Welcome to our dedicated page for Orchestra BioMed Holdings SEC filings (Ticker: OBIO), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Orchestra BioMed Holdings, Inc. filings document the governance, financing and material agreements of a biomedical company developing AVIM Therapy and Virtue SAB through strategic medical-device partnerships. Current reports describe revenue participation rights, strategic financing, distribution and right-of-first-refusal arrangements, underwritten common stock and pre-funded warrant offerings, investor presentations, and other business updates.
Proxy materials cover board elections, auditor ratification, executive compensation votes, equity and employee stock purchase plans, and related annual-meeting governance. The filing record also includes compensatory-arrangement disclosures for executive bonus plans, registration-statement references, exhibit filings and capital-structure disclosure tied to its cardiovascular product candidates.
Orchestra BioMed Holdings director Aryeh Jason made a small open-market purchase of company stock. On May 18, 2026, he bought 665 shares of common stock at a weighted average price of about $3.75–$3.76 per share. After this transaction, he directly owns 118,118 shares.
Orchestra BioMed Holdings director Jason Aryeh bought additional company stock in the open market. On May 15, 2026, he purchased 8,971 shares of common stock at a weighted average price of $3.90 per share, through multiple trades priced between $3.70 and $4.03.
Following this transaction, Aryeh directly owns 117,453 shares of Orchestra BioMed common stock. The filing notes that detailed trade-by-trade pricing within this range is available on request from the company, its shareholders, or the SEC staff.
Orchestra BioMed Holdings, Inc. director and officer David P. Hochman reported an open-market purchase of 5,000 shares of Common Stock on May 15, 2026 at a weighted average price of $3.77 per share. Following this purchase, he directly holds 1,059,029 shares of Common Stock.
The filing also lists indirect holdings through several family trusts, including 439,482 shares held by the DPH 2008 Trust and smaller positions held by the NSH 2008 Family Trust and three 2019 trusts.
Orchestra BioMed Holdings director Eric S. Fain, through the Fain Living Trust, bought 20,000 shares of common stock in an open-market purchase on May 14, 2026 at a weighted average price of $4.13 per share. Following this transaction, the trust holds 91,709 shares indirectly.
Orchestra BioMed Holdings, Inc. reported a Q1 2026 net loss attributable to common stockholders of $20.7 million, or $0.33 per share, compared with a $18.8 million loss a year earlier.
Total revenue fell to $0.1 million, primarily from product sales, after partnership revenue dropped to zero from $0.7 million. Operating expenses increased to $22.2 million, driven by higher research and development spending of $15.8 million and selling, general and administrative costs of $6.4 million.
At March 31, 2026, the company held $28.4 million in cash and cash equivalents and $66.0 million in marketable securities, with total assets of $100.7 million and stockholders’ equity of $41.2 million. Management states that existing cash, securities and contractual financing commitments are sufficient to fund operations for at least one year after the financial statements’ issuance date.
Orchestra BioMed Holdings, Inc. reported a Q1 2026 net loss attributable to common stockholders of $20.7 million, or $0.33 per share, compared with a $18.8 million loss a year earlier.
Total revenue fell to $0.1 million, primarily from product sales, after partnership revenue dropped to zero from $0.7 million. Operating expenses increased to $22.2 million, driven by higher research and development spending of $15.8 million and selling, general and administrative costs of $6.4 million.
At March 31, 2026, the company held $28.4 million in cash and cash equivalents and $66.0 million in marketable securities, with total assets of $100.7 million and stockholders’ equity of $41.2 million. Management states that existing cash, securities and contractual financing commitments are sufficient to fund operations for at least one year after the financial statements’ issuance date.
RTW Investments and affiliated funds updated their ownership report on Orchestra BioMed Holdings after exercising pre-funded warrants. On April 27, 2026, the RTW funds exercised pre-funded warrants for 1,250,032 shares at $0.0001 per share on a cashless basis, leading to 1,250,000 new common shares being issued and 32 shares withheld to cover the exercise price.
Following these transactions and including certain additional warrants exercisable within 60 days, RTW Investments and Dr. Roderick Wong are reported as beneficial owners of 11,942,394 shares of common stock, representing 19.2% of Orchestra BioMed’s outstanding common stock as calculated in the filing.
Orchestra BioMed Holdings, Inc. reported that affiliated RTW funds exercised pre-funded warrants to acquire 1,250,032 shares of common stock at $0.0001 per share on a cashless basis. The issuer withheld 32 shares to satisfy the exercise price and issued 1,250,000 shares to the RTW funds.
After the transactions, the reporting parties indirectly held 9,556,095 shares of common stock and 2,386,331 pre-funded warrants. The RTW funds and their attribution parties are limited to beneficial ownership of no more than 19.99% of outstanding common stock following any exercise, and the reporting persons disclaim beneficial ownership except to the extent of their pecuniary interest.
Orchestra BioMed Holdings, Inc. is asking stockholders to vote at its 2026 virtual annual meeting on June 23, 2026. The agenda includes electing three Class III directors, ratifying Ernst & Young LLP as auditor, and advisory votes on executive pay and pay frequency.
The company also seeks approval of a 2026 Employee Stock Purchase Plan authorizing up to 750,000 shares, which it estimates represents about 1.25% overhang based on 59,880,715 shares outstanding as of April 28, 2026. The meeting will be held online via live audio webcast, with full voting and Q&A participation rights.
Orchestra BioMed Holdings director and officer Darren Sherman reported a tax-related share disposition linked to restricted stock units. On the vesting of RSUs, the company withheld 33,317 shares of common stock at an effective price of $4.57 per share to cover tax obligations. According to the filing, no shares were sold in the market in connection with this event. After this withholding, Sherman directly holds 1,204,252 shares of Orchestra BioMed common stock.