STOCK TITAN

Director at Mineralys Therapeutics (MLYS) trades 3,000 shares under 10b5-1 plan

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Mineralys Therapeutics director Daphne Karydas exercised stock options for 3,000 shares of common stock at $12.02 per share and sold 3,000 shares at $25.00 per share. After these transactions, she holds 6,200 shares directly. The trades were executed under a pre-arranged Rule 10b5-1 trading plan adopted on December 30, 2025.

Positive

  • None.

Negative

  • None.
Insider Karydas Daphne
Role null
Sold 3,000 shs ($75K)
Type Security Shares Price Value
Exercise Stock Option 3,000 $0.00 --
Exercise Common Stock 3,000 $12.02 $36K
Sale Common Stock 3,000 $25.00 $75K
Holdings After Transaction: Stock Option — 38,000 shares (Direct, null); Common Stock — 9,200 shares (Direct, null)
Footnotes (1)
  1. These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted on December 30, 2025. The stock option vests in 36 monthly installments beginning on October 13, 2023.
Shares sold 3,000 shares Open-market sale of common stock on June 17, 2026
Sale price $25.00 per share Price for 3,000 Mineralys common shares sold
Options exercised 3,000 shares Stock options converted into common shares
Exercise price $12.02 per share Exercise price of stock options into common stock
Shares held after 6,200 shares Direct common stock holdings after transactions
Option expiration September 13, 2033 Original expiration date of exercised stock option grant
10b5-1 plan adoption December 30, 2025 Date the Rule 10b5-1 trading plan was adopted
Vesting schedule 36 monthly installments Stock option vests monthly starting October 13, 2023
Rule 10b5-1 trading plan regulatory
"These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted on December 30, 2025."
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
Stock Option financial
"security_title": "Stock Option""
A stock option is a contract that gives you the right to buy or sell a company's stock at a specific price within a certain time frame. People use them to potentially make money if the stock's price moves favorably or to protect against losses. It's like holding a coupon that can be used to buy or sell stock at a set price later on.
derivative security financial
"transaction_code_description": "Exercise or conversion of derivative security""
A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.
open-market sale financial
"transaction_action": "open-market sale""
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
expiration date financial
"expiration_date": "2033-09-13T00:00:00.000Z""
The expiration date is the deadline after which a financial contract, such as an option or a futures agreement, is no longer valid or can be exercised. It matters to investors because it determines the timeframe during which they can take action or benefit from the contract, similar to how a coupon or a food item has a limited period of usefulness. Once the expiration date passes, the contract loses its value or ability to be used.
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Karydas Daphne

(Last)(First)(Middle)
150 N. RADNOR CHESTER RD.
SUITE F200

(Street)
RADNOR PENNSYLVANIA 19087

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Mineralys Therapeutics, Inc. [ MLYS ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/17/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/17/2026M(1)3,000A$12.029,200D
Common Stock06/17/2026S(1)3,000D$256,200D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option$12.0206/17/2026M(1)3,000 (2)09/13/2033Common Stock3,000$038,000D
Explanation of Responses:
1. These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted on December 30, 2025.
2. The stock option vests in 36 monthly installments beginning on October 13, 2023.
Remarks:
/s/ Adam Levy, Attorney-in-fact06/17/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did Daphne Karydas report at Mineralys Therapeutics (MLYS)?

Daphne Karydas reported exercising stock options for 3,000 Mineralys Therapeutics shares and selling 3,000 common shares. These same-day transactions combined an option exercise with an open-market sale, while she retained a remaining direct holding after the trades.

At what prices did the Mineralys Therapeutics (MLYS) insider transactions occur?

Karydas exercised stock options at an exercise price of $12.02 per Mineralys share and sold 3,000 common shares at $25.00 per share. This reflects an exercise-and-sell pattern, turning option value into cash while maintaining a continuing equity position.

How many Mineralys Therapeutics (MLYS) shares does Daphne Karydas hold after the Form 4 trades?

After the reported transactions, Karydas holds 6,200 shares of Mineralys Therapeutics common stock directly. This figure reflects her remaining non-derivative equity position following the 3,000-share option exercise and the corresponding 3,000-share open-market sale on the same date.

Were the Mineralys Therapeutics (MLYS) insider trades made under a Rule 10b5-1 plan?

Yes, the transactions were executed under a pre-arranged Rule 10b5-1 trading plan adopted on December 30, 2025. Such plans schedule trades in advance, which can make the timing of the sale appear more routine rather than discretionary.

What stock options did Daphne Karydas exercise at Mineralys Therapeutics (MLYS)?

She exercised stock options covering 3,000 underlying shares of Mineralys common stock with a stated exercise price of $12.02 per share. The option grant vests in 36 monthly installments beginning on October 13, 2023, according to the disclosure footnote.

What happens to Daphne Karydas’ stock options after the reported Mineralys (MLYS) Form 4?

The filing shows a derivative transaction for 3,000 stock options exercised into common shares, with no remaining position for that grant in the derivative summary. The options had an expiration date of September 13, 2033 before exercise.