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Thyroid growth and tax gain drive Interpace Biosciences (IDXG) 2025 profit swing

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Interpace Biosciences reported Q4 2025 revenue of $9.2 million and full-year 2025 revenue of $38.7 million, both down versus 2024 but up versus thyroid-only pro forma comparisons. Income from continuing operations jumped to $22.8 million in Q4 and $25.0 million for the year, mainly from a one-time, non-cash tax-related accounting adjustment that released a deferred tax valuation allowance.

Thyroid testing remained the growth engine, with 2025 thyroid revenue up 21% and volume up 13% year-over-year. The company completed its shift to a thyroid-only diagnostics model, paid off its debt in Q4 2025, improved cash to $2.5 million, and moved stockholders’ equity from a deficit to a positive $22.4 million at year-end.

Positive

  • None.

Negative

  • None.

Insights

Results show strong thyroid growth, but profits rely on a one-time tax gain.

Interpace Biosciences grew its thyroid franchise, with 2025 thyroid revenue up 21% and test volume up 13% year-over-year. However, total 2025 revenue fell to $38.7 million from $46.9 million as the company exited PancraGEN and became a thyroid-only diagnostics business.

Income from continuing operations surged to $25.0 million, but this was largely driven by a one-time, non-cash tax-related accounting adjustment from releasing a deferred tax valuation allowance. Adjusted EBITDA declined to $5.4 million from $8.7 million, indicating underlying profitability is more modest than GAAP net income suggests.

Balance sheet quality improved: total liabilities fell to $11.5 million, stockholders’ equity turned positive at $22.4 million, and debt was fully repaid in Q4 2025. Future filings covering 2026 will clarify whether thyroid growth and operational efficiencies can offset the loss of PancraGEN revenue without one-time tax benefits.

Item 2.02 Results of Operations and Financial Condition Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Q4 2025 revenue $9.2 million Fourth quarter 2025 vs $12.4 million in Q4 2024
Full-year 2025 revenue $38.7 million Year ended December 31, 2025 vs $46.9 million in 2024
2025 income from continuing operations $25.0 million Benefiting from one-time, non-cash tax-related accounting adjustment
2025 thyroid revenue growth 21% year-over-year Thyroid revenue increase for full year 2025
2025 Adjusted EBITDA $5.4 million Year ended December 31, 2025 vs $8.7 million in 2024
Cash and cash equivalents $2.5 million As of December 31, 2025 vs $1.5 million a year earlier
Total stockholders’ equity $22.4 million As of December 31, 2025 vs $(2.2) million in 2024
2025 net cash from operating activities $5.8 million Net cash provided by operating activities for year ended 2025
Adjusted EBITDA financial
"Adjusted EBITDA was $5.4 million versus $8.7 million in the prior year"
Adjusted EBITDA is a way companies measure how much money they make from their core operations, like running a business, by removing certain costs or income that aren’t part of regular business activities. It helps investors see how well a company is doing without distractions from unusual expenses or gains, making it easier to compare companies or track performance over time.
Pro Forma financial
"and an increase of 17% from $33.2 million in the prior year Pro Forma."
Pro forma refers to financial information that is prepared based on estimates or adjustments to show what a company's results might look like under certain scenarios, such as new projects or acquisitions. It helps investors understand the potential impact of future events by providing a clear, hypothetical view of financial performance, much like a weather forecast shows possible future conditions.
deferred tax valuation allowance financial
"related to the release of a deferred tax valuation allowance."
A deferred tax valuation allowance is an accounting reserve companies set up when they doubt they will be able to use tax benefits recorded on their books, such as loss carryforwards or tax credits. Think of it as setting aside a coupon you’re not confident you’ll be able to redeem; if the allowance is increased, it reduces reported assets and can raise future tax expenses, signaling to investors concerns about the company’s ability to generate taxable profits.
PancraGEN financial
"excludes revenue and related costs from PancraGEN, which was discontinued in May 2025."
ThyGeNEXT® financial
"These results reflect the strength of our ThyGeNEXT® and ThyraMIR®v2 platform in the market"
ThyraMIR®v2 financial
"ThyraMIR®v2, used in combination with ThyGeNEXT®, for the diagnosis of thyroid cancer"
Q4 2025 revenue $9.2 million -26% vs reported Q4 2024; +20% vs Q4 2024 Pro Forma
Full-year 2025 revenue $38.7 million -18% vs reported 2024; +17% vs 2024 Pro Forma
Q4 2025 income from continuing operations $22.8 million vs $1.9 million in Q4 2024, boosted by tax adjustment
2025 income from continuing operations $25.0 million vs $6.9 million in 2024, driven by one-time tax benefit
2025 Adjusted EBITDA $5.4 million vs $8.7 million in 2024
Guidance

Company aims for approximately 16% year-over-year thyroid revenue growth under its thyroid-only operating model.

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934

 

Date of Report (Date of earliest event reported): March 30, 2026

 

INTERPACE BIOSCIENCES, INC.

(Exact name of registrant as specified in its charter)

 

Delaware   0-24249   22-2919486

(State or other jurisdiction

of incorporation)

 

(Commission

File Number)

 

(IRS Employer

Identification No.)

 

Waterview Plaza, Suite 310, 2001 Route 46

Parsippany, NJ 07054

(Address, including zip code, of principal executive offices)

 

(855) 776-6419

Registrant’s telephone number, including area code

 

Not Applicable

(Former name or former address, if changed since last report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
     
  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
     
  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
     
  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

Securities registered pursuant to Section 12(b) of the Act:

 

Title of each class   Trading Symbol(s)   Name of each exchange on which registered
None   N/A   N/A

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

 

Emerging growth company

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

 

 

 

 

 

 

Item 2.02 Results of Operations and Financial Condition.

 

On March 30, 2026, Interpace Biosciences, Inc. issued a press release announcing its results of operations and financial condition for the fourth quarter and fiscal year ended December 31, 2025. The full text of the press release is set forth as Exhibit 99.1 attached hereto and is incorporated herein by reference.

 

The information in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed to be incorporated by reference in any registration statement or other document filed under the Securities Act of 1933, as amended, or the Exchange Act, except as otherwise stated in such filing.

 

Item 9.01 Financial Statements and Exhibits.

 

(d) Exhibits.

 

Exhibit Number   Description
99.1   Press Release, dated March 30, 2026.
104   Cover Page Interactive Data File (embedded within the Inline XBRL document).

 

 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

INTERPACE BIOSCIENCES, INC.  
     
By: /s/ Thomas W. Burnell  
Name: Thomas W. Burnell  
Title: President and Chief Executive Officer  

 

Date: April 1, 2026

 

 

 

 

Exhibit 99.1

 

 

Interpace Biosciences Announces Fourth Quarter and Full Year 2025 Financial and Business Results

 

 

  Q4 and FY Revenue of $9.2 million and $38.7 million
  Q4 and FY Income from Continuing Operations of $22.8 million and $25.0 million (benefiting from a one-time, non-cash tax-related accounting adjustment)
  Q4 and FY Thyroid volume year-over-year increase of 11% and 13%
  Q4 and FY Thyroid revenue year-over-year increase of 14% and 21%

 

PARSIPPANY, NJ, March 30, 2026 (GLOBE NEWSWIRE) — Interpace Biosciences, Inc. (“Interpace” or the “Company”) (OTCQX: IDXG) today announced financial results for the fourth quarter and full year ended December 31, 2025 and provided a business and financial update.

 

Q4 and FY revenue were $9.2 million and $38.7 million, respectively. Q4 and FY income from continuing operations were $22.8 million and $25.0 million, respectively, benefiting from a one-time, non-cash tax-related accounting adjustment related to the release of a deferred tax valuation allowance. Q4 2025 thyroid revenue increased 14% year-over-year, and full year 2025 thyroid revenue increased 21% year-over-year.

 

“The Company delivered strong thyroid performance in the fourth quarter, capping a transformational year as we completed our transition to a thyroid-only diagnostics testing company,” said Chris McCarthy, Chief Financial Officer. “Thyroid revenue increased 14% year-over-year in Q4 2025 and 21% year-over-year for full year 2025, while thyroid test volume increased 11% and 13% year-over-year, respectively. Net income for the quarter and full year was driven in significant part by a one-time, non-cash accounting adjustment related to the release of a valuation allowance on deferred tax assets, which contributed meaningfully to income from continuing operations. These results reflect the strength of our ThyGeNEXT® and ThyraMIR®v2 platform in the market and our team’s execution on growth initiatives.”

 

McCarthy added, “Our strong financial position enabled continued investments in laboratory operational efficiency, leveraging AI and automation as part of our digital strategy. We further strengthened our balance sheet by fully paying off our debt in Q4 2025 and increased cash availability by $4.3 million year-over-year.”

 

“2025 marked a pivotal year for Interpace as we successfully navigated the PancraGEN discontinuation and emerged as a focused thyroid diagnostics company,” said Tom Burnell, President and CEO. “Our fourth quarter results demonstrate the resilience of our business model and the strength of our comprehensive thyroid testing platform. We believe our combination approach—ThyGeNEXT® for mutation detection and ThyraMIR®v2 for microRNA pathway insights—helps provide physicians the confidence and clarity they need to make informed patient-management decisions.”

 

Outlook

 

With a streamlined, thyroid-only operating model and strong commercial momentum, Interpace is positioned to accelerate execution in 2026. The Company remains focused on scaling thyroid test volume through deeper adoption within existing accounts and ongoing account growth, driving productivity gains through automation and operational discipline, and delivering on its previously provided guidance of approximately 16% year-over-year thyroid revenue growth.

 

Business Highlights

 

  Average thyroid revenue per test increased 5% year-over-year.
  Days sales outstanding (DSO) decreased 19% year-over-year.
  Turnaround time decreased 20% year-over-year.
  Average volume per account increased 6% year-over-year.
  Number of accounts increased 9% year-over-year.
  Percentage of new accounts converted to recurring accounts increased 10% year-over-year.

 

 

 

 

Fourth Quarter 2025 Financial Performance

 

For the Fourth Quarter of 2025 as Compared to the Fourth Quarter of 2024 and Pro Forma 2024 Results:

 

  Revenue was $9.2 million, a decrease of 26% from $12.4 million for the prior year quarter and an increase of 20% from $7.7 million for the prior year quarter Pro Forma.
  Gross Profit percentage was 66% compared to 64% for the prior year quarter and 57% for the prior year quarter Pro Forma.
  Operating income was $1.6 million versus operating income of $2.1 million in the prior year quarter and an operating loss of $4,000 in the prior year quarter Pro Forma.
  Income from continuing operations was $22.8 million (benefiting from a one-time, non-cash tax-related accounting adjustment) versus income from continuing operations of $1.9 million in the prior year quarter and a loss from continuing operations of $0.2 million in the prior year quarter Pro Forma.
  Adjusted EBITDA was $1.7 million versus $2.2 million in the prior year quarter and $0.2 million in the prior year quarter Pro Forma.
  Q4 2025 cash collections totaled $9.6 million compared to $11.2 million in the prior year quarter and $10.1 million in the prior year quarter Pro Forma.

 

Full Year 2025 Financial Performance

 

For the Year Ended 2025 as Compared to the Year Ended 2024 and Pro Forma 2024 Results:

 

  Revenue was $38.7 million, a decrease of 18% from $46.9 million in the prior year and an increase of 17% from $33.2 million in the prior year Pro Forma.
  Gross Profit percentage was 62% compared to 64% in the prior year and 59% in the prior year Pro Forma.
  Income from continuing operations was $25.0 million (benefiting from a one-time, non-cash tax-related accounting adjustment) versus income from continuing operations of $6.9 million in the prior year and $0.5 million in the prior year Pro Forma.
  Adjusted EBITDA was $5.4 million versus $8.7 million in the prior year and $2.3 million in the prior year Pro Forma.
  2025 cash collections totaled $41.7 million compared to $43.6 million in the prior year and $28.7 million in the prior year Pro Forma.

 

Management uses a non-GAAP Pro Forma income statement to help evaluate the results of our performance. The Pro Forma income statement for 2024 reflects the Company’s current business structure as a thyroid-only diagnostics testing company and excludes revenue and related costs from PancraGEN, which was discontinued in May 2025. These adjustments are presented for comparability purposes only and do not represent GAAP financial measures. Investors should review GAAP results alongside these pro forma figures for a complete understanding of performance. A reconciliation of GAAP and these pro forma figures is presented below.

 

About Interpace Biosciences

 

Interpace Biosciences is an emerging leader in enabling personalized medicine, offering specialized services along the therapeutic value chain from early diagnosis and prognostic planning to targeted therapeutic applications.

 

Clinical services, through Interpace Diagnostics, provide clinically useful molecular diagnostic tests and bioinformatics and pathology services for evaluating risk of cancer by leveraging the latest technology in personalized medicine for improved patient diagnosis and management. Interpace has two commercialized molecular tests: ThyGeNEXT® for the diagnosis of thyroid cancer from thyroid nodules utilizing a next-generation sequencing assay and ThyraMIR®v2, used in combination with ThyGeNEXT®, for the diagnosis of thyroid cancer utilizing a proprietary microRNA pairwise expression profiler along with algorithmic classification.

 

For more information, please visit Interpace Biosciences’ website at www.interpace.com.

 

 

 

 

Forward-Looking Statements

 

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995, relating to the Company’s future financial and operating performance. The Company has attempted to identify forward-looking statements by terminology including “believes,” “estimates,” “anticipates,” “expects,” “plans,” “projects,” “intends,” “potential,” “may,” “could,” “might,” “will,” “should,” “approximately” or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. These statements are based on current expectations, assumptions and uncertainties involving judgments about, among other things, future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond the Company’s control. These statements also involve known and unknown risks, uncertainties and other factors that may cause the Company’s actual results to be materially different from those expressed or implied by any forward-looking statements, including, but not limited to, the possibility that the Company’s estimates of future revenue, net income and adjusted EBITDA may prove to be materially inaccurate, the preliminary unaudited financial results being subject to audit review and adjustments, the Company’s prior history of operating losses, the Company’s ability to adequately finance its business, the Company’s dependence on sales and reimbursements from its clinical services, the Company’s ability to retain or secure reimbursement including its reliance on third parties to process and transmit claims to payers and the adverse impact of any delay, data loss, or other disruption in processing or transmitting such claims, and the Company’s revenue recognition being based in part on estimates for future collections which estimates may prove to be incorrect.

 

Additionally, all forward-looking statements are subject to the “Risk Factors” detailed from time to time in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2025, Current Reports on Form 8-K and Quarterly Reports on Form 10-Q filed with the Securities and Exchange Commission. Because of these and other risks, uncertainties and assumptions, undue reliance should not be placed on these forward-looking statements. In addition, these statements speak only as of the date of this press release and, except as may be required by law, the Company undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

 

Contacts

 

Investor Relations

Interpace Biosciences, Inc.

(855)-776-6419

Info@Interpace.com

 

 

 

 

INTERPACE BIOSCIENCES, INC.

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(in thousands, except per share data)

 

   Three Months Ended   Years Ended 
   December 31,   December 31, 
   2025   2024   2025   2024 
   (unaudited)         
Revenue, net  $9,224   $12,411   $38,728   $46,926 
Cost of revenue   3,180    4,504    14,598    17,001 
Gross Profit   6,044    7,907    24,130    29,925 
                     
Sales and marketing   2,114    3,084    9,924    11,655 
Research and development   142    194    642    676 
General and administrative   2,211    2,567    9,480    9,486 
Total operating expenses   4,467    5,845    20,046    21,817 
                     
Operating income   1,577    2,062    4,084    8,108 
Interest accretion expense   -    -    -    (34)
Note payable interest expense   (12)   (110)   (168)   (625)
Other expense, net   (30)   (95)   (142)   (499)
Income from continuing operations before tax   1,535    1,857    3,774    6,950 
(Benefit) provision for income taxes   (21,217)   (8)   (21,210)   4 
Income from continuing operations   22,752    1,865    24,984    6,946 
                     
(Loss) income from discontinued operations, net of tax   (95)   16    (409)   (244)
                     
Net income   22,657    1,881    24,575    6,702 
                     
Less adjustment for preferred stock deemed dividend   -    (464)   -    (464)
                     
Net income attributable to common stockholders  $22,657   $1,417   $24,575   $6,238 
                     
Basic income (loss) per share of common stock:                    
From continuing operations  $5.14   $0.32   $5.65   $1.48 
From discontinued operations   (0.02)   0.00    (0.09)   (0.06)
Net income (loss) per basic share of common stock  $5.12   $0.32   $5.55   $1.42 
                     
Diluted income (loss) per share of common stock:                    
From continuing operations  $0.82   $0.05   $0.90   $0.41 
From discontinued operations   (0.00)   0.00    (0.01)   (0.02)
Net income (loss) per diluted share of common stock  $0.82   $0.05   $0.89   $0.40 
                     
Weighted average number of common shares and common share equivalents outstanding:                    
Basic   4,429    4,406    4,424    4,387 
Diluted   27,705    26,132    27,695    15,734 

 

 

 

 

Selected Balance Sheet Data

($ in thousands)

 

   December 31,   December 31, 
   2025   2024 
         
Cash and cash equivalents  $2,505   $1,461 
           
Total current assets   9,900    11,773 
Total current liabilities   5,103    10,615 
           
Total assets   33,838    14,792 
Total liabilities   11,475    17,009 
Total stockholders’ equity (deficit)   22,363    (2,217)

 

 

 

 

Selected Cash Flow Data

($ in thousands)

 

   For the Years Ended 
   December 31, 
   2025   2024 
         
Net income  $24,575   $6,702 
           
Net cash provided by operating activities  $5,831   $4,646 
Net cash used in investing activities   (356)   (876)
Net cash used in financing activities   (4,431)   (5,807)
Change in cash and cash equivalents   1,044    (2,037)
Cash and cash equivalents – beginning   1,461    3,498 
Cash and cash equivalents – ending  $2,505   $1,461 

 

 

 

 

Reconciliation of Pro Forma (Unaudited)

(in thousands, except per share data)

 

   Three Months Ended December 31, 2024 
       PancraGEN     
   As Reported   Direct Costs*   Pro Forma 
             
Revenue, net  $12,411   $4,715   $7,696 
Cost of revenue   4,504    1,212    3,292 
Gross Profit   7,907    3,503    4,404 
                
Sales and marketing   3,084    1,233    1,851 
Research and development   194    78    116 
General and administrative   2,567    126    2,441 
Total operating expenses   5,845    1,437    4,408 
                
Operating income   2,062    2,066    (4)
                
Note payable interest   (110)   -    (110)
Other expense, net   (95)   -    (95)
Income from continuing operations before  tax   1,857    2,066    (209)
Benefit for income taxes   (8)   -    (8)
Income from continuing operations   1,865    2,066    (201)
                
Income from discontinued operations, net of tax   16    -    16 
                
Net income   1,881    2,066    (185)
                
Less adjustment for preferred stock deemed dividend   (464)   -    (464)
                
Net income (loss) attributable to common stockholders  $1,417   $2,066   $(649)
                
Basic income (loss) per share of common stock:               
From continuing operations  $0.32   $0.47   $(0.15)
From discontinued operations   0.00    -    0.00 
Net income (loss) per basic share of common stock  $0.32   $0.47   $(0.15)
                
Diluted income (loss) per share of common stock:               
From continuing operations  $0.05   $0.08   $(0.03)
From discontinued operations   0.00    -    0.00 
Net income (loss) per diluted share of common stock  $0.05   $0.08   $(0.02)
                
Weighted average number of common shares and common share equivalents outstanding:               
Basic   4,406    4,406    4,406 
Diluted   26,132    26,132    26,132 

 

 

 

 

   Year Ended December 31, 2024 
       PancraGEN     
   As Reported   Direct Costs*   Pro Forma 
             
Revenue, net  $46,926   $13,725   $33,201 
Cost of revenue   17,001    3,470    13,531 
Gross Profit   29,925    10,255    19,670 
                
Sales and marketing   11,655    3,266    8,389 
Research and development   676    203    473 
General and administrative   9,486    347    9,139 
Total operating expenses   21,817    3,816    18,001 
                
Operating income   8,108    6,439    1,669 
                
Interest accretion expense   (34)   -    (34)
Note payable interest   (625)   -    (625)
Other expense, net   (499)   -    (499)
Income from continuing operations before  tax   6,950    6,439    511 
Provision for income taxes   4    -    4 
Income from continuing operations   6,946    6,439    507 
                
Loss from discontinued operations, net of tax   (244)   -    (244)
                
Net income   6,702    6,439    263 
                
Less adjustment for preferred stock deemed dividend   (464)   -    (464)
                
Net income (loss) attributable to common stockholders  $6,238   $6,439   $(201)
                
Basic income (loss) per share of common stock:               
From continuing operations  $1.48   $1.47   $0.01 
From discontinued operations   (0.06)   -    (0.06)
Net income (loss) per basic share of common stock  $1.42   $1.47   $(0.05)
                
Diluted income (loss) per share of common stock:               
From continuing operations  $0.41   $0.41   $0.00 
From discontinued operations   (0.02)   -    (0.02)
Net income (loss) per diluted share of common stock  $0.40   $0.41   $(0.01)
                

Weighted average number of common shares and

common share equivalents outstanding:

               
Basic   4,387    4,387    4,387 
Diluted   15,734    15,734    15,734 

 

* PancraGEN Direct Costs represent only direct costs associated with the operations of PancraGEN testing, with no allocations or estimates of corporate, shared, or overhead expenses included.

 

 

 

 

Reconciliation of Adjusted EBITDA (Unaudited)

($ in thousands)

 

   Three Months Ended   Years Ended 
   December 31,   December 31, 
   2025   2024   2025   2024 
Income from continuing operations (GAAP Basis)  $22,752   $1,865   $24,984   $6,946 
Depreciation and amortization   118    95    425    300 
Stock-based compensation   4    72    35    291 
Severance & related expense   -    -    692    - 
Asset impairment - lab supplies   -    -    198    - 
Tax (benefit) expense   (21,217)   (8)   (21,210)   4 
Interest accretion expense   -    -    -    34 
Financing interest and related costs   12    110    168    625 
Interest income   7    (8)   32    (48)
Change in fair value of note payable   23    103    110    547 
Adjusted EBITDA  $1,699   $2,229   $5,434   $8,699 

 

Non-GAAP Financial Measures

 

In addition to the United States generally accepted accounting principles, or GAAP, results provided throughout this document, we have provided certain non-GAAP financial measures to help evaluate the results of our performance. We believe that these non-GAAP financial measures, when presented in conjunction with comparable GAAP financial measures, are useful to both management and investors in analyzing our ongoing business and operating performance. We believe that providing the non-GAAP information to investors, in addition to the GAAP presentation, allows investors to view our financial results in the way that management views financial results.

 

In this document, we discuss Adjusted EBITDA, a non-GAAP financial measure. Adjusted EBITDA is a metric used by management to measure cash flow of the ongoing business. Adjusted EBITDA is defined as income or loss from continuing operations, plus depreciation and amortization, non-cash stock-based compensation, severance expense, interest and taxes, and other non-cash expenses including change in fair values of notes payable. The table above includes a reconciliation of this non-GAAP financial measure to the most directly comparable GAAP financial measure.

 

 

 

 

FAQ

How did Interpace Biosciences (IDXG) perform financially in Q4 2025?

Interpace Biosciences reported Q4 2025 revenue of $9.2 million, down from $12.4 million a year earlier but up from pro forma thyroid-only revenue. Income from continuing operations rose sharply to $22.8 million, primarily due to a one-time, non-cash tax-related accounting adjustment.

What were Interpace Biosciences’ (IDXG) full-year 2025 results?

For 2025, Interpace Biosciences generated revenue of $38.7 million, compared with $46.9 million in 2024 and $33.2 million on a thyroid-only pro forma basis. Income from continuing operations increased to $25.0 million, largely driven by a non-cash tax valuation allowance release.

How is Interpace Biosciences’ (IDXG) thyroid business performing?

Interpace’s thyroid segment delivered strong growth in 2025, with thyroid revenue up 21% year-over-year and thyroid test volume up 13%. Average thyroid revenue per test rose 5%, and the number of accounts grew 9%, reflecting deeper adoption of the ThyGeNEXT® and ThyraMIR®v2 testing platform.

What changed in Interpace Biosciences’ (IDXG) business model in 2025?

In 2025, Interpace discontinued its PancraGEN testing in May and completed its transition to a thyroid-only diagnostics business. Management provides pro forma 2024 figures excluding PancraGEN to help investors compare results and highlight growth from its core thyroid testing franchise.

How did Interpace Biosciences’ (IDXG) profitability and Adjusted EBITDA trend?

GAAP income from continuing operations rose to $24.98 million in 2025 from $6.95 million in 2024, mainly due to a tax-related adjustment. However, Adjusted EBITDA declined to $5.43 million from $8.70 million, reflecting lower revenue after discontinuing PancraGEN and normal operating performance.

What is Interpace Biosciences’ (IDXG) balance sheet position at December 31, 2025?

At December 31, 2025, Interpace held $2.5 million in cash and cash equivalents, with total assets of $33.8 million and total liabilities of $11.5 million. Stockholders’ equity improved significantly to a positive $22.4 million, compared with a deficit of $2.2 million a year earlier.

What 2026 outlook did Interpace Biosciences (IDXG) provide for thyroid revenue?

Interpace stated it aims to deliver approximately 16% year-over-year thyroid revenue growth in 2026. The company plans to scale test volume through deeper adoption in existing accounts, new account growth, and continued automation and operational efficiency in its thyroid-only diagnostics operations.

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