Filed by InMed Pharmaceuticals
Inc.
pursuant to Rule 425 under
the Securities Act of 1933
and deemed filed pursuant
to Rule 14a-12
under the Securities Exchange
Act of 1934
Subject Company: InMed
Pharmaceuticals Inc.
Commission File No.: 333-297234
Date: July 20, 2026
This filing relates to the proposed transaction
pursuant to the terms of that certain Agreement and Plan of Merger and Reorganization dated as of May 19, 2026 (as may be amended
from time to time, the “Merger Agreement”), by and among InMed Pharmaceuticals Inc., a company incorporated under the
laws of the Province of British Columbia (“InMed”), Indigo Merger Sub Corp., a Delaware corporation and a wholly owned
subsidiary of InMed (the “First Merger Sub”), Indigo Merger Sub II, LLC, a Delaware limited liability company and a
wholly owned subsidiary of InMed (the “Second Merger Sub” and, together with First Merger Sub, the “Merger
Subs”), and Mentari Therapeutics, Inc., a Delaware corporation (“Mentari”), pursuant to which, among other
matters and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, (i) the First Merger Sub will merge
with and into Mentari, with Mentari surviving the merger as a wholly owned subsidiary of InMed (the “First Merger”),
and (ii) immediately following the First Merger and as part of the same overall transaction as the First Merger, Mentari will merge with
and into the Second Merger Sub, with the Second Merger Sub surviving such merger (the “Second Merger” and, together
with the First Merger, the “Merger”).
On July 20,
2026, Mentari published the following communication:
|
Mentari Therapeutics Appoints
Industry Veteran Greg Divis as
Chief Executive Officer |
 |
Former Avadel CEO brings a proven track record
of strategic leadership, M&A expertise, and commercial success to lead Mentari as it advances potentially best-in-class therapies
for the prevention of migraine
Mentari is on-track for regulatory filings to support the advancement
of MT-001, an anti-PACAP antibody, in MY 2026 and MT-002, an anti-PACAP and anti-CGRP bispecific antibody, in Q1 2027
WALTHAM, Mass., July 20, 2026 /PRNewswire/ -- Mentari Therapeutics,
Inc., a privately held biotechnology company developing therapies for the prevention of migraine, today announced the appointment of Greg
Divis as Chief Executive Officer and member of the Board of Directors, effective July 20, 2026.
“Greg brings proven experience to Mentari during its foundational
period of growth. He is the ideal choice to lead as we rapidly advance MT-001 and MT-002 through clinical development and position Mentari
as a leader in migraine prevention,” said Julianne Bruno, Chair of the Board of Directors at Mentari Therapeutics and Growth Partner
at Fairmount. “His experience successfully commercializing Lumryz® and delivering on the acquisition by Alkermes
demonstrates his ability to build shareholder value while also delivering meaningful therapies for patients.”
“Mentari’s approach to migraine prevention, initially targeting
the complementary and validated PACAP and CGRP pathways, represents an opportunity to deliver enhanced migraine relief for patients who
continue to suffer with the current standard of care,” said Divis. “With MT-002 also designed for convenient subcutaneous
delivery, Mentari is well-positioned to lead the next wave of migraine treatment. I am excited about Mentari’s entire pipeline,
which offers a clear path to value creation, as well as versatility through its novel targets and potential to build next-generation combination
therapies that may deliver migraine freedom to more patients. I am honored to join this talented team.”
Divis joins Mentari after serving as the CEO of Avadel Pharmaceuticals,
where he led the company through the successful development, FDA approval, and commercial launch of Lumryz® (sodium oxybate), a treatment
for narcolepsy. Under his tenure, Divis transformed Avadel from a development-stage company into a fully integrated commercial organization,
ultimately overseeing Avadel’s sale to Alkermes in a transaction valued at up to $2.4 billion. With over 30 years of industry experience,
he previously served as an Operating Partner for Linden Capital Partners, President & CEO at Lumara Health, President of Ther-Rx Corporation,
and Vice President at Sanofi-Aventis (now Sanofi) and Schering-Plough (now Merck & Co.).
About Mentari Therapeutics
Mentari Therapeutics is a biotechnology
company developing therapies for the prevention of migraine to deliver freedom from this debilitating and undertreated neurological condition
that affects more than 1 billion people globally. Mentari’s lead programs target PACAP, a newly validated target that is mechanistically
independent from CGRP, one of the first migraine targets to yield clinical and commercial success. Mentari’s pipeline includes
MT-001, an anti-PACAP monoclonal antibody designed for convenient subcutaneous dosing, and MT-002, an anti-PACAP and anti-CGRP bispecific
antibody designed to inhibit these complementary pathways with potential to deliver superior outcomes for people with incomplete response
to CGRP-targeted therapies. The company’s programs were discovered by Paragon Therapeutics. Mentari is based in Waltham, MA. For
more information, visit mentaritx.com.
Forward-Looking Statements
This communication contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933,
as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended, including, without
limitation, statements regarding the proposed merger of InMed Pharmaceuticals Inc. (“InMed”) and Mentari Therapeutics, Inc.
(“Mentari”); the expected timing, completion and anticipated benefits of the merger; the anticipated timing of regulatory
filings for, and the development, potential benefits and therapeutic potential of, MT-001 and MT-002; and the strategy, plans, objectives
and leadership of Mentari and the combined company. Words such as “anticipate,” “believe,” “expect,”
“intend,” “plan,” “potential,” “will” and similar expressions identify forward-looking
statements. These statements are based on current expectations and are subject to risks and uncertainties that could cause actual results
to differ materially, including, among others: the risk that the merger may not be completed on the anticipated timeline or at all; the
failure to obtain the required InMed shareholder and Mentari stockholder approvals or to satisfy other closing conditions, including effectiveness
of the registration statement on Form S-4; the risk that any concurrent financing is not completed on the expected terms or at all; risks
relating to the redomestication, reverse stock split and Nasdaq continued-listing requirements; risks inherent in preclinical and clinical
development, the regulatory review and approval process and commercialization of product candidates; and the other risks described in
InMed’s filings with the U.S. Securities and Exchange Commission (the “SEC”) and applicable Canadian securities regulators,
including the Form S-4 and the proxy statement/prospectus and management information circular relating to the merger. Because forward-looking
statements are inherently subject to risks and uncertainties, you should not rely on them as predictions of future events. Except as required
by law, neither InMed nor Mentari undertakes any obligation to update any forward-looking statement.
No Offer or Solicitation
This communication is for informational purposes only and does not constitute an offer to sell, or the solicitation of an offer to
buy, any securities, or the solicitation of any vote or approval, nor shall there be any sale of securities in any jurisdiction in which
such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction.
Without limiting the foregoing, this communication does not constitute an offer to sell, or the solicitation of an offer to buy, any securities
in connection with any private placement or other financing by Mentari or InMed. Any such securities have not been and will not be registered
under the Securities Act or any state securities laws and may not be offered or sold in the United States absent registration or an applicable
exemption from registration. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section
10 of the Securities Act or an applicable exemption therefrom.
Important Additional Information About the Merger and Where to Find
It
In connection with the proposed merger, InMed has filed with the SEC a registration statement on Form S-4 that includes a preliminary
proxy statement/prospectus of InMed and a management information circular and will file other relevant documents with the SEC and applicable
Canadian securities regulators. The Form S-4 has not yet become effective. After the Form S-4 is declared effective, InMed will mail a
definitive proxy statement/prospectus and management information circular to its shareholders and to Mentari’s stockholders. INVESTORS
AND SECURITYHOLDERS OF INMED AND MENTARI ARE URGED TO READ THE FORM S-4, THE PROXY STATEMENT/PROSPECTUS AND MANAGEMENT INFORMATION CIRCULAR
(INCLUDING ALL AMENDMENTS AND SUPPLEMENTS) AND ALL OTHER RELEVANT DOCUMENTS FILED OR TO BE FILED WITH THE SEC AND CANADIAN SECURITIES
REGULATORS, CAREFULLY AND IN THEIR ENTIRETY WHEN THEY BECOME AVAILABLE, BECAUSE THEY CONTAIN OR WILL CONTAIN IMPORTANT INFORMATION ABOUT
INMED, MENTARI, THE MERGER AND RELATED MATTERS. Investors and securityholders may obtain free copies of these documents (when available)
through the SEC’s website at www.sec.gov, on SEDAR+ at www.sedarplus.ca, or from InMed at inmedpharma.com/investors.
Participants in the Solicitation
InMed, Mentari and their
respective directors and executive officers may be deemed to be participants in the solicitation of proxies from InMed’s
shareholders and Mentari’s stockholders in connection with the proposed merger. Information regarding InMed’s directors
and executive officers and a description of their direct and indirect interests, by security holdings or otherwise, is set forth in
InMed’s most recent annual report [on Form 10-K / Form 40-F, as applicable] and its other filings with the SEC and on SEDAR+.
Additional information regarding the participants and their interests is or will be contained in the proxy statement/prospectus and
management information circular and other relevant materials filed or to be filed with the SEC and Canadian securities regulators.
These documents may be obtained free of charge as described above.
Media Contact:
Lia Dangelico
Deerfield Group
lia.dangelico@deerfieldgroup.com
Forward-Looking Statements
This communication contains “forward-looking
statements” within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”),
and Section 21E of the Securities Exchange Act of 1934, as amended, including, without limitation, statements regarding the proposed merger
of InMed and Mentari; the expected timing, completion and anticipated benefits of the merger; the anticipated timing of regulatory filings
for, and the development, potential benefits and therapeutic potential of, MT-001 and MT-002; and the strategy, plans, objectives and
leadership of Mentari and the combined company. Words such as “anticipate,” “believe,” “expect,” “intend,”
“plan,” “potential,” “will” and similar expressions identify forward-looking statements. These statements
are based on current expectations and are subject to risks and uncertainties that could cause actual results to differ materially, including,
among others: the risk that the merger may not be completed on the anticipated timeline or at all; the failure to obtain the required
InMed shareholder and Mentari stockholder approvals or to satisfy other closing conditions, including effectiveness of the registration
statement on Form S-4; the risk that any concurrent financing is not completed on the expected terms or at all; risks relating to the
redomestication, reverse stock split and Nasdaq continued-listing requirements; risks inherent in preclinical and clinical development,
the regulatory review and approval process and commercialization of product candidates; and the other risks described in InMed’s filings
with the U.S. Securities and Exchange Commission (the “SEC”) and applicable Canadian securities regulators, including
the Form S-4 and the proxy statement/prospectus and management information circular relating to the merger. Because forward-looking statements
are inherently subject to risks and uncertainties, you should not rely on them as predictions of future events. Except as required by
law, neither InMed nor Mentari undertakes any obligation to update any forward-looking statement.
No Offer or Solicitation
This communication is not intended to and
does not constitute (i) a solicitation of a proxy, consent or approval with respect to any securities or in respect of the proposed
transaction or (ii) an offer to sell or the solicitation of an offer to subscribe for or buy or an invitation to purchase or subscribe
for any securities pursuant to the proposed transaction or otherwise, nor shall there be any sale, issuance or transfer of securities
in any jurisdiction in contravention of applicable law. No offer of securities shall be made except by means of a prospectus meeting the
requirements of the Securities Act or an exemption therefrom. Subject to certain exceptions to be approved by the relevant regulators
or certain facts to be ascertained, the public offer will not be made directly or indirectly, in or into any jurisdiction where to do
so would constitute a violation of the laws of such jurisdiction, or by use of the mails or by any means or instrumentality (including
without limitation, facsimile transmission, telephone and the internet) of interstate or foreign commerce, or any facility of a national
securities exchange, of any such jurisdiction.
NEITHER THE SEC NOR ANY STATE SECURITIES COMMISSION
HAS APPROVED OR DISAPPROVED OF THE SECURITIES OR DETERMINED IF THIS COMMUNICATION IS TRUTHFUL OR COMPLETE.
Important Additional Information About
the Proposed Transaction
In connection
with the proposed merger, InMed has filed with the SEC a registration statement on Form S-4 that includes a preliminary proxy statement/prospectus
of InMed and a management information circular and will file other relevant documents with the SEC and applicable Canadian securities
regulators. The Form S-4 has not yet become effective. After the Form S-4 is declared effective, InMed will mail a definitive proxy statement/prospectus
and management information circular to its shareholders and to Mentari’s stockholders. INVESTORS AND SECURITYHOLDERS OF INMED AND MENTARI
ARE URGED TO READ THE FORM S-4, THE PROXY STATEMENT/PROSPECTUS AND MANAGEMENT INFORMATION CIRCULAR (INCLUDING ALL AMENDMENTS AND SUPPLEMENTS)
AND ALL OTHER RELEVANT DOCUMENTS FILED OR TO BE FILED WITH THE SEC AND CANADIAN SECURITIES REGULATORS, CAREFULLY AND IN THEIR ENTIRETY
WHEN THEY BECOME AVAILABLE, BECAUSE THEY CONTAIN OR WILL CONTAIN IMPORTANT INFORMATION ABOUT INMED, MENTARI, THE MERGER AND RELATED MATTERS.
Investors and securityholders may obtain free copies of these documents (when available) through the SEC’s website at www.sec.gov,
on SEDAR+ at www.sedarplus.ca, or from InMed at inmedpharma.com/investors.
Participants in the Solicitation
InMed, Mentari and their respective directors
and executive officers may be deemed to be participants in the solicitation of proxies from InMed’s shareholders and Mentari’s stockholders
in connection with the proposed merger. Information regarding InMed’s directors and executive officers and a description of their direct
and indirect interests, by security holdings or otherwise, is set forth in InMed’s most recent annual report on Form 10-K and its other
filings with the SEC and on SEDAR+. Additional information regarding the participants and their interests is or will be contained in the
proxy statement/prospectus and management information circular and other relevant materials filed or to be filed with the SEC and Canadian
securities regulators. These documents may be obtained free of charge as described above.