Guardant Health (NASDAQ: GH) CTO discloses stock sales and 68,144-share trust transfer

Rhea-AI Filing Summary

Guardant Health, Inc. reported insider equity transactions by its Chief Technology Officer, Darya Chudova, on Form 4. On 12/08/2025, 68,144 shares of common stock were transferred at no cost from her direct ownership to the Chudova Family Trust, changing the form of ownership from direct to indirect. The filing also shows two open-market sales of Guardant Health common stock on the same date: 9,271 shares sold at a weighted average price of $106.0029 per share and 13,664 shares sold at a weighted average price of $105.0371 per share, executed in multiple transactions within narrow price ranges.

After these transactions, Chudova reported beneficial ownership of 21,734 shares held directly and 54,480 shares held indirectly through the Chudova Family Trust. The disclosure notes that 488 of the shares in Table I were previously acquired under Guardant Health's Employee Stock Purchase Plan.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Chudova Darya

(Last) (First) (Middle)

3100 HANOVER STREET

(Street)

PALO ALTO CA 94304

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Guardant Health, Inc. [ GH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Technology Officer

3. Date of Earliest Transaction (Month/Day/Year)
12/08/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	12/08/2025		J	V	68,144(1)	D	$0	21,734	D
Common Stock	12/08/2025		J	V	68,144	A	$0	68,144	I	Chudova Family Trust
Common Stock	12/08/2025		S		9,271	D	$106.0029(2)	12,463	D
Common Stock	12/08/2025		S		13,664	D	$105.0371(3)	54,480	I	Chudova Family Trust

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Reflects changes in form of ownership from direct to indirect due to transfer of shares to The Chudova Family Trust.

2. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $106.00 to $106.11. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

3. Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $105.00 to $105.24. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Remarks:

Table I includes 488 shares acquired under the Guardant Health's Employee Stock Purchase Plan on 5/14/2023.

	/s/ John G. Saia, as attorney-in-fact for Darya Chudova	12/10/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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FAQ

What insider transaction did Guardant Health (GH) report for its CTO?

The Chief Technology Officer, Darya Chudova, reported a transfer of 68,144 Guardant Health common shares from direct ownership to the Chudova Family Trust, as well as open-market sales of additional shares, all dated 12/08/2025.

How many Guardant Health (GH) shares did the CTO sell on 12/08/2025?

The Form 4 shows two sales on 12/08/2025: one for 9,271 shares at a weighted average price of $106.0029 per share and another for 13,664 shares at a weighted average price of $105.0371 per share.

What is the CTO’s Guardant Health (GH) ownership after the reported transactions?

Following the reported transactions, Darya Chudova reported owning 21,734 Guardant Health common shares directly and 54,480 shares indirectly through the Chudova Family Trust.

What does the transfer of 68,144 Guardant Health (GH) shares represent?

The transfer of 68,144 shares reflects a change in form of ownership from direct to indirect, moving the shares into the Chudova Family Trust at a reported price of $0.

Were the Guardant Health (GH) share sales executed at a single price?

No. The filing states that the reported prices of $106.0029 and $105.0371 are weighted average prices, with actual sales occurring in multiple transactions within price ranges of $106.00–$106.11 and $105.00–$105.24, respectively.

Does the Guardant Health (GH) Form 4 mention shares from the Employee Stock Purchase Plan?

Yes. The remarks state that Table I includes 488 shares acquired under Guardant Health's Employee Stock Purchase Plan on 05/14/2023.