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Lantheus (NASDAQ: LNTH) posts Q1 2026 results and secures FDA wins

Filing Impact
(High)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Lantheus Holdings reported first quarter 2026 revenue of $377.3 million, up 1.2% from a year earlier. GAAP diluted EPS rose to $1.80 from $1.02, helped by a $59.3 million gain on the sale of its SPECT business, while adjusted diluted EPS slipped to $1.46 from $1.53.

PYLARIFY sales were $240.9 million, down 6.5%, DEFINITY grew 6.8% to $84.6 million, and Neuraceq contributed $35.4 million. Operating income declined 20.3% to $81.3 million, but free cash flow increased to $121.9 million, and cash reached $498.6 million.

The company received FDA approval for its new PYLARIFY (piflufolastat F18) formulation, with a phased launch planned starting in the fourth quarter of 2026, and FDA tentative approval for PNT2003, a radioequivalent to Lutetium Lu 177 Dotatate. The FDA also extended the PDUFA date for LNTH‑2501 to June 29, 2026. Lantheus reaffirmed full‑year 2026 guidance for revenue of $1.4–$1.45 billion and adjusted diluted EPS of $5.00–$5.25.

Positive

  • Multiple regulatory milestones: FDA approval for the new PYLARIFY (piflufolastat F18) formulation and FDA tentative approval for PNT2003, plus a defined PDUFA date for LNTH‑2501, advance Lantheus’s radiopharmaceutical portfolio and support its longer-term growth strategy.
  • Strong profitability and cash generation: Q1 2026 GAAP net income rose 62.3% to $118.4 million, free cash flow reached $121.9 million, cash increased to $498.6 million, and the company reaffirmed 2026 revenue and adjusted EPS guidance.

Negative

  • Underlying margin pressure: Despite higher GAAP earnings, operating income declined 20.3% to $81.3 million, adjusted operating margin fell from 38.7% to 34.2%, and adjusted net income decreased 12.5%, indicating softer core profitability.
  • PYLARIFY sales decline: Revenue from PYLARIFY, the company’s key oncology product, fell 6.5% year over year to $240.9 million in Q1 2026, creating a headwind for overall growth.

Insights

Solid cash generation and key FDA wins offset softer core growth.

Lantheus delivered modest Q1 2026 revenue growth of $377.3M (+1.2%), while GAAP EPS jumped to $1.80 mainly from a $59.3M gain on the SPECT divestiture. Core performance was weaker, with operating income down 20.3% and adjusted EPS dipping to $1.46.

Product trends were mixed: PYLARIFY sales fell 6.5% to $240.9M, but DEFINITY grew 6.8% to $84.6M and Neuraceq added $35.4M of neurology revenue. Free cash flow improved to $121.9M, and cash rose to $498.6M, giving meaningful balance sheet flexibility.

Strategically, FDA approval of the new PYLARIFY (piflufolastat F18) formulation and tentative approval of PNT2003 expand the future portfolio, while the LNTH‑2501 PDUFA extension to June 29, 2026 reflects additional manufacturing review rather than efficacy or safety concerns. Reaffirmed 2026 guidance of $1.4–$1.45B revenue and $5.00–$5.25 adjusted EPS suggests management still expects growth to accelerate beyond near‑term product mix headwinds.

Item 0.07 Item 0.07
Item 0.10 Item 0.10
Item 2.02 Results of Operations and Financial Condition Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Q1 2026 Revenue $377.3 million Worldwide revenue, three months ended March 31, 2026; up 1.2% year over year
GAAP diluted EPS $1.80 per share Three months ended March 31, 2026; up 76.5% from $1.02 in Q1 2025
Adjusted diluted EPS $1.46 per share Non-GAAP, Q1 2026 vs $1.53 in Q1 2025; down 4.6%
PYLARIFY revenue $240.9 million Oncology product sales in Q1 2026; down 6.5% year over year
DEFINITY revenue $84.6 million Cardiology product sales in Q1 2026; up 6.8% year over year
Free cash flow $121.9 million Three months ended March 31, 2026; up from $98.8 million in Q1 2025
Cash and equivalents $498.6 million Balance as of March 31, 2026, including $31.4 million SPECT sale proceeds
2026 revenue guidance $1.4–$1.45 billion Full-year 2026 guidance reaffirmed on May 7, 2026
PYLARIFY (piflufolastat F18) medical
"Received FDA approval for PYLARIFY (piflufolastat F18), a new formulation of PYLARIFY®"
PDUFA date regulatory
"The FDA extended the PDUFA date for LNTH‑2501(Ga 68 edotreotide)... to June 29, 2026"
PDUFA date is the deadline the U.S. Food and Drug Administration sets to complete its review of a drug or biologic application and decide whether to approve it. Investors watch it like a court verdict date: the decision can unlock sales and growth if approved or sharply reduce expected value if denied, so markets often move significantly as the date approaches or when the outcome is announced.
tentative approval regulatory
"Achieved FDA tentative approval for PNT2003, which upon full approval would be the first radioequivalent"
free cash flow financial
"Net cash provided by operating activities and free cash flow were $125.1 million and $121.9 million"
Free cash flow is the amount of money a company has left over after paying all its expenses and investing in its business, like buying equipment or updating facilities. It shows how much cash is available to reward shareholders, pay down debt, or save for future growth. This helps investors understand if a company is financially healthy and able to grow.
adjusted operating income financial
"Adjusted operating income (non-GAAP) decreased 10.5% to $129.1 million"
Adjusted operating income is a company's profit from its main activities, excluding certain one-time or unusual costs and gains. It helps investors see how well the business is performing in its normal operations, without distractions from rare events or expenses. This way, they get a clearer picture of the company’s true profitability.
Hatch‑Waxman stay regulatory
"launch timing will consider... the expiration of the 30‑month Hatch‑Waxman stay"
Revenue $377.3 million 1.2% YoY
GAAP diluted EPS $1.80 76.5% YoY
Adjusted diluted EPS $1.46 -4.6% YoY
Guidance

Reaffirmed full-year 2026 revenue guidance of $1.4–$1.45 billion and adjusted fully diluted EPS of $5.00–$5.25.

0001521036false00015210362026-05-072026-05-07

 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

 

FORM 8-K

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): May 07, 2026

 

 

LANTHEUS HOLDINGS, INC.

(Exact name of Registrant as Specified in Its Charter)

 

 

Delaware

001-36569

35-2318913

(State or Other Jurisdiction
of Incorporation)

(Commission File Number)

(IRS Employer
Identification No.)

 

 

 

 

 

201 Burlington Road

South Building

 

Bedford, Massachusetts

 

01730

(Address of Principal Executive Offices)

 

(Zip Code)

 

Registrant’s Telephone Number, Including Area Code: (978) 671-8001

 

Not Applicable

(Former Name or Former Address, if Changed Since Last Report)

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:


Title of each class

 

Trading
Symbol(s)

 


Name of each exchange on which registered

Common stock, par value $0.01 per share

 

LNTH

 

The Nasdaq Global Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

 


Item 2.02 Results of Operations and Financial Condition.

On May 7, 2026, Lantheus Holdings, Inc. (the “Company”) announced via press release its financial results as of and for the three months ended March 31, 2026. A copy of that press release is being furnished as Exhibit 99.1 and is hereby incorporated by reference.

The information furnished pursuant to this Item 2.02, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities under that Section and shall not be deemed to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended (the “Securities Act”), or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

Exhibit No.

Description

99.1*

Press release of Lantheus Holdings, Inc. dated May 7, 2026, entitled “Lantheus Reports First Quarter 2026 Financial Results and Provides Business Update”

 

 

 

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

* Exhibits 99.1 attached hereto are being furnished and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act, as amended, or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.

 


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

LANTHEUS HOLDINGS, INC.

By:

/s/ Daniel M. Niedzwiecki

Name:

Daniel M. Niedzwiecki

Title:

Chief Administrative Officer and General Counsel

Date: May 7, 2026

 


 

Exhibit 99.1

img66337839_0.jpg

 

 

Lantheus Reports First Quarter 2026 Financial Results and Provides Business Update

 

Strong start to the year with worldwide revenue of $377.3 million in the first quarter 2026
GAAP fully diluted earnings per share of $1.80, compared to $1.02 in the first quarter of 2025
Adjusted fully diluted earnings per share of $1.46, compared to $1.53 in the first quarter of 2025
FDA approves PYLARIFY TruVuTM (piflufolastat F18); phased geographic launch planned to begin in the fourth quarter of 2026
FDA tentative approval for Lutetium Lu 177 Dotatate (PNT2003); expected to be the first radioequivalent for the treatment of gastroenteropancreatic neuroendocrine tumors
Reaffirmed previously issued corporate guidance for full year 2026 revenue and adjusted fully diluted earnings per share

BEDFORD, Mass., May 7, 2026 (GLOBE NEWSWIRE) -- Lantheus Holdings, Inc. (Lantheus or the Company) (NASDAQ: LNTH), the leading radiopharmaceutical-focused company committed to enabling clinicians to Find, Fight and Follow disease to deliver better patient outcomes, today reported financial results for its first quarter ended March 31, 2026.

“Our first quarter results demonstrate disciplined execution across the business, with strong performance from PYLARIFY, Neuraceq, and DEFINITY, and continued progress against the priorities that underpin our long-term strategy,” said Mary Anne Heino, Chief Executive Officer of Lantheus. “During the quarter, we secured FDA approval for PYLARIFY TruVu and achieved tentative approval for PNT2003. For the remainder of 2026, we are focused on sustaining our leadership in PSMA PET as we prepare for the PYLARIFY TruVu conversion later this year, expanding our Alzheimer’s imaging portfolio, and advancing our prioritized pipeline. At the same time, we will remain disciplined in our capital deployment, prioritizing radiodiagnostics while evaluating the best path to maximize value from our radiotherapeutic assets – all as we lay the groundwork for growth acceleration beginning in 2027.”

Summary Financial Results

 

 

Three Months Ended
March 31,

 

(in millions, except per share data - unaudited)

 

2026

 

 

2025

 

 

% Change

 

Worldwide revenue

 

$

377.3

 

 

$

372.8

 

 

 

1.2

%

GAAP net income

 

$

118.4

 

 

$

72.9

 

 

 

62.3

%

GAAP fully diluted earnings per share

 

$

1.80

 

 

$

1.02

 

 

 

76.5

%

Adjusted net income (non-GAAP)

 

$

95.8

 

 

$

109.5

 

 

 

(12.5

%)

Adjusted fully diluted earnings per share (non-GAAP)

 

$

1.46

 

 

$

1.53

 

 

 

(4.6

%)

First Quarter 2026

Worldwide revenue increased 1.2% to $377.3 million compared to the same period in 2025.
Sales of PYLARIFY were $240.9 million, a decrease of 6.5%.
Sales of Neuraceq were $35.4 million.
Sales of DEFINITY were $84.6 million, an increase of 6.8%.
Operating income decreased 20.3% to $81.3 million. Adjusted operating income (non-GAAP) decreased 10.5% to $129.1 million.

Page 1 of 11


 

Fully diluted earnings per share increased 76.5% to $1.80, compared to fully diluted earnings per share of $1.02 in the prior year period. Adjusted fully diluted earnings per share (non-GAAP) decreased 4.6% to $1.46, compared to $1.53 in the prior year period.
Net cash provided by operating activities and free cash flow were $125.1 million and $121.9 million, respectively.

Balance Sheet

At March 31, 2026, the Company's cash and cash equivalents were $498.6 million, including proceeds of $31.4 million from the sale of the Company’s single-photon emission computerized tomography (“SPECT”) business to SHINE Technologies, LLC (“SHINE”) on January 1, 2026, compared to $359.1 million at December 31, 2025.
The Company currently has access to up to $750.0 million from a revolving line of credit.

Recent Business Highlights

Received FDA approval for PYLARIFY TruVuTM (piflufolastat F18), a new formulation of PYLARIFY®, the Company’s market‑leading PSMA PET imaging agent, designed to enhance manufacturing efficiency and supply flexibility; a phased geographic commercial launch is planned to begin in the fourth quarter of 2026 to align with coding, coverage, payment, and customer and PMF readiness.
Completed the divestiture of the legacy SPECT business to SHINE (effective January 1, 2026), a decisive action taken to focus on PET radiodiagnostics and simplify the Company’s operating model. 
Achieved FDA tentative approval for PNT2003, which upon full approval would be the first radioequivalent to Lutetium Lu 177 Dotatate for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP‑NETs); launch timing will consider the following factors: the timing of FDA approval, the expiration of the 30‑month Hatch‑Waxman stay and disposition of the related legal proceedings, as well as manufacturing and commercial strategy to ensure launch success.
The FDA extended the PDUFA date for LNTH‑2501(Ga 68 edotreotide), the Company’s PET diagnostic imaging kit for somatostatin receptor‑positive neuroendocrine tumors (NETs), by three months to June 29, 2026, to allow additional time to review manufacturing‑related information. This standard review extension is not related to the efficacy or safety data of LNTH-2501.

Full Year 2026 Financial Guidance

 

 

Guidance Issued May 7, 2026

 

Guidance Issued February 26, 2026

FY 2026 Revenue

 

$1.4 billion - $1.45 billion

 

$1.4 billion - $1.45 billion

FY 2026 Adjusted fully diluted EPS

 

$5.00 - $5.25

 

$5.00 - $5.25

On a forward-looking basis, the Company does not provide GAAP income per common share guidance or a reconciliation of GAAP income per common share to adjusted fully diluted EPS because the Company is unable to predict with reasonable certainty business development and acquisition related expenses, purchase accounting fair value adjustments, and any one-time, non-recurring charges. These items are uncertain, depend on various factors, and could be material to results computed in accordance with GAAP. As a result, it is the Company’s view that a quantitative reconciliation of adjusted fully diluted EPS on a forward-looking basis is not available without unreasonable effort.

Conference Call and Webcast

As previously announced, the Company will host a conference call and webcast on Thursday, May 7, 2026, at 8:00 a.m. ET. To access the conference call or webcast, participants should register online at https://investor.lantheus.com/news-events/calendar-of-events.

A replay will be available approximately two hours after completion of the webcast and will be archived on the same web page for at least 30 days.

The conference call will include a discussion of non-GAAP financial measures. Reference is made to the most directly comparable GAAP financial measures, the reconciliation of the differences between the two financial measures, and the other information included in this press release, our Form 8-K filed with the SEC today, or otherwise available in the Investor Relations section of our website located at www.lantheus.com.

Page 2 of 11


 

The conference call may include forward-looking statements. See the cautionary information about forward-looking statements in the safe-harbor section of this press release.

About Lantheus

Lantheus is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Germany, Switzerland, Sweden and the United Kingdom, Lantheus has been providing radiopharmaceutical solutions for 70 years. For more information, visit www.lantheus.com.

Internet Posting of Information

The Company routinely posts information that may be important to investors in the “Investors” section of its website at www.lantheus.com. The Company encourages investors and potential investors to consult its website regularly for important information about the Company.

Non-GAAP Financial Measures

The Company uses non-GAAP financial measures, such as adjusted net income and its line components; adjusted fully diluted net income per share; adjusted operating income, and free cash flow. The Company’s management believes that the presentation of these measures provides useful information to investors. These measures may assist investors in evaluating the Company’s operations, period over period. However, these measures may exclude items that may be highly variable, difficult to predict and of a size that could have a substantial impact on the Company’s reported results of operations for a particular period. Management uses these and other non-GAAP measures internally for evaluation of the performance of the business, including the evaluation of results relative to employee performance compensation targets. Investors should consider these non-GAAP measures only as a supplement to, not as a substitute for or as superior to, measures of financial performance prepared in accordance with GAAP.

Page 3 of 11


 

Safe Harbor for Forward-Looking and Cautionary Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, that are subject to risks and uncertainties and are made pursuant to the safe harbor provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements may be identified by their use of terms such as “advance,” “believe,” “continue,” “could,” “driving,” “expect,” “guidance,” “maintain,” “may,” “on track,” “plan,” “potential,” “predict,” “progress,” “should,” “target,” “will,” “would” and other similar terms. Such forward-looking statements include our guidance for the fiscal year 2026 and our plans to successfully execute on the commercialization of marketed products, ensure launch readiness for new products, advance a focused late-stage pipeline, and allocate capital thoughtfully, and our focus mainly on our radiodiagnostic business and pursuing value-maximizing alternatives for our radiotherapeutic assets, and are based upon current plans, estimates and expectations that are subject to risks and uncertainties that could cause actual results to materially differ from those described in the forward-looking statements. The inclusion of forward-looking statements should not be regarded as a representation that such plans, estimates and expectations will be achieved. Readers are cautioned not to place undue reliance on the forward-looking statements contained herein, which speak only as of the date hereof. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by law. Risks and uncertainties that could cause our actual results to materially differ from those described in the forward-looking statements include: (i) continued market expansion, penetration and reimbursement for our established commercial products, particularly PYLARIFY, DEFINITY and Neuraceq, in a competitive environment and our ability to clinically and commercially differentiate our products; (ii) our ability to complete the technology transfer across our positron emission tomography (“PET”) manufacturing facilities (“PMF”) network for PYLARIFY TruVu, the new formulation of our F-18 prostate-specific membrane antigen (“PSMA”) PET imaging agent approved by the U.S. Food and Drug Administration (“FDA”) on March 6, 2026, to obtain FDA approval for each PMF to manufacture PYLARIFY TruVu, to obtain adequate coding, coverage and payment, including transitional pass-through payment status, for PYLARIFY TruVu and to have customers adopt PYLARIFY TruVu; (iii) the availability of raw materials, key components, equipment, manufacturing time slots, either used in the production of our products and product candidates, or by customers of our products and product candidates, including, but not limited to PET scanners for PYLARIFY, PYLARIFY TruVu, Neuraceq, MK-6240, LNTH-2501 and NAV-4694; (iv) our ability to have third parties manufacture our products and product candidates and our ability to manufacture DEFINITY in our in-house manufacturing facility, in amounts and at the times needed; (v) our ability to satisfy our obligations under our existing clinical development partnerships using Neuraceq, MK-6240 or NAV-4694 and other assets as a research tool and under the license agreements through which we have rights to those assets, and to further develop and commercialize MK-6240 and NAV-4694 as approved products; (vi) our ability to continue to successfully integrate acquisitions, including of Lantheus Biosciences Ltd. (formerly Life Molecular Imaging Limited) and Evergreen Theragnostics, Inc., which could be impacted by unforeseen expenses related to integration activities, the potential for unforeseen liabilities within those businesses, the ability to integrate disparate information technology systems, retain key talent and create a merged corporate culture that successfully realizes the full potential of the combined organization; (vii) our ability to obtain FDA approval for LNTH-2501, our investigational kit for the preparation of Gallium-68 edotreotide injection, which has been studied for use in conjunction with a PET scan to stage and localize neuroendocrine tumors in adult and pediatric patients and to successfully commercialize LNTH-2501 if approved; (viii) our ability to obtain final FDA approval for PNT2003, which received FDA tentative approval in March 2026, to be successful in the patent litigation associated with PNT2003 and to successfully commercialize PNT2003 if approved; (ix) the cost, efforts and timing for clinical development, manufacturing, regulatory approval, adequate coding, coverage and payment and successful commercialization of our newly approved products, product candidates and new clinical applications and territories for our products, in each case, that we or our strategic partners may undertake, including those investigational assets for which FDA approval has been obtained or is anticipated to be obtained this year; (x) our ability to identify opportunities to collaborate with strategic partners and to acquire or in-license additional diagnostic and therapeutic product opportunities in oncology, neurology and other strategic areas and continue to grow and advance our pipeline of products; (xi) the effect that changes to management, including the recent turnover in our leadership and senior management team, could have on our business; and (xii) the risk and uncertainties discussed in our filings with the Securities and Exchange Commission (including those described in the Risk Factors section in our Annual Reports on Form 10-K and our Quarterly Reports on Form 10-Q).

- Tables Follow -

Page 4 of 11


 

Lantheus Holdings, Inc.

Consolidated Statements of Operations

(in thousands, except per share data – unaudited)

 

 

Three Months Ended
March 31,

 

 

 

2026

 

 

2025

 

Revenues

 

$

377,333

 

 

$

372,764

 

Cost of goods sold

 

 

146,411

 

 

 

135,064

 

Gross profit

 

 

230,922

 

 

 

237,700

 

Operating expenses

 

 

 

 

 

 

Sales and marketing

 

 

52,684

 

 

 

42,503

 

General and administrative

 

 

57,533

 

 

 

56,816

 

Research and development

 

 

39,379

 

 

 

36,314

 

Total operating expenses

 

 

149,596

 

 

 

135,633

 

Operating income

 

 

81,326

 

 

 

102,067

 

Interest expense

 

 

4,864

 

 

 

4,804

 

Investment in equity securities - unrealized (gain) loss

 

 

(14,905

)

 

 

14,862

 

Gain on sale of business, net of transaction costs

 

 

(59,328

)

 

 

 

Other income, net

 

 

(5,710

)

 

 

(14,128

)

Income before income taxes

 

 

156,405

 

 

 

96,529

 

Income tax expense

 

 

37,988

 

 

 

23,584

 

Net income

 

$

118,417

 

 

$

72,945

 

Net income per common share:

 

 

 

 

 

 

Basic

 

$

1.83

 

 

$

1.06

 

Diluted

 

$

1.80

 

 

$

1.02

 

Weighted average common shares outstanding:

 

 

 

 

 

 

Basic

 

 

64,736

 

 

 

68,675

 

Diluted

 

 

65,772

 

 

 

71,461

 

 

 

 

 

 

 

 

 

Page 5 of 11


 

Lantheus Holdings, Inc.

Consolidated Revenues Analysis

(in thousands, except percent data – unaudited)

 

 

Three Months Ended

 

 

 

March 31,

 

 

 

2026

 

 

2025

 

 

Change $

 

 

Change %

 

PYLARIFY

 

$

240,924

 

 

$

257,654

 

 

$

(16,730

)

 

 

(6.5

)%

Total oncology

 

 

240,924

 

 

 

257,654

 

 

 

(16,730

)

 

 

(6.5

)%

Neuraceq

 

 

35,439

 

 

 

 

 

 

35,439

 

 

 

100.0

%

Total neurology

 

 

35,439

 

 

 

 

 

 

35,439

 

 

 

100.0

%

DEFINITY

 

 

84,627

 

 

 

79,211

 

 

 

5,416

 

 

 

6.8

%

Total cardiology

 

 

84,627

 

 

 

79,211

 

 

 

5,416

 

 

 

6.8

%

Strategic partnerships and other

 

 

16,343

 

 

 

10,747

 

 

 

5,596

 

 

 

52.1

%

SPECT

 

 

 

 

 

25,152

 

 

 

(25,152

)

 

 

(100.0

)%

Total revenues

 

$

377,333

 

 

$

372,764

 

 

$

4,569

 

 

 

1.2

%

 

Page 6 of 11


 

Lantheus Holdings, Inc.

Reconciliation of GAAP to Non-GAAP Financial Measures

(in thousands, except per share and percent data – unaudited)

 

 

Three Months Ended
March 31,

 

 

 

2026

 

 

2025

 

Net income

 

$

118,417

 

 

$

72,945

 

Stock and incentive plan compensation

 

 

16,041

 

 

 

21,198

 

Amortization of acquired intangible assets

 

 

16,723

 

 

 

8,016

 

Campus consolidation costs

 

 

12

 

 

 

60

 

Contingent consideration fair value adjustments

 

 

(358

)

 

 

 

Non-recurring fees

 

 

7,411

 

 

 

2,478

 

Gain on sale of business, net of transaction costs

 

 

(59,328

)

 

 

 

Strategic collaboration and license costs

 

 

(131

)

 

 

5,413

 

Investment in equity securities - unrealized (gain) loss

 

 

(14,905

)

 

 

14,862

 

Acquisition, integration and divestiture-related items

 

 

6,365

 

 

 

4,751

 

Other

 

 

80

 

 

 

(4,452

)

Income tax effect of non-GAAP adjustments(a)

 

 

5,474

 

 

 

(15,796

)

Adjusted net income

 

$

95,801

 

 

$

109,475

 

Adjusted net income, as a percentage of revenues

 

 

25.4

%

 

 

29.4

%

 

 

 

 

 

 

 

 

 

 

Three Months Ended
March 31,

 

 

 

2026

 

 

2025

 

Net income per share - diluted

 

$

1.80

 

 

$

1.02

 

Stock and incentive plan compensation

 

 

0.24

 

 

 

0.30

 

Amortization of acquired intangible assets

 

 

0.25

 

 

 

0.11

 

Campus consolidation costs

 

 

0.00

 

 

 

0.00

 

Contingent consideration fair value adjustments

 

 

(0.01

)

 

 

 

Non-recurring fees

 

 

0.11

 

 

 

0.03

 

Gain on sale of business, net of transaction costs

 

 

(0.90

)

 

 

 

Strategic collaboration and license costs

 

 

(0.00

)

 

 

0.07

 

Investment in equity securities - unrealized (gain) loss

 

 

(0.23

)

 

 

0.21

 

Acquisition, integration and divestiture-related items

 

 

0.10

 

 

 

0.07

 

Other

 

 

0.00

 

 

 

(0.06

)

Income tax effect of non-GAAP adjustments(a)

 

 

0.08

 

 

 

(0.22

)

Adjusted net income per share - diluted(b)

 

$

1.46

 

 

$

1.53

 

Weighted-average common shares outstanding - diluted

 

 

65,772

 

 

 

71,461

 

 

 

 

 

 

 

 

 

(a)
Represents the estimated income tax effect of the adjustments between GAAP net income and adjusted net income (non-GAAP).
(b)
Amounts may not add due to rounding.

Page 7 of 11


 

Lantheus Holdings, Inc.

Reconciliation of GAAP to Non-GAAP Financial Measures (Continued)

(in thousands, except per share and percent data – unaudited)

 

 

Three Months Ended
March 31,

 

 

 

2026

 

 

2025

 

Operating income

 

$

81,326

 

 

$

102,067

 

Stock and incentive plan compensation

 

 

16,041

 

 

 

21,198

 

Amortization of acquired intangible assets

 

 

16,723

 

 

 

8,016

 

Campus consolidation costs

 

 

12

 

 

 

60

 

Contingent consideration fair value adjustments

 

 

(358

)

 

 

 

Non-recurring fees

 

 

7,411

 

 

 

2,478

 

Strategic collaboration and license costs

 

 

(131

)

 

 

5,413

 

Acquisition, integration and divestiture-related items

 

 

8,044

 

 

 

4,751

 

Other

 

 

80

 

 

 

275

 

Adjusted operating income

 

$

129,148

 

 

$

144,258

 

Adjusted operating income, as a percentage of revenues

 

 

34.2

%

 

 

38.7

%

 

 

 

 

 

 

 

 

Page 8 of 11


 

Lantheus Holdings, Inc.

Reconciliation of Free Cash Flow

(in thousands – unaudited)

 

 

Three Months Ended
March 31,

 

 

 

2026

 

 

2025

 

Net cash provided by operating activities

 

$

125,127

 

 

$

107,563

 

Capital expenditures

 

 

(3,226

)

 

 

(8,718

)

Free cash flow

 

$

121,901

 

 

$

98,845

 

 

 

 

 

 

 

 

Net cash provided by (used in) investing activities

 

$

25,986

 

 

$

(63,718

)

Net cash used in financing activities

 

$

(11,623

)

 

$

(18,219

)

 

 

 

 

 

 

 

 

Page 9 of 11


 

Lantheus Holdings, Inc.

Condensed Consolidated Balance Sheets

(in thousands – unaudited)

 

 

March 31,

 

 

December 31,

 

 

 

2026

 

 

2025

 

Assets

 

 

 

 

 

 

Current assets:

 

 

 

 

 

 

Cash and cash equivalents

 

$

498,582

 

 

$

359,121

 

Accounts receivable, net

 

 

355,666

 

 

 

358,640

 

Inventory, net

 

 

61,339

 

 

 

64,674

 

Income tax receivable

 

 

1,487

 

 

 

15,387

 

Other current assets

 

 

25,214

 

 

 

21,400

 

Assets held for sale

 

 

 

 

 

80,742

 

Total current assets

 

 

942,288

 

 

 

899,964

 

Investment in equity securities

 

 

58,312

 

 

 

42,213

 

Long-term notes receivable

 

 

92,103

 

 

 

 

Property, plant and equipment, net

 

 

157,563

 

 

 

163,686

 

Intangibles, net

 

 

706,058

 

 

 

722,779

 

Goodwill

 

 

239,399

 

 

 

239,517

 

Deferred tax assets, net

 

 

89,122

 

 

 

109,196

 

Other long-term assets

 

 

61,742

 

 

 

50,044

 

Total assets

 

$

2,346,587

 

 

$

2,227,399

 

Liabilities and Stockholders’ Equity

 

 

 

 

 

 

Current liabilities:

 

 

 

 

 

 

Current portion of long-term debt and other borrowings

 

$

803

 

 

$

738

 

Accounts payable

 

 

45,875

 

 

 

42,906

 

Accrued expenses and other current liabilities

 

 

286,488

 

 

 

267,307

 

Liabilities held for sale

 

 

 

 

 

22,468

 

Total current liabilities

 

 

333,166

 

 

 

333,419

 

Asset retirement obligations

 

 

139

 

 

 

138

 

Long-term debt and other borrowings, net of current portion

 

 

569,604

 

 

 

568,678

 

Long-term deferred tax liabilities

 

 

53,508

 

 

 

54,246

 

Long-term contingent consideration liabilities, net of current portion

 

 

72,647

 

 

 

73,255

 

Other long-term liabilities

 

 

105,235

 

 

 

107,866

 

Total liabilities

 

 

1,134,299

 

 

 

1,137,602

 

Total stockholders’ equity

 

 

1,212,288

 

 

 

1,089,797

 

Total liabilities and stockholders’ equity

 

$

2,346,587

 

 

$

2,227,399

 

 

 

 

 

 

 

 

 

Page 10 of 11


 

###

Contacts:

Mark Kinarney

Vice President, Investor Relations

978-671-8842

ir@lantheus.com

 

Melissa Downs

Executive Director, External Communications

646-975-2533

media@lantheus.com

Page 11 of 11


FAQ

How did Lantheus (LNTH) perform financially in Q1 2026?

Lantheus reported Q1 2026 revenue of $377.3 million, up 1.2% year over year, with GAAP diluted EPS rising to $1.80 from $1.02. Adjusted diluted EPS was $1.46, slightly below $1.53 a year earlier, reflecting lower underlying operating profit.

What drove Lantheus (LNTH) earnings growth in Q1 2026?

GAAP net income increased to $118.4 million, largely supported by a $59.3 million gain on the sale of the SPECT business. Core results were softer, with operating income down 20.3% and adjusted net income down 12.5% compared with Q1 2025.

How did key Lantheus (LNTH) products perform in Q1 2026?

PYLARIFY sales were $240.9 million, down 6.5% year over year. DEFINITY cardiology sales rose 6.8% to $84.6 million, while Neuraceq neurology revenue reached $35.4 million. Total worldwide revenue increased modestly by 1.2% overall.

What recent FDA decisions affect Lantheus (LNTH) products?

The FDA approved PYLARIFY (piflufolastat F18), a new PYLARIFY formulation, with phased launch planned from Q4 2026. The FDA also granted tentative approval for PNT2003 and extended the LNTH‑2501 PDUFA date to June 29, 2026 for manufacturing review.

What guidance did Lantheus (LNTH) provide for full-year 2026?

Lantheus reaffirmed full-year 2026 guidance for revenue of $1.4 billion to $1.45 billion and adjusted fully diluted EPS of $5.00 to $5.25. Management does not provide GAAP EPS guidance due to uncertainty around items like transaction-related expenses.

How strong is Lantheus (LNTH) cash and balance sheet position after Q1 2026?

At March 31, 2026, Lantheus held $498.6 million in cash and cash equivalents, up from $359.1 million at year-end 2025, and generated Q1 free cash flow of $121.9 million. The company also has access to up to $750 million under a revolving credit facility.

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