IONS Form 144: 67,386 Shares Notice

IONS submitted a Form 144 notice dated 07/07/2026 reporting an intended sale of 67,386 shares of Common Stock on Nasdaq.

Rhea-AI Filing Summary

IONS submitted a Form 144 notice dated 07/07/2026 reporting an intended sale of 67,386 shares of Common Stock on Nasdaq. The filing lists 20,536 as Owned Shares (01/15/2020) and 46,850 tied to a Stock Option Exercise (01/04/2021), with the broker noted as Stifel Nicolaus.

Insights

Securities Counsel

Routine Rule 144 notice for an intended brokered sale of previously acquired and option-derived shares.

The filing records an intended sale of 67,386 shares via Stifel Nicolaus on 07/07/2026. It distinguishes Owned Shares (20,536) from shares associated with a Stock Option Exercise (46,850), and indicates Cash as the consideration method.

Timing and execution mechanics are governed by Rule 144 conditions and broker handling; subsequent Form 4/Form 5 or a trade confirmation would show whether and when shares were actually sold. Cash‑flow treatment and purchaser identity are not detailed in the excerpt.

Key Figures

Total shares listed for sale: 67,386 shares Owned Shares: 20,536 shares Stock Option Exercise: 46,850 shares

3 metrics

Total shares listed for sale 67,386 shares Form 144 filing dated 07/07/2026

Owned Shares 20,536 shares Owned Shares dated 01/15/2020

Stock Option Exercise 46,850 shares Stock Option Exercise dated 01/04/2021

Key Terms

Form 144, Owned Shares, Stock Option Exercise, Cash

4 terms

Form 144 regulatory

"Filer Information | 144: Filer Information"

Form 144 is a document that investors must file with the government when they plan to sell a large number of shares of a company's stock. It helps ensure transparency so everyone knows how many shares are being sold and when, which can impact the stock's price.

Owned Shares financial

"Common Stock | Owned Shares | 01/15/2020 | 20536"

Stock Option Exercise financial

"Equity Compensation Common Stock | Stock Option Exercise | 01/04/2021 | 46850"

A stock option exercise is the act of using a previously granted right to buy shares of a company's stock at a specific, predetermined price by paying that price and receiving the shares. It matters to investors because exercising changes who owns the shares (which can dilute existing ownership), can trigger taxable events and shift potential gains or losses, and affects voting power and the company’s outstanding share count—like turning a voucher into an actual product that becomes part of circulating supply.

Cash financial

"07/07/2026 | Cash"

FAQ

What does IONS' Form 144 filed on 07/07/2026 report?

The Form 144 reports an intended sale of 67,386 shares of Common Stock through Stifel Nicolaus on 07/07/2026, split between 20,536 owned shares and 46,850 from a stock option exercise.

How many shares in the IONS filing are listed as owned versus option‑derived?

The filing lists 20,536 shares as Owned Shares (01/15/2020) and 46,850 shares associated with a Stock Option Exercise (01/04/2021), totaling 67,386 shares.

Who is the broker handling the IONS sale reported in the Form 144?

The Form 144 identifies Stifel Nicolaus & Company Inc at the St. Louis address as the broker; the filing shows Nasdaq as the market and lists Cash as the consideration method.

Does the Form 144 confirm the shares were sold for IONS?

The Form 144 provides a notice of intended sale of 67,386 shares dated 07/07/2026. It does not confirm settlement; trade execution and proceeds would be shown in subsequent transaction records.

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Available on EDGAR 07/07/2026 - 04:29 PM Accepted by SEC EDGAR 07/07/2026 - 04:28 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001073387
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	BENNETT C FRANK
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	67386	5724724.00	165262556	07/07/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/15/2020	Owned Shares	Issuer			20536	01/15/2020	Equity Compensation
Common Stock	01/04/2021	Stock Option Exercise	Issuer			46850	07/07/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks	Owned Shares are from various restricted stock unit vest events from 1/15/2020 to 1/29/2026
Date of Notice	07/07/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	03/31/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ James Weimer, as a duly authorized representative of STIFEL, as attorney-in-fact for Frank Bennett
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)