which consisted of costs to manufacture and distribute RYTELO. The increase is primarily due to non-cash inventory-related expenses.

Research and development expenses for the three months ended September 30, 2026, were $12.7 million, compared to $21.1 million for the same period in 2025. The decrease in research and development expenses was primarily a result of lower personnel-related expenses and lower clinical and chemistry, manufacturing, and controls (CMC) costs.

Selling, general and administrative expenses for the three months ended September 30, 2026, were $35.7 million, compared to $39.0 million for the same period in 2025. The decrease was primarily due to lower personnel-related expenses.

2026 Financial Guidance

For fiscal year 2026, the Company continues to expect RYTELO net product revenue to be at the mid-to-high end of the $220 million to $240 million range. Geron now expects total operating expenses to be between $220 million and $230 million, down from its prior guidance range of $230 million to $240 million. Total operating expenses include non-cash items such as stock-based compensation expense, amortization of debt discounts and issuance costs, depreciation, and amortization.

Based on current operating plans and assumptions, the Company believes that its existing cash, cash equivalents, restricted cash and marketable securities, together with anticipated net revenues from U.S. sales of RYTELO, will be sufficient to fund projected operating requirements for the foreseeable future.

Conference Call

Geron will host a conference call at 8:00 a.m. ET on Wednesday, November 4, 2026, to discuss business updates and third quarter 2026 financial results.

A live webcast of the conference call will be available through the Investors section of the Company’s website at www.geron.com. A replay of the webcast will be archived and available on the Company’s website.

 

1.

Data presented at the Society of Hematologic Oncology (SOHO) 2026 Annual Meeting: Thomas J, et al. “Early Real-World Use and Hematologic Outcomes With Imetelstat in Patients With Myelodysplastic Syndromes: Insights From a United States Community Oncology Chart Review.” Poster #MDS-775. September 9-12, 2026; Houston, TX, USA & Online

2.

Data presented at the Society of Hematologic Oncology (SOHO) 2026 Annual Meeting: Kuykendall AT, et al. “Updated Analysis of Overall Survival With Imetelstat in Relapsed or Refractory Myelofibrosis from IMbark Versus Real-World Data, and Assessment of Real-World Treatment Patterns: Updated Post Hoc Analysis With Extended Follow Up.” Poster #MPN-269. September 9-12, 2026; Houston, TX, USA & Online

3.

Data presented at the Society of Hematologic Oncology (SOHO) 2026 Annual Meeting: Mascarenhas JO, et al. “Correlation Between IL-8 and TNF-Alpha and Overall Survival in Imetelstat-Treated Patients With Myelofibrosis Relapsed or Refractory to a Janus-Associated Kinase Inhibitor in the IMbark Trial.” Poster #MPN-298. September 9-12, 2026; Houston, TX, USA & Online


4.

Data presented at the Annual Meeting of the Japanese Society of Hematology: Eid J, et al. “Real-World Experience With Imetelstat in Lower-Risk Myelodysplastic Syndromes: Insights From United States Claims Data.” Oral Presentation #O1-11C-4. October 9-11, 2026; Kyoto, Japan

5.

Data presented at the Annual Meeting of the Japanese Society of Hematology: Eid J, et al. “Durable Clinical Outcomes With Imetelstat in Korean Patients With Lower-Risk-Myelodysplastic Syndromes.” Poster #P3-12-5. October 9-11, 2026; Kyoto, Japan

6.

Data presented at the Annual Meeting of the German, Austrian and Swiss Societies for Hematology and Medical Oncology: Brauer D, et al. “Telomerase Inhibition With Imetelstat in Patients With Lower-Risk Myelodysplastic Syndromes: Integrating Molecular Findings, Cytopenias, and Clinical Outcomes.” Oral Presentation #V755. October 9-12, 2026; Vienna, Austria

7.

Santini V, Komrokji RS, Savona MR, et al. Overall survival and long-term outcomes from the randomized, double-blind, placebo-controlled, phase III IMerge trial of imetelstat for lower-risk myelodysplastic syndromes. Haematologica. 2026 Sep 3. doi: 10.3324/haematol.2026.301456. Epub ahead of print. PMID: 42687814.

8.

Huang F, Rusbuldt JJ, Luistro L, Colton H, Eid J. Combining the Telomerase Inhibitor Imetelstat with the BCL-2 Inhibitor Venetoclax Enhances Apoptosis and Improves Survival in Acute Myeloid Leukemia Cellular and Animal Models. J Clin Med. 2026 Sep 23;15(19):7399. doi: 10.3390/jcm15197399. PMID: 42881859; PMCID: PMC13665851.

About RYTELO (imetelstat)

RYTELO (imetelstat) is an oligonucleotide telomerase inhibitor approved in the U.S. for the treatment of adult patients with lower-risk myelodysplastic syndromes (LR-MDS) with transfusion-dependent anemia requiring four or more red blood cell units over eight weeks who have not responded to or have lost response to or are ineligible for erythropoiesis-stimulating agents (ESAs). It is indicated to be administered as an intravenous infusion over two hours every four weeks.

In addition, RYTELO is approved in the European Union as a monotherapy for the treatment of adult patients with transfusion-dependent anemia due to very low, low or intermediate risk myelodysplastic syndromes without an isolated deletion 5q cytogenetic (non-del 5q) abnormality and who had an unsatisfactory response to or are ineligible for erythropoietin-based therapy.

RYTELO is a first-in-class treatment that works by inhibiting telomerase enzymatic activity. Telomeres are protective caps at the end of chromosomes that naturally shorten each time a cell divides. In LR-MDS, abnormal bone marrow cells often express the enzyme telomerase, which rebuilds those telomeres, allowing for uncontrolled cell division. Developed and exclusively owned by Geron, RYTELO is the first and only telomerase inhibitor approved by the U.S. Food and Drug Administration and the European Commission.

Please see RYTELO (imetelstat) full Prescribing Information, including Medication Guide, available at https://pi.geron.com/products/US/pi/rytelo_pi.pdf.

About Geron Geron is a hematology-focused biopharmaceutical company pursuing more meaningful moments for people living with blood cancer. Because patients cannot wait, we approach our work with urgency, bringing together deep expertise in telomerase biology with patient perspectives and insights from clinical research and real-world care. Our medicine, RYTELO® (imetelstat), is approved in the United States and European Union for certain patients with lower-risk myelodysplastic syndromes (LR-MDS). Geron is a commercial-stage company with offices in Parsippany, New Jersey and Foster City, California. To learn more, visit www.geron.com or follow us on LinkedIn.

Use of Forward-Looking Statements

Except for the historical information contained herein, this press release contains forward-looking statements made pursuant to the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that such statements, include, without limitation, those regarding: (i) Geron’s 2026 financial guidance, including its expected full year 2026 RYTELO net product revenue


range and total operating expense range; (ii) Geron being positioned to build in the future on RYTELO demand and net revenue growth, including in 2027; (iii) Geron’s European lower-risk MDS commercial strategy for RYTELO, including its gated commercial launch in targeted European markets and the expected timing of commercial availability in such markets; (iv) Geron’s 2026 priorities, including remaining focused on growing RYTELO net revenue in the U.S., pursuing pathways to bring RYTELO to patients outside of the U.S., remaining financially disciplined, and evaluating opportunistic innovation; (v) the expected timing of initial data from investigator-sponsored and real-world evidence trials focusing on RYTELO’s mechanistic studies, combinations and sequencing, earlier-line use and new settings; (vi) the pooled analysis from the IMerge population that suggests treatment-emergent cytopenias may reflect on-target effects associated with meaningful clinical outcomes, including hemoglobin increases and transfusion independence in LR-MDS; (vii) Geron’s belief that its existing cash, cash equivalents, restricted cash and marketable securities, together with anticipated net revenues from U.S. sales of RYTELO, will be sufficient to fund projected operating requirements for the foreseeable future; and (viii) and other statements that are not historical facts, constitute forward-looking statements. These forward-looking statements involve risks and uncertainties that can cause actual results to differ materially from those in such forward-looking statements. These risks and uncertainties, include, without limitation, risks and uncertainties related to: (a) whether Geron is successful in commercializing RYTELO for the treatment of certain patients with lower-risk MDS with transfusion dependent anemia and achieves market acceptance across the breadth of the eligible patient segments in RYTELO’s approved indication; (b) whether the FDA, European Commission and other regulatory authorities will approve imetelstat for other indications with labeling claims that are necessary or desirable for the successful commercialization of RYTELO and without significant labeling restrictions or requirements in an approved label; (c) Geron’s plans to commercialize RYTELO outside of the U.S., including Geron’s lack of experience selling, marketing and commercializing an approved drug outside of the U.S., Geron’s reliance on third parties to execute its gated European commercial launch, and risks related to country-by-country pricing and reimbursement, distribution, supply chain and other operational requirements of operating outside of the U.S.; (d) Geron’s future opportunities and plans, including the uncertainty of future revenues, expenses and other financial performance and results, and the related risk that Geron may be unable to meet its 2026 financial guidance; (e) whether Geron overcomes potential delays and other adverse impacts that may be caused by enrollment, clinical, safety, efficacy, technical, scientific, intellectual property, manufacturing, supply chain, pricing, coverage and reimbursement, market penetration, regulatory, healthcare or geopolitical challenges in order to obtain and maintain the financial resources for and meet expected timelines and planned milestones; (f) whether regulatory authorities permit the further development of imetelstat on a timely basis, or at all, without any clinical holds; (g) whether any future safety or efficacy results of RYTELO treatment cause its benefit-risk profile to become unacceptable or negatively impact commercialization, regulatory approvals or clinical development; (h) whether imetelstat actually demonstrates disease-modifying activity in patients, including transfusion independence in LR-MDS, and the ability to target the malignant stem and progenitor cells of the underlying disease; (i) whether Geron meets its post-marketing requirements and commitments for RYTELO; (j) whether there are failures or delays in manufacturing or supplying sufficient quantities of RYTELO (imetelstat) or other clinical trial materials that negatively impact commercialization of RYTELO or the conduct and timing of clinical trials; (k) that the expected timing for initial data from investigator-sponsored and real-world evidence trials may be delayed, perhaps significantly; (l) the discontinuation of the Phase 3 IMpactMF trial, including that Geron does not expect to pursue an approval pathway for imetelstat in relapsed/refractory myelofibrosis, will not recover its investment in the trial, and is increasingly dependent on the success of RYTELO in lower-risk MDS; (m) whether Geron stays in compliance with and satisfies its obligations under its debt and synthetic royalty financing agreements; (n) whether Geron successfully manages the changes in its workforce and realizes expected operating expense savings and business efficiencies resulting from its completed strategic restructuring plan; and (o) as it relates to Geron’s belief


as to the sufficiency of its cash resources, if Geron does not generate net revenues from commercial sales of RYTELO at the levels it anticipates, if it experiences unforeseen events or chooses to make other investments in its business, or if its assumptions regarding its projected operating expenses are otherwise incorrect, Geron may require additional funding, which may not be available to Geron on commercially-reasonable terms or at all. Additional information on the above risks and uncertainties and additional risks, uncertainties and factors that could cause actual results to differ materially from those in the forward-looking statements are contained in Geron’s filings and periodic reports filed with the Securities and Exchange Commission under the heading “Risk Factors” and elsewhere in such filings and reports, including Geron’s annual report on Form 10-K for the year ended December 31, 2025, Geron’s quarterly reports on Form 10-Q for the quarters ended March 31, 2026 and June 30, 2026, and Geron’s upcoming quarterly report on Form 10-Q for the quarter ended September 30, 2026, and subsequent filings and reports by Geron. Undue reliance should not be placed on forward-looking statements, which speak only as of the date they are made, and the facts and assumptions underlying the forward-looking statements may change. Except as required by law, Geron disclaims any obligation to update these forward-looking statements to reflect future information, events, or circumstances.


GERON CORPORATION

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

 

     Three Months Ended
September 30,
    Nine Months Ended
September 30,
 
(in thousands, except per share data)    2026     2025     2026     2025  
     (Unaudited)     (Unaudited)     (Unaudited)     (Unaudited)  

Revenues:

        

Product revenue, net

   $ 60,114     $ 47,167     $ 169,358     $ 135,610  

Royalties

     76       60       149       256  
  

 

 

   

 

 

   

 

 

   

 

 

 

Total revenues

     60,190       47,227       169,507       135,866  
  

 

 

   

 

 

   

 

 

   

 

 

 

Costs and operating expenses:

        

Cost of goods sold

     6,051       1,043       16,983       3,439  

Research and development

     12,709       21,070       49,695       57,884  

Selling, general and administrative

     35,702       39,001       109,990       117,588  

Restructuring charges

     (71 )      —        (622 )      —   
  

 

 

   

 

 

   

 

 

   

 

 

 

Total costs and operating expenses

     54,391       61,114       176,046       178,911  
  

 

 

   

 

 

   

 

 

   

 

 

 

Income (loss) from operations

     5,799       (13,887 )      (6,539 )      (43,045 ) 

Interest income

     3,025       4,264       9,417       14,072  

Interest expense

     (7,207 )      (8,644 )      (21,500 )      (25,360 ) 

Other income (expense), net

     (267 )      (161 )      (350 )      (305 ) 
  

 

 

   

 

 

   

 

 

   

 

 

 

Net income (loss)

   $ 1,350     $ (18,428 )    $ (18,972 )    $ (54,638 ) 
  

 

 

   

 

 

   

 

 

   

 

 

 

Net income (loss) per share:

        

Basic

   $ 0.00     $ (0.03 )    $ (0.03 )    $ (0.08 ) 

Diluted

   $ 0.00     $ (0.03 )    $ (0.03 )    $ (0.08 ) 

Weighted-average common shares:

        

Basic

     672,293       667,102       670,799       666,397  

Diluted

     674,052       667,102       670,799       666,397  


GERON CORPORATION

CONDENSED CONSOLIDATED BALANCE SHEETS

 

     September 30,
2026
     December 31,
2025
 
(in thousands)    (Unaudited)      (Note 1)  

Current assets:

     

Cash, cash equivalents and restricted cash

   $ 71,071      $ 79,440  

Current marketable securities

     217,300        280,359  

Other current assets

     180,371        160,472  
  

 

 

    

 

 

 

Total current assets

     468,742        520,271  

Noncurrent marketable securities

     50,999        41,289  

Property and equipment, net

     1,106        884  

Deposits and other assets

     6,259        8,096  
  

 

 

    

 

 

 

Total assets

   $ 527,106      $ 570,540  
  

 

 

    

 

 

 

Current liabilities

   $ 74,248      $ 111,542  

Noncurrent liabilities

     226,163        233,126  

Stockholders’ equity

     226,695        225,872  
  

 

 

    

 

 

 

Total liabilities and stockholders’ equity

   $ 527,106      $ 570,540  
  

 

 

    

 

 

 

 

Note 1:

Derived from audited financial statements included in the Company’s annual report on Form 10-K for the year ended December 31, 2025.

Investors and Media

Dawn Schottlandt

Senior Vice President, Investor Relations and Corporate Affairs

dschottlandt@geron.com

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