IONS files Form 144 to sell 37,277 common shares

IONS filed a Form 144 notifying proposed sales of Common Stock.

Rhea-AI Filing Summary

IONS filed a Form 144 notifying proposed sales of Common Stock. The notice lists two option-exercise related lots of 4,675 and 32,602 shares scheduled on 03/10/2026 to be sold for cash. The filing also reports a prior sale of 1,823 shares on 01/16/2026 for $138,963 by Kyle Jenne.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does IONS' Form 144 disclose about upcoming share sales?

The filing discloses two option-exercise share lots of 4,675 and 32,602 shares scheduled on 03/10/2026 to be sold for cash. It lists these as issuer-related option exercises.

Who sold shares recently according to the IONS Form 144?

The filing shows that Kyle Jenne sold 1,823 shares on 01/16/2026 for $138,963. This sale is reported under "Securities Sold During The Past 3 Months."

Are the proposed sales in the Form 144 linked to option exercises?

Yes. The filing explicitly lists the two scheduled lots as resulting from Option Exercise with proceeds listed as Cash, indicating shares are to be sold following exercise events on 03/10/2026.

Does the Form 144 state how the shares will be sold (method)?

The excerpt specifies the shares arise from Option Exercise and the consideration as Cash, but it does not describe sale methods like block trades or brokerage transactions in the provided excerpt.

How many total shares are listed for the proposed sale in this filing?

The filing lists two lots totalling 37,277 shares (4,675 and 32,602) scheduled on 03/10/2026. This total is the sum of the two explicitly listed option-exercise lots.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 03/10/2026 - 04:00 PM EDT Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001791857
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	Jenne Kyle
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Director

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	58253	4402296.00	165190000	03/10/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	02/26/2024	Option Exercise	Issuer			4675	03/10/2026	Cash
Common Stock	01/02/2025	Option Exercise	Issuer			32602	03/10/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Kyle Jenne 2855 Gazelle Court Carlsbad CA 92010	Common Stock	01/16/2026	1823	138963.00

144: Remarks and Signature

Remarks
Date of Notice	03/10/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	12/08/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Luca Lotito, as a duly authorized representative of STIFEL, as attorney-in-fact for Kyle Jenne
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)