Welcome to our dedicated page for Genprex SEC filings (Ticker: GNPX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Genprex, Inc. (NASDAQ: GNPX) SEC filings page on Stock Titan provides direct access to the company’s official U.S. Securities and Exchange Commission disclosures, along with AI-assisted context. As a clinical-stage gene therapy company, Genprex uses these filings to describe its oncology and diabetes pipelines, financing activities, and Nasdaq listing status.
Key documents include registration statements such as Form S-1 and Form S-3, where Genprex outlines its business overview, risk factors, and details of equity offerings and warrant structures. These filings describe the company’s focus on Reqorsa Gene Therapy (quaratusugene ozeplasmid) for non-small cell and small cell lung cancer, the Oncoprex Delivery System, and the GPX-002 diabetes gene therapy program using AAV delivery of Pdx1 and MafA genes to the pancreas.
Investors can also review Form 8-K current reports that document material events. Recent 8-Ks discuss registered direct offerings and concurrent private placements, at-the-market program updates, new patents and patent intentions around Reqorsa combinations with PD-1 and PD-L1 antibodies, additions of clinical trial sites for Acclaim-1 and Acclaim-3, and communications with Nasdaq regarding minimum bid price and stockholders’ equity requirements.
On Stock Titan, AI-powered tools summarize lengthy prospectuses and current reports, helping readers quickly identify sections related to gene therapy mechanisms, clinical trial design, regulatory designations, and capital-raising terms. As new filings appear on EDGAR, they are reflected here in near real time, giving users an organized view of Genprex’s regulatory history, financing transactions, and disclosures relevant to GNPX stock.
Genprex, Inc. is conducting a primary offering of 243,622 shares of common stock at $11.21 per share, for gross proceeds of $2,731,002.62. After placement agent fees and estimated offering expenses, the company expects net proceeds of approximately $2.3 million. The offering is being executed on a reasonable best‑efforts basis by H.C. Wainwright & Co.
In a concurrent private placement, purchasers will receive unregistered warrants to buy up to 487,244 shares at an $11.00 exercise price. Shares outstanding were 1,004,437 before the transaction and are expected to be 1,248,059 after the offering. Genprex recently effected 1‑for‑50 and 1‑for‑40 reverse stock splits and has an active Nasdaq compliance plan. The company plans to use proceeds for working capital and general corporate purposes.
Genprex reported that its research collaborators will present positive preclinical data on REQORSA (quaratusugene ozeplasmid) for ALK-EML4 positive non-small cell lung cancer at the 2025 AACR-NCI-EORTC conference in Boston. The studies showed that REQORSA increased TUSC2 expression and activated apoptotic pathways across ALK+ cell lines and patient-derived organoids, including models with acquired resistance to the ALK inhibitor alectinib.
In a mouse model, alectinib alone shrank tumors by 60%, while REQORSA alone and the REQORSA–alectinib combination each shrank tumors by 79%. Researchers also observed slower tumor regrowth after combined treatment versus single agents and increased markers of apoptosis (including caspase 3/7 activity). The abstract concludes that these in vitro and in vivo findings support a potential clinical trial of REQORSA in ALK-EML4 positive NSCLC.
Genprex, Inc. (GNPX) effected a one-for-fifty reverse stock split of its common stock, effective at 12:01 a.m. on October 21, 2025. The action consolidates every 50 pre-split shares into 1 share.
After giving effect to the reverse split, the company reports 1,004,326 shares outstanding as of October 21, 2025, prior to any rounding of fractional shares. The filing lists no other corporate changes or transactions related to this event.
Genprex received a Nasdaq Hearings Panel exception to regain compliance with the $1.00 Minimum Bid Price and minimum stockholders’ equity listing standards through October 31, 2025, with Panel discretion to extend to February 9, 2026. The Panel may reconsider the exception, and no further extension is assured.
To support compliance, the Board approved a 1-for-50 reverse stock split effective at 12:01 a.m. ET on October 21, 2025. Trading will begin on a split-adjusted basis that day under ticker GNPX; fractional shares will be rounded up to the next whole share. Par value and authorized shares are unchanged, and outstanding options and warrants will be adjusted per their terms.
Clinical updates: Acclaim-1 (NSCLC) Phase 2a targets ~33 patients with an interim analysis after the first 19; enrollment of those 19 is expected in the first half of 2026 with interim analysis in the second half of 2026 (FDA Fast Track). Acclaim-3 (ES‑SCLC) Phase 2 plans ~50 patients across ~10–15 U.S. sites, with a futility look after the 25th patient reaches 18 weeks; the same first‑half/second‑half 2026 timing is expected (FDA Fast Track and Orphan Drug).
Genprex, Inc. reports that Nasdaq has notified the company it is not in compliance with key listing standards, creating a risk of delisting from the Nasdaq Capital Market. Nasdaq’s Listing Qualifications Staff cited stockholders’ equity of $1,391,195 as of June 30, 2025, which is below the required $2.5 million minimum, and noted the company also does not meet alternative market value or net income standards.
The notice follows an earlier determination to delist Genprex for failing to meet the $1.00 per share minimum bid price requirement within a 180-day grace period and not qualifying for an additional extension due to not meeting Nasdaq’s $5,000,000 initial listing equity threshold. Genprex has requested a hearing before a Nasdaq Hearings Panel, which temporarily stays suspension or delisting while it presents a plan to regain compliance, but the company cautions there is no assurance the panel will grant continued listing.
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