[SCHEDULE 13G] Mural Oncology plc SEC Filing

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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

Mural Oncology plc

(Name of Issuer)

Ordinary Shares, nominal value $0.01 per share

(Title of Class of Securities)

G63365103

(CUSIP Number)

06/23/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. G63365103

1

Names of Reporting Persons

Prosight Management, LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 900,000.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 900,000.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

900,000.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.2 %

12

Type of Reporting Person (See Instructions)

IA

Comment for Type of Reporting Person: The figure in Item 11 is based upon 17,268,881 Ordinary Shares, nominal value $0.01 per share ("Ordinary Shares") of Mural Oncology plc (the "Issuer") outstanding as of May 1, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the U.S. Securities and Exchange Commission (the "SEC") on May 14, 2025.

SCHEDULE 13G

CUSIP No. G63365103

1

Names of Reporting Persons

Prosight Fund, LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 51,390.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 51,390.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

51,390.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.3 %

12

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person: The figure in Item 11 is based upon 17,268,881 Ordinary Shares of the Issuer outstanding as of May 1, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the SEC on May 14, 2025.

SCHEDULE 13G

CUSIP No. G63365103

1

Names of Reporting Persons

Prosight Plus Fund, LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 196,625.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 196,625.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

196,625.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

1.1 %

12

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person: The figure in Item 11 is based upon 17,268,881 Ordinary Shares of the Issuer outstanding as of May 1, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the SEC on May 14, 2025.

SCHEDULE 13G

CUSIP No. G63365103

1

Names of Reporting Persons

Prosight Partners, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 900,000.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 900,000.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

900,000.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.2 %

12

Type of Reporting Person (See Instructions)

OO

Comment for Type of Reporting Person: The figure in Item 11 is based upon 17,268,881 Ordinary Shares of the Issuer outstanding as of May 1, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the SEC on May 14, 2025.

SCHEDULE 13G

CUSIP No. G63365103

1

Names of Reporting Persons

W. Lawrence Hawkins

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 900,000.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 900,000.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

900,000.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.2 %

12

Type of Reporting Person (See Instructions)

HC, IN

Comment for Type of Reporting Person: The figure in Item 11 is based upon 17,268,881 Ordinary Shares of the Issuer outstanding as of May 1, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the SEC on May 14, 2025.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Mural Oncology plc
(b)	Address of issuer's principal executive offices: 10 Earlsfort Terrace, Dublin 2, Ireland, D02 T380
Item 2.
(a)	Name of person filing: This statement is jointly filed by and on behalf of each of Prosight Management, LP, a Delaware limited partnership ("Prosight Management"), Prosight Fund, LP, a Delaware limited partnership ("Prosight Fund"), Prosight Plus Fund, LP, a Delaware limited partnership ("Prosight Plus Fund"), Prosight Partners, LLC, a Delaware limited liability company ("Prosight Partners"), and W. Lawrence Hawkins (collectively referred herein as the "Reporting Persons"). Prosight Management is the general partner and investment manager of, and may be deemed to indirectly beneficially own securities owned by, Prosight Fund and Prosight Plus Fund. Prosight Management is a sub-advisor for certain separate managed accounts (collectively, the "Managed Accounts") and may be deemed to indirectly beneficially own securities owned by the Managed Accounts. Prosight Partners is the general partner of, and may be deemed to beneficially own, securities beneficially owned by Prosight Management. Mr. Hawkins is the sole manager of, and may be deemed to beneficially own securities beneficially owned by, Prosight Partners. Prosight Fund, Prosight Plus Fund, and the Managed Accounts are the record and direct beneficial owner of the securities of the Issuer covered by this statement. Prosight Fund disclaims beneficial ownership of the securities of the Issuer held by each of the Managed Accounts and Prosight Plus Fund. Prosight Plus Fund disclaims beneficial ownership of the securities of the Issuer held by each of the Managed Accounts and Prosight Fund. Each Reporting Person declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Securities Exchange Act of 1934, as amended (the "Act") or any other purpose, the beneficial owner of any securities covered by this statement. Each Reporting Person may be deemed to be a member of a group with respect to the Issuer or securities of the Issuer for the purpose of Section 13(d) or 13(g) of the Act. Each of the Reporting Persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purpose of Section 13(d) or 13(g) of the Act or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate, or other group for the purpose of acquiring, holding, or disposing of securities of the Issuer or otherwise with respect to the Issuer or any securities of the Issuer or (ii) a member of any group with respect to the Issuer or any securities of the Issuer.
(b)	Address or principal business office or, if none, residence: The address of the principal business office of each of the Reporting Persons is c/o Prosight Management, LP, 5956 Sherry Lane, Suite 1365, Dallas, Texas 75225.
(c)	Citizenship: See Item 4 on the cover page(s) hereto.
(d)	Title of class of securities: Ordinary Shares, nominal value $0.01 per share
(e)	CUSIP No.: G63365103
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: See Item 9 on the cover pages hereto.
(b)	Percent of class: See Item 11 on the cover pages hereto.
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: See Item 5 on the cover pages hereto.
	(ii) Shared power to vote or to direct the vote: See Item 6 on the cover pages hereto.
	(iii) Sole power to dispose or to direct the disposition of: See Item 7 on the cover pages hereto.
	(iv) Shared power to dispose or to direct the disposition of: See Item 8 on the cover pages hereto.
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Prosight Management, LP

Signature:	Prosight Partners, LLC
Name/Title:	General Partner
Date:	06/26/2025

Signature:	/s/ W. Lawrence Hawkins
Name/Title:	Sole Manager of the General Partner
Date:	06/26/2025

Prosight Fund, LP

Signature:	Prosight Management, LP
Name/Title:	General Partner
Date:	06/26/2025

Signature:	Prosight Partners, LLC
Name/Title:	Sole Manager of the General Partner
Date:	06/26/2025

Signature:	/s/ W. Lawrence Hawkins
Name/Title:	Sole Manager of the General Partner of the General Partner
Date:	06/26/2025

Prosight Plus Fund, LP

Signature:	Prosight Management, LP
Name/Title:	General Partner
Date:	06/26/2025

Signature:	Prosight Partners, LLC
Name/Title:	General Partner of the General Partner
Date:	06/26/2025

Signature:	/s/ W. Lawrence Hawkins
Name/Title:	Sole Manager of the General Partner of the General Partner
Date:	06/26/2025

Prosight Partners, LLC

Signature:	/s/ W. Lawrence Hawkins
Name/Title:	Sole Manager
Date:	06/26/2025

W. Lawrence Hawkins

Signature:	/s/ W. Lawrence Hawkins
Name/Title:	W. Lawrence Hawkins
Date:	06/26/2025

Exhibit Information

Exhibit 99.1: Joint Filing Agreement (filed herewith).