Ionis Pharmaceuticals (NASDAQ: IONS) Rule 144 notice for 5,619 RSU shares

Rhea-AI Filing Summary

Ionis Pharmaceuticals files a Rule 144 notice to sell 5,619 shares of Common Stock. The filing lists the securities as RSUs granted under the 2011 Equity Incentive Plan with an intended sale date of 04/16/2026. The notice also reports prior open-market sales of 4,096, 5,296, and 6,907 shares on 03/03/2026, 01/30/2026, and 01/16/2026, respectively.

Key Figures

Registered/offered shares: 5,619 shares Prior sale on 03/03/2026: 4,096 shares Prior sale on 01/30/2026: 5,296 shares +4 more

7 metrics

Registered/offered shares 5,619 shares Rule 144 notice dated 04/16/2026

Prior sale on 03/03/2026 4,096 shares Executed through Stifel Nicolaus & Company Inc

Prior sale on 01/30/2026 5,296 shares Executed through Morgan Stanley Smith Barney

Prior sale on 01/16/2026 6,907 shares Executed through Morgan Stanley Smith Barney

Gross proceeds example $325,059.00 Gross proceeds reported for 4,096-share sale on 03/03/2026

Gross proceeds example $439,693.50 Gross proceeds reported for 5,296-share sale on 01/30/2026

Gross proceeds example $523,205.25 Gross proceeds reported for 6,907-share sale on 01/16/2026

Key Terms

Rule 144, RSU, 2011 Equity Incentive Plan

3 terms

Rule 144 regulatory

"Rule 144 notice to sell 5,619 shares of Common Stock"

Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.

RSU financial

"RSUs granted under the 2011 Equity Incentive Plan"

Restricted stock units (RSUs) are a form of company shares given to employees as part of their compensation, usually with certain restrictions or conditions, such as remaining with the company for a set period. When these restrictions lift, employees receive actual shares that they can sell or hold. For investors, RSUs can impact a company's stock supply and reflect the company's commitment to attracting and retaining talent.

2011 Equity Incentive Plan financial

"RSUs granted under the 2011 Equity Incentive Plan"

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Morgan Stanley Smith Barney 1585 Broadway New York NY 10036	5619	423659.67	165192011	04/16/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	04/16/2026	RSUs granted under 2011 Equity Incentive Plan	Ionis Pharmaceuticals			5619	04/15/2026	Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Stifel Nicholaus & Company Inc 501 N Broadway St. Louis MO 63102	Common Stock	03/03/2026	4096	325059.00
Morgan Stanley Smith Barney 1585 Broadway New Yourk NY 10036	Common Stock	01/30/2026	5296	439693.50
Morgan Stanley Smith Barney 1585 Broadway New York NY 10036	Common Stock	01/16/2026	6907	523205.25

144: Remarks and Signature

Remarks

Date of Notice

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

FAQ

What does Ionis Pharmaceuticals' Form 144 for IONS report?

It reports a proposed sale of 5,619 shares of Common Stock as a Rule 144 notice. The shares are described as RSUs under the 2011 Equity Incentive Plan, with an intended sale date of 04/16/2026.

Who appears as broker/dealer on the IONS Form 144 filing?

The filing lists Morgan Stanley Smith Barney (1585 Broadway, New York) and Stifel Nicolaus & Company Inc as brokers. Broker names are provided alongside the reported sale dates and share amounts.

What recent share sales does the IONS filing disclose?

It discloses prior sales of 4,096 shares on 03/03/2026, 5,296 shares on 01/30/2026, and 6,907 shares on 01/16/2026. Each sale is shown with the executing broker and gross proceeds.

Are the shares in the IONS Form 144 from compensation awards?

Yes. The filing specifies the securities as RSUs granted under the 2011 Equity Incentive Plan, indicating the shares originate from compensation-related awards rather than an underwritten offering.