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Dr. Sudha Rao joins Kazia Therapeutics (NASDAQ: KZIA) as part-time CSO

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(Neutral)
Form Type
6-K

Rhea-AI Filing Summary

Kazia Therapeutics Limited has appointed Dr. Sudha Rao as Chief Scientific Officer under a new employment agreement. Effective April 13, 2026, she will serve part-time, three days per week, with an annual base salary of AUD$325,000 and a target annual bonus equal to 40% of base salary.

The agreement includes options to acquire 250,000 American Depositary Shares, with one-third vesting at commencement and the remainder vesting in equal tranches on the first and second anniversaries, subject to board approval. Dr. Rao will continue her role at QIMR Berghofer Medical Research Institute while leading Kazia’s scientific and R&D strategy.

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Base salary AUD$325,000 per year Annual base salary for CSO role under Employment Agreement
Target bonus 40% of base salary Annual performance bonus target for CSO
Equity grant 250,000 ADS options Stock options for Chief Scientific Officer, subject to board approval
Work schedule 3 days per week Part-time basis for Chief Scientific Officer role
Agreement date April 10, 2026 Date Employment Agreement with Dr. Sudha Rao was entered into
Commencement date April 13, 2026 Effective date for Dr. Rao’s service as Chief Scientific Officer
Press release date April 15, 2026 Date of press release announcing CSO appointment
American Depositary Shares financial
"provides for a grant of options to acquire 250,000 American Depositary Shares"
American depositary shares (ADSs) are a way for investors in the United States to buy shares of foreign companies without dealing with international markets directly. They represent ownership in a foreign company's stock and are traded on U.S. stock exchanges, making it easier for American investors to buy, sell, and own parts of companies from around the world.
performance bonus financial
"eligible to receive an annual performance bonus with a target of 40% of her base salary"
Orphan Drug Designation regulatory
"Paxalisib was granted Orphan Drug Designation for glioblastoma by the U.S. Food and Drug Administration"
Orphan drug designation is a special status given to medicines developed to treat rare diseases affecting only a small number of people. This status often provides benefits like faster approval processes and financial incentives, making it more attractive for companies to develop these drugs. For investors, it signals potential for exclusive market rights and reduced competition, which can impact the drug’s profitability.
Fast Track Designation regulatory
"Paxalisib was granted Orphan Drug Designation for glioblastoma... and Fast Track Designation (FTD) for glioblastoma"
Fast track designation is a status the U.S. Food and Drug Administration grants to drugs intended to treat serious conditions and address an unmet medical need. It gives the developer more frequent communication with the FDA and can allow parts of the application to be reviewed on a rolling basis, and it may pave the way to priority review or accelerated approval. It can shorten development timelines, though it does not guarantee approval.
Rare Pediatric Disease Designation regulatory
"paxalisib was granted Rare Pediatric Disease Designation and Orphan Drug Designation by the FDA"
A rare pediatric disease designation is an official regulatory status given to a drug or therapy that targets a serious or life‑threatening condition primarily affecting children and is uncommon in the population. It matters to investors because the status often brings financial and development perks — such as tax credits, reduced fees, faster review and periods of market protection — which can lower costs, speed approval and improve the commercial outlook; think of it as a VIP pass that makes bringing a scarce, child‑focused treatment to market easier and potentially more profitable.
epigenetic therapeutics medical
"has advanced first-in-class epigenetic therapeutics from discovery through IND-enabling studies"

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What executive change did Kazia Therapeutics (KZIA) announce in this 6-K?

Kazia Therapeutics appointed Dr. Sudha Rao as Chief Scientific Officer. She will lead research and development and platform strategy while serving part-time and continuing her role at QIMR Berghofer Medical Research Institute, strengthening the company’s scientific leadership in oncology.

What are the key terms of Dr. Sudha Rao’s employment with Kazia Therapeutics (KZIA)?

Dr. Rao will serve as part-time Chief Scientific Officer three days per week with an annual base salary of AUD$325,000 and an annual performance bonus targeted at 40% of base salary, subject to performance objectives set by Kazia’s board of directors.

What equity compensation will Dr. Sudha Rao receive from Kazia Therapeutics (KZIA)?

Dr. Rao’s agreement includes options to acquire 250,000 American Depositary Shares of Kazia, subject to board approval. One-third vests at employment commencement, and the remaining two-thirds vest in two equal annual installments on the first and second anniversaries of her start date.

Can Kazia Therapeutics (KZIA) Chief Scientific Officer Dr. Sudha Rao hold other roles?

Yes. The employment agreement explicitly permits Dr. Sudha Rao to maintain concurrent employment with QIMR Berghofer Medical Research Institute while serving as part-time Chief Scientific Officer at Kazia, allowing her to continue leading her academic research laboratory.

How does Kazia Therapeutics (KZIA) use this 6-K in its Form F-3 registrations?

Kazia incorporates by reference the information in this report, including the employment agreement and press release, into its Form F-3 registration statements, excluding quotes from its CEO and certain prior exhibit materials related to a separate director departure disclosure.

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 

FORM 6-K

 

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16

UNDER THE SECURITIES EXCHANGE ACT OF 1934

 

For the Month of April 2026

 

Commission File Number: 000-29962

 

Kazia Therapeutics Limited. 

(Exact Name of Registrant as Specified in Its Charter)

 

Three International Towers Level 24 300 Barangaroo Avenue Sydney NSW 2000

(Address of principal executive offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

 

Form 20-F ☒       Form 40-F ☐

 

 

  

 

INFORMATION CONTAINED IN THIS FORM 6-K REPORT

 

Entry into Employment Agreement with Chief Scientific Officer

 

This report on Form 6-K (the “Report”) contains information regarding the entry into a material employment agreement by Kazia Therapeutics Limited (the “Company”). On April 10, 2026, the Company entered into an Employment Agreement (the “Agreement”) with Dr. Sudha Rao, pursuant to which Dr. Rao will serve as the Company’s Chief Scientific Officer (“CSO”), effective April 13, 2026.

 

Under the terms of the Agreement, Dr. Rao will serve as Chief Scientific Officer on a part-time basis (three days per week) and will receive an annual base salary of AUD$325,000. Dr. Rao is eligible to receive an annual performance bonus with a target of 40% of her base salary, subject to the achievement of performance objectives determined by the Company’s Board of Directors. The Agreement also provides for a grant of options to acquire 250,000 American Depositary Shares (“ADS”) of the Company, subject to approval by the Company’s Board of Directors, with one-third vesting upon commencement of employment and the remaining two-thirds vesting in two equal annual installments on the first and second anniversaries of the commencement date. The Agreement permits Dr. Rao to maintain concurrent employment with QIMR Berghofer Medical Research Institute.

 

The foregoing description of the Agreement does not purport to be complete and is qualified in its entirety by reference to the full text of the Agreement, which is filed as Exhibit 10.1 to this Report and is incorporated herein by reference.

  

Press Release

 

The Company is furnishing with this Report on Form 6-K a press release announcing the appointment of Dr. Sudha Rao as Chief Scientific Officer, dated April 15, 2026, as Exhibit 99.1.

 

Incorporation by Reference

 

The Company hereby incorporates by reference the information contained herein, including Exhibits 10.1 and 99.1, except for the quotes of Dr. John Friend, Chief Executive Officer of the Company, contained in Exhibit 99.1, into the Company’s registration statements on Form F-3 (File Nos. 333-276091, 333-281937 and 333-294392).

 

The Company hereby incorporates by reference the information contained under the heading “Departure of Director” in the Company’s report on Form 6-K furnished with the Securities and Exchange Commission on March 31, 2026, but excluding any other information contained in such report, including Exhibits 99.1 and 99.2 thereto, into the Company’s registration statements on Form F-3 (File Nos. 333-276091, 333-281937 and 333-294392).

 

EXHIBIT INDEX

  

Exhibit   Description
10.1   Employment Agreement, dated as of April 10, 2026, by and between Kazia Therapeutics Limited and Dr. Sudha Rao.
99.1   Press Release dated April 15, 2026.

 

1

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

  Kazia Therapeutics Limited.
     
  By: /s/ John Friend
  Name:  John Friend
  Title: Chief Executive Officer
     
Date: April 15, 2026    

 

2

Exhibit 99.1

 

Kazia Therapeutics Strengthens Scientific Leadership with Appointment of Dr. Sudha Rao as Chief Scientific Officer to Lead Next-Generation Oncology Platform

 

Sydney, Australia – April 15, 2026 – Kazia Therapeutics (NASDAQ: KZIA), a clinical-stage oncology company developing differentiated therapies for cancers with high unmet need, today announced the appointment of Dr. Sudha Rao as Chief Scientific Officer (CSO).

 

Dr. Rao is the scientific originator of the epigenetic framework underlying paxalisib and a pioneer in next-generation therapeutic platforms, including PD-L1 protein degradation and SETDB1-targeted chromatin modulation. Her appointment brings deep expertise in translational epigenetics, AI-guided epi-drug discovery capability, liquid and spatial epigenetic clinical biomarker precision medicine platforms, and early clinical development into Kazia’s executive leadership as the Company advances its integrated oncology platform strategy.

 

Dr. Rao is a highly accomplished translational scientist and biotech executive with more than 20 years of experience spanning pharmaceutical R&D, biotechnology, and early clinical development. She currently holds a professorial appointment and leads the Gene Regulation and Translational Medicine Laboratory at QIMR Berghofer Medical Research Institute and previously held senior scientific roles at Sanofi/Rhône-Poulenc in the UK, where she contributed to one of the earliest clinical genomics platforms.

 

She is the founder and former Chief Scientific Officer of EpiAxis Therapeutics and has advanced first-in-class epigenetic therapeutics from discovery through IND-enabling studies and into early clinical trials, including the first Phase 1b study of an LSD1 inhibitor in metastatic breast cancer. Dr. Rao is lead inventor on 39 international patents and has authored numerous high-impact publications in journals including Science, Nature, and Immunity.

 

At Kazia, Dr. Rao will lead all research and development activities, advancing the Company’s pipeline and expanding its next-generation platform capabilities, including:

 

Paxalisib, a brain-penetrant dual PI3K/mTOR inhibitor being developed across oncology indications, including advanced breast cancer;

 

NDL2, a novel PD-L1 protein degrader platform designed to target intracellular and nuclear PD-L1 biology; and

 

MSETC, a first-in-class SETDB1-targeted epigenetic program aimed at reversing immune evasion at the chromatin level.

 

Her scientific work has been central to advancing the concept of PI3K/mTOR inhibition as a driver of epigenetic reprogramming, forming the foundation of Kazia’s strategy to move beyond pathway inhibition toward therapeutic control of cancer’s regulatory drivers.

 

Dr. John Friend, CEO of Kazia Therapeutics, commented: “Dr. Rao is a leading translational epigenetics scientist, a breast cancer researcher, and the lead inventor behind the intellectual property linking PI3K/mTOR inhibition to epigenetic regulation. As the architect of much of our platform, including paxalisib, NDL2, and MSETC, her appointment allows us to immediately strengthen execution while advancing a more integrated, platform-driven oncology strategy.”

 

“I am excited by the opportunity to advance a next-generation oncology platform at Kazia. PI3K/mTOR is a key driver of tumour growth and a master regulator of epigenetic programs that shape tumour behaviour, the tumour microenvironment (TME), and immune evasion,” stated Dr. Rao. “We are building a platform focused on precision targeting and precision medicine, integrating spatial and liquid epigenomics and AI-driven drug discovery to accelerate novel therapies. This includes paxalisib alongside emerging programs such as the PD-L1 degrader and SETDB1-targeting approaches. We aim to enable patient selection, real-time target engagement, and a scalable pipeline with clear clinical translation.”

 

Dr. Rao will also play a key role in advancing Kazia’s biomarker strategy, external collaborations, scientific publications, and strategic partnerships, while continuing to expand the Company’s platform and pipeline.

 

 

 

 

About Kazia

 

Kazia Therapeutics Limited (NASDAQ: KZIA) is an oncology-focused drug development company, based in Sydney, Australia. Our lead program is paxalisib, an investigational brain penetrant inhibitor of the PI3K / Akt / mTOR pathway, which is being developed to treat multiple forms of cancer. Licensed from Genentech in late 2016, paxalisib is or has been the subject of ten clinical trials in this disease. A completed Phase 2/3 study in glioblastoma (GBM-Agile) was reported in 2024, and discussions are ongoing for designing and executing a pivotal registrational study in pursuit of a standard approval. Other clinical trials involving paxalisib are ongoing in advanced breast cancer, brain metastases, diffuse midline gliomas, and primary central nervous system lymphoma, with several of these trials having reported encouraging interim data. Paxalisib was granted Orphan Drug Designation for glioblastoma by the U.S. Food and Drug Administration (FDA) in February 2018, and Fast Track Designation (FTD) for glioblastoma by the FDA in August 2020. Paxalisib was also granted FTD in July 2023 for the treatment of solid tumor brain metastases harboring PI3K pathway mutations in combination with radiation therapy. In addition, paxalisib was granted Rare Pediatric Disease Designation and Orphan Drug Designation by the FDA for diffuse intrinsic pontine glioma in August 2020, and for atypical teratoid / rhabdoid tumors in June 2022 and July 2022, respectively. Kazia is also developing EVT801, a small molecule inhibitor of VEGFR3, which was licensed from Evotec SE in April 2021. In addition to its clinical-stage programs, Kazia is advancing NDL2, a potentially first-in-class nuclear PD-L1 protein degrader program targeting a newly identified mechanism of immunotherapy resistance and metastatic progression, currently in preclinical development. For more information, please visit www.kaziatherapeutics.com or follow us on X @KaziaTx.

 

Forward Looking Statements

 

This announcement may contain forward-looking statements, which can generally be identified as such by the use of words such as “may,” “will,” “estimate,” “future,” “forward,” “anticipate,” or other similar words. Any statement describing Kazia’s future plans, strategies, intentions, expectations, objectives, goals or prospects, and other statements that are not historical facts, are also forward-looking statements, including, but not limited to, statements regarding: the anticipated contributions of Dr. Sudha Rao as Chief Scientific Officer; expectations regarding Dr. Rao’s leadership of Kazia’s research and development activities; the potential of Kazia’s three-platform oncology strategy, including paxalisib, NDL2, and MSETC; expectations regarding the advancement of Kazia’s pipeline and platform capabilities; the potential of paxalisib, including in advanced breast cancer and other oncology indications; the potential of NDL2 as a PD-L1 protein degrader platform; the potential of MSETC as a SETDB1-targeted epigenetic program; expectations regarding Kazia’s biomarker strategy, AI-driven drug discovery, and precision medicine capabilities; and Kazia’s broader pipeline strategy and anticipated benefits of its integrated platform approach. Such statements are based on Kazia’s current expectations and projections about future events and future trends affecting its business and are subject to certain risks and uncertainties that could cause actual results to differ materially from those anticipated in the forward-looking statements, including risks and uncertainties associated with: the ability to attract and retain key personnel, including Dr. Rao; the development of early-stage therapeutic programs; the risk that preclinical results may not be predictive of clinical results; risks related to regulatory approvals; risks related to Kazia’s reliance on third-party collaborators; risks related to intellectual property protection; risks related to the impact of global economic conditions; and risks related to Kazia’s ability to maintain compliance with the applicable NASDAQ continued listing requirements and standards. These and other risks and uncertainties are described more fully in Kazia’s Annual Report on Form 20-F filed with the SEC, and in subsequent filings with the United States Securities and Exchange Commission. Kazia undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events, or otherwise, except as required under applicable law. You should not place undue reliance on these forward-looking statements, which apply only as of the date of this announcement.

 

 

 

Filing Exhibits & Attachments

2 documents