GUTS Special Meeting Oct 3: $23M potential from Tranche B warrants at $1.05
Fractyl Health (GUTS) is soliciting proxies for a virtual Special Meeting of stockholders to be held on October 3, 2025, for holders of record as of August 6, 2025. At the record date there were 50,289,014 shares outstanding. The meeting will be conducted via webcast and only holders with a 16-digit control number may participate online.
The key proposal seeks stockholder approval related to the issuance of shares underlying the Tranche B Warrants, each with an initial exercise price of $1.05. If all Tranche B Warrants are cash exercised, the company would receive approximately $23.0 million and 21,904,761 additional shares would be issued, diluting existing holders. The company entered a voting agreement with directors, officers and Mithril (holding ~21% voting power) to vote in favor of the proposal. The filing discloses risks if the warrants are not exercisable and notes ongoing repeated stockholder approval requests until approved.
Positive
- Potential gross proceeds of approximately $23.0 million if all Tranche B Warrants are cash exercised, providing near-term funding.
- Voting agreement with directors, officers and Mithril (representing ~21% voting power) increases likelihood the proposal will pass.
Negative
- Significant dilution: full exercise would issue 21,904,761 shares against 50,289,014 outstanding, materially reducing existing ownership percentages.
- Funding uncertainty: if Tranche B Warrants cannot be exercised, the company will not receive the $23.0 million, which could adversely affect operations and clinical development.
- Administrative and distraction costs: the company must seek stockholder approval every 30 days until approval, increasing expenses and diverting management time.
Insights
TL;DR: Proposal centralizes financing authority but raises dilution and governance concerns given repeated proxy solicitations and affiliated support.
The proposal authorizes issuance tied to Tranche B Warrants that could dilute existing shareholders materially (21,904,761 potential shares). A voting agreement with Mithril and company insiders, representing ~21% voting power, signals management-aligned support but concentrates influence and may limit independent deliberation by other holders. Repeated 30-day approval solicitations impose administrative burden and potential shareholder fatigue, which can affect governance transparency and minority holder influence.
TL;DR: The financing could provide near-term cash (~$23.0M) but risks long-term dilution and operational distraction if approval is delayed.
If fully exercised, Tranche B Warrants would deliver approximately $23.0 million of gross proceeds, which could support operations and clinical programs. However, issuance of up to 21.9 million shares represents a significant increase versus 50.3 million outstanding shares, diluting EPS and ownership. The filing also warns that failure to obtain approval may hinder future capital access and divert management attention to repeated votes, creating execution risk.
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Filed by the Registrant ☒ | Filed by a Party other than the Registrant ☐ | ||
☒ | Preliminary Proxy Statement |
☐ | Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) |
☐ | Definitive Proxy Statement |
☐ | Definitive Additional Materials |
☐ | Soliciting Material under §240.14a-12 |

☒ | No fee required. |
☐ | Fee paid previously with preliminary materials. |
☐ | Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11. |
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1 | The approval of the issuance of shares of the Company’s common stock in accordance with Nasdaq Listing Rule 5635(d) and Nasdaq’s interpretations and guidance thereunder pursuant to the exercise of warrants sold in our financing transaction that closed on August 7, 2025 (the “Offering”). | ||
2 | The approval of an adjournment of the Special Meeting, if necessary, to solicit additional proxies if there are not sufficient votes at the time of the Special Meeting to approve Proposal No. 1. | ||
By Order of the Board of Directors, | |||
[ ] | |||
Sarah Toomey | |||
General Counsel and Corporate Secretary | |||
[ ], 2025 | |||
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Page | |||
EXECUTIVE SUMMARY | 1 | ||
PROPOSAL ONE – APPROVAL OF THE ISSUANCE OF THE COMPANY’S COMMON STOCK UPON THE EXERCISE OF WARRANTS IN ACCORDANCE WITH NASDAQ LISTING RULE 5635(D) | 3 | ||
PROPOSAL TWO – APPROVAL OF AN ADJOURNMENT OF THE SPECIAL MEETING. | 5 | ||
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT | 6 | ||
QUESTIONS AND ANSWERS ABOUT THE SPECIAL MEETING OF STOCKHOLDERS | 9 | ||
ADDITIONAL INFORMATION | 13 | ||
FORWARD-LOOKING STATEMENTS | 15 | ||
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• | By Internet: Visit the website listed on your proxy card |
• | By Phone: Call the telephone number on your proxy card |
• | By Mail: If you received paper copies, sign, date and return your proxy card in the provided envelope |
• | Participate in the Special Meeting webcast using your 16-digit control number |
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Proposal | Page Number | Voting Standard | Board Vote Recommendation | ||||||||
Proposal No. 1: Approval of the issuance of shares of the Company’s common stock in accordance with Nasdaq Listing Rule 5635(d) and Nasdaq’s interpretations and guidance thereunder pursuant to the exercise of warrants sold in our financing transaction that closed on August 7, 2025 (the “Offering”). | 3 | Affirmative vote of the holders of a majority in voting power of the votes cast on the matter | FOR | ||||||||
Proposal No. 2: Approval of an adjournment of the Special Meeting, if necessary, to solicit additional proxies if there are not sufficient votes at the time of the Special Meeting to approve Proposal No. 1. | 5 | Affirmative vote of the holders of a majority in voting power of the votes cast on the matter | FOR | ||||||||
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• | Each of the Tranche B Warrants has an initial exercise price of $1.05 per share. If all the Tranche B Warrants are cash exercised we will receive additional gross proceeds of approximately $23.0 million. If the Tranche B Warrants cannot be exercised, we will not receive such proceeds, which could adversely impact our business and financial condition, including our ability to fund our operations and advance the clinical trials and related product development activities for our product candidates. |
• | In connection with the Offering and the issuance of the Tranche B Warrants, we agreed to seek stockholder approval every thirty (30) days until our stockholders approve the issuance of the shares of common stock underlying the Tranche B Warrants. The costs and expenses associated with repeatedly seeking such approval could adversely impact our ability to fund our operations. Additionally, management may devote substantial time and attention to seeking the Tranche B Warrant Stockholder Approval, which would distract management from operating our business. |
• | Failure to obtain the Tranche B Warrant Stockholder Approval may discourage future investors from engaging in financings with us. As a result, we may have difficulty finding alternative sources of capital to fund our operations in the future on terms favorable to us or at all. |
✔ | The Board recommends a vote “FOR” the approval of the issuance of shares of the Company’s common stock in accordance with Nasdaq Listing Rule 5635(d) and Nasdaq’s interpretations and guidance thereunder pursuant to the exercise of warrants sold in the Offering. | ||
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✔ | The Board recommends a vote “FOR” the approval of an adjournment of the Special Meeting, if necessary, to solicit additional proxies if there are not sufficient votes at the time of the Special Meeting to approve Proposal No. 1. | ||
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• | each person, or group of affiliated persons, known by us to beneficially own more than 5% of our outstanding shares of common stock; |
• | each of our named executive officers; |
• | each of our directors; and |
• | all of our executive officers and directors as a group. |
Shares Beneficially Owned | ||||||
Name of Beneficial Owner | Number | Percentage | ||||
5% or Greater Stockholders | ||||||
Entities affiliated with Mithril(1) | 6,412,201 | 12.8% | ||||
CVF, LLC(2) | 5,544,669 | 10.8% | ||||
Entities affiliated with Maverick Capital(3) | 5,119,290 | 10.0% | ||||
Entities affiliated with General Catalyst(4) | 4,884,186 | 9.7% | ||||
Entities affiliated with Bessemer Venture Partners(5) | 4,770,901 | 9.5% | ||||
Named Executive Officers and Directors | ||||||
Harith Rajagopalan, M.D., Ph.D.(6) | 2,881,950 | 5.5% | ||||
Jay D. Caplan(7) | 1,001,546 | 2.0% | ||||
Lisa A. Davidson(8) | 629,839 | 1.2% | ||||
Kelly Barnes(9) | 100,368 | * | ||||
William W. Bradley(10) | 448,490 | * | ||||
Samuel Conaway(11) | 15,000 | * | ||||
Entities affiliated with Marc Elia(12) | 1,871,117 | 3.7% | ||||
Entities affiliated with Clive Meanwell, M.B., Ch.B., M.D.(13) | 292,890 | * | ||||
Ajay Royan(1)(14) | 6,445,102 | 12.8% | ||||
Amy W. Schulman(15) | 167,304 | * | ||||
All current executive officers and directors as a group (11 persons)(16) | 14,121,266 | 26.1% | ||||
* | Represents beneficial ownership of less than 1%. |
(1) | Based solely on a Schedule 13G filed on November 13, 2024. Consists of (a) 5,160,301 shares of common stock held by Mithril LP and (b) 1,251,900 shares of common stock held by Mithril II LP. Mithril GP LP is the general partner of Mithril LP and Mithril GP LP may be deemed to have shared voting, investment and dispositive power with respect to the securities held by Mithril LP. Mithril II UGP LLC is the general partner of Mithril II GP LP, which is the general partner of Mithril II LP and each of Mithril II UGP LLC and Mithril II GP LP may |
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(2) | Based on a Schedule 13G filed on February 14, 2024, and information known to the Company. Consists of (i) 4,673,870 shares of common stock for which CVF, LLC has shared voting power and shared dispositive power; (ii) 4,673,870 shares of common stock for which HCC Manager LLC has shared voting power and shared dispositive power; and (iii) 870,799 shares of common stock issuable upon exercise of the July 2023 Warrants at an assumed exercise price of $12.00. HCC Manager LLC, manager of CVF, LLC, exercises voting and investment power with respect to the shares held by CVF, LLC. The address of CVF, LLC is 222 N. LaSalle Street, Suite 2000, Chicago, IL 60601. |
(3) | Based on a Schedule 13G filed on November 14, 2024, and information known to the Company. Consists of (i) 4,248,492 shares of common stock for which Maverick Capital, Ltd. has shared voting power and shared dispositive power; (ii) 4,248,492 shares of common stock for which Maverick Capital Management, LLC has shared voting power and shared dispositive power; (iii) 4,248,492 shares of common stock for which Lee S. Ainslie III has shared voting power and shared dispositive power; (iv) 435,399 shares of common stock issuable to Maverick Designated Investments Fund, L.P. upon exercise of the July 2023 Warrants at an assumed exercise price of $12.00; and (v) 435,399 shares of common stock issuable to Maverick Growth Fund, L.P. upon exercise of the July 2023 Warrants at an assumed exercise price of $12.00. The address of each of these entities is c/o Maverick Capital, Ltd., 1900 N. Pearl Street, 20th Floor, Dallas, TX 75201. |
(4) | Based solely on a Schedule 13G filed on February 16, 2024. Consists of (i) 4,884,186 shares of common stock for which General Catalyst GP V, LLC (“GCGPV”) has shared voting power and shared dispositive power; (ii) 4,884,186 shares of common stock for which General Catalyst Partners V, L.P. (“GCGV GPLP”) has shared voting power and shared dispositive power; (iii) 4,884,186 for which General Catalyst Group V, L.P. (“GCGV”) has shared voting power and shared dispositive power; and (iv) 4,884,186 for which GC Entrepreneurs Fund V, L.P. (“GCEV” and, together with GCGPV, GCGV FPLP, and GCGV, the “Reporting Persons”) has shared voting power and shared dispositive power. General Catalyst Group Management Holdings GP, LLC (“GCGMH LLC”), is the general partner of General Catalyst Group Management Holdings, L.P. (“GCGMH”), which is the manager of General Catalyst Group Management, LLC (“GCGM”), which is the manager of GCGPV. GCGV GPLP is the sole general partner of GCGV and GCEV. GCGPV is the sole general partner of GCGV GPLP. GCGV is the record owner of 4,784,323 shares and GCEV is the record owner of 99,863 shares (collectively, the “Record Shares”). As the general partner of GCGMH, GCGMH LLC may be deemed to beneficially own the Record Shares. As the sole general partner of GC V and GCEV, GCGV GPLP may be deemed to beneficially own the Record Shares. As the sole general partner of GCGV GPLP, GCGPV may be deemed to beneficially own the Record Shares. By virtue of their relationship as affiliated entities who have overlapping general partners and managing directors, each Reporting Person may be deemed to share the power and direct the disposition and vote of the Record Shares. Both GCGMH LLC and GCGPV are controlled by a group of three or more individuals, or the Managing Directors, having shared voting and dispositive control over the shares held by GC V and GCEV. Under the so-called “rule of three,” because voting and dispositive decisions are made by a majority of both GCGMH LLC and GCGPV Managing Directors, no one of the Managing Directors is deemed to be a beneficial owner of the Issuer’s securities held by GCGV and GCEV. The principal business address of the foregoing entities and persons is 20 University Road, 4th Floor, Cambridge, MA 02138. |
(5) | Based solely on a Schedule 13G filed on February 14, 2025. Consists of (i) 2,576,288 shares of common stock held of record by BVP VII Special Opportunity Fund L.P. (“BVP SOF”) for which BVP SOF has sole voting and dispositive power; (ii) 1,526,689 shares of common stock held of record by Bessemer Venture Partners VII L.P. (“BVP VII”) for which BVP VII has sole voting and dispositive power; (iii) 667,924 shares of common stock held of record by Bessemer Venture Partners VII Institutional L.P. (“BVP VII Institutional”) for which BVP VII Institutional has sole voting and dispositive power; (iv) 4,770,901 shares of common stock for which Deer VII & Co. L.P. (“Deer VII L.P.”) has sole voting and dispositive power; and (v) 4,770,901 shares of common stock for which Deer VII & Co. Ltd. (“Deer VII Ltd.”) has sole voting and dispositive power. BVP SOF, BVP VII, and BVP VII Institutional, directly own shares of common stock. As the general partner of Deer VII LP, which in turn is the general partner of the funds, Deer VII Ltd may be deemed to beneficially own all of the shares of common stock held directly by the funds and have the power to direct the dividends from or the proceeds of the sale of such shares. The address of each of these entities is c/o Bessemer Venture Partners 1865 Palmer Avenue; Suite 104, Larchmont, NY 10583. |
(6) | Consists of (i) 491,329 shares of common stock held by Harith Rajagopalan; (ii) 602,980 shares of common stock held by various family trusts for which Dr. Rajagopalan serves as the investment advisor and, as a result, exercises voting and dispositive power with respect to such shares; and (iii) 1,787,641 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(7) | Consists of (i) 153,544 shares of common stock held by Jay D. Caplan; (ii) 477,616 shares of common stock held by various family trusts for which Mr. Caplan serves as the investment advisor and, as a result, exercises voting and dispositive power with respect to such shares; and (iii) 370,386 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(8) | Consists of (i) 7,525 shares of common stock; and (ii) 622,314 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(9) | Consists of (i) 31,000 shares of common stock; and (ii) 69,368 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(10) | Consists of (i) 16,129 shares of common stock; (ii) 186,393 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025 held of record by the Hillcrest Irrevocable Trust, of which Senator Bradley serves as sole trustee; and (iii) 245,968 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(11) | Consists of 15,000 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(12) | Consists of (i) 1,411,493 shares of common stock held by M28 Capital Master Fund LP (“M28 Capital”); (ii) 444,624 shares of common stock held by Sparviero LP; and (iii) 15,000 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. Marc Elia is a managing member of M28 Capital Fund GP LLC, the general partner of M28 Capital |
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(13) | Consists of (i) 277,890 shares of common stock held by Population Health Capital Partners II, L.P. (“PHPII”) and (ii) 15,000 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. Clive Meanwell, M.B., Ch.B., M.D., is the Founder of Population Health Partners GP, LLC, the general partner of PHPII, and, as a result, may be deemed to share voting and investment power with respect to the shares held by PHPII. Dr. Meanwell disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. The address of PHPII is 50 Mountaintop Road, Bernardsville, New Jersey 07924. |
(14) | Includes (i) 17,901 shares of common stock; and (ii) 15,000 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. See also footnote (1). |
(15) | Consists of (i) 8,550 shares of common stock; and (ii) 158,754 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
(16) | Consists of (i) 10,352,782 shares of common stock; and (ii) 3,768,484 shares of common stock underlying options currently exercisable or exercisable within 60 days of August 6, 2025. |
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• | by Internet: You can vote over the Internet at www.proxyvote.com by following the instructions on the proxy card; |
• | by Telephone: You can vote by telephone by calling 1-800-690-6903 and following the instructions on the proxy card; or |
• | by Mail: You can vote by mail by signing, dating and mailing the proxy card, which you may have received by mail. |
• | by submitting a duly executed proxy bearing a later date; |
• | by granting a subsequent proxy through the Internet or telephone; |
• | by giving written notice of revocation to our Corporate Secretary such that it is received prior to the Special Meeting; or |
• | by voting during the Special Meeting. |
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Proposal | Page Number | Voting Standard | Effect of Abstentions And Broker Non-Votes | ||||||||
Proposal No. 1: Approval of the issuance of shares of the Company’s common stock in accordance with Nasdaq Listing Rule 5635(d) and Nasdaq’s interpretations and guidance thereunder pursuant to the exercise of warrants sold in the Offering. | 3 | Affirmative vote of the holders of a majority in voting power of the votes cast on the matter | Abstentions and broker non-votes, if any, will have no effect. | ||||||||
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Proposal | Page Number | Voting Standard | Effect of Abstentions And Broker Non-Votes | ||||||||
Proposal No. 2: Approval of an adjournment of the Special Meeting, if necessary, to solicit additional proxies if there are not sufficient votes at the time of the Special Meeting to approve Proposal No. 1. | 5 | Affirmative vote of the holders of a majority in voting power of the votes cast on the matter | Abstentions and broker non-votes, if any, will have no effect. | ||||||||
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By Order of the Board of Directors, | |||
[ ] | |||
Sarah Toomey | |||
General Counsel and Corporate Secretary | |||
[ ], 2025 | |||
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