Insider Parag Mallick holds 17.6% of Nautilus Biotechnology (NAUT)

Rhea-AI Filing Summary

Parag Mallick filed Amendment No. 2 to update his beneficial ownership of Nautilus Biotechnology common stock. He reports beneficial ownership of 22,557,411 shares, representing 17.6% of the company’s common stock, based on 126,564,473 shares outstanding plus his option shares.

The total includes 20,493,392 shares held directly, options to purchase 1,864,019 shares, and 200,000 shares held by The Dream Finder Foundation over which he and his spouse share voting and dispositive power. On March 2, 2026, he was granted an additional option to buy 280,000 shares, with vesting subject to continued service and full acceleration upon certain change-in-control termination events.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 2)

Nautilus Biotechnology, Inc.

(Name of Issuer)

Common stock, par value $0.0001 per share

(Title of Class of Securities)

Parag Mallick
2701 Eastlake Avenue East,
Seattle, WA, 98102
206-333-2001

Zachary B. Myers
Wilson Sonsini Goodrich & Rosati, 650 Page Mill Road
Palo Alto, CA, 94304
650-493-9300

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

03/02/2026

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

SCHEDULE 13D

CUSIP Number(s):

1

Name of reporting person

Parag Mallick

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

PF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 22,357,411.00
8	Shared Voting Power 200,000.00
9	Sole Dispositive Power 22,357,411.00
10	Shared Dispositive Power 200,000.00

11

Aggregate amount beneficially owned by each reporting person

22,557,411.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

17.6 %

14

Type of Reporting Person (See Instructions)

IN

Comment for Type of Reporting Person:

Items 7, 9, and 11 above consists of 20,493,392 shares of Common Stock directly owned by Parag Mallick and a total of 1,864,019 shares of Common Stock issuable upon exercise of options. Of such options to purchase shares, 1,234,018 shares shall be vested and exercisable within 60 days of March 2, 2026. Items 8, 10, and 11 above consists of 200,000 shares of Common Stock directly owned by The Dream Finder Foundation (the "Foundation"). Dr. Mallick and his spouse share voting and dispositive power over the shares held by the Foundation and Dr. Mallick is the President of the Foundation. Item 13 above is based on the quotient obtained by dividing (a) the aggregate number of shares of Common Stock beneficially owned by Dr. Mallick by (b) the sum of (i) 126,564,473 shares of Common Stock outstanding as of February 19, 2026, as reported in the Issuer's Form 10-K filed with the Securities and Exchange Commission on February 26, 2026, and (ii) the 1,864,019 shares of Common Stock issuable upon exercise of options held by Dr. Mallick. The aggregate number of shares of Common Stock beneficially owned by Dr. Mallick as set forth in clauses "(a)" and "(b)" of this footnote are treated as outstanding shares of Common Stock only for the purpose of computing the percentage ownership of Dr. Mallick.

SCHEDULE 13D

Item 1.	Security and Issuer
(a)	Title of Class of Securities: Common stock, par value $0.0001 per share
(b)	Name of Issuer: Nautilus Biotechnology, Inc.
(c)	Address of Issuer's Principal Executive Offices: 2701 Eastlake Avenue East, Seattle, WASHINGTON , 98102.
Item 1 Comment: This Amendment No. 2 (this "Amendment") amends and supplements the Schedule 13D filed on June 16, 2021, as amended by Amendment No. 1 filed on March 5, 2025 (the "Schedule 13D") by Parag Mallick (the "Reporting Person") relating to the Common Stock of Nautilus Biotechnology, Inc. (the "Issuer"). Information reported in the Schedule 13D remains in effect except to the extent that it is amended, restated or superseded by information contained in this Amendment. Capitalized terms used but not defined in this Amendment have the respective meanings set forth in the Schedule 13D. All references in the Schedule 13D and this Amendment shall be deemed to refer to the Schedule 13D as amended and supplemented by this Amendment.
Item 5.	Interest in Securities of the Issuer
(a)	As of the date of this Schedule 13D, the Reporting Person beneficially owns an aggregate of 22,557,411 shares of Common Stock, or 17.6% of the Issuer's outstanding shares of Common Stock. The beneficial ownership percentages used in this Schedule are calculated based on a total of 126,564,473 shares of Common Stock outstanding as of February 19, 2026 plus 1,864,019 shares of Common Stock issuable upon exercise of options held by the Reporting Person. 1,234,018 of the Reporting Person's options to purchase shares of Common Stock are exercisable within 60 days of March 2, 2026. The unvested options to purchase shares of Common Stock vest over time subject to the Reporting Person's continued service through each vesting date. If, during the period beginning three months before a change in control through the one-year anniversary of a change in control, the Reporting Person's employment with the Issuer is terminated either (x) by the Issuer without cause, and excluding by reason of the Reporting Person's death or disability or (y) by the Reporting Person for good reason, then 100% of any unvested shares shall immediately vest.
(b)	The Reporting Person and the Reporting Person's spouse share voting and dispositive power with respect to 200,000 shares of Common Stock owned by the Foundation. The Reporting Person has sole voting and dispositive power with respect to 20,493,392 shares of Common Stock and options to purchase 1,864,019 shares of Common Stock.
(c)	On March 2, 2026, the Reporting Person was granted an option to purchase 280,000 shares of the Issuer's Common Stock. Except for such option grant, the Reporting Person has not effected any transactions in the Common Stock during the past 60 days.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Parag Mallick

Signature:	/s/ Matthew Murphy
Name/Title:	Matthew Murphy/Attorney-in-fact
Date:	03/04/2026

FAQ

What percentage of Nautilus Biotechnology (NAUT) does Parag Mallick report owning?

Parag Mallick reports beneficial ownership of 17.6% of Nautilus Biotechnology’s common stock. This percentage is calculated using 126,564,473 shares outstanding as of February 19, 2026, plus 1,864,019 shares issuable upon exercise of his stock options.

How many Nautilus Biotechnology shares does Parag Mallick beneficially own?

Parag Mallick beneficially owns 22,557,411 Nautilus Biotechnology common shares. This consists of 20,493,392 shares held directly, options to purchase 1,864,019 shares, and 200,000 shares held by The Dream Finder Foundation over which he and his spouse share control.

What new stock option grant does Parag Mallick report in this Nautilus filing?

On March 2, 2026, Parag Mallick was granted an option to purchase 280,000 Nautilus Biotechnology common shares. The options vest over time with continued service, and all unvested shares fully vest if his employment ends under specified change-in-control termination conditions.

How many of Parag Mallick’s Nautilus options are currently exercisable?

Of Parag Mallick’s options, 1,234,018 Nautilus common share options are exercisable within 60 days of March 2, 2026. The remaining unvested options continue to vest over time, contingent on his ongoing service with Nautilus Biotechnology through each vesting date.

What role does The Dream Finder Foundation play in Parag Mallick’s NAUT holdings?

The Dream Finder Foundation holds 200,000 Nautilus common shares included in Parag Mallick’s beneficial ownership. Mallick and his spouse share voting and dispositive power over these shares, and he serves as President of the Foundation, giving him shared control over that block.

How is Parag Mallick’s 17.6% Nautilus ownership percentage calculated?

The 17.6% figure is based on 126,564,473 Nautilus shares outstanding as of February 19, 2026, plus 1,864,019 shares issuable upon exercise of Mallick’s options. His 22,557,411 beneficially owned shares are divided by this combined total to determine the percentage.