[Form 4] GRAIL, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Joshua J. Ofman, identified as an officer (President) of GRAIL, Inc. (ticker GRAL), reported a sale of common stock on 08/19/2025. The Form 4 shows a transaction code S for the sale of 4,202 shares at a broker-calculated weighted average price of $32.02. After the sale, Ofman beneficially owned 487,874 shares on a direct basis. The filer notes the shares were sold as part of a block trade executed in multiple transactions and offers to provide detailed per-trade pricing on request. The form was signed by an attorney-in-fact on 08/20/2025.

Positive

• None.

Negative

• Insider sale of 4,202 shares by the company's President could be interpreted negatively by some investors despite being a relatively small portion of holdings

Insights

Securities Analyst

TL;DR: A routine insider sale of 4,202 shares at $32.02 leaves the officer with substantial remaining ownership.

The reported transaction is a sale (code S) of 4,202 shares executed as part of a block trade at a weighted average price of $32.02. The post-transaction direct beneficial ownership of 487,874 shares remains sizeable and suggests continued alignment with shareholders. The filer’s explanation about weighted-average pricing is standard for block trades and indicates multiple execution prices; the filer offers to disclose per-trade details if requested. This Form 4 contains no indication of derivative exercises, option grants, or other compensatory transactions.

Corporate Governance Expert

TL;DR: Disclosure reflects a typical insider liquidity event; documentation and offer to provide pricing detail are appropriate.

The filing documents an officer-level sale by the President of GRAIL and includes the customary explanatory remark about broker-calculated weighted-average pricing for a multi-leg block trade. The prompt filing and attorney-in-fact signature meet disclosure protocol. No governance issues, such as large percentage ownership changes or unexplained transfers, are present in the report.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Ofman Joshua J.

(Last) (First) (Middle)

C/O GRAIL, INC.

1525 O'BRIEN DRIVE

(Street)

MENLO PARK CA 94025

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
GRAIL, Inc. [ GRAL ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President

3. Date of Earliest Transaction (Month/Day/Year)
08/19/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/19/2025		S		4,202(1)	D	$32.02	487,874	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The price reported in Column 4 is a weighted average price calculated by the broker executing the sell-to-cover transactions. These shares were sold as part of a block trade in multiple transactions, and the Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price.

Remarks:

	/s/Donald Lang, as Attorney-in-Fact for Joshua Ofman	08/20/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did the GRAIL (GRAL) Form 4 filed by Joshua Ofman report?

The Form 4 reported a sale of 4,202 common shares on 08/19/2025 at a weighted average price of $32.02.

How many GRAIL shares does Joshua Ofman own after the reported sale?

After the sale, Joshua Ofman beneficially owned 487,874 shares on a direct basis.

What does the transaction code 'S' mean on the Form 4?

Transaction code S indicates a sale of securities; here it denotes the sale of 4,202 GRAIL common shares.

Was the sale executed at a single price?

No. The filer states the reported price is a broker-calculated weighted average for a block trade executed in multiple transactions and offers to provide per-trade pricing on request.

When was the Form 4 signed and who signed it?

The form shows a signature by Donald Lang acting as attorney-in-fact for Joshua Ofman on 08/20/2025.