Ionis insider plans sale of 44,034 shares

Ionis Pharmaceuticals is the issuer of common stock that a holder plans to sell under Rule 144.

Rhea-AI Filing Summary

Ionis Pharmaceuticals is the issuer of common stock that a holder plans to sell under Rule 144. The notice covers the planned sale of 44,034 shares of common stock through Morgan Stanley Smith Barney on or about 01/16/2026 on the NASDAQ market, with an aggregate market value of $3,357,167.26. These shares were acquired on 01/15/2026 as RSUs granted under the 2011 Equity Incentive Plan, treated as compensation. As context, 161,137,930 shares of this class were outstanding at the time stated.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many Ionis (IONS) shares are covered by this Rule 144 notice?

The notice covers the planned sale of 44,034 shares of Ionis Pharmaceuticals common stock.

What is the market value of the Ionis (IONS) shares to be sold?

The aggregate market value of the shares to be sold is $3,357,167.26, based on the figure stated in the notice.

When were the Ionis (IONS) shares acquired and how?

The shares were acquired on 01/15/2026 as RSUs granted under the 2011 Equity Incentive Plan, characterized as compensation.

When is the approximate sale date for these Ionis (IONS) shares?

The approximate date of sale listed is 01/16/2026, one day after the RSUs were acquired.

Which broker and exchange are involved in this Ionis (IONS) Rule 144 sale?

The planned sale is through Morgan Stanley Smith Barney, with trading on the NASDAQ exchange.

How many Ionis (IONS) common shares were outstanding at the time referenced?

The notice reports 161,137,930 common shares of Ionis Pharmaceuticals outstanding as of the referenced time; this is a baseline figure, not the amount being sold.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 01/16/2026 - 06:44 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001537529
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	Monia Brett P
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer
Relationship to Issuer	Director

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Morgan Stanley Smith Barney 1585 Broadway New York NY 10036	44034	3357167.26	161137930	01/16/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/15/2026	RSUs granted under 2011 Equity Incentive Plan	Ionis Pharmaceuticals			44034	01/15/2026	Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks
Date of Notice	01/16/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	Brett P. Monia
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)