Opus Genetics, Inc. ownership disclosure: Nantahala Capital Management, LLC and related reporting persons report beneficial ownership of 4,839,225 shares of Common Stock as of March 31, 2026. The filing states that 3,157,895 of those shares may be acquired within sixty days through the exercise of convertible securities. Each of Nantahala, Wilmot B. Harkey and Daniel Mack is reported as beneficially owning 6.51% of the outstanding shares, with shared voting and dispositive power over the 4,839,225 shares.
Positive
None.
Negative
None.
Insights
Major shareholder reports shared control of 4.84M shares (6.51%).
The schedule states 4,839,225 shares are held by funds and accounts under Nantahala's control as of March 31, 2026, and that 3,157,895 shares are exercisable within sixty days via convertible securities. The filing attributes shared voting and dispositive power to Nantahala and to Messrs. Harkey and Mack as managing members.
Cash‑flow treatment and any planned dispositions are not described in the excerpt; subsequent filings would state transactions if they occur. Watch later public filings for changes to the reported stake or for Schedule 13D amendments if activist intent arises.
Disclosure aligns with adviser/control person reporting conventions.
The filing is an amended Schedule 13G/A identifying Nantahala as an investment adviser and Messrs. Harkey and Mack as control persons, and it attaches signatures including a Chief Compliance Officer. The statement that shares include convertible securities exercisable within sixty days is a standard beneficial‑ownership qualifier.
Confirmatory items to monitor in future filings include any change from passive 13G status to active 13D status or public trading by the reporting funds. Regulatory follow‑ups would appear in subsequent SEC schedules.
Key Figures
Beneficial ownership:4,839,225 sharesExercisable via convertible securities:3,157,895 sharesPercent of class:6.51%+2 more
5 metrics
Beneficial ownership4,839,225 sharesAs of March 31, 2026
Exercisable via convertible securities3,157,895 sharesMay be acquired within sixty days
Percent of class6.51%Reported percentage for each Reporting Person as of March 31, 2026
Sole voting power0 SharesEach Reporting Person reports no sole voting power
Shared voting/dispositive power4,839,225 SharesShared power reported for Nantahala, Harkey and Mack
"Nantahala may be deemed to be the beneficial owner of 4,839,225 Shares"
A beneficial owner is the person who ultimately owns or controls a financial asset or property, even if their name isn't directly on official documents. Think of it like someone who secretly holds the keys to a safe deposit box—others may appear to have access, but the true owner is the one who benefits from what's inside. Identifying beneficial owners helps ensure transparency and prevent illegal activities like money laundering or fraud.
convertible securitiesfinancial
"Include 3,157,895 Shares which may be acquired by the Reporting Persons within sixty days through the exercise of convertible securities"
Convertible securities are bonds or preferred shares that can be exchanged for a company’s common stock at a predetermined price or under specified conditions. They matter because they combine the steadiness of a loan or fixed dividend with the potential upside of ownership; like a safety‑net that carries a one‑time ticket to become a shareholder, they affect expected returns and can dilute existing stock if converted.
Schedule 13G/Aregulatory
"This as a control person in respect of shares beneficially owned by Nantahala"
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 3)
Opus Genetics, Inc.
(Name of Issuer)
Common Stock, $0.0001 par value per share
(Title of Class of Securities)
67577R102
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
67577R102
1
Names of Reporting Persons
Nantahala Capital Management, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
MASSACHUSETTS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,839,225.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
4,839,225.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
4,839,225.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
6.51 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP Number(s):
67577R102
1
Names of Reporting Persons
Wilmot B. Harkey
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,839,225.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
4,839,225.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
4,839,225.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
6.51 %
12
Type of Reporting Person (See Instructions)
HC
SCHEDULE 13G
CUSIP Number(s):
67577R102
1
Names of Reporting Persons
Daniel Mack
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
4,839,225.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
4,839,225.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
4,839,225.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
6.51 %
12
Type of Reporting Person (See Instructions)
HC
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Opus Genetics, Inc.
(b)
Address of issuer's principal executive offices:
8 DAVIS DRIVE SUITE 220 DURHAM, NORTH CAROLINA, 27713
Item 2.
(a)
Name of person filing:
(1) Nantahala Capital Management, LLC ("Nantahala")
(2) Wilmot B. Harkey
(3) Daniel Mack (together the "Reporting Persons")
(b)
Address or principal business office or, if none, residence:
130 Main St. 2nd Floor, New Canaan, Connecticut 06840
(c)
Citizenship:
(1) Nantahala is a Massachusetts limited liability company.
(2) Each of Messrs. Harkey and Mack is a citizen of the United States of America.
(d)
Title of class of securities:
Common Stock, $0.0001 par value per share
(e)
CUSIP No.:
67577R102
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
As of March 31, 2026, Nantahala may be deemed to be the beneficial owner of 4,839,225 Shares held by funds and separately managed accounts under its control, and as the managing members of Nantahala, each of Messrs. Harkey and Mack may be deemed to be a beneficial owner of those Shares. The 4,839,225 Shares Include 3,157,895 Shares which may be acquired by the Reporting Persons within sixty days through the exercise of convertible securities.
(b)
Percent of class:
As of March 31, 2026, each of the Reporting Persons may be deemed to be the beneficial owner of the following percentage of the total number of Shares outstanding:
(1) Nantahala Capital Management, LLC ("Nantahala") : 6.51%
(2) Wilmot B. Harkey: 6.51%
(3) Daniel Mack: 6.51%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
(1) Nantahala Capital Management, LLC ("Nantahala") : 0 Shares.
(2) Wilmot B. Harkey: 0 Shares.
(3) Daniel Mack: 0 Shares.
(ii) Shared power to vote or to direct the vote:
(1) Nantahala Capital Management, LLC ("Nantahala") : 4,839,225 Shares.
(2) Wilmot B. Harkey: 4,839,225 Shares.
(3) Daniel Mack: 4,839,225 Shares.
(iii) Sole power to dispose or to direct the disposition of:
(1) Nantahala Capital Management, LLC ("Nantahala") : 0 Shares.
(2) Wilmot B. Harkey: 0 Shares.
(3) Daniel Mack: 0 Shares.
(iv) Shared power to dispose or to direct the disposition of:
(1) Nantahala Capital Management, LLC ("Nantahala") : 4,839,225 Shares.
(2) Wilmot B. Harkey: 4,839,225 Shares.
(3) Daniel Mack: 4,839,225 Shares.
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.
Each of Messrs. Harkey and Mack is filing this Schedule 13G as a control person in respect of shares beneficially owned by Nantahala, an investment adviser as described in ss. 240.13d-1(b)(1)(ii)(E). See Item 4(a).
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
What stake does Nantahala Capital report in Opus Genetics (IRD)?
Nantahala reports beneficial ownership of 4,839,225 shares as of March 31, 2026. The filing states that amount represents 6.51% of the outstanding Common Stock.
How many of the reported Opus Genetics shares are exercisable within 60 days?
3,157,895 shares are identified as potentially acquirable within sixty days through the exercise of convertible securities, according to the Schedule 13G/A filed by the reporting persons.
Do Messrs. Harkey and Mack report voting control over the shares?
Yes. The filing states each reporting person has shared voting power and shared dispositive power over 4,839,225 shares; none report sole voting or sole dispositive power.
What is the filing date and form type for this ownership disclosure?
The document is an Amendment No. 3 to a Schedule 13G/A signed on May 15, 2026 and reports ownership figures as of March 31, 2026.
Who filed the Schedule 13G/A for Opus Genetics (IRD)?
The filing lists Nantahala Capital Management, LLC; Wilmot B. Harkey; and Daniel Mack as the reporting persons, with an address at 130 Main St., New Canaan, Connecticut.
