STOCK TITAN

Heartflow (NASDAQ: HTFL) grows 2025 revenue 40% but remains loss-making

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Heartflow, Inc. reported strong growth for the fourth quarter and full year 2025 while remaining unprofitable. Q4 revenue was $49.1 million, up 40% year-over-year, and full-year revenue reached $176.0 million, also up 40%, driven mainly by higher U.S. FFRCT volume.

Q4 gross margin improved to 79.5%, with full-year gross margin at 76.8%, reflecting AI-driven productivity gains. However, full-year operating expenses of $199.3 million (113% of revenue) led to a GAAP net loss of $116.8 million, or ($3.17) per share.

On a non-GAAP basis, full-year net loss narrowed to $59.9 million, and Adjusted EBITDA was ($44.7) million. Heartflow ended 2025 with $280.2 million in cash, cash equivalents and investments, providing a substantial liquidity cushion to support continued investment and growth initiatives.

Positive

  • None.

Negative

  • None.

Insights

Heartflow delivered 40% revenue growth with improving margins but continued sizable losses.

Heartflow generated Q4 2025 revenue of $49.1 million and full-year revenue of $176.0 million, both up 40% year-over-year, mainly from increased U.S. FFRCT volume. Gross margin expanded to 79.5% in Q4 and 76.8% for the year, helped by AI-driven productivity.

Operating expenses were high at $199.3 million for 2025, or 113% of revenue, reflecting expanded sales, technology and clinical investments. GAAP net loss was $116.8 million, while non-GAAP net loss improved to $59.9 million and Adjusted EBITDA to ($44.7) million, showing gradual operating leverage.

The balance sheet strengthened materially, with cash, cash equivalents and investments totaling $280.2 million as of December 31, 2025. This liquidity, combined with revenue growth and margin gains, provides capacity to sustain ongoing R&D, commercial expansion and clinical programs, though the path to profitability remains dependent on maintaining growth and cost discipline.

false000146452100014645212026-03-182026-03-18

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

______________________

FORM 8-K

______________________

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): March 18, 2026

______________________

Heartflow, Inc.

(Exact name of Registrant as Specified in Its Charter)

______________________

Delaware

001-42790

26-0506743

(State or Other Jurisdiction

of Incorporation)

(Commission File Number)

(IRS Employer

Identification No.)

331 E. Evelyn Avenue

Mountain View, California 94041

(Address of Principal Executive Offices) (Zip Code)

(650) 241-1221

(Registrant’s Telephone Number, Including Area Code)

N/A

(Former Name or Former Address, if Changed Since Last Report)

______________________

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, $0.001 par value per share

HTFL

The Nasdaq Stock Market LLC

(Nasdaq Global Select Market)

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company  x

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  ¨


Item 2.02 Results of Operations and Financial Condition.

On March 18, 2026, Heartflow, Inc. issued a press release regarding its financial results for the quarter and full year ended December 31, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Form 8-K and is incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

(d)Exhibits.

Exhibit No.

Description

99.1

Press Release of Heartflow, Inc. issued on March 18, 2026

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

The information contained in Items 2.02 and 9.01 to this Current Report on Form 8-K shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall such information be deemed to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.



SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

HEARTFLOW, INC.

Date: March 18, 2026

By:

/s/ Vikram Verghese

Vikram Verghese

Chief Financial Officer

 

 

Exhibit 99.1

Picture 1



Heartflow Reports Fourth Quarter and Full Year 2025 Financial Results

MOUNTAIN VIEW, Calif.March 18, 2026 – Heartflow, Inc. (Heartflow) (Nasdaq: HTFL), the leader in AI technology for coronary artery disease (CAD), today reported financial results for the fourth quarter and full year ended December 31, 2025.



Fourth Quarter 2025 Highlights

"

Total revenue of $49.1 million, a 40% increase year-over-year

"

Gross margin of 79.5%, non-GAAP gross margin of 79.9%

"

Net operating loss of $17.8 million, non-GAAP net operating loss of $12.5 million

"

U.S. installed base of 1,465 accounts as of December 31, 2025

"

U.S. Plaque installed base of 489 accounts as of December 31, 2025

"

Aetna began coverage of Heartflow Plaque Analysis, bringing total U.S. covered lives for Plaque to approximately 75%



2026 Annual Guidance

"

Total revenue of $218 million to $222 million (approximately 24% to 26% growth year-over-year)

"

Non-GAAP gross margin of 80% to 81%



“Our strong fourth quarter performance concluded a record year for Heartflow,” said John Farquhar, President and CEO of Heartflow. “The accelerating adoption of the Heartflow Platform, combined with our disciplined execution across commercial, innovation, and clinical initiatives, drove 40% fourth quarter and full year revenue growth and record gross margins. We also made significant strides in scaling account activations and driving early physician adoption of Heartflow Plaque Analysis. Our 2026 guidance reflects strong business fundamentals, a solid foundation for growth, and high confidence in consistent execution. With commercial, innovation and clinical catalysts on the horizon, our conviction in the business has never been higher.”



Fourth Quarter 2025 Financial Results

Total revenue was $49.1 million, a 40% increase year-over-year. U.S. revenue was $44.8 million, a 41% increase year-over-year. International and other revenue was $4.3 million, a 35% increase year-over-year. The year-over-year increase in total global revenue was primarily attributable to an increase in total U.S. FFRCT volume.



Gross profit was $39.1 million, compared to $26.3 million in the prior year period. Non-GAAP gross profit was $39.2 million, compared to $26.3 million in the prior year period.

Gross margin was 79.5%, compared to 75.0% in the prior year period. Non-GAAP gross margin was 79.9%, compared to 75.3% in the prior year period. The year-over-year gross margin expansion was primarily attributable to an increase in revenue case volume and improved production team productivity driven by AI efficiency initiatives, partially offset by the hiring and training of production team personnel.




 

Total operating expenses were $56.8 million, or 116% of total revenue, compared to $42.3 million, or 121% of total revenue, in the prior year period. Non-GAAP total operating expenses were $51.7 million, or 105% of total revenue, compared to $39.9 million, or 114% of total revenue, in the prior year period. The year-over-year operating expense increase was primarily attributable to increased investment in sales personnel and related expenses, as well as increased investments in technology and clinical research.

Net operating loss was $17.8 million, compared to $16.1 million in the prior year period. Non-GAAP net operating loss was $12.5 million, compared to $13.5 million in the prior year period.

Net loss was $24.4 million, or ($0.29) net loss per share, compared to $33.0 million, or ($5.59) net loss per share, in the prior year period. Net loss for the fourth quarters of 2025 and 2024 included a noncash charge of $9.3 million and $11.9 million, respectively, resulting from the remeasurement of the fair value of the Company’s common stock warrant liability. As of October 22, 2025, the warrant holder net exercised all warrants in full. Therefore, the fourth quarter of 2025 is the last quarter that movements in the Company’s stock price will trigger a warrant revaluation and result in a noncash charge to net loss.

Non-GAAP net loss was $9.8 million, or ($0.12) non-GAAP net loss per share, compared to $18.6 million, or ($3.15) non-GAAP net loss per share, in the prior year period.

Adjusted EBITDA was ($11.1) million, compared to ($12.0) million in the prior year period.

Full Year 2025 Financial Results

Total revenue was $176.0 million, a 40% increase year-over-year. U.S. revenue was $160.6 million, a 41% increase year-over-year. International and other revenue was $15.4 million, a 26% increase year-over-year. The year-over-year increase in total global revenue was primarily attributable to an increase in total U.S. FFRCT volume.

Gross profit was $135.2 million, compared to $94.4 million in the prior year period. Non-GAAP gross profit was $135.6 million, compared to $94.8 million in the prior year period.

Gross margin was 76.8%, compared to 75.1% in the prior year period. Non-GAAP gross margin was 77.0%, compared to 75.3% in the prior year period. The year-over-year gross margin expansion was primarily attributable to an increase in revenue case volume and improved production team productivity driven by AI efficiency initiatives, partially offset by the hiring and training of production team personnel.  



Total operating expenses were $199.3 million, or 113% of total revenue, compared to $155.7 million, or 124% of total revenue, in the prior year period. Non-GAAP total operating expenses were $185.7 million, or 105% of total revenue, compared to $145.8 million, or 116% of total revenue, in the prior year period. The year-over-year operating expense increase was primarily attributable to increased investment in personnel and related expenses, as well as increased investments in technology and clinical research.

Net operating loss was $64.1 million, compared to $61.2 million in the prior year period. Non-GAAP net operating loss was $50.1 million, compared to $51.0 million in the prior year period.

Net loss was $116.8 million, or ($3.17) net loss per share, compared to $96.4 million, or ($17.98) net loss per share, in the prior year period.

Non-GAAP net loss was $59.9 million, or ($1.62) non-GAAP net loss per share, compared to $69.6 million, or ($12.98) non-GAAP net loss per share, in the prior year period.


 

Adjusted EBITDA was ($44.7) million, compared to ($45.7) million in the prior year period.

Cash, cash equivalents and investments totaled $280.2 million as of December 31, 2025.

For additional information regarding non-GAAP financial measures, see “Use of Non-GAAP Measures,” “Heartflow GAAP to Non-GAAP Reconciliations” and “Reconciliation of GAAP Net Loss to Adjusted EBITDA” below.

Webcast and Conference Call Details

Heartflow will host a conference call today, March 18, 2026, at 1:30 p.m. PT / 4:30 p.m. ET to discuss its fourth quarter and full year 2025 financial results. Those interested in listening to the conference call should register online using this link. Once registered, participants will receive dial-in numbers and a unique pin to join the call. Participants are encouraged to register more than 15 minutes prior to the start of the call. A live and archived webcast of the event will also be available on the “Investor Relations” section of the Heartflow website at https://ir.heartflow.com/. The archived version will be available for 12 months following completion of the live call.

About Heartflow’s Technology and Research

Heartflow’s technology is redefining precision cardiovascular care through clinically-proven AI and the world’s largest coronary imaging dataset. Heartflow has been adopted by more than 1,800 institutions globally and continues to strengthen its commercial presence to make this cutting-edge solution more widely available to an increasingly diverse patient population. Backed by American College of Cardiology and American Heart Association (ACC/AHA) guidelines and supported by more than 600 peer-reviewed publications, Heartflow has redefined how clinicians manage care for nearly 600,000 patients worldwide1. Key benefits include:

Ï

Proprietary data pipeline: Built from more than 160 million annotated CTA images, Heartflow’s data foundation powers advanced AI models that deliver highly accurate, reproducible insights across diverse patient populations.

Ï

Extensive clinical and real-world validation: Heartflow’s AI-driven solutions have been validated through clinical evidence in over 200 studies assessing over 365,000 patients. Proven in real-world practice with reproducibility and accuracy, Heartflow’s coronary CTA image acceptance rates exceed 96%.

Ï

Seamless clinical integration via upgraded workflow: Heartflow delivers final quality-reviewed analyses instantly upon order, enabling clinicians to move from diagnosis to decision without delay.

Ï

Quality system, global security and patient-data integrity compliance: Heartflow meets or exceeds leading international standards, including HITRUST, SOC 2 Type 2, ISO 13485, and ISO 27001.



About Heartflow, Inc.

Heartflow is transforming coronary artery disease from the world’s leading cause of death into a condition that can be detected early, diagnosed accurately, and managed for life. The Heartflow One platform uses AI to turn coronary CTA images into personalized 3D models of the heart, providing clinically meaningful, actionable insights into plaque location, volume, and composition and its effect on blood flow — all without invasive procedures. Discover how we’re shaping the future of cardiovascular care at heartflow.com



Use of Non-GAAP Measures

To supplement its consolidated financial statements prepared in accordance with U.S. generally accepted accounting principles (GAAP), the Company discloses non-GAAP gross profit and non-GAAP gross margin, non-GAAP total operating expenses, non-GAAP research and development expense, non-GAAP selling, general and administrative expense, non-GAAP net operating loss, non-GAAP net loss, non-GAAP net loss per share, basic


 

and diluted, and Adjusted EBITDA (collectively, the “Non-GAAP Measures”) in this press release. As used by the Company, these measures are adjusted to exclude stock-based compensation expense from the comparable GAAP financial measure. Non-GAAP net loss and non-GAAP net loss per share, basic and diluted, are also adjusted for change in fair value of common stock warrant liability, change in fair value of derivative liability and loss on extinguishment of debt. In addition, Adjusted EBITDA is calculated by adding back to net loss or excluding, as appropriate, interest income and expense, provision for income taxes, and charges for depreciation and amortization and is further adjusted by adding back in or excluding, stock-based compensation and, as appropriate, other income and expense items that are not reflective of the Company’s underlying continuing operating performance. Reconciliations of the Non-GAAP Measures to their most directly comparable GAAP financial measures are provided in the financial statement tables included at the end of this press release, and investors are encouraged to review the reconciliations. The Company believes the presentation of the Non-GAAP Measures, when shown in conjunction with the corresponding GAAP measures, provides useful information to investors as it provides visibility to the Company’s underlying continuing operating performance from period to period by excluding the impact of stock-based compensation and certain other items that are not reflective of the Company’s ongoing operations. Because of the variety of equity awards used by companies, the varying methodologies for determining stock-based compensation expense, the subjective assumptions used in those determinations, and the volatility in valuations that can be driven by market conditions outside the Company’s control, we believe excluding stock-based compensation expense enhances the ability of management and investors to understand and assess the underlying performance of our business over time and compare it against our peers, a majority of whom also exclude stock-based compensation expense from their non-GAAP results. With respect to the presentation of Adjusted EBITDA, the Company believes it is a useful measure to evaluate the Company’s operating performance and it is used by the Company to evaluate ongoing operations and for planning and forecasting purposes. Adjusted EBITDA is also a measure frequently used by analysts, investors and other interested parties to evaluate companies in our same industry.



The Company’s definition of the Non-GAAP Measures may differ from similarly titled measures used by others. The Non-GAAP Measures should be considered only as a supplement to, and not as a substitute for, or superior to, their most directly comparable GAAP financial measures. Because the Non-GAAP Measures exclude the effect of items that increase or decrease the Company’s reported results of operations, management strongly encourages investors to review the reconciliations to the most comparable GAAP financial measures at the end of this press release and, when they become available, the Company’s consolidated financial statements and publicly filed Securities and Exchange Commission (“SEC”) reports in their entirety.



The Company is not able to provide a reconciliation without unreasonable efforts of its forward-looking guidance related to non-GAAP gross margin to the most directly comparable GAAP financial measure due to the unknown effect of stock-based compensation that is material to the comparable GAAP financial measure.



Forward-Looking Statements

This press release contains express or implied forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical facts contained in this press release, including statements regarding our strategy, expected market growth and financial guidance, are forward-looking statements. These forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements, including, but not limited to: we may not be able to achieve or sustain profitability; our dependence on the success of our one product, Heartflow FFRCT Analysis; healthcare providers may be unwilling to change their standard practice regarding the evaluation of coronary artery disease; adoption of the Heartflow Platform by healthcare providers may be negatively impacted if third-party payors, including government payors, do not cover or provide adequate reimbursement; the concentration of our customer base; the significant competition we face in an environment of rapid technological change; the commercialization of Heartflow Plaque Analysis is nascent; risks associated with our use and development of AI models; risks related to failing to properly manage our future growth; disruption by catastrophic events; risks associated with our


 

dependence on our information technology systems; security breaches that we cannot anticipate or successfully defend; extensive regulatory requirements we face to bring our products to market; and third parties could develop and commercial technology and products similar or identical to ours. For a more extensive description of these and other risks and uncertainties that could materially affect our results, you should read our filings with the SEC, including our Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as such filings may be amended, supplemented or superseded from time to time by other reports Heartflow files with the SEC. You should not place undue reliance on the forward-looking statements in this press release, which speak only as of the date hereof, and we undertake no obligation to update the forward-looking statements to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law.





Investor Contact

Nick Laudico

nlaudico@heartflow.com



Media Contact

Elliot Levy

elevy@heartflow.com








 



Heartflow, Inc.

Consolidated Statements of Operations

(unaudited, in thousands, except share and per share data)







 

 

 

 

 

 

 

 

 

 

 

 



 

Three Months Ended

 

Year Ended



 

December 31,

 

December 31,



 

 

2025

 

 

2024

 

 

2025

 

 

2024



 

 

 

 

 

 

 

 

 

 

 

 

Revenue

 

$

49,130 

 

$

34,977 

 

$

176,034 

 

$

125,808 

Cost of revenue

 

 

10,067 

 

 

8,727 

 

 

40,837 

 

 

31,359 

Gross profit

 

 

39,063 

 

 

26,250 

 

 

135,197 

 

 

94,449 

Operating Expenses:

 

 

 

 

 

 

 

 

 

 

 

 

Research and development

 

 

18,665 

 

 

12,279 

 

 

64,918 

 

 

43,517 

Selling, general and administrative

 

 

38,148 

 

 

30,029 

 

 

134,345 

 

 

112,154 

Total operating expenses

 

 

56,813 

 

 

42,308 

 

 

199,263 

 

 

155,671 

Loss from operations

 

 

(17,750)

 

 

(16,058)

 

 

(64,066)

 

 

(61,222)

Interest income

 

 

2,635 

 

 

592 

 

 

5,538 

 

 

4,066 

Interest expense

 

 

(8)

 

 

(5,152)

 

 

(15,173)

 

 

(22,768)

Change in fair value of common stock warrant liability

 

 

(9,308)

 

 

(11,905)

 

 

(43,894)

 

 

(16,395)

Change in fair value of derivative liability

 

 

-

 

 

-

 

 

7,311 

 

 

(222)

Loss on extinguishment of debt

 

 

-

 

 

-

 

 

(6,360)

 

 

-

Other income (expense), net

 

 

(129)

 

 

(447)

 

 

(223)

 

 

168 

Loss before provision for income taxes

 

 

(24,560)

 

 

(32,970)

 

 

(116,867)

 

 

(96,373)

(Provision for) benefit from income taxes

 

 

165 

 

 

(5)

 

 

76 

 

 

(53)

Net loss

 

$

(24,395)

 

$

(32,975)

 

$

(116,791)

 

$

(96,426)

Comprehensive loss:

 

 

 

 

 

 

 

 

 

 

 

 

Net loss

 

$

(24,395)

 

$

(32,975)

 

$

(116,791)

 

$

(96,426)

Other comprehensive income (loss):

 

 

 

 

 

 

 

 

 

 

 

 

Foreign currency translation gain (loss)

 

 

(69)

 

 

233 

 

 

191 

 

 

(271)

Unrealized gain on investments, net

 

 

156 

 

 

-

 

 

156 

 

 

-

Total other comprehensive income (loss)

 

 

87 

 

 

233 

 

 

347 

 

 

(271)

Total comprehensive loss

 

$

(24,308)

 

$

(32,742)

 

$

(116,444)

 

$

(96,697)



 

 

 

 

 

 

 

 

 

 

 

 

Net loss per share, basic and diluted

 

$

(0.29)

 

$

(5.59)

 

$

(3.17)

 

$

(17.98)

Weighted-average shares used to compute net loss per share, basic and diluted

 

 

84,828,694 

 

 

5,894,840 

 

 

36,853,867 

 

 

5,363,435 




 

Heartflow, Inc.

Consolidated Balance Sheets

(unaudited, in thousands)







 

 

 

 

 

 



 

December 31,



 

2025

 

2024

Assets

 

 

 

 

 

 

Current assets

 

 

 

 

 

 

Cash and cash equivalents

 

$

44,776 

 

$

51,367 

Short-term investments

 

 

132,010 

 

 

-

Accounts receivable, net

 

 

29,343 

 

 

24,639 

Restricted cash, current

 

 

-

 

 

150 

Prepaid expenses and other current assets

 

 

14,075 

 

 

6,132 

Total current assets

 

 

220,204 

 

 

82,288 

Long-term investments

 

 

103,365 

 

 

-

Property and equipment, net

 

 

8,587 

 

 

8,920 

Operating lease right-of-use assets

 

 

17,488 

 

 

18,805 

Restricted cash, non-current

 

 

4,709 

 

 

4,325 

Other non-current assets

 

 

5,099 

 

 

4,366 

Total assets

 

$

359,452 

 

$

118,704 



 

 

 

 

 

 

Liabilities, redeemable convertible preferred stock and stockholders’ equity (deficit)

 

 

 

 

 

 

Current liabilities

 

 

 

 

 

 

Accounts payable

 

$

3,169 

 

$

2,870 

Accrued expenses and other current liabilities

 

 

33,279 

 

 

25,319 

Operating lease liabilities, current portion

 

 

5,922 

 

 

5,416 

Total current liabilities

 

 

42,370 

 

 

33,605 

Term loan

 

 

-

 

 

136,431 

Common stock warrant liability

 

 

-

 

 

20,835 

Operating lease liabilities, non-current portion

 

 

16,132 

 

 

18,537 

Other non-current liabilities

 

 

303 

 

 

214 

Total liabilities

 

 

58,805 

 

 

209,622 

Redeemable convertible preferred stock issuable in series, $0.001 par value

 

 

-

 

 

768,566 

Stockholders’ equity (deficit)

 

 

 

 

 

 

Preferred stock, $0.001 par value

 

 

-

 

 

-

Common stock, $0.001 par value

 

 

85 

 

 

Additional paid-in capital

 

 

1,388,737 

 

 

112,241 

Accumulated other comprehensive income

 

 

(425)

 

 

(772)

Accumulated deficit

 

 

(1,087,750)

 

 

(970,959)

Total stockholders’ equity (deficit)

 

 

300,647 

 

 

(859,484)

Total liabilities, redeemable convertible preferred stock and stockholders’ equity (deficit)

 

$

359,452 

 

$

118,704 






 

Heartflow, Inc.

GAAP to Non-GAAP Reconciliations

(unaudited, in thousands except per share amounts and percentage data)







 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



 

 

Three Months Ended December 31, 2025

 

 

Three Months Ended December 31, 2024



 

 

GAAP

 

 

Adjustments

 

 

Non-GAAP

 

 

GAAP

 

 

Adjustments

 

 

Non-GAAP



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Gross profit

 

$

39,063 

 

$

184 

(a)

$

39,247 

 

$

26,250 

 

$

76 

(a)

$

26,326 

Gross margin

 

 

79.5% 

 

 

0.4% 

 

 

79.9% 

 

 

75.0% 

 

 

0.2% 

 

 

75.3% 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Operating Expenses:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research and development

 

$

18,665 

 

$

(1,547)

(a)

$

17,118 

 

$

12,279 

 

$

(585)

(a)

$

11,694 

Selling, general and administrative

 

$

38,148 

 

$

(3,529)

(a)

$

34,619 

 

$

30,029 

 

$

(1,853)

(a)

$

28,176 

Total operating expenses

 

$

56,813 

 

$

(5,076)

 

$

51,737 

 

$

42,308 

 

$

(2,438)

 

$

39,870 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Loss from operations

 

$

(17,750)

 

$

5,260 

 

$

(12,490)

 

$

(16,058)

 

$

2,514 

 

$

(13,544)



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net loss

 

$

(24,395)

 

$

14,568 

(b)

$

(9,827)

 

$

(32,975)

 

$

14,419 

(c)

$

(18,556)

Net loss per share, basic and diluted

 

$

(0.29)

 

$

0.17 

 

$

(0.12)

 

$

(5.59)

 

$

2.44 

 

$

(3.15)



(a)Represents adjustments related to stock-based compensation expense

(b)Represents adjustments for: (i) stock-based compensation expense of $5.3 million;  and (ii) change in fair value of common stock warrant liability of $9.3 million

(c)Represents adjustments for: (i) stock-based compensation expense of $2.5 million; and (ii) change in fair value of common stock warrant liability of $11.9 million









Heartflow, Inc.

GAAP to Non-GAAP Reconciliations

(unaudited, in thousands except per share amounts and percentage data)







 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



 

 

Year Ended December 31, 2025

 

 

Year Ended December 31, 2024



 

 

GAAP

 

 

Adjustments

 

 

Non-GAAP

 

 

GAAP

 

 

Adjustments

 

 

Non-GAAP



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Gross profit

 

$

135,197 

 

$

413 

(a)

$

135,610 

 

$

94,449 

 

$

307 

(a)

$

94,756 

Gross margin

 

 

76.8% 

 

 

0.2% 

 

 

77.0% 

 

 

75.1% 

 

 

0.2% 

 

 

75.3% 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Operating Expenses:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research and development

 

$

64,918 

 

$

(3,434)

(a)

$

61,484 

 

$

43,517 

 

$

(2,151)

(a)

$

41,366 

Selling, general and administrative

 

$

134,345 

 

$

(10,118)

(a)

$

124,227 

 

$

112,154 

 

$

(7,755)

(a)

$

104,399 

Total operating expenses

 

$

199,263 

 

$

(13,552)

 

$

185,711 

 

$

155,671 

 

$

(9,906)

 

$

145,765 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Loss from operations

 

$

(64,066)

 

$

13,965 

 

$

(50,101)

 

$

(61,222)

 

$

10,213 

 

$

(51,009)



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net loss

 

$

(116,791)

 

$

56,908 

(b)

$

(59,883)

 

$

(96,426)

 

$

26,830 

(c)

$

(69,596)

Net loss per share, basic and diluted

 

$

(3.17)

 

$

1.55 

 

$

(1.62)

 

$

(17.98)

 

$

5.00 

 

$

(12.98)



(a)Represents adjustments related to stock-based compensation expense

(b)Represents adjustments for: (i) stock-based compensation expense of $14.0 million; (ii) change in fair value of common stock warrant liability of $43.9 million; (iii) change in fair value of derivative liability of $7.3 million; and (iv) loss on extinguishment of debt of $6.4 million

(c)Represents adjustments for: (i) stock-based compensation expense of $10.2 million; (ii) change in fair value of common stock warrant liability of $16.4 million; and (iii) change in fair value of derivative liability of $0.2 million


 

Heartflow, Inc.

Reconciliation of GAAP Net Loss to Adjusted EBITDA

(unaudited, in thousands)





 

 

 

 

 

 

 

 

 

 

 

 



 

Three Months Ended

 

 

Year Ended



 

December 31,

 

 

December 31,



 

2025

 

2024

 

 

2025

 

 

2024



 

 

 

 

 

 

 

 

 

 

 

 

GAAP net loss

 

$

(24,395)

 

$

(32,975)

 

$

(116,791)

 

$

(96,426)

Non-GAAP adjustments:

 

 

 

 

 

 

 

 

 

 

 

 

Interest (income) expense, net

 

 

(2,627)

 

 

4,560 

 

 

9,635 

 

 

18,702 

Change in fair value of common stock warrant liability

 

 

9,308 

 

 

11,905 

 

 

43,894 

 

 

16,395 

Change in fair value of derivative liability

 

 

-

 

 

-

 

 

(7,311)

 

 

222 

Loss on extinguishment of debt

 

 

-

 

 

-

 

 

6,360 

 

 

-

Other (income) expense, net

 

 

129 

 

 

447 

 

 

223 

 

 

(168)

Provision for (benefit from) income taxes

 

 

(165)

 

 

 

 

(76)

 

 

53 

Depreciation and amortization

 

 

1,371 

 

 

1,591 

 

 

5,440 

 

 

5,358 

Stock-based compensation expense

 

 

5,260 

 

 

2,514 

 

 

13,965 

 

 

10,213 

Adjusted EBITDA

 

$

(11,119)

 

$

(11,953)

 

$

(44,661)

 

$

(45,651)




FAQ

How much revenue did Heartflow (HTFL) generate in Q4 2025?

Heartflow reported Q4 2025 revenue of $49.1 million, a 40% year-over-year increase. Growth was driven primarily by higher U.S. FFRCT volume, with U.S. revenue of $44.8 million and international and other revenue of $4.3 million in the quarter.

What were Heartflow’s full-year 2025 financial results?

For 2025, Heartflow generated $176.0 million in revenue, up 40% year-over-year. Gross profit was $135.2 million with a 76.8% gross margin. The company recorded a GAAP net loss of $116.8 million and a non-GAAP net loss of $59.9 million for the year.

How profitable is Heartflow (HTFL) on a GAAP and non-GAAP basis?

Heartflow remains unprofitable. In 2025 it posted a GAAP net loss of $116.8 million, or $3.17 per share. On a non-GAAP basis, excluding warrant, derivative and stock-based items, net loss improved to $59.9 million, or $1.62 per share, with Adjusted EBITDA at ($44.7) million.

How did Heartflow’s margins and operating expenses trend in 2025?

Heartflow’s 2025 gross margin improved to 76.8%, supported by higher case volumes and AI-driven productivity. Total operating expenses were $199.3 million, or 113% of revenue, reflecting increased spending on sales, technology and clinical research despite some operating leverage versus 2024.

What is Heartflow’s cash and investment position at year-end 2025?

As of December 31, 2025, Heartflow held $280.2 million in cash, cash equivalents and investments. This includes $44.8 million in cash and cash equivalents plus $235.4 million in short- and long-term investments, supporting ongoing growth and development activities.

How did non-cash warrant liability remeasurement affect Heartflow’s results?

Heartflow’s GAAP net loss includes non-cash charges from remeasuring its common stock warrant liability. In Q4 2025, this charge was $9.3 million; for the full year it was $43.9 million. These items are excluded from non-GAAP net loss and Adjusted EBITDA metrics.

Filing Exhibits & Attachments

4 documents
HEARTFLOW INC

NASDAQ:HTFL

View HTFL Stock Overview

HTFL Rankings

HTFL Latest News

HTFL Latest SEC Filings

HTFL Stock Data

2.30B
82.77M
Health Information Services
Surgical & Medical Instruments & Apparatus
Link
United States
MOUNTAIN VIEW