Redmile Group (NRIX) discloses 8.1% Nurix stake including pre-funded warrants

Rhea-AI Filing Summary

Redmile Group, LLC and related entities report significant ownership in Nurix Therapeutics, Inc. Redmile Group, LLC and its principal, Jeremy C. Green, each report beneficial ownership of 8,782,256 shares of Nurix common stock, representing 8.1% of the class. This stake consists of 4,073,787 outstanding shares and 4,708,469 shares issuable upon exercise of pre-funded warrants held by investment vehicles managed by Redmile. RedCo II Offshore SPV LLC, one such vehicle, reports beneficial ownership of 3,712,546 shares, or 3.5%, including shares issuable upon warrant exercise. Beneficial ownership percentages are based on 103,781,683 shares outstanding as of June 30, 2026, plus the relevant warrant shares. Voting and dispositive powers are reported as shared, with Redmile and Mr. Green disclaiming beneficial ownership beyond their pecuniary interest.

Key Figures

Beneficial ownership – Redmile Group, LLC: 8,782,256 shares Beneficial ownership – Jeremy C. Green: 8,782,256 shares Beneficial ownership – RedCo II Offshore SPV LLC: 3,712,546 shares +3 more

6 metrics

Beneficial ownership – Redmile Group, LLC 8,782,256 shares Nurix common stock beneficially owned, as of June 30, 2026

Beneficial ownership – Jeremy C. Green 8,782,256 shares Nurix common stock beneficially owned, mirroring Redmile’s reported position

Beneficial ownership – RedCo II Offshore SPV LLC 3,712,546 shares Nurix common stock beneficially owned through shares and warrants

Ownership percentage – Redmile/Jeremy C. Green 8.1% Percent of Nurix common stock class, including 4,708,469 warrant shares

Ownership percentage – RedCo II Offshore 3.5% Percent of Nurix common stock class, including 2,881,142 warrant shares

Shares outstanding baseline 103,781,683 shares Nurix common stock outstanding as of June 30, 2026 per Form 10-Q

Key Terms

beneficially own, pre-funded warrants, shared voting power, shared dispositive power, +1 more

5 terms

beneficially own financial

"Amount beneficially owned: Redmile Group, LLC - 8,782,256"

Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.

pre-funded warrants financial

"shares of Common Stock issuable upon exercise of certain pre-funded warrants"

Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.

shared voting power financial

"Shared Voting Power 8,782,256.00"

Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.

shared dispositive power financial

"Shared Dispositive Power 8,782,256.00"

Schedule 13G regulatory

"If a parent holding company has filed this schedule, pursuant to"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

FAQ

What ownership stake in Nurix Therapeutics (NRIX) does Redmile Group report?

Redmile Group, LLC and Jeremy C. Green each report beneficial ownership of 8,782,256 shares of Nurix common stock, representing 8.1% of the outstanding class, including shares underlying pre-funded warrants managed through Redmile investment funds.

How many Nurix (NRIX) shares does RedCo II Offshore SPV LLC beneficially own?

RedCo II Offshore SPV LLC reports beneficial ownership of 3,712,546 shares of Nurix common stock, representing 3.5% of the class. This includes 831,404 outstanding shares and 2,881,142 shares issuable upon exercise of pre-funded warrants it directly holds.

How are Redmile’s Nurix (NRIX) holdings structured between stock and warrants?

Redmile’s reported beneficial ownership includes 4,073,787 outstanding Nurix common shares and 4,708,469 shares issuable upon exercise of pre-funded warrants. These securities are held by various Redmile-managed funds, including RedCo II Offshore SPV LLC, for which Redmile acts as investment manager.

What share count underlies the ownership percentages in this Nurix (NRIX) Schedule 13G/A?

The reported ownership percentages use a base of 103,781,683 Nurix common shares outstanding as of June 30, 2026, as disclosed in Nurix’s Form 10-Q, plus the additional shares issuable upon exercise of the relevant pre-funded warrants held by Redmile-managed funds.

Do Redmile Group and Jeremy C. Green have sole or shared voting power over Nurix (NRIX) shares?

Redmile Group and Jeremy C. Green report 0 shares with sole voting or dispositive power and 8,782,256 shares with shared voting and dispositive power, reflecting their roles as investment manager and principal of the Redmile-managed funds holding the Nurix securities.

Do Redmile Group and Jeremy C. Green disclaim any Nurix (NRIX) beneficial ownership?

Yes. Redmile Group and Jeremy C. Green state they disclaim beneficial ownership of the Nurix securities held by the Redmile funds, except to the extent of their pecuniary interest in such securities, if any, despite reporting them as beneficially owned for Schedule 13G purposes.

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Available on EDGAR 08/14/2026 - 04:25 PM Accepted by SEC EDGAR 08/14/2026 - 04:17 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 6)

Nurix Therapeutics, Inc.

(Name of Issuer)

Common Stock, par value $0.001 per share

(Title of Class of Securities)

67080M103

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 67080M103

1

Names of Reporting Persons

Redmile Group, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 8,782,256.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 8,782,256.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

8,782,256.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.1 %

12

Type of Reporting Person (See Instructions)

IA, OO

Comment for Type of Reporting Person: The information in Item 4 relating to the shares of the Issuer's common stock, par value $0.001 per share ("Common Stock"), that are or may be deemed beneficially owned by Redmile Group, LLC and the calculation of the percent of such class of securities is incorporated herein by reference.

SCHEDULE 13G

CUSIP Number(s): 67080M103

1

Names of Reporting Persons

Jeremy C. Green

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED KINGDOM

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 8,782,256.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 8,782,256.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

8,782,256.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.1 %

12

Type of Reporting Person (See Instructions)

HC, IN

Comment for Type of Reporting Person: The information in Item 4 relating to the shares of Common Stock that are or may be deemed beneficially owned by Jeremy C. Green and the calculation of the percent of such class of securities is incorporated herein by reference.

SCHEDULE 13G

CUSIP Number(s): 67080M103

1

Names of Reporting Persons

RedCo II Offshore SPV LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 3,712,546.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 3,712,546.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

3,712,546.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

3.5 %

12

Type of Reporting Person (See Instructions)

FI, OO

Comment for Type of Reporting Person: The information in Item 4 relating to the shares of Common Stock that are or may be deemed beneficially owned by RedCo II Offshore SPV LLC and the calculation of the percent of such class of securities is incorporated herein by reference.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Nurix Therapeutics, Inc.
(b)	Address of issuer's principal executive offices: 1600 Sierra Point Parkway, Brisbane, CA 94005
Item 2.
(a)	Name of person filing: Redmile Group, LLC Jeremy C. Green RedCo II Offshore SPV LLC
(b)	Address or principal business office or, if none, residence: Redmile Group, LLC 900 Larkspur Landing Circle, Suite 270 Larkspur, California 94939 Jeremy C. Green c/o Redmile Group, LLC (NY Office) 45 W. 27th Street, Floor 11 New York, NY 10001 RedCo II Offshore SPV LLC c/o Redmile Group, LLC 900 Larkspur Landing Circle, Suite 270 Larkspur, California 94939
(c)	Citizenship: Redmile Group, LLC: Delaware Jeremy C. Green: United Kingdom RedCo II Offshore SPV LLC: Cayman Islands
(d)	Title of class of securities: Common Stock, par value $0.001 per share
(e)	CUSIP No.: 67080M103
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: Redmile Group, LLC - 8,782,256 (1) Jeremy C. Green - 8,782,256 (1) RedCo II Offshore SPV LLC - 3,712,546 (2)
(b)	Percent of class: Redmile Group, LLC - 8.1% (3) Jeremy C. Green - 8.1% (3) RedCo II Offshore SPV LLC - 3.5% (4)
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: Redmile Group, LLC - 0 Jeremy C. Green - 0 RedCo II Offshore SPV LLC - 0
	(ii) Shared power to vote or to direct the vote: Redmile Group, LLC - 8,782,256 (1) Jeremy C. Green - 8,782,256 (1) RedCo II Offshore SPV LLC - 3,712,546 (2)
	(iii) Sole power to dispose or to direct the disposition of: Redmile Group, LLC - 0 Jeremy C. Green - 0 RedCo II Offshore SPV LLC - 0
	(iv) Shared power to dispose or to direct the disposition of: Redmile Group, LLC - 8,782,256 (1) Jeremy C. Green - 8,782,256 (1) RedCo II Offshore SPV LLC - 3,712,546 (2) (1) Redmile's and Jeremy C. Green's beneficial ownership of the Issuer's Common Stock is comprised of (i) 4,073,787 shares of Common Stock and (ii) 4,708,469 shares of Common Stock issuable upon exercise of certain pre-funded warrants to purchase Common Stock (the "Warrants"). All of such shares of Common Stock and the Warrants are directly owned by certain investment vehicles, including RedCo II Offshore SPV LLC ("RedCo II Offshore"), for which Redmile is the investment manager (the "Redmile Funds"). Redmile may be deemed to beneficially own these securities in its capacity as their investment manager with discretion to vote and dispose of all shares of Common Stock held by the Redmile Funds. Mr. Green also may be deemed to beneficially own these securities as the principal of Redmile. Redmile and Mr. Green each disclaims beneficial ownership of these securities, except to the extent of its or his pecuniary interest in such securities, if any. (2) RedCo II Offshore may be deemed to beneficially own (i) 831,404 shares of Common Stock, and (ii) 2,881,142 shares of Common Stock issuable upon exercise of the Warrants directly held by RedCo II Offshore. (3) Percentage for Redmile and Jeremy Green based on (i) 103,781,683 shares of Common Stock outstanding as of June 30, 2026, as reported by the Issuer in its Form 10-Q for the quarterly period ended May 31, 2026 filed with the SEC on July 9, 2026 (the "Form 10-Q"), plus (ii) 4,708,469 shares of Common Stock issuable upon exercise of certain of the Warrants held directly by the Redmile Funds, including RedCo II Offshore. (4) Percentage for RedCo II Offshore based on (i) 103,781,683 shares of Common Stock outstanding as of June 30, 2026, as reported by the Issuer in its Form 10-Q, plus (ii) 2,881,142 shares of Common Stock issuable upon exercise of certain of the Warrants held directly by RedCo II Offshore.
Item 5.	Ownership of 5 Percent or Less of a Class.
	Ownership of 5 percent or less of a class
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See the response to Item 4.
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Redmile Group, LLC

Signature:	/s/ Jeremy C. Green
Name/Title:	Managing Member
Date:	08/14/2026

Jeremy C. Green

Signature:	/s/ Jeremy C. Green
Name/Title:	Jeremy C. Green
Date:	08/14/2026

RedCo II Offshore SPV LLC

Signature:	/s/ Jeremy C. Green
Name/Title:	Managing Member of Redmile Group, LLC, its manager
Date:	08/14/2026