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Lyra Therapeutics, Inc. SEC Filings

LYRA NASDAQ

Welcome to our dedicated page for Lyra Therapeutics SEC filings (Ticker: LYRA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Tracking a clinical-stage biotech can feel as complex as its science. Lyra Therapeutics’ SEC disclosures weave together XTREO platform chemistry, clinical trial milestones, and funding needs—information scattered across 200-page 10-K reports and surprise 8-K material event notices. Locating the right data points before the market reacts is a genuine challenge.

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Rhea-AI Summary

Lyra Therapeutics (NASDAQ:LYRA) filed an 8-K on June 26, 2025 disclosing a registered direct offering and concurrent private placement.

The company sold 273,012 common shares, 150,360 pre-funded warrants (exercise $0.001) and 846,744 private warrants (exercise $11.56) at a combined price of $11.81, generating about $4.3 million in net proceeds.

  • H.C. Wainwright earns a 7 % placement fee plus 6.5 % on any future warrant cash exercise.
  • Private warrants are immediately exercisable, expire 24 months after the resale registration statement is declared effective and include Black-Scholes cash-out rights upon a fundamental transaction.
  • Beneficial-ownership caps: 9.99 % for pre-funded warrants, 4.99 % (optionally 9.99 %) for private warrants.
  • Proceeds will fund working capital and further clinical, manufacturing and pre-commercial activities for LYR-210.

No additional material events were reported.

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Rhea-AI Summary

Lyra Therapeutics has announced a combined offering of 273,012 shares of common stock and pre-funded warrants to purchase 150,360 shares. The offering includes:

  • Common stock priced at $11.81 per share with two accompanying private warrants
  • Pre-funded warrants at $11.809 per underlying share with $0.001 exercise price
  • Private warrants to purchase up to 846,744 shares at $11.56 exercise price

The total offering is expected to raise approximately $5 million before expenses, with $350,001 in placement agent fees. H.C. Wainwright & Co. is acting as exclusive placement agent. The company recently announced positive Phase 3 ENLIGHTEN 2 trial results for LYR-210 in chronic rhinosinusitis patients, meeting its primary endpoint with statistically significant improvement in cardinal symptoms at week 24.

The offering is subject to Form S-3 limitations, with aggregate market value of common stock held by non-affiliates at $29.2 million. Post-offering shares outstanding will be approximately 1.74 million, assuming full exercise of pre-funded warrants.

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Rhea-AI Summary

Lyra Therapeutics has successfully regained compliance with Nasdaq's minimum bid price requirement (Listing Rule 5550(a)(2)). The company received written confirmation from Nasdaq on June 13, 2025 that its common stock maintained a bid price above $1.00 for 12 consecutive business days from May 28, 2025 to June 12, 2025.

Key details:

  • Trading Symbol: LYRA on Nasdaq Capital Market
  • Stock Type: Common Stock ($0.001 par value per share)
  • Company Status: Emerging growth company
  • Compliance Issue: Now resolved and closed

This development removes a significant regulatory concern for the company and ensures continued listing on the Nasdaq Capital Market. The filing was signed by CFO Jason Cavalier on June 23, 2025.

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FAQ

What is the current stock price of Lyra Therapeutics (LYRA)?

The current stock price of Lyra Therapeutics (LYRA) is $9.11 as of June 28, 2025.

What is the market cap of Lyra Therapeutics (LYRA)?

The market cap of Lyra Therapeutics (LYRA) is approximately 13.8M.

What is the primary focus of Lyra Therapeutics, Inc.?

Lyra Therapeutics specializes in developing integrated drug and delivery solutions for chronic ear, nose, and throat disorders, with a particular focus on chronic rhinosinusitis (CRS). Their approach emphasizes sustained, localized treatment using bioresorbable implants.

How does the XTREO technology platform work?

The XTREO platform integrates drug formulation with a targeted delivery system to administer medications directly to affected sinonasal tissues. This technology ensures prolonged anti-inflammatory effects through controlled drug release, eliminating the need for repeated administrations.

What makes Lyra Therapeutics' product candidates unique?

The company's product candidates are designed as bioresorbable polymeric matrices that deliver continuous therapy over months. This unique design allows for non-invasive, in-office administration, providing a sustained therapeutic effect while reducing treatment frequency.

In which market segments does the company operate?

Lyra Therapeutics operates within the biotechnology and medical device sectors, with a specialized focus on ENT therapeutics. Their niche is the development of localized treatments for conditions like chronic rhinosinusitis.

How does Lyra Therapeutics differentiate itself from competitors?

Unlike traditional therapies, Lyra Therapeutics emphasizes a fully integrated approach that marries drug development with advanced delivery technology. Their focus on sustained, localized treatment for CRS sets them apart in addressing the unmet needs of patients with chronic ENT disorders.

What are the key components of the company’s clinical development program?

The clinical development program is built on rigorous research and multiple clinical studies designed to validate the safety and efficacy of its integrated treatment solutions. These studies evaluate both immediate and long-term outcomes in patients with chronic rhinosinusitis, underpinning the scientific and practical value of their therapy.

How is the company addressing patient needs in chronic rhinosinusitis?

By developing long-acting, anti-inflammatory implants that can deliver continuous therapy, Lyra Therapeutics aims to significantly improve symptom management for CRS patients. Their emphasis on non-invasive, sustained treatment provides an attractive alternative for those who have experienced limited relief from standard therapies.
Lyra Therapeutics, Inc.

NASDAQ:LYRA

LYRA Rankings

LYRA Stock Data

13.85M
1.06M
0.6%
50.86%
2.87%
Biotechnology
Surgical & Medical Instruments & Apparatus
Link
United States
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