Director reports Rule 144 sales of common stock

IONS: A Rule 144 notice reports planned and recent sales of Common Stock.

Rhea-AI Filing Summary

IONS: A Rule 144 notice reports planned and recent sales of Common Stock. The record lists 10,837 restricted shares tied to an 04/15/2022 award with a 04/15/2026 date and three reported open-market sales by Joseph Baroldi on 01/30/2026, 03/03/2026, and 04/16/2026.

Key Figures

Restricted shares: 10,837 shares Sale on 01/30/2026: 5,296 shares Sale on 03/03/2026: 4,096 shares +1 more

4 metrics

Restricted shares 10,837 shares Restricted Stock award dated 04/15/2022 with 04/15/2026 date

Sale on 01/30/2026 5,296 shares Joseph Baroldi sale with proceeds $439,694.00

Sale on 03/03/2026 4,096 shares Joseph Baroldi sale with proceeds $325,059.00

Sale on 04/16/2026 5,619 shares Joseph Baroldi sale with proceeds $423,660.00

Key Terms

Restricted Stock, Rule 144, Equity Compensation

3 terms

Restricted Stock financial

"Common Stock | 04/15/2022 | Restricted Stock | Issuer"

Shares granted to an individual that carry limits on transfer or sale until certain conditions are met, such as staying with the company for a set time or hitting performance targets. Think of them as a locked gift that gradually opens; for investors they matter because they affect how many shares may enter the market later, signal management incentives and potential dilution, and reveal confidence in future company performance.

Rule 144 regulatory

"144: Securities To Be Sold"

Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.

Equity Compensation financial

"10837 | 04/15/2026 | Equity Compensation"

Equity compensation is pay given to employees, executives or contractors in the form of company ownership—such as stock, stock options or restricted shares—rather than just cash. It matters to investors because it can align workers' incentives with shareholders (like paying someone in slices of the same pie they help grow), but it also increases the number of shares outstanding and company expenses, affecting ownership percentages and earnings per share.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does the IONS Form 144 report show?

The Form 144 shows a Rule 144 notice for Common Stock and a restricted award of 10,837 shares tied to 04/15/2022 with a date of 04/15/2026. It also lists three completed sales by Joseph Baroldi in 2026.

Who sold shares for IONS and when?

The filing lists sales by Joseph Baroldi on 01/30/2026, 03/03/2026, and 04/16/2026. Each sale is recorded with share counts and gross amounts in the notice’s sales table.

How many shares and proceeds are shown for each sale?

The notice records 5,296 shares for 01/30/2026 with $439,694.00, 4,096 shares for 03/03/2026 with $325,059.00, and 5,619 shares for 04/16/2026 with $423,660.00.

What is the nature of the 10,837 shares listed in the filing?

The 10,837 shares are listed as Restricted Stock from an award dated 04/15/2022 under Equity Compensation, with a relevant date shown as 04/15/2026 in the filing.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 04/28/2026 - 04:12 PM EDT Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001813775
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	Baroldi Joseph
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	1626	116727.00	165192011	04/28/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	04/15/2022	Restricted Stock	Issuer			10837	04/15/2026	Equity Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Joseph Baroldi 2855 GAZELLE COURT CARLSBAD CA 92010	Common Stock	01/30/2026	5296	439694.00
Joseph Baroldi 2855 GAZELLE COURT CARLSBAD CA 92010	Common Stock	03/03/2026	4096	325059.00
Joseph Baroldi 2855 GAZELLE COURT CARLSBAD CA 92010	Common Stock	04/16/2026	5619	423660.00

144: Remarks and Signature

Remarks
Date of Notice	04/28/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	11/25/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ James Weimer, as a duly authorized representative of STIFEL, as attorney-in-fact for Joseph Baroldi
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)