T. Rowe Price holds 5.4% of Guardant Health (NYSE: GH)

Rhea-AI Filing Summary

Guardant Health Inc. ownership filing by T. Rowe Price Associates, Inc. reports beneficial ownership of 7,035,771 shares of Common Stock, representing 5.4% of the class as of 03/31/2026. The filing lists sole voting power for 6,842,514 shares and sole dispositive power for 7,035,771 shares. The filing is signed by Ellen York, Vice President, on 05/15/2026.

Insights

Institutional Ownership Analyst

T. Rowe Price discloses a 5.4% stake in Guardant Health as of 03/31/2026.

The filing shows 7,035,771 shares beneficially owned with full dispositive control reported. This level of passive ownership is typical for large asset managers reporting under Schedule 13G when ownership is non‑activist.

Monitor subsequent filings for any change in percentage, voting power, or a move to Schedule 13D if activist intent emerges; timing of any such change would be disclosed in follow‑up SEC reports.

Key Figures

Beneficially owned: 7,035,771 shares Percent of class: 5.4% Sole voting power: 6,842,514 shares +3 more

6 metrics

Beneficially owned 7,035,771 shares as of 03/31/2026

Percent of class 5.4% ownership percentage reported on the filing

Sole voting power 6,842,514 shares number of shares with sole power to vote

Sole dispositive power 7,035,771 shares number of shares with sole power to dispose

CUSIP 40131M109 identifier for Guardant Health common stock

Signature date 05/15/2026 date the filing was signed by Ellen York

Key Terms

Schedule 13G, beneficially owned, sole dispositive power, CUSIP

4 terms

Schedule 13G regulatory

"T. Rowe Price Associates, Inc. filing type shown as Schedule 13G"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

beneficially owned financial

"Amount beneficially owned: 7035771"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

sole dispositive power regulatory

"Sole power to dispose or to direct the disposition of: 7035771"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

CUSIP technical

"CUSIP Number(s): 40131M109"

A CUSIP is a nine-character alphanumeric code that uniquely identifies a U.S. or Canadian financial security—such as a stock, bond, or fund share—like a Social Security number for an investment. It matters to investors because brokers, exchanges and record-keepers use the CUSIP to match trades, track ownership, settle transactions and pull accurate records, reducing errors and ensuring money and securities go to the right place.

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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

GUARDANT HEALTH INC

(Name of Issuer)

COMMON STOCK

(Title of Class of Securities)

40131M109

(CUSIP Number)

03/31/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 40131M109

1

Names of Reporting Persons

T. Rowe Price Associates, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

MARYLAND

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 6,842,514.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 7,035,771.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

7,035,771.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.4 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

Item 1.
(a)	Name of issuer: GUARDANT HEALTH INC
(b)	Address of issuer's principal executive offices: 3100 HANOVER STREET, PALO ALTO, CA, 94304
Item 2.
(a)	Name of person filing: T. Rowe Price Associates, Inc.
(b)	Address or principal business office or, if none, residence: 1307 Point Street, Baltimore, MD 21231
(c)	Citizenship: Maryland
(d)	Title of class of securities: COMMON STOCK
(e)	CUSIP Number(s): 40131M109
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 7035771
(b)	Percent of class: 5.4 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 6842514
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 7035771
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. T. Rowe Price Associates, Inc. hereby declares and affirms that the filing of Schedule 13G shall not be construed as an admission that Price Associates is the beneficial owner of the securities referred to, which beneficial ownership is expressly denied.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

T. Rowe Price Associates, Inc.

Signature:	Ellen York
Name/Title:	Vice President
Date:	05/15/2026

FAQ

What stake does T. Rowe Price hold in Guardant Health (GH)?

T. Rowe Price beneficially owns 7,035,771 shares, equal to 5.4% of Guardant Health's Common Stock as of 03/31/2026. The filing shows sole dispositive power over all 7,035,771 shares.

Who has voting power for the shares reported by T. Rowe Price?

The filing reports sole voting power for 6,842,514 shares and shared voting power of 0. Voting control figures are disclosed in the Schedule 13G ownership table.

When was the Schedule 13G signed and by whom?

The Schedule 13G is signed by Ellen York, Vice President of T. Rowe Price Associates, Inc., with the signature date shown as 05/15/2026 on the excerpt provided.

Does this filing indicate activist intent by T. Rowe Price?

This Schedule 13G reports passive ownership and does not state activist intent. Any change to activist intentions would typically require a different filing, such as a Schedule 13D, disclosed separately.

What identifying information about the shares is included in the filing?

The filing specifies the security as Common Stock with CUSIP 40131M109 and lists the issuer's principal executive office address in Palo Alto, CA.