Veradermics (NYSE: MANE) posts strong VDPHL01 Phase 2 female data
Filing Impact
Filing Sentiment
Form Type
8-K
Rhea-AI Filing Summary
Veradermics, Incorporated reported positive topline Phase 2 data from Study ‘207’ of VDPHL01, an extended-release oral minoxidil tablet, in women with mild-to-moderate pattern hair loss. Female participants receiving 4.5 mg once or twice daily for 6 months showed objective hair growth and high patient-reported benefit.
Average non-vellus Target Area Hair Count increased 22.7 hairs/cm² in the once-daily arm and 23.3 hairs/cm² in the twice-daily arm at Month 6. On the Androgenetic Alopecia Impact Rating Scale, 88.9% (once-daily) and 90.0% (twice-daily) of women reported ‘improved’ or ‘much improved’ hair coverage, while investigators graded 100% and 90% of participants, respectively, as improved. Improvement was already seen at Month 2, with investigators and patients reporting benefits in 67.2% and 63.2% of participants.
VDPHL01 was generally well tolerated through Month 6, with no treatment-related serious adverse events and no cardiac adverse events of special interest; the most common adverse events were hypertrichosis and peripheral edema. Veradermics is running registration-directed Phase 2/3 trials in male and female pattern hair loss, with key topline readouts expected in 2026–2027.
Positive
- Phase 2 Study ‘207’ of VDPHL01 in female pattern hair loss showed mean non-vellus hair count gains of 22.7 and 23.3 hairs/cm² and patient-reported improvement rates near 90%, supporting the ongoing registration-directed Phase 2/3 program.
Negative
- None.
Insights
Analyzing...
8-K Event Classification
3 items: 7.01, 8.01, 9.01
3 items
Item 7.01
Regulation FD Disclosure
Disclosure
Material non-public information disclosed under Regulation Fair Disclosure, often investor presentations or guidance.
Item 8.01
Other Events
Other
Voluntary disclosure of events the company deems important to shareholders but not covered by other items.
Item 9.01
Financial Statements and Exhibits
Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Key Figures
Non-vellus hair count gain (once-daily): 22.7 hairs/cm²
Non-vellus hair count gain (twice-daily): 23.3 hairs/cm²
Patient improvement rate (once-daily): 88.9%
+5 more
8 metrics
Non-vellus hair count gain (once-daily)
22.7 hairs/cm²
Average increase at Month 6 in female once-daily VDPHL01 arm of Study ‘207’
Non-vellus hair count gain (twice-daily)
23.3 hairs/cm²
Average increase at Month 6 in female twice-daily VDPHL01 arm of Study ‘207’
Patient improvement rate (once-daily)
88.9%
Women reporting ‘improved’ or ‘much improved’ hair coverage on AAIRS at Month 6
Patient improvement rate (twice-daily)
90.0%
Women reporting ‘improved’ or ‘much improved’ hair coverage on AAIRS at Month 6
Early patient improvement
63.2%
Participants reporting improved hair coverage at Month 2 in Study ‘207’
U.S. women with pattern hair loss
30 million
Estimated U.S. female pattern hair loss population cited by Veradermics
Pattern hair loss market size
$30 billion by 2028
Projected global aesthetics market for pattern hair loss treatments
Earliest VDPHL01 patent expiry
2043
Earliest expiring patent term in the VDPHL01 patent estate
Key Terms
Target Area Hair Count (TAHC), Androgenetic Alopecia Impact Rating Scale (AAIRS), extended-release minoxidil, treatment-emergent adverse events (TEAE), +1 more
5 terms
Target Area Hair Count (TAHC) medical
"VDPHL01 achieved consistent hair growth on the endpoint of non-vellus TAHC"
Androgenetic Alopecia Impact Rating Scale (AAIRS) medical
"patient reported outcome benefit of ‘improved’ or ‘much improved’ on the Androgenetic Alopecia Impact Rating Scale"
Aairs is a standardized rating scale that measures how androgenetic alopecia (pattern hair loss) affects a person’s daily life, self-image, and emotional well‑being. Like a customer satisfaction score for hair health, it helps clinicians and drug developers quantify patient experience, set trial goals, and show investors whether a treatment meaningfully improves quality of life—information that can shape regulatory decisions and market potential.
extended-release minoxidil medical
"VDPHL01, a novel orally-administered extended-release minoxidil formulation, achieved fast onset of hair growth"
treatment-emergent adverse events (TEAE) medical
"Any Treatment Emergent Adverse Events (TEAE) 15 (53.6)"
adverse events of special interest (AESI) medical
"no adverse events of special interest (AESIs) of cardiac origin were observed"
FAQ
What did Veradermics (MANE) announce about Study ‘207’ of VDPHL01?
Veradermics reported positive topline Phase 2 data from Study ‘207’ of VDPHL01, its extended-release oral minoxidil tablet, in women with mild-to-moderate pattern hair loss. Six months of 4.5 mg once- or twice-daily dosing produced measurable hair growth and strong patient-reported improvement.
How effective was VDPHL01 in Veradermics (MANE) Study ‘207’ for female pattern hair loss?
In Study ‘207’, women on VDPHL01 4.5 mg once or twice daily had mean non-vellus hair count gains of 22.7 and 23.3 hairs/cm² at Month 6. On the AAIRS scale, 88.9% and 90.0% reported ‘improved’ or ‘much improved’ hair coverage.
What safety profile did Veradermics (MANE) report for VDPHL01 in Study ‘207’?
VDPHL01 was described as generally well tolerated through Month 6, with no treatment-related serious adverse events and no cardiac adverse events of special interest. In females, 53.6% experienced any treatment-emergent adverse event; hypertrichosis occurred in 21.4% and peripheral edema in 7.1% of participants.
What early treatment effects were seen with VDPHL01 in Veradermics (MANE) Study ‘207’?
Improvement was observed as early as Month 2, the first assessment time point. Investigators graded 67.2% of participants as demonstrating improvement, and 63.2% of women themselves reported improved hair coverage, indicating a relatively fast onset of perceived benefit.
What future clinical milestones did Veradermics (MANE) highlight for VDPHL01?
Veradermics is running a registration-directed Phase 2/3 male trial (Study ‘304’) with topline data anticipated in the second half of 2026. A Phase 2/3 female trial (Study ‘306’) is actively recruiting, with topline results expected in the first half of 2027.
How large is the pattern hair loss market Veradermics (MANE) is targeting with VDPHL01?
The company cites about 80 million people in the U.S. with pattern hair loss, including 30 million women. It references estimates that the global aesthetics market for pattern hair loss treatments could reach approximately $30 billion by 2028.
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): July 15, 2026
(Exact name of registrant as specified in its charter)
(State or other jurisdiction of incorporation) | (Commission File Number) | (IRS Employer Identification No.) | ||||||||||||
| (Address of principal executive offices) | (Zip Code) | |||||||
(Registrant’s telephone number, including area code): (228 ) 372-3376
Not Applicable
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):
| Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) | |||||
| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) | |||||
| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) | |||||
| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) | |||||
Securities registered pursuant to Section 12(b) of the Act:
| Title of each class | Trading Symbol(s) | Name of each exchange on which registered | ||||||||||||
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company x
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
Item 7.01. Regulation FD Disclosure.
On July 15, 2026, Veradermics, Incorporated (the "Company") issued a press release announcing positive topline data from the Phase 2 clinical trial, ‘Study ‘207,’ evaluating VDPHL01 in females with mild-to-moderate pattern hair loss.
A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and the presentation the Company presented on the conference call and webcast is furnished as Exhibit 99.2 to this Current Report on Form 8-K, and both are incorporated by reference herein. The information contained in Item 7.01 of this Current Report on Form 8-K and the Exhibits 99.1 and 99.2 furnished under Item 7.01 of this Current Report on Form 8-K shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall they be deemed incorporated by reference in any filing under the Exchange Act or the Securities Act, regardless of any general incorporation language in such filing.
Item 8.01 Other Events.
On July 15, 2026, the Company announced positive topline results from Study ‘207’ evaluating VDPHL01, a proprietary extended-release oral minoxidil formulation, in females with mild-to-moderate pattern hair loss. Study '207' is a multicenter Phase 2 open label study in adult 21 male and 28 adult female pattern hair loss patients to obtain proof of concept for the safety and efficacy of twelve months of treatment with VDPHL01 8.5 mg twice daily in male patients and VDPHL01 4.5 mg either once or twice daily in female patients with pattern hair loss.
Among female participants who received either VDPHL01 4.5 mg once daily or VDPHL01 4.5 mg twice daily for 6 months, VDPHL01 demonstrated a potentially differentiated clinical profile defined by rapid onset of activity, consistent response across participants, and increases in hair count while being generally well tolerated with no treatment-related serious adverse events and no adverse events of special interest of cardiac origin. The most common adverse events were hypertrichosis and peripheral edema.
In the study, VDPHL01 achieved consistent hair growth on the endpoint of non-vellus Target Area Hair Count and patient reported outcome benefit of ‘improved’ or ‘much improved’ on the Androgenetic Alopecia Impact Rating Scale ("AAIRS") at Month 6. Participants achieved an average increase in non-vellus hair count of 22.7 hairs/cm² and 23.3 hairs/cm² in once daily and twice daily VDPHL01 treatment arms, respectively. Additionally, 88.9% of participants in the once daily dose arm and 90.0% of participants in the twice daily dose arm achieved ‘improved’ or ‘much improved’ hair coverage on the AAIRS.
The consistency of clinically meaningful hair growth reported by participants was further supported by investigator perception of hair growth, with investigators grading 100% (once daily dosing arm) and 90% (twice daily dosing arm) of female participants as having ‘improved’ or ‘much improved’ hair coverage at Month 6. Fast onset of hair growth was also observed by investigators and patients as early as Month 2, the earliest measured time point measured in the trial, with 67.2% of participants graded by investigators as demonstrating improvement and 63.2% of participants reporting improvement in hair coverage at Month 2.
Forward Looking Statements
This Current Report on Form 8-K contains forward-looking statements, which involve risks, uncertainties and contingencies, many of which are beyond the control of Veradermics, which may cause actual results, performance, or achievements to differ materially from anticipated results, performance, or achievements. All statements other than statements of historical facts contained in this Current Report on Form 8-K are forward-looking statements. In some cases, forward-looking statements can be identified by terms such as “may,” “will,” “should,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or the negative of these terms or other similar expressions, although not all forward-looking statements contain these words. You are cautioned not to place undue reliance on these forward-looking statements, including statements regarding the perceived efficacy of VDPHL01; the clinical profile of VDPHL01, including safety profile; the perceived benefits of VDPHL01; the interpretation and significance of clinical data from
Study ’207’ and other clinical trials; the treatment landscape for pattern hair loss and the timing of reporting additional clinical results. These forward-looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties that could cause actual results to differ materially from those anticipated in the forward-looking statements, including: Veradermics’ limited operating history with no products approved for commercial sale; Veradermics’ incurrence of substantial losses since its inception, anticipation of incurring substantial and increasing losses for the foreseeable future and need for substantial additional financing to achieve its goals; Veradermics’ anticipation that its success will depend on the approval and successful commercialization of VDPHL01, which is its lead product candidate, and if Veradermics is unable to obtain regulatory approval for, and successfully commercialize, VDPHL01, or any other current or future product candidates, or experience significant delays in doing so, its business will be materially harmed; the risk that adverse events or undesirable side effects are caused by Veradermics’ product candidates; competition from other companies; and other risks and uncertainties identified in the “Risk Factors” section of Veradermics’ Annual Report on Form 10-K, for the period ended December 31, 2025, and subsequent filings with the U.S. Securities and Exchange Commission. The events and circumstances reflected in the forward-looking statements may not be achieved or occur and actual future results, levels of activity, performance and events and circumstances could differ materially from those projected in the forward-looking statements. Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some of which are beyond Veradermics’ control, these forward-looking statements should not be relied upon as guarantees of future events. Moreover, Veradermics operates in an evolving environment. New risks and uncertainties may emerge from time to time, and management cannot predict all risks and uncertainties. These forward-looking statements speak only as of the date of this Current Report on Form 8-K, and Veradermics undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by applicable law.
Item 9.01 Financial Statements and Exhibits.
(d) Exhibits
| Exhibit No. | Description | |||||||
| 99.1 | Press release issued by the Company on July 15, 2026 | |||||||
| 99.2 | Investor presentation dated July 15, 2026 | |||||||
| 104 | Cover Page Interactive Data File (embedded within the Inline XBRL document) | |||||||
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
| VERADERMICS, INCORPORATED | ||||||||
| By: | /s/ Reid Waldman, M.D. | |||||||
Name: Reid Waldman, M.D. | ||||||||
Title: Chief Executive Officer | ||||||||
Date: July 15, 2026
Exhibit 99.1
Veradermics’ Oral VDPHL01 Delivers Positive Study ‘207’ Phase 2 Clinical Trial Results in Female Pattern Hair Loss Ahead of Upcoming Phase 2/3 Study ‘306’ Readout
VDPHL01, a novel orally-administered extended-release minoxidil formulation, achieved fast onset of hair growth with the majority of study participants reporting improvement in hair coverage as early as Month 2 and consistent treatment effect with approximately 88.9% (once daily) and 90.0% (twice-daily dosing) of patients reporting ‘improved’ or ‘much improved’ outcomes at Month 6
Robust hair growth was observed with a mean increase in non-vellus target area hair count (TAHC) of 22.7 hairs/cm² and 23.3 hairs/cm² at Month 6, in once and twice daily dosing regimens, respectively
VDPHL01 demonstrated a favorable safety and tolerability profile in females that was generally consistent with prior VDPHL01 trials with no treatment-related SAEs and no AESIs of cardiac origin observed
Veradermics anticipates topline results of ‘Study 306’, a Phase 2/3 clinical trial evaluating VDPHL01 in female pattern hair loss, in 1H 2027
Conference call and webcast scheduled for 8:00 a.m. ET today
NEW HAVEN, Conn., July 15, 2026 -- Veradermics, Incorporated (NYSE: MANE), a dermatologist-founded, late-stage biopharmaceutical company focused on developing innovative therapeutics for pattern hair loss, today announced positive topline results from its open-label Phase 2 clinical trial (Study ‘207’) evaluating VDPHL01, a proprietary extended-release oral minoxidil formulation, in females with mild-to-moderate pattern hair loss. VDPHL01 has the potential to become the first FDA-approved oral treatment for female pattern hair loss.
Among female participants who received either VDPHL01 4.5mg once daily or VDPHL01 4.5mg twice daily for 6 months, VDPHL01 demonstrated a potentially differentiated clinical profile defined by rapid onset of activity, consistent response across participants, and increases in hair count while being generally well tolerated with no treatment-related serious adverse events (SAEs) and no adverse events of special interest (AESIs) of cardiac origin.
In the study, VDPHL01 achieved consistent hair growth on the endpoint of non-vellus TAHC and patient reported outcome (PRO) benefits of ‘improved’ or ‘much improved’ on the
Androgenetic Alopecia Impact Rating Scale (AAIRS) at Month 6. Participants achieved an average increase in non-vellus hair count of 22.7 hairs/cm² and 23.3 hairs/ cm² in once daily and twice daily VDPHL01 treatment arms, respectively. Additionally, 88.9% of participants in the once daily dose arm and 90.0% of participants in the twice daily dose arm achieved ‘improved’ or ‘much improved’ hair coverage on the AAIRS.
“Female pattern hair loss has long been underserved with no FDA approved oral prescription treatment options and limited clinical research. As a result, females have disproportionately resorted to using topical over-the-counter options and unproven supplements that do not reliably help them reach their treatment goals,” said Dr. Jerry Shapiro, an internationally recognized board-certified dermatologist, Director of the Hair Clinic and Professor of Dermatology at NYU Langone Medical School who is a paid consultant of Veradermics. “Based on the results of the ‘207’ trial, VDPHL01 is positioned to transform how we treat female pattern hair loss as it moves towards potentially becoming the first and only FDA approved oral treatment for females.”
The consistency of clinically meaningful hair growth reported by participants was further supported by investigator perception of hair growth, with investigators grading 100% (once daily dosing arm) and 90% (twice daily dosing arm) of female participants as having improvement in hair coverage at Month 6. Fast onset of hair growth was also observed by investigators and patients as early as Month 2, the earliest measured time point measured in the trial, with 67.2% of participants graded by investigators as demonstrating improvement and 63.2% of participants reporting improvement in hair coverage at Month 2.
Treatment with VDPHL01 was generally well tolerated through Month 6 with an overall safety profile consistent with prior studies with VDPHL01. No treatment-related SAEs and no AESIs of cardiac origin were observed in this study.
“We are highly encouraged by the positive results from Study ‘207’ evaluating our proprietary extended-release formulation of VDPHL01 in women with pattern hair loss,” said Reid Waldman, M.D., Chief Executive Officer of Veradermics. “Importantly, Study ‘207’ demonstrated strong proof-of-concept on the same endpoints being evaluated in our registration-directed Phase 2/3 Study ‘306’, further strengthening our conviction in that study ahead of its anticipated 1H 2027 readout. Taken together, these data reinforce our belief that VDPHL01, if approved, has the potential to become a differentiated oral treatment option for women with female pattern hair loss and to address the needs of an estimated 30 million women, representing a substantial additive commercial opportunity.”
VDPHL01 is currently being evaluated in an extensive pivotal development program designed to support the approval of VDPHL01 in both female and male pattern hair loss. Veradermics is actively recruiting female participants for its female pattern hair loss Phase 2/3 trial, Study ‘306’, with topline data anticipated in 1H 2027. In April, Veradermics announced topline results from
Study ‘302’, a registration-directed Phase 2/3 trial in male pattern hair loss and, in February, Veradermics announced enrollment completion in its second Phase 3 male trial, Study ‘304’, with topline results anticipated in the second half of 2026.
Veradermics will host a conference call and live webcast today at 8:00 a.m. ET to discuss the Study ‘207’ results. A live webcast will be available on the Events page in the Investors section of the company’s website. A replay will be available following the call.
About VDPHL01
VDPHL01 (extended-release minoxidil tablet) is a proprietary investigational, oral non-hormonal drug in Phase 3 development for pattern hair loss in both women and men. VDPHL01 leverages extended-release technology to deliver a minoxidil product with the potential for improved efficacy and safety. The proprietary extended-release formulation utilizes a gel matrix designed to deliver long-lasting, steady release of minoxidil for sustained absorption. VDPHL01 has been shown to avoid the high peak concentrations of immediate-release oral minoxidil, while extending time above the minimum hair growth threshold to increase time for hair to grow. If approved, VDPHL01 would be the only FDA-approved oral non-hormonal treatment for pattern hair loss in both male and female patients. VDPHL01 is protected by a broad library of patents and patent applications related to the key innovations of VDPHL01. The earliest expiring patent term is 2043.
About Pattern Hair Loss
Pattern hair loss, also known as androgenetic alopecia, affects an estimated 80 million people in the United States (30 million women and 50 million men). Pattern hair loss can have a significant impact on quality of life, affecting an individual’s mental health and relationships. People with pattern hair loss often experience depression, low self-esteem, and social withdrawal. There have been no new FDA-approved prescription medicines for pattern hair loss in nearly 30 years. In addition, current treatments include over the counter “nutraceuticals” that produce inconsistent results and contribute to high dissatisfaction among participants and healthcare providers. The prevalence of pattern hair loss and the market demand for new treatments contribute to making it the largest aesthetics market worldwide, projected to reach approximately $30 billion by 2028.
About Study ‘207’
Study ‘207’ is a multicenter Phase 2 open label study in 21 adult male and 28 adult female pattern hair loss patients to obtain proof of concept for the safety and efficacy of twelve months of treatment with VDPHL01 8.5 mg twice daily in male patients and VDPHL01 4.5 mg either once or twice daily in female patients with pattern hair loss.
About Veradermics, Inc.
Veradermics is a dermatologist-founded, late clinical-stage biopharmaceutical company focused on developing innovative therapeutics for pattern hair loss. Veradermics aims to develop a
focused portfolio of aesthetic dermatology product candidates targeting high-prevalence dermatologic conditions, with potential selective development of medical dermatology product candidates. Its lead program, VDPHL01, is being developed as an oral, non-hormonal treatment for men and women with pattern hair loss, to reduce the barriers to wide adoption of chronic hair loss therapy and potentially transform pattern hair loss treatment. VDPHL01 is an oral, extended-release proprietary formulation of minoxidil, a proven hair growth agent, designed to maximize minoxidil’s impact on hair restoration while minimizing the risk of cardiac activity. For additional information, visit www.veradermics.com and follow us on LinkedIn and Instagram.
Forward-Looking Statements
This press release contains forward-looking statements, which involve risks, uncertainties and contingencies, many of which are beyond the control of Veradermics, which may cause actual results, performance, or achievements to differ materially from anticipated results, performance, or achievements. All statements other than statements of historical facts contained in this press release are forward-looking statements. In some cases, forward-looking statements can be identified by terms such as “may,” “will,” “should,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or the negative of these terms or other similar expressions, although not all forward-looking statements contain these words. Investors are cautioned not to place undue reliance on these forward-looking statements, including statements regarding the perceived efficacy of VDPHL01; the clinical profile of VDPHL01, including its safety profile; the perceived benefits of VDPHL01; the interpretation and significance of clinical data from Study ’207’ and other clinical trials; VDPHL01’s use as the preferred treatment for pattern hair loss; the treatment landscape for pattern hair loss; the timing of reporting additional clinical results, including anticipated data from Study ‘306’; the enrollment progress in Study ‘306’; VDPHL01’s potential to become the first FDA-approved non-hormonal oral treatment for pattern hair loss; the projected size of the market for pattern hair loss; the potential commercial opportunity for VDPHL01; and the scope and duration of patent protection for VDPHL01. These forward-looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties that could cause actual results to differ materially from those anticipated in the forward-looking statements, including: Veradermics’ limited operating history with no products approved for commercial sale; Veradermics’ incurrence of substantial losses since its inception, anticipation of incurring substantial and increasing losses for the foreseeable future and need for substantial additional financing to achieve its goals; Veradermics’ anticipation that its success will depend on the approval and successful commercialization of VDPHL01, which is its lead product candidate, and if Veradermics is unable to obtain regulatory approval for, and successfully commercialize, VDPHL01, or any other current or future product candidates, or experience significant delays in doing so, its business will be materially harmed; the risk that adverse events or undesirable side effects are caused by Veradermics’ product candidates; competition from other companies; and other risks and uncertainties identified in the “Risk
Factors” section of Veradermics’ Annual Report on Form 10-K, for the period ended December 31, 2025, and subsequent filings with the U.S. Securities and Exchange Commission. The events and circumstances reflected in the forward-looking statements may not be achieved or occur and actual future results, levels of activity, performance and events and circumstances could differ materially from those projected in the forward-looking statements. Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some of which are beyond Veradermics’ control, these forward-looking statements should not be relied upon as guarantees of future events. Moreover, Veradermics operates in an evolving environment. New risks and uncertainties may emerge from time to time, and management cannot predict all risks and uncertainties. These forward-looking statements speak only as of the date of this press release, and Veradermics undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by applicable law.
Contacts
Media:
Catherine Collier Kyroulis
media@veradermics.com
(917) 886-5586
Investors:
investors@veradermics.com
Study ‘207’ Phase 2 Topline Open Label Data in Females with Mild-to-Moderate Pattern Hair Loss July 2026
agenda 2 1 Opening Remarks 2 Study ‘207’ results 3 KOL Discussion 4 VDPHL01 Commercial Opportunity 5 Closing Remarks 6 Q&A Reid Waldman, M.D. Chief Executive Officer, Veradermics Mark Neumann Chief Commercial & Strategy Officer, Veradermics Dominic Carrano Chief Financial Officer, Veradermics Jerry Shapiro, M.D.* NYU Langone Health MANE Speakers Joined by JULY 2026 *Dr. Jerry Shapiro is a paid consultant for Veradermics.
This presentation contains forward-looking statements that involve substantial risks and uncertainties. All statements other than historical factual information are forward-looking statements, including without limitation statements regarding our product development activities for VDPHL01 and ongoing clinical trials; the ability of clinical trials to demonstrate safety and efficacy of VDPHL01; the beneficial characteristics, and the potential safety, efficacy and therapeutic effects of VDPHL01; our ability to pursue and execute our strategy for our indications, business, programs and technology; the timing of and our ability to obtain and maintain regulatory approval of our product candidates; our ability to compete with companies currently selling, marketing or engaged in the development of treatments for diseases that our product candidates are designed to target, including pattern hair loss (PHL); our estimates regarding the size and growth potential of the commercial opportunity for VDPHL01 and our current product candidates or other product candidates we may identify and pursue, and our ability to serve those markets; objectives for future operations and other estimates contained herein. In some cases, you can identify forward-looking statements because they contain words such as “may,” “will,” “shall,” “should,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or the negative of these words or other similar expressions that concern our expectations, strategy, plans or intentions, although not all forward-looking statements are accompanied by such words. Forward-looking statements are based on assumptions and assessments made by our management in light of their experience and perceptions of historical trends, current conditions, expected future developments and other factors they believe to be appropriate, and speak only as of the date of this presentation. Disclaimer 3 Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, performance or other events to be materially different from any future results, performance or other events expressed or implied by the forward-looking statements, including the risks and uncertainties identified in the “Risk Factors” section of our Annual Report on Form 10-K, for the period ended December 31, 2025, and subsequent filings with the U.S. Securities and Exchange Commission. Given these uncertainties, you should not place undue reliance on forward-looking statements. Our actual future results, performance or other events may be materially different from what we expect. Except as required by law, we assume no obligation to update these forward-looking statements, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. Market data and industry information used throughout this presentation are based on management’s knowledge of the industry and the good faith estimates of management. We also relied, to the extent available, upon management’s review of independent industry surveys and publications and other publicly available information prepared by a number of third-party sources. All of the market data and industry information used in this presentation involves a number of assumptions and limitations, and you are cautioned not to give undue weight to such estimates. Although we believe that these sources are reliable as of their respective dates, we cannot guarantee the accuracy or completeness of this information, and we have not independently verified this information. Projections, assumptions and estimates of our future performance and the future performance of the industry in which we operate are necessarily subject to a high degree of uncertainty and risk due to a variety of factors. These and other factors could cause results to differ materially from those expressed in our estimates and beliefs and in the estimates prepared by independent parties. The trademarks included herein are the property of the owners thereof and are used for reference purposes only. Such use should not be construed as an endorsement of such products. This presentation discusses potential future product candidates that are investigational only and have not yet been approved for marketing by the U.S. Food and Drug Administration. No representation is made as to the safety or effectiveness of these potential future product candidates for the use for which such potential future product candidates are being studied. JULY 2026
4 First positive Phase 2 outcome for an oral PHL treatment in females in the U.S. Increases conviction in upcoming Study ‘306’ Phase 2/3 registration- directed female PHL readout (anticipated 1H27) Supports potential for VDPHL01 to address large, 30M patient female pattern hair loss market Positions VDPHL01 to become the first and only FDA approved oral treatment for female PHL Study ‘207’ achieved endpoints supporting upcoming Phase 2/3 readout Positive efficacy signals on both TAHC and PRO High rate of consistency across efficacy endpoints Positive and consistent treatment effect High rate of PRO and IGA response punctuates consistency of response Rapid onset of hair growth 63.2% of participants reported improvement in hair coverage as early as Month 2 Generally well-tolerated Safety profile consistent with prior VDPHL01 trials JULY 2026
50 50 32 30 16 8 30 10 20 30 40 50 60 PHL (Men) Acne (All Ages) Atopic Dermatitis (Eczema) PHL (Women) Rosacea Psoriasis Vitiligo Pattern hair loss impacts ~80 million people in the U.S.1 5 M Men with PHL Pa tie nt s Af fe ct ed in th e U .S .1 ( M ) 1American Academy of Dermatology. (n.d.). Skin conditions by the numbers. https://www.aad.org/media/stats/conditions/hair-loss M Women with PHL JULY 2026 Million U.S. patients: ~50M men without a new oral treatment in ~30 years; ~30M women without FDA-approved oral treatment options~80
Female pattern hair loss patients are impacted by current treatment gap and are seeking better options 6 Actively Seeking Treatment Females are more likely to seek treatment; lack of awareness of Rx options is a primary driver of OTC usage2 Impacted Quality of Life Patient surveys indicate women experience a greater impact on QOL than males with PHL 1 High Unmet Need 30M women in the U.S. with PHL with no oral FDA-approved treatment options High Treatment Cycling 86% of topical minoxidil users discontinue treatment3 JULY 2026 1Hwang HW, Ryou S, Jeong JH, Lee JW, Lee KJ, Lee SB, Shin HT, Byun JW, Shin J, Choi GS. The Quality of Life and Psychosocial Impact on Female Pattern Hair Loss. Ann Dermatol. 2024 Feb;36(1):44-52. doi: 10.5021/ad.23.082. PMID: 38325433; PMCID: PMC10861302. 2ClearView Analysis 2026. 3 https://pmc.ncbi.nlm.nih.gov/articles/PMC10149432/#CR5 – Minoxidil compliance and satisfaction
VDPHL01’s proprietary extended-release technology was designed to optimize efficacy and safety 7 10x difference between minoxidil hair growth threshold and minoxidil cardiac activity threshold VDPHL01 is designed to deliver nearly twice the total amount of minoxidil over 12h and maintains concentrations above the hair growth threshold twice as long vs. a 2.5 mg IR tablet* First and only minoxidil extended-release tablet and only oral minoxidil tablet positioned for potential approval for the treatment of PHL 10x Blunted maximum observed concentration (Cmax) below FDA recognized cardiac activity threshold achieved by extended release is designed to avoid cardiac adverse effects compared to immediate release *As per pharmacokinetics data from average plasma concentrations for male patients (n=10) from Study QSC300720 evaluating males taking VDPHL01 8.5mg and minoxidil 2.5 mg IR 0 5 10 15 20 25 30 Pl as m a C on ce nt ra tio n (n g/ m L) C a r d i a c A c t i v i t y T h r e s h o l d ( 2 0 n g / m L ) H a i r g r o w t h t h r e s h o l d ( 1 . 6 2 n g / m L ) I d e a l M i n o x i d i l P l a s m a T a r g e t C o n c e n t r a t i o n JULY 2026
Minoxidil mechanism of action is capacity-limited and time dependent 8 Minoxidil Hair follicles contain the SULT1A1 sulfotransferase enzyme that locally converts minoxidil to its active metabolite, minoxidil sulfate Hair growth is stimulated at low plasma levels of minoxidil because of its local metabolism to minoxidil sulfate at the hair bulb. 2 VDPHL01 is designed to increase the duration of exposure to metabolized minoxidil sulfate at the hair follicle PARENT DRUG ACTIVE DRUG 1 1 2 Minoxidil Sulfate VDPHL01 is designed to optimize the consistency and duration of exposure to active minoxidil sulfate JULY 2026
Key Efficacy Endpoints*: • Changes from baseline in non-vellus TAHC using digital image analysis at Month 6 • Proportion of participants who achieve treatment benefit, defined as a PRO response of “Improved” or “Much Improved” at Month 6 Study ‘207’ in females: Phase 2 open-label study QD: Daily Dosing BID: 2x/day Dosing * List of other efficacy endpoints is not exhaustive but is representative of co-primary endpoints in registration-directed studies evaluating VDPHL01 in males and females TAHC: Target Area Hair Count PRO: Proprietary patient reported outcomes (PRO) scale designed for the VDPHL01 clinical trials Primary Objective: Obtain proof of concept for safety and efficacy of VDPHL01 administered in male and female participants with PHL Screening Period Open Label Study (24 weeks) n=28 Female Group 1: VDPHL01 4.5 mg BID Female Group 2: VDPHL01 4.5 mg QD Follow-Up Period | 9 JULY 2026
Study ‘207’ clinical trial endpoints 10 Patient-reported outcome (PRO)Target area hair count (TAHC) AAIRS 7-Point Scale 3 = MUCH IMPROVED 2 = IMPROVED 1 = A LITTLE IMPROVED 0 = NO CHANGE -1 = A LITTLE WORSE -2 = WORSE -3 = MUCH WORSE *Efficacy endpoint Baseline Month 2 Screening Month 2 Month 4 Patient tattooed for location replicability TAHC endpoint leverages the only measurement methodology used for FDA approval in PHL since 1997 • Digital analysis lines up consecutive images to ensure the same location is captured. • in diameter are counted as being non-vellus. • Digital analysis algorithm discerns both increases in number and thickness of hairs. • Accuracy of analysis is ensured by utilizing counts from 2 separate technicians. PRO endpoint is evaluated using the Androgenetic Alopecia Impact Rating Score (AAIRS) • All photography is standardized and undergoes quality control to ensure consistent imagery and parting • Patients are shown full-size photographs at baseline and evaluated time points to directly assess changes to the severity of their PHL on a 7-point scale from ‘Much Worsened’ to ‘Much Improved’ JULY 2026
4.3 -1.3 5.3 13.4 6.1 -1.7 9.5 -5 0 5 10 15 20 25 30 35 N on -V el lu s T A H C In cr ea se Hair Count Increase (Placebo/Control*) Hair Count Increase (Active) Existing studies of treatment options for female PHL show modest hair count changes 11 [n=33] Topical minoxidil 5% female data from Bergfeld (2016). Oral finasteride female data is from Price (2000). IR Oral Minoxidil female data is from Ramos (2020). Oral Spironolactone female data is from Werachattawatchai et al. (2025). *Spironolactone + topical minoxidil 3% female data was evaluated against topical minoxidil 3% female control arm, not placebo, and did not demonstrate statistically significant benefit. [n=180*] Oral Finasteride 1mg (Month 12) Spironolactone 100mg + Topical Minoxidil 3%* (Month 6) TAHC Increase in Females absolute; from baseline; represents results from female populations participating in applicable studies JULY 2026 Topical Minoxidil 5% (Month 6) IR Oral Minoxidil 1mg (Month 6) N/A Existing Minoxidil Treatment Options Hormonal Treatment Options
Both female doses in Study ‘207’ showed objective improvements in Target Area Hair Count (TAHC) at Month 6 12 22.7 23.3 0 5 10 15 20 25 30 35 VDPHL01 4.5mg QD VDPHL01 8.5mg BID N on -V el lu s T A H C In cr ea se Non-Vellus TAHC Increase absolute; from baseline at Month 6 VDPHL01 4.5mg QD VDPHL01 4.5mg BID JULY 2026
4.3 -1.3 5.3 22.7 23.3 13.4 6.1 -1.7 9.5 -5 0 5 10 15 20 25 30 35 N on -V el lu s T A H C In cr ea se Hair Count Increase (Placebo/Control*) Hair Count Increase (Active) VDPHL01 has the potential to set a new bar for female pattern hair loss treatments 13 [n=33] VDPHL01 Data are presented from female study arms of Study ‘207’. Topical minoxidil 5% female data from Bergfeld (2016). Oral finasteride female data is from Price (2000). IR Oral Minoxidil female data is from Ramos (2020). Oral Spironolactone female data is from Werachattawatchai et al. (2025). *Spironolactone + topical minoxidil 3% female data was evaluated against topical minoxidil 3% female control arm, not placebo, and did not demonstrate statistically significant benefit. Note: No head-to-head studies comparing VDPHL01 to finasteride or other forms of minoxidil have been conducted. The results of this retrospective post hoc cross-trial comparison may not be directly comparable. Differences exist between trial designs and participant characteristics, and caution should be exercised when comparing data across unrelated studies. [n=180*] VDPHL01 4.5mg QD (Month 6) VDPHL01 4.5mg BID (Month 6) Oral Finasteride 1mg (Month 12) Spironolactone 100mg + Topical Minoxidil 3%* (Month 6) TAHC Increase in Females absolute; from baseline; represents results from female populations participating in applicable studies JULY 2026 Topical Minoxidil 5% (Month 6) IR Oral Minoxidil 1mg (Month 6) N/AN/AN/A
PRO: both female doses in Study ‘207’ demonstrated positive patient reported outcomes 14 88.9% 90.0% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% VDPHL01 8.5mg QD VDPHL01 8.5mg BID % R es po ns e AAIRS 7-Point Scale 3 = MUCH IMPROVED 2 = IMPROVED 1 = A LITTLE IMPROVED 0 = NO CHANGE -1 = A LITTLE WORSE -2 = WORSE -3 = MUCH WORSE *Efficacy endpoint VDP L01 4.5mg QD VDPHL01 4.5mg BID VDPHL01 4.5mg QD & BID PRO +2 at Month 6 JULY 2026
Investigator global assessment underscored consistency of response in female participants 15 100.0% 90.0% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% VDPHL01 8.5mg QD VDPHL01 8.5mg BID % IG A R es po nd er IGA 7-Point Scale 3 = GREATLY INCREASED 2 = MODERATELY INCREASED 1 = SLIGHTLY INCREASED 0 = NO CHANGE -1 = SLIGHTLY DECREASED -2 = MODERATELY DECREASED -3 = GREATLY DECREASED *Captured in IGA endpoint VDPHL01 4.5mg QD & BID % Responders with any observable improvement at Month 6 VDPHL01 4.5mg QD VDPHL01 4.5mg BID JULY 2026
Study ‘207’ Before and After Photos: Savin I-4 Responder 16 Images represent a responder defined by a response of 'Improved' or 'Much Improved' on the AAIRS Patient Reported Outcome, assessed to have Grade I-4 pattern hair loss on the Savin scale. Individual results may vary. Month 6Baseline JULY 2026
Study ‘207’ Before and After Photos: Savin II-1 Responder 17 Images represent a responder defined by a response of 'Improved' or 'Much Improved' on the AAIRS Patient Reported Outcome, assessed to have Grade II-1 pattern hair loss on the Savin scale. Individual results may vary. Month 6Baseline JULY 2026
Study ‘207’ Before and After Photos: Savin II-2 Responder 18 Images represent a responder defined by a response of 'Improved' or 'Much Improved' on the AAIRS Patient Reported Outcome, assessed to have Grade II-2 pattern hair loss on the Savin scale. Individual results may vary. Month 6Baseline JULY 2026
Eyebrow Assessments 19
Eyebrow hypotrichosis can have a significant impact on identity and self-esteem 201. https://pubmed.ncbi.nlm.nih.gov/12729380/ 2. https://link.springer.com/article/10.1007/s13555-023-00925-z; https://pmc.ncbi.nlm.nih.gov/articles/PMC5414776/ 3. https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0057985 4. https://pmc.ncbi.nlm.nih.gov/articles/PMC5414776/ Eyebrow thinning is a sign of aging3 Reduction of eyebrow contrast is a sign of facial aging Eyebrows are important to facial identity1 Studies demonstrate eyebrows play a similar importance to facial recognition as eyes Eyebrow thinning impacts self- esteem2 Patient surveys indicate significant impact on QOL and self-esteem1 Eyebrows can be assessed on a 4- pt clinical scale4 GEBA scale has previously been utilized in topical latanoprost studies JULY 2026
Study ‘207’ Before and After Photos: “Sparse” Eyebrow Responder 21 JULY 2026 Month 6 Baseline Images represent a responder defined by at least a one-point increase on the GEBA scale for eyebrow fullness, assessed to have “sparse” eyebrows at baseline. Individual results may vary.
Study ‘207’ Before and After Photos: ”Sparse” Eyebrow Responder 22 JULY 2026 Month 6 Baseline Images represent a responder defined by at least a one-point increase on the GEBA scale for eyebrow fullness, assessed to have “sparse” eyebrows at baseline. Individual results may vary.
Study ‘207’: Female Safety and Tolerability 23
Study ‘207' demonstrated a well-tolerated safety profile • Overall safety and tolerability similar to prior trials with VDPHL01 with no new safety signals identified • No SAEs • No adverse events of special interest (AESI) of cardiac origin • No clinically significant changes in heart rate, blood pressure, or ECG observed • Lack of observed shedding 24 JULY 2026
Adverse Event Overview n(%) VDPHL01 4.5 mg (Pooled QD + BID) Any Treatment Emergent Adverse Events (TEAE) 15 (53.6) Any Treatment-Related TEAE 9 (32.1) TEAEs Leading to Study Discontinuation 1 (3.6)* Serious Adverse Events (SAE) 0 TEAE Severity Mild 9 (32.1) Moderate 6 (21.4) Severe 0 Most Common TEAE Peripheral Edema 2 (7.1) Hypertrichosis 6 (21.4) Study ‘207’ adverse event overview 25 *Note: Once case of hypertrichosis in the BID treatment group led to study discontinuation JULY 2026
26 VDPHL01 profile has the potential for differentiation across multiple key product characteristics Fast Consistent Intense Generally Well-Tolerated Convenient Oral Administration ~90% of participants reported ‘improved’ or ‘much improved’ at Month 6 (QD+BID) Average non-vellus hair count change of 22.7 / 23.3 hairs/cm2 at Month 6 (QD/BID) No SAEs; no AESIs of cardiac origin; generally consistent with prior VDPHL01 trials Favorable vs. topical alternatives1 63.2% of female participants reported improvement in hair coverage as early as Month 2 (QD+BID) 1Supported by third-party research Potential for the first ever FDA-approved oral option for female PHL JULY 2026
KOL Discussion Jerry Shapiro NYU Langone Health* 27 JULY 2026 *Dr. Jerry Shapiro is a paid consultant for Veradermics.
VDPHL01 Phase 2 FPHL Clinical Topline: FPHL Market Opportunity July 2026 Presented by: Mark Neumann, Chief Commercial and Strategy Officer
Insights on FPHL market opportunity have been refined through engagement with 500+ Patients and HCPs 29 342 Female Patients 272 HCPs Four market research studies, both qualitative and quantitative, conducted over last ~18 months provide a solid foundation on which to understand the opportunity for female PHL and the potential of VDPHL01 to address unmet needs1-4 Sources: 1. VDPHL Quantitative Study (n = 142 female patients, 150 HCPs), December 2024 2. Commercial Opportunity Assessment (102 HCPs ,134 female patients), May 2026 3. Patient Qualitative Segmentation Study (n = 50 female patients), May-June 2026 4. Female Qualitative Patient Journey Study (n = 10 female patients, n = 10 HCPs), June 2026 JULY 2026
FPHL impacts ~ 30 million1 women in the US and is poorly served by existing treatment options 30 32 30 16 8 0 5 10 15 20 25 30 35 Atopic Dermatitis (Eczema) PHL (Women) Rosacea Psoriasis Pa tie nt s Af fe ct ed in th e U .S .1 ( M ) 1American Academy of Dermatology. (n.d.). Skin conditions by the numbers. https://www.aad.org/media/stats/conditions/hair-loss 2 Source: Market research conducted November 2024; HCP n=150 patient n=410 No FDA-approved oral treatment options for FPHL FPHL patients are left to treat their hair loss with the existing assortment of off-label, unproven, or difficult to use treatment options2 JULY 2026
FPHL has a negative emotional effect that profoundly impacts patient quality of life 31 How Women Feel About PHL1 Women often feel devastated, sad, and anxious; many “cope rather than recover”2 Women said that hair was the single most important aesthetic category compared to things such as weight, skin, and teeth1 Women report that PHL has a high degree of negative daily impact on their lives2 Two-thirds of women reported that PHL is challenging to manage1 1Patient Qualitative Segmentation Study (n = 50 female patients), May-June 2026 2Female Qualitative Patient Journey Study (n = 10 female patients, n = 10 HCPs), June 2026 JULY 2026
FPHL patients are highly motivated and active treatment seekers with a high willingness to pay 32 High Willingness to Use Female patients express similar willingness to use VDPHL01 as males3; High HCP Willingness to Prescribe 73% of HCPs expressed that they were highly likely to prescribe VDPHL012 1Hwang HW, Ryou S, Jeong JH, Lee JW, Lee KJ, Lee SB, Shin HT, Byun JW, Shin J, Choi GS. The Quality of Life and Psychosocial Impact on Female Pattern Hair Loss. Ann Dermatol. 2024 Feb;36(1):44-52. doi: 10.5021/ad.23.082. PMID: 38325433; PMCID: PMC10861302. 2HCP Survey (N=100); Patient Survey (N=400) 3ClearView Analysis 2026. 4 https://pmc.ncbi.nlm.nih.gov/articles/PMC10149432/#CR5 – Minoxidil compliance and satisfaction High Willingness to Pay Female patients exposed to TPP similar to topline 302 data demonstrated higher willingness to pay than males3 Actively Seeking Treatment Females are more likely to seek treatment; lack of awareness of Rx options is a primary driver of OTC usage3 Significant Unmet Need 30M women in the U.S. with PHL with no oral FDA- approved treatment options Frequent Treatment Cycling 86% of topical minoxidil users discontinue treatment4 Impacted Quality of Life Patient surveys indicate women experience a greater impact on QOL than males with PHL 1 DRIVES DRIVES DRIVES JULY 2026
Acceptance of Suboptimal Tx Outcome or Discontinue FPHL patient journey suggests multiple opportunities to intervene with a novel prescription treatment option 33 ~MONTHS 0-122 ~MONTHS 6-12+2 POPULATION SIZE: (OTC ONLY) HCP visit; Rx Initiation (off-label) +/- OTC Frequent, Early OTC Cycling ~0.8M1POPULATION SIZE: (RX +/- OTC)~4.2M1 1Commercial Opportunity Assessment (102 HCPs ,134 female patients), May 2026 2Patient Qualitative Segmentation Study (n = 50 female patients), May-June 2026 ~MONTH 12+2 JULY 2026
FPHL patient satisfaction is low due to the limitations of current treatment options <20% of Female Patients Satisfied with Current Treatment Options Key limitations of current treatments: • No FDA-approved oral options • Limited hair regrowth • Slow onset of action • Cumbersome topical application • Side effects (Cardiac fears, shedding, leg swelling, hypertrichosis)0% of Female Patients tisfied with Current Treatment Options1,2 Patients are widely dissatisfied with generic IR oral minoxidil • 63% of those who have used it are not satisfied with its effectiveness1 1VDPHL Quantitative Study (n = 142 female patients, 150 HCPs), December 2024 2Commercial Opportunity Assessment (102 HCPs ,134 female patients), May 2026 JULY 2026 34
Women are looking for an efficacious, safe, oral treatment to address their FPHL 35 JULY 2026 Ideal Profile for a FPHL Treatment1 Demonstrated Efficacy Oral Administration Well- Characterized Safety Profile FDA Approval Rapid Onset of Action 1Commercial Opportunity Assessment (102 HCPs ,134 female patients), May 2026
Emerging VDPHL01 clinical profile from Phase 2 trial in FPHL demonstrated strong potential to deliver the attributes women are seeking 36 JULY 2026 Consistent response across participants • ~90% of participants reported ‘improved’ or ‘much improved’ at Month 6 (QD+BID) Rapid onset of effect • 63.2% of female participants reported improvement in hair coverage as early as Month 2 Robust increase in hair count • Average non-vellus hair count change of 22.7 / 23.3 hairs/cm2 at Month 6 (QD/BID) Well-characterized safety profile • No SAEs, no AESI of cardiac origin, favorable tolerability profile Convenient oral administration • Oral therapy avoids complications of topical treatments
Closing Remarks 37
Study ‘207’ results build conviction in VDPHL01 opportunity in FPHL ahead of registration-directed readout 38 Study ‘207’ signals potential for VDPHL01 as a first FDA- approved treatment for female PHL Proof of concept data increases conviction in upcoming Study ‘306’ Ph. 2/3 registration-directed female PHL readout and positions VDPHL01 to become the first and only FDA approved oral treatment for female PHL, if approved The female PHL market is large, underserved, and highly motivated ~30M women with limited treatment options for their hair loss Qualitative research highlights the profound impact of FPHL on quality of life Female PHL patients show dissatisfaction with current treatment options High discontinuation rates and treatment cycling indicate lack of a reliable patient journey to address FPHL, despite well- established willingnesss to pay across the aesthetics marketplace HCPs recognize need for better treatments to “change the conversation” around female PHL High-prevalence conditions with significant latent demand provide precedent for significant expansion of Rx opportunity with the introduction of a differentiated product JULY 2026
39 Patient voices highlight the unique impact of female pattern hair loss JULY 2026 “The scalp being exposed is so embarrassing, and it’s hard for me to be happy. I hate how people look at me and think I’m a monster. I just want to be normal like everyone else.” 1 “If I knew this worked, I would eat bologna sandwiches for a month… whatever it takes to pay for it.” 2 “Your face and your hair are your identity. When I lose my hair, I feel like I'm losing my identity” 3 “It brings me shame. I feel embarrassment. It's just overwhelming 3 “I would walk over hot coals and lie on a bed of tarantulas to get my hair back. So if it means taking a prescription — absolutely, yes” 3 1VDPHL Quantitative Study (n = 142 female patients, 150 HCPs), December 2024 2Commercial Opportunity Assessment (102 HCPs ,134 female patients), May 2026 3Female Qualitative Patient Journey Study (n = 10 female patients, n = 10 HCPs), June 2026
Meaningful Study ‘207’ results position VDPHL01 as a potential foundational treatment for PHL in females Upcoming Milestones Veradermics anticipates: • Male confirmatory Phase 3 data (Study ‘304’) in the second half of 2026; • Long-term extension male Ph. 2/3 data (Study ‘302 Part B) in the second half of 2026 • Female Phase 3 data (Study ‘306’) in the first half of 2027 40 Phase 2 proof of concept data support ongoing Phase 2/3 registrational clinical trial in women, the first ever Results delivered robust hair growth to patients who have grown accustomed to limitations when seeking to treat pattern hair loss Speed and consistency of effect further differentiate profile from current treatment options characterized by slow onset and varied outcomes JULY 2026
