MDxHealth holder reports 9.6% stake in shares

MDxHealth SA shareholder Laurence W. Lytton reports updated passive ownership of the company’s Ordinary Shares.

Rhea-AI Filing Summary

MDxHealth SA shareholder Laurence W. Lytton reports updated passive ownership of the company’s Ordinary Shares. Lytton beneficially owns 4,943,464 shares, representing 9.6% of the class, based on 51,364,520 Ordinary Shares outstanding as of December 31, 2025. Of this position, 3,533,783 shares are held with sole voting and dispositive power and 1,409,681 shares with shared voting and dispositive power.

Key Figures

Beneficially owned shares: 4,943,464 shares Percent of class: 9.6% Shares outstanding baseline: 51,364,520 shares +4 more

7 metrics

Beneficially owned shares 4,943,464 shares Ordinary Shares beneficially owned by Laurence W. Lytton

Percent of class 9.6% Ownership percentage of MDxHealth Ordinary Shares

Shares outstanding baseline 51,364,520 shares Ordinary Shares outstanding as of December 31, 2025

Sole voting power 3,533,783 shares Shares over which Lytton has sole power to vote

Shared voting power 1,409,681 shares Shares over which Lytton has shared power to vote

Sole dispositive power 3,533,783 shares Shares over which Lytton has sole power to dispose

Shared dispositive power 1,409,681 shares Shares over which Lytton has shared power to dispose

Key Terms

beneficially owned, Sole Voting Power, Shared Voting Power, Sole Dispositive Power, +1 more

5 terms

beneficially owned financial

"Amount beneficially owned: 4,943,464"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

Sole Voting Power financial

"Sole Voting Power 3,533,783.00"

Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.

Shared Voting Power financial

"Shared Voting Power 1,409,681.00"

Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.

Sole Dispositive Power financial

"Sole Dispositive Power 3,533,783.00"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

Shared Dispositive Power financial

"Shared Dispositive Power 1,409,681.00"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What percentage of MDXH does Laurence W. Lytton currently own?

Laurence W. Lytton beneficially owns 9.6% of MDxHealth SA’s Ordinary Shares. This is based on 4,943,464 shares compared with 51,364,520 shares outstanding as of December 31, 2025.

How many MDXH shares does Laurence W. Lytton report as beneficially owned?

Laurence W. Lytton reports beneficial ownership of 4,943,464 MDxHealth SA Ordinary Shares. This amount underlies his disclosed 9.6% ownership of the company’s outstanding Ordinary Shares.

What is the breakdown of sole versus shared voting power for MDXH shares held by Lytton?

Lytton reports 3,533,783 MDxHealth shares with sole voting power and 1,409,681 shares with shared voting power. The same breakdown applies to his sole and shared dispositive (sale) power.

On what share count is Laurence W. Lytton’s 9.6% MDXH ownership based?

The 9.6% ownership figure is calculated using 51,364,520 MDxHealth Ordinary Shares outstanding as of December 31, 2025, as reported in the company’s Form 20-F for that fiscal year.

What class of MDXH securities does Laurence W. Lytton hold?

Laurence W. Lytton holds MDxHealth SA Ordinary Shares. His Schedule 13G/A filing covers this single class, identified with CUSIP B5950S113 in the disclosure.

When was Laurence W. Lytton’s beneficial ownership report for MDXH signed?

The beneficial ownership report by Laurence W. Lytton regarding MDxHealth SA Ordinary Shares was signed on August 13, 2026 by the reporting person himself.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 08/13/2026 - 02:05 PM EDT Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 3)

MDxHealth SA

(Name of Issuer)

Ordinary Shares

(Title of Class of Securities)

B5950S113

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): B5950S113

1

Names of Reporting Persons

LYTTON LAURENCE W

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 3,533,783.00
6	Shared Voting Power 1,409,681.00
7	Sole Dispositive Power 3,533,783.00
8	Shared Dispositive Power 1,409,681.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

4,943,464.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

9.6 %

12

Type of Reporting Person (See Instructions)

IN

Comment for Type of Reporting Person: Percentage calculated based on 51,364,520 Ordinary Shares outstanding as of December 31, 2025, as reported in the Form 20-F filed by the Issuer for the fiscal year ended December 31, 2025.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: MDxHealth SA
(b)	Address of issuer's principal executive offices: CAP BUSINESS CENTER RUE D'ABHOOZ, 31, B-4040 HERSTAL, BELGIUM 00000
Item 2.
(a)	Name of person filing: Laurence W. Lytton
(b)	Address or principal business office or, if none, residence: 467 Central Park West New York, NY 10025
(c)	Citizenship: USA
(d)	Title of class of securities: Ordinary Shares
(e)	CUSIP No.: B5950S113
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 4,943,464
(b)	Percent of class: 9.6%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 3,533,783
	(ii) Shared power to vote or to direct the vote: 1,409,681
	(iii) Sole power to dispose or to direct the disposition of: 3,533,783
	(iv) Shared power to dispose or to direct the disposition of: 1,409,681
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

LYTTON LAURENCE W

Signature:	/s/ Laurence W. Lytton
Name/Title:	Reporting person
Date:	08/13/2026