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Ionis Pharmaceuticals SEC Filings

IONS NASDAQ

Welcome to our dedicated page for Ionis Pharmaceuticals SEC filings (Ticker: IONS), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Ionis Pharmaceuticals’ 10-K doesn’t just list numbers; it weaves together antisense pipeline updates, milestone revenues from Biogen and AstraZeneca, and detailed R&D spend that often tops hundreds of millions. Parsing how each clinical program moves from discovery to Phase 3—and how those decisions flow through revenue recognition rules—can be overwhelming.

Stock Titan’s AI lifts that burden. Our platform delivers Ionis Pharmaceuticals SEC filings explained simply, turning the dense language of a 300-page annual report into plain-English takeaways. Get real-time alerts whenever an Ionis Pharmaceuticals 8-K material events explained filing hits EDGAR, see Ionis Pharmaceuticals insider trading Form 4 transactions the moment executives trade shares, and drill into each Ionis Pharmaceuticals quarterly earnings report 10-Q filing with side-by-side historical comparisons. Need to monitor Ionis Pharmaceuticals executive stock transactions Form 4? Our AI tags every purchase, sale or option exercise and flags unusual patterns.

Whether you’re projecting future royalty streams, checking how Ionis accounts for partner reimbursements, or reviewing CEO pay in the Ionis Pharmaceuticals proxy statement executive compensation, you’ll find every document—10-K, 10-Q, 8-K, S-8 and more—indexed and searchable. Interactive summaries, key metric dashboards, and sentence-level citations let you understand Ionis Pharmaceuticals SEC documents with AI in minutes, not hours. Follow upcoming catalysts with Ionis Pharmaceuticals earnings report filing analysis or set custom alerts for Ionis Pharmaceuticals Form 4 insider transactions real-time; Stock Titan turns regulatory complexity into actionable clarity.

Rhea-AI Summary

JPMorgan Chase Financial Company LLC is offering Auto Callable Accelerated Barrier Notes linked individually to the Nasdaq-100 (NDX), Russell 2000 (RTY) and S&P 500 (SPX) indices. The notes are unsecured, unsubordinated obligations of JPMorgan Chase Financial and are fully and unconditionally guaranteed by JPMorgan Chase & Co. Key commercial terms are still preliminary and will be finalized on or about July 28 2025, with settlement expected on July 31 2025 and maturity on August 2 2028.

  • Automatic call feature: If on any non-final Review Date (July 31 2026 or July 28 2027) the closing level of each index is at or above 100 % of its Initial Value, the notes will be redeemed early for $1,000 plus the applicable Call Premium Amount (≥ 12.55 % or ≥ 25.10 %).
  • Upside participation at maturity: If not called and all three indices finish above their Initial Values on the final Review Date, investors receive 1.50× the percentage gain of the worst-performing index (uncapped).
  • Barrier protection: 70 % of Initial Value for each index. If any index closes below its barrier on the final Review Date, principal is reduced one-for-one with the decline of the worst performer, exposing investors to losses up to 100 %.
  • Indicative economics: Estimated value today is $945.30 per $1,000 note (minimum ≥ $900.00), reflecting selling commissions (≤ $30) and structuring/hedging costs included in the $1,000 issue price.
  • Liquidity & credit: The notes will not be listed; secondary prices depend on JPMS bid. Payment is subject to the credit of both the issuer and guarantor.

Investors forgo periodic coupons and dividends, face potential early redemption that caps upside, and assume index, market-volatility, credit and liquidity risks as detailed in the extensive “Selected Risk Considerations.”

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Rhea-AI Summary

JPMorgan Chase Financial Company LLC is offering Auto Callable Accelerated Barrier Notes linked individually to the Nasdaq-100 (NDX), Russell 2000 (RTY) and S&P 500 (SPX) indices. The notes are unsecured, unsubordinated obligations of JPMorgan Chase Financial and are fully and unconditionally guaranteed by JPMorgan Chase & Co. Key commercial terms are still preliminary and will be finalized on or about July 28 2025, with settlement expected on July 31 2025 and maturity on August 2 2028.

  • Automatic call feature: If on any non-final Review Date (July 31 2026 or July 28 2027) the closing level of each index is at or above 100 % of its Initial Value, the notes will be redeemed early for $1,000 plus the applicable Call Premium Amount (≥ 12.55 % or ≥ 25.10 %).
  • Upside participation at maturity: If not called and all three indices finish above their Initial Values on the final Review Date, investors receive 1.50× the percentage gain of the worst-performing index (uncapped).
  • Barrier protection: 70 % of Initial Value for each index. If any index closes below its barrier on the final Review Date, principal is reduced one-for-one with the decline of the worst performer, exposing investors to losses up to 100 %.
  • Indicative economics: Estimated value today is $945.30 per $1,000 note (minimum ≥ $900.00), reflecting selling commissions (≤ $30) and structuring/hedging costs included in the $1,000 issue price.
  • Liquidity & credit: The notes will not be listed; secondary prices depend on JPMS bid. Payment is subject to the credit of both the issuer and guarantor.

Investors forgo periodic coupons and dividends, face potential early redemption that caps upside, and assume index, market-volatility, credit and liquidity risks as detailed in the extensive “Selected Risk Considerations.”

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Rhea-AI Summary

JPMorgan Chase Financial Company LLC is offering Auto Callable Accelerated Barrier Notes linked individually to the Nasdaq-100 (NDX), Russell 2000 (RTY) and S&P 500 (SPX) indices. The notes are unsecured, unsubordinated obligations of JPMorgan Chase Financial and are fully and unconditionally guaranteed by JPMorgan Chase & Co. Key commercial terms are still preliminary and will be finalized on or about July 28 2025, with settlement expected on July 31 2025 and maturity on August 2 2028.

  • Automatic call feature: If on any non-final Review Date (July 31 2026 or July 28 2027) the closing level of each index is at or above 100 % of its Initial Value, the notes will be redeemed early for $1,000 plus the applicable Call Premium Amount (≥ 12.55 % or ≥ 25.10 %).
  • Upside participation at maturity: If not called and all three indices finish above their Initial Values on the final Review Date, investors receive 1.50× the percentage gain of the worst-performing index (uncapped).
  • Barrier protection: 70 % of Initial Value for each index. If any index closes below its barrier on the final Review Date, principal is reduced one-for-one with the decline of the worst performer, exposing investors to losses up to 100 %.
  • Indicative economics: Estimated value today is $945.30 per $1,000 note (minimum ≥ $900.00), reflecting selling commissions (≤ $30) and structuring/hedging costs included in the $1,000 issue price.
  • Liquidity & credit: The notes will not be listed; secondary prices depend on JPMS bid. Payment is subject to the credit of both the issuer and guarantor.

Investors forgo periodic coupons and dividends, face potential early redemption that caps upside, and assume index, market-volatility, credit and liquidity risks as detailed in the extensive “Selected Risk Considerations.”

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Rhea-AI Summary

Ionis Pharmaceuticals (IONS) filed a Form 4 disclosing routine board compensation for non-employee director Allene M. Diaz on 07/01/2025. She received:

  • 11,518 non-qualified stock options with a strike price of $39.94.
  • 5,220 restricted stock units (RSUs).

Under the company’s Non-Employee Director Compensation Policy, total 2025 equity value was capped at $450,000 (ASC 718 grant-date fair value), so the awards were adjusted downward to stay within that limit.

Both the options and RSUs vest 100 % on the earlier of (i) the first anniversary of the grant or (ii) the next annual shareholder meeting. No shares are currently vested or exercisable.

After the grant, Diaz beneficially owns 11,518 derivative option securities and 9,299 RSUs, all held directly. No open-market purchases or sales occurred, and no cash changed hands; the filing reflects standard equity grants intended to align director incentives with shareholder interests.

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Rhea-AI Summary

Ionis Pharmaceuticals (IONS) filed a Form 4 disclosing routine board compensation for non-employee director Allene M. Diaz on 07/01/2025. She received:

  • 11,518 non-qualified stock options with a strike price of $39.94.
  • 5,220 restricted stock units (RSUs).

Under the company’s Non-Employee Director Compensation Policy, total 2025 equity value was capped at $450,000 (ASC 718 grant-date fair value), so the awards were adjusted downward to stay within that limit.

Both the options and RSUs vest 100 % on the earlier of (i) the first anniversary of the grant or (ii) the next annual shareholder meeting. No shares are currently vested or exercisable.

After the grant, Diaz beneficially owns 11,518 derivative option securities and 9,299 RSUs, all held directly. No open-market purchases or sales occurred, and no cash changed hands; the filing reflects standard equity grants intended to align director incentives with shareholder interests.

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Rhea-AI Summary

Ionis Pharmaceuticals (IONS) filed a Form 4 disclosing routine board compensation for non-employee director Allene M. Diaz on 07/01/2025. She received:

  • 11,518 non-qualified stock options with a strike price of $39.94.
  • 5,220 restricted stock units (RSUs).

Under the company’s Non-Employee Director Compensation Policy, total 2025 equity value was capped at $450,000 (ASC 718 grant-date fair value), so the awards were adjusted downward to stay within that limit.

Both the options and RSUs vest 100 % on the earlier of (i) the first anniversary of the grant or (ii) the next annual shareholder meeting. No shares are currently vested or exercisable.

After the grant, Diaz beneficially owns 11,518 derivative option securities and 9,299 RSUs, all held directly. No open-market purchases or sales occurred, and no cash changed hands; the filing reflects standard equity grants intended to align director incentives with shareholder interests.

Rhea-AI Impact
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Rhea-AI Summary

Ionis Pharmaceuticals (IONS) filed a Form 4 disclosing routine board compensation for non-employee director Allene M. Diaz on 07/01/2025. She received:

  • 11,518 non-qualified stock options with a strike price of $39.94.
  • 5,220 restricted stock units (RSUs).

Under the company’s Non-Employee Director Compensation Policy, total 2025 equity value was capped at $450,000 (ASC 718 grant-date fair value), so the awards were adjusted downward to stay within that limit.

Both the options and RSUs vest 100 % on the earlier of (i) the first anniversary of the grant or (ii) the next annual shareholder meeting. No shares are currently vested or exercisable.

After the grant, Diaz beneficially owns 11,518 derivative option securities and 9,299 RSUs, all held directly. No open-market purchases or sales occurred, and no cash changed hands; the filing reflects standard equity grants intended to align director incentives with shareholder interests.

Rhea-AI Impact
Rhea-AI Sentiment
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Rhea-AI Summary

Ionis Pharmaceuticals (IONS) filed a Form 4 disclosing routine board compensation for non-employee director Allene M. Diaz on 07/01/2025. She received:

  • 11,518 non-qualified stock options with a strike price of $39.94.
  • 5,220 restricted stock units (RSUs).

Under the company’s Non-Employee Director Compensation Policy, total 2025 equity value was capped at $450,000 (ASC 718 grant-date fair value), so the awards were adjusted downward to stay within that limit.

Both the options and RSUs vest 100 % on the earlier of (i) the first anniversary of the grant or (ii) the next annual shareholder meeting. No shares are currently vested or exercisable.

After the grant, Diaz beneficially owns 11,518 derivative option securities and 9,299 RSUs, all held directly. No open-market purchases or sales occurred, and no cash changed hands; the filing reflects standard equity grants intended to align director incentives with shareholder interests.

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Form 4 filing for Apollo Global Management, Inc. (APO): Director Mitra O’Neill (professionally known as Mitra Hormozi) reported the grant of 1,446 restricted stock units (RSUs) on 07/01/2025 under the company’s 2019 Omnibus Equity Incentive Plan. Each RSU converts into one share of APO common stock upon vesting, with settlement deferred until the director leaves the board. Following the award, the director’s direct holdings total 30,344 shares (including 7,049 RSUs already held). In addition, 2,500 shares are indirectly held through an entity controlled by the director’s spouse. No shares were sold, no cash changed hands, and no derivative securities were involved. This filing reflects routine, service-based equity compensation aimed at aligning director interests with shareholders rather than signaling a change in company fundamentals.

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FAQ

What is the current stock price of Ionis Pharmaceuticals (IONS)?

The current stock price of Ionis Pharmaceuticals (IONS) is $42 as of July 15, 2025.

What is the market cap of Ionis Pharmaceuticals (IONS)?

The market cap of Ionis Pharmaceuticals (IONS) is approximately 6.6B.

What is Ionis Pharmaceuticals known for?

Ionis Pharmaceuticals is renowned for developing innovative antisense RNA therapies. Their advanced research platform has enabled them to create novel treatments for complex and serious diseases.

How does Ionis generate revenue?

The company generates revenue through a combination of direct commercialization, licensing agreements, and strategic partnerships with other pharmaceutical firms. This diversified business model supports both independent launches and collaborative projects.

What areas of medicine does Ionis focus on?

Ionis focuses on developing treatments for a range of disease areas including neurology, cardiology, metabolic disorders, and rare genetic diseases. Their innovative approach targets conditions with high unmet medical needs.

How does Ionis maintain its industry leadership?

Through a commitment to scientific excellence and a robust portfolio of patents, Ionis has established a leadership role in antisense technology and RNA-targeted therapies. Strategic collaborations and rigorous clinical trials reinforce their competitive edge.

Can you describe Ionis Pharmaceuticals' research approach?

Ionis employs a sophisticated research platform centered on antisense oligonucleotides and gene editing techniques. This approach allows them to directly target the genetic root causes of diseases and innovate effective treatment strategies.

What role do partnerships play in Ionis' operations?

Partnerships are a crucial element of Ionis' strategy. Collaborations with well-established companies help validate their research, expand market access, and accelerate the development and commercialization of innovative therapies.

How does Ionis ensure the quality of its therapies?

Ionis employs rigorous clinical research and maintains high standards in its drug development processes. Their comprehensive clinical trial programs and extensive patent portfolio exemplify their commitment to quality and safety.

What distinguishes Ionis within the biotechnology sector?

Ionis is distinguished by its pioneering role in RNA-targeted therapies and its proven antisense technology platform. A history of transformative drug launches and ongoing research in cutting-edge therapeutics set it apart in the competitive biotechnology landscape.
Ionis Pharmaceuticals

NASDAQ:IONS

IONS Rankings

IONS Stock Data

6.65B
155.32M
0.83%
105.1%
8.09%
Biotechnology
Pharmaceutical Preparations
Link
United States
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