STOCK TITAN

Guardant Health (GH) co-CEO sells 260K shares after option exercises

Filing Impact
(Very High)
Filing Sentiment
(Very Negative)
Form Type
4

Rhea-AI Filing Summary

Guardant Health, Inc. co-CEO AmirAli Talasaz reported a combination of stock option exercises and share sales tied to the Talasaz and Eskandari 2017 Family Trust. On June 26 and June 29, 2026, the trust sold an aggregate 260,000 shares of common stock in open-market transactions at weighted-average prices around $150–$153 per share, executed across multiple price ranges.

On the same dates, stock options to acquire a total of 254,832 shares of common stock were exercised at a $4.18 per-share exercise price, converting derivative awards into common shares. The common stock and options are reported as held directly or indirectly, with a significant portion attributed to the Talasaz and Eskandari 2017 Family Trust.

Positive

  • None.

Negative

  • None.

Insights

Co-CEO executes options and sells 260K Guardant shares, largely offset by exercised awards.

The filing shows AmirAli Talasaz, via the Talasaz and Eskandari 2017 Family Trust, combining option exercises and open-market sales. He exercised options for 254,832 common shares at an exercise price of $4.18, converting derivative compensation into equity.

Across June 26–29, 2026, the trust sold 260,000 common shares in open-market transactions at weighted-average prices around $150–$153 per share. With no remaining derivative positions disclosed in this filing, the transactions look like a routine liquidity and portfolio-management event rather than a directional shift, so the overall signal is neutral.

Insider Talasaz AmirAli
Role Co-Chief Executive Officer
Sold 260,000 shs ($39.31M)
Type Security Shares Price Value
Exercise Stock Option (Right to Buy) 143,028 $0.00 --
Exercise Common Stock 143,028 $4.18 $598K
Sale Common Stock 25,812 $150.5282 $3.89M
Sale Common Stock 70,513 $151.4659 $10.68M
Sale Common Stock 46,663 $152.2045 $7.10M
Sale Common Stock 40 $153.00 $6K
Exercise Stock Option (Right to Buy) 111,804 $0.00 --
Exercise Common Stock 111,804 $4.18 $467K
Sale Common Stock 64,037 $150.4886 $9.64M
Sale Common Stock 52,935 $151.1595 $8.00M
Holdings After Transaction: Stock Option (Right to Buy) — 28,997 shares (Direct, null); Common Stock — 2,024,364 shares (Indirect, Shares held by Talasaz and Eskandari 2017 Family Trust)
Footnotes (1)
  1. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $150.00 to $150.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $151.00 to $151.79. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $151.00 to $151.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $152.00 to $152.68. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range. The stock option vested in equal monthly installments over 48 months commencing on April 23, 2017.
Shares sold 260,000 shares Aggregate open-market sales of common stock on June 26–29, 2026
Sale price range $150.00–$152.68 per share Multiple weighted-average sale price ranges across reported trades
Options exercised 254,832 shares Total common shares underlying options exercised, per transaction summary
Option exercise price $4.18 per share Exercise or conversion price for stock options converted into common stock
Net share direction Net sell of 260,000 shares transactionSummary netBuySellShares and netBuySellDirection
Derivative transactions 2 derivative entries Stock Option (Right to Buy) exercises reported in Form 4
open-market sale financial
"transaction_action": "open-market sale""
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
Stock Option (Right to Buy) financial
""security_title": "Stock Option (Right to Buy)""
weighted average sales price financial
"Represents the weighted average sales price per share."
derivative security financial
"Exercise or conversion of derivative security"
A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.
indirect ownership financial
""ownership_type": "indirect""
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Learn about SEC filing dates
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Talasaz AmirAli

(Last)(First)(Middle)
3100 HANOVER STREET

(Street)
PALO ALTO CALIFORNIA 94304

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Guardant Health, Inc. [ GH ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Co-Chief Executive Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/26/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/26/2026M111,804A$4.181,998,308IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/26/2026S64,037D$150.4886(1)1,934,271IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/26/2026S52,935D$151.1595(2)1,881,336IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/29/2026M143,028A$4.182,024,364IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/29/2026S25,812D$150.5282(1)1,998,552IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/29/2026S70,513D$151.4659(3)1,928,039IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/29/2026S46,663D$152.2045(4)1,881,376IShares held by Talasaz and Eskandari 2017 Family Trust
Common Stock06/29/2026S40D$1531,881,336IShares held by Talasaz and Eskandari 2017 Family Trust
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$4.1806/26/2026M111,804 (5)07/14/2027Common Stock111,804$0172,025D
Stock Option (Right to Buy)$4.1806/29/2026M143,028 (5)07/14/2027Common Stock143,028$028,997D
Explanation of Responses:
1. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $150.00 to $150.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.
2. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $151.00 to $151.79. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.
3. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $151.00 to $151.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.
4. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $152.00 to $152.68. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.
5. The stock option vested in equal monthly installments over 48 months commencing on April 23, 2017.
Remarks:
/s/ John G. Saia, as attorney-in-fact for AmirAli Talasaz06/30/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did Guardant Health (GH) report for AmirAli Talasaz?

Guardant Health reported that co-CEO AmirAli Talasaz, through the Talasaz and Eskandari 2017 Family Trust, sold 260,000 shares of common stock and exercised options for 254,832 shares at a $4.18 exercise price across June 26–29, 2026.

How many Guardant Health shares did the co-CEO sell in this Form 4?

The Form 4 shows open-market sales totaling 260,000 Guardant Health common shares. These trades occurred on June 26 and June 29, 2026, at weighted-average prices generally around $150–$153 per share, executed in multiple transactions within specified price ranges.

What stock options did AmirAli Talasaz exercise in Guardant Health (GH)?

The filing shows exercises of stock options covering 254,832 Guardant Health common shares at a $4.18 per-share exercise price. These options, described as Stock Option (Right to Buy), had previously vested in monthly installments over 48 months starting April 23, 2017.

Were the Guardant Health insider transactions direct or through a trust?

Most common stock transactions are reported as indirect, held by the Talasaz and Eskandari 2017 Family Trust. The derivative option positions are reported as directly owned. The Form 4 attributes the open-market sales of 260,000 shares to this family trust structure associated with AmirAli Talasaz.

What prices were Guardant Health shares sold at in these insider trades?

The reported sales used weighted-average prices per share. Transactions occurred in multiple trades within ranges, including $150.00–$150.99, $151.00–$151.79, $151.00–$151.99, and $152.00–$152.68, resulting in average sale prices generally around $150–$153 per Guardant Health share.