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Tax-driven ADS sale by BeOne Medicines (ONC) CEO after RSU vesting

Filing Impact
(Very High)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

BeOne Medicines Ltd. Chief Executive Officer John Oyler reported tax-related transactions in American Depositary Shares (ADSs). On June 8, 2026, a total of 4,940 ADSs were sold at weighted average prices of about $270–$271 per ADS. A footnote explains the sale was carried out under a mandatory tax withholding provision connected to the vesting of a previously granted restricted share unit award, rather than a discretionary open-market sale. Each ADS represents 13 Ordinary Shares. Following these transactions, Oyler held no ADSs directly, but continued to have substantial Ordinary Share holdings directly and through various trusts and entities, some of which he disclaims beneficial ownership in the footnotes.

Positive

  • None.

Negative

  • None.
Insider OYLER JOHN
Role Chief Executive Officer
Sold 4,940 shs ($1.34M)
Type Security Shares Price Value
Sale American Depositary Shares 3,820 $270.3847 $1.03M
Sale American Depositary Shares 1,120 $271.1411 $304K
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
Holdings After Transaction: American Depositary Shares — 1,120 shares (Direct, null); Ordinary Shares — 5,545,055 shares (Direct, null); Ordinary Shares — 481,533 shares (Indirect, See Footnote)
Footnotes (1)
  1. These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. These securities are held by Oyler Investment LLC, of which 99% of the the limited liability company interest owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's minor child, for which the Reporting Person disclaims beneficial ownership. Each American Depositary Share represents 13 Ordinary Shares The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a restricted share unit award previously granted to the Reporting Person. 1/4th of the securities will vest on each anniversary of June 5, 2024, subject to continued service. Unvested securities are subject to accelerated vesting upon change of control or certain termination events. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $269.89 to $270.86, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $270.98 to $271.24, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
ADSs sold 4,940 ADSs Total American Depositary Shares sold on June 8, 2026
ADS block sale 1 3,820 ADSs at $270.3847 Weighted average price for one sale block
ADS block sale 2 1,120 ADSs at $271.1411 Weighted average price for second sale block
ADS to Ordinary Share ratio 1 ADS = 13 Ordinary Shares Economic equivalence disclosed in footnote
Direct Ordinary Shares 5,545,055 Ordinary Shares Direct Ordinary Share holdings after transactions
Indirect Ordinary Shares example 28,204,115 Ordinary Shares One indirect Ordinary Share holding balance with disclaimer
Holding entry example 102,188 Ordinary Shares Indirect Ordinary Share balance in a trust
American Depositary Shares financial
"The sale involved American Depositary Shares, each representing 13 Ordinary Shares"
American depositary shares (ADSs) are a way for investors in the United States to buy shares of foreign companies without dealing with international markets directly. They represent ownership in a foreign company's stock and are traded on U.S. stock exchanges, making it easier for American investors to buy, sell, and own parts of companies from around the world.
grantor retained annuity trust financial
"These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee"
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
Roth IRA financial
"These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account"
A Roth IRA is a retirement savings account you fund with money that’s already been taxed, and withdrawals taken in retirement under the account rules are tax-free. It matters to investors because it shifts the tax bill to today instead of retirement, potentially increasing after-tax income later—think of it like paying for a lifetime subscription now so you can use it without extra charges in the future—helpful for long-term tax planning and flexibility.
mandatory tax withholding financial
"The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement"
restricted share unit award financial
"in connection with the vesting of a restricted share unit award previously granted to the Reporting Person"
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
OYLER JOHN

(Last)(First)(Middle)
C/O BEONE MEDICINES I GMBH
AESCHENGRABEN 27, 21ST FLOOR

(Street)
BASEL4051

(City)(State)(Zip)

SWITZERLAND

(Country)
2. Issuer Name and Ticker or Trading Symbol
BeOne Medicines Ltd. [ ONC ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Chief Executive Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/08/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares5,545,055D
Ordinary Shares481,533ISee Footnote(1)
Ordinary Shares7,699,158ISee Footnote(2)
Ordinary Shares28,204,115ISee Footnote(3)
Ordinary Shares9,545,000ISee Footnote(4)
Ordinary Shares102,188ISee Footnote(5)
American Depositary Shares(6)06/08/2026S(7)3,820D$270.3847(8)1,120D
American Depositary Shares(6)06/08/2026S(7)1,120D$271.1411(9)0D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.
2. These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
3. These securities are held by Oyler Investment LLC, of which 99% of the the limited liability company interest owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
4. These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.
5. These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's minor child, for which the Reporting Person disclaims beneficial ownership.
6. Each American Depositary Share represents 13 Ordinary Shares
7. The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a restricted share unit award previously granted to the Reporting Person. 1/4th of the securities will vest on each anniversary of June 5, 2024, subject to continued service. Unvested securities are subject to accelerated vesting upon change of control or certain termination events.
8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $269.89 to $270.86, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $270.98 to $271.24, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
Remarks:
/s/ Qing Nian, as Attorney-in-Fact06/10/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transaction did BeOne Medicines (ONC) report for its CEO?

BeOne Medicines CEO John Oyler reported selling 4,940 American Depositary Shares. The sale was executed to satisfy mandatory tax withholding obligations tied to vesting restricted share units, rather than as a discretionary open-market trade.

How many BeOne Medicines (ONC) ADSs did the CEO sell and at what prices?

John Oyler sold 4,940 American Depositary Shares in two blocks: 3,820 ADSs at a weighted average price of $270.3847 and 1,120 ADSs at $271.1411. Both blocks were reported as open-market sales on June 8, 2026.

Why were BeOne Medicines (ONC) ADSs sold by the CEO according to the filing?

The ADS sale was made under a mandatory tax withholding provision linked to a restricted share unit award. When the RSUs vested, shares were sold to cover associated tax obligations, rather than representing a voluntary reduction of the CEO’s investment position.

What is the ADS to Ordinary Share ratio for BeOne Medicines (ONC)?

Each BeOne Medicines American Depositary Share represents 13 Ordinary Shares. This ratio means the 4,940 ADSs involved in the tax-related sale correspond economically to a significantly larger number of underlying Ordinary Shares, as specified in the footnotes.

Does the BeOne Medicines (ONC) CEO still hold shares after this ADS sale?

Yes. After the tax-related ADS sale, John Oyler reported no direct ADS holdings but continued to hold millions of Ordinary Shares directly and through several trusts and entities, with beneficial ownership of some indirect positions expressly disclaimed in the footnotes.

How do the CEO’s RSUs at BeOne Medicines (ONC) vest over time?

The restricted share unit award vests in four equal installments, with one-quarter vesting on each anniversary of June 5, 2024. Unvested RSUs may vest earlier upon a change of control or certain qualifying termination events, as described in the footnote.