STOCK TITAN

BeOne director sells 38K ADS after option exercise

BeOne Medicines director Wang Xiaodong exercised options and sold ADSs under a Rule 10b5-1 plan while retaining a large ordinary share position.

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Form Type
4

Rhea-AI Filing Summary

BeOne Medicines Ltd. (ONC) director and Scientific Advisory Board chair Wang Xiaodong reported multiple equity transactions on September 8, 2026. He exercised options covering 403,351 Ordinary Shares at an exercise price of $2.84 per share, leaving options on 1,210,079 Ordinary Shares outstanding. On the same date, he acquired 31,027 American Depositary Shares (ADS) (each ADS representing 13 Ordinary Shares) through an exercise or conversion and sold a total of 38,287 ADS in a series of open-market transactions at weighted-average prices in the mid-$300s per ADS, executed under a Rule 10b5-1 trading plan adopted on June 9, 2026. Following these transactions, he directly held 4,588,113 Ordinary Shares and also had indirect interests through family-related entities and a family trust, for which he disclaims beneficial ownership.

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Insider Wang Xiaodong
Role Director
Sold 38,287 shs ($13.37M)
Approx. gross sale proceeds $13.37M
Approx. exercise cost $1.15M
Type Security Shares Price Value
Exercise Share Option (Right to Buy) F14, F15 403,351 $0.00 $0.00
Sale American Depositary Shares F4, F5, F6 1,181 $345.383 $408K
Sale American Depositary Shares F4, F5, F7 2,841 $346.1575 $983K
Sale American Depositary Shares F4, F5, F8 1,517 $347.3915 $527K
Sale American Depositary Shares F4, F5, F9 1,721 $348.0126 $599K
Exercise American Depositary Shares F4 31,027 $36.90 $1.14M
Sale American Depositary Shares F4, F5, F10 7,492 $348.3146 $2.61M
Sale American Depositary Shares F4, F5, F11 10,688 $349.2834 $3.73M
Sale American Depositary Shares F4, F5, F12 6,569 $350.2741 $2.30M
Sale American Depositary Shares F4, F5, F13 6,278 $351.2542 $2.21M
holding Ordinary Shares -- -- --
holding Ordinary Shares F1 -- -- --
holding Ordinary Shares F2 -- -- --
holding Ordinary Shares F3 -- -- --
Holdings After Transaction: Share Option (Right to Buy) — 1,210,079 contracts (Direct); American Depositary Shares — 0 shares (Direct); Ordinary Shares — 4,588,113 shares (Direct); Ordinary Shares — 4,978,213 shares (Indirect, See Footnote)
Footnotes (15)
  1. F1. These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.
  2. F2. These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.
  3. F3. These securities are held by the spouse of the Reporting Person.
  4. F4. Each American Depositary Share represents 13 Ordinary Shares.
  5. F5. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.
  6. F6. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $344.71 to $345.66, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  7. F7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $345.71 to $346.70, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  8. F8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $346.79 to $347.78, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  9. F9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $347.80 to $348.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  10. F10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $348.07 to $348.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  11. F11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $348.80 to $349.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  12. F12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $349.81 to $350.80, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  13. F13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $350.82 to $351.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  14. F14. The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.
  15. F15. These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.
Options exercised 403,351 Ordinary Shares Share options exercised by Wang Xiaodong on September 8, 2026
Option exercise price $2.84 per Ordinary Share Exercise price for 403,351 Ordinary Shares underlying options
ADS acquired via exercise/conversion 31,027 ADS American Depositary Shares acquired on September 8, 2026
ADS sold 38,287 ADS Total American Depositary Shares sold across reported transactions
ADS-to-Ordinary Share ratio 1 ADS : 13 Ordinary Shares Ratio stated for BeOne Medicines American Depositary Shares
Direct Ordinary Shares after transactions 4,588,113 Ordinary Shares Direct holdings of Wang Xiaodong following reported transactions
Options outstanding after exercise 1,210,079 Ordinary Shares Ordinary Shares underlying options remaining after the reported exercise
ADS exercise/conversion price $36.90 per ADS Reported price for acquisition of 31,027 American Depositary Shares
Rule 10b5-1 trading plan regulatory
"The sale was effected pursuant to a Rule 10b5-1 trading plan adopted"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
American Depositary Shares financial
"Each American Depositary Share represents 13 Ordinary Shares."
American depositary shares (ADSs) are a way for investors in the United States to buy shares of foreign companies without dealing with international markets directly. They represent ownership in a foreign company's stock and are traded on U.S. stock exchanges, making it easier for American investors to buy, sell, and own parts of companies from around the world.
grantor retained annuity trusts financial
"owned by two grantor retained annuity trusts, of which the Reporting"
A grantor retained annuity trust (GRAT) is an estate-planning tool where an owner transfers assets into a trust and receives fixed payments back for a set number of years; any remaining assets after that period pass to designated beneficiaries. For investors it matters because it can move future investment growth to heirs while potentially reducing gift and estate taxes — like putting a rising asset in a timed box that pays you first and gives the remaining upside to others.
weighted average price financial
"The price reported in Column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
beneficial ownership regulatory
"for which the Reporting Person disclaims beneficial ownership."
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

FAQ

What insider transactions did ONC director Wang Xiaodong report on September 8, 2026?

Wang Xiaodong reported exercising options for 403,351 Ordinary Shares at $2.84 per share, acquiring 31,027 ADS and selling a total of 38,287 ADS in multiple open-market transactions at weighted-average prices in the mid-$300s per ADS.

How many BeOne Medicines (ONC) options did Wang Xiaodong exercise and what was the strike price?

He exercised options covering 403,351 Ordinary Shares of BeOne Medicines at an exercise price of $2.84 per share. These options were part of a grant that vests over four years, with unvested portions subject to accelerated vesting upon certain termination events.

How many American Depositary Shares of ONC did Wang Xiaodong sell in this Form 4?

He sold a total of 38,287 American Depositary Shares (ADS) on September 8, 2026, across several transactions. Each sale was reported with a weighted-average price, with price ranges from approximately $344.71 to $351.74 per ADS.

Were Wang Xiaodong’s ONC share sales made under a Rule 10b5-1 trading plan?

Yes. The filing states that the reported ADS sales were effected pursuant to a Rule 10b5-1 trading plan adopted by Wang Xiaodong on June 9, 2026, indicating a pre-arranged framework for executing these transactions.

What is Wang Xiaodong’s direct shareholding in BeOne Medicines (ONC) after these transactions?

After the reported transactions, Wang Xiaodong directly held 4,588,113 Ordinary Shares of BeOne Medicines. He also has additional indirect interests through a family trust, an LLC tied to grantor retained annuity trusts, and his spouse’s holdings, which he disclaims beneficial ownership of.

How many BeOne Medicines options does Wang Xiaodong still hold after the Form 4 transactions?

Following the option exercise reported, he continued to hold options on 1,210,079 Ordinary Shares. These options relate to grants that vest over time and may be subject to accelerated vesting upon certain termination events as described in the footnotes.

What is the relationship between ONC’s American Depositary Shares and Ordinary Shares in this filing?

The filing states that each American Depositary Share represents 13 Ordinary Shares of BeOne Medicines. This ratio applies to all ADS transactions reported for Wang Xiaodong in the Form 4.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Wang Xiaodong

(Last)(First)(Middle)
C/O BEONE MEDICINES I GMBH
AESCHENGRABEN 27, 21ST FLOOR

(Street)
BASEL4051

(City)(State)(Zip)

SWITZERLAND

(Country)
2. Issuer Name and Ticker or Trading Symbol
BeOne Medicines Ltd. [ ONC ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)XOther (specify below)
Chair, Scientific Advisory Brd
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
09/08/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares4,588,113D
Ordinary Shares1,025,063ISee Footnote(1)
Ordinary Shares3,953,100ISee Footnote(2)
Ordinary Shares50ISee Footnote(3)
American Depositary Shares(4)09/08/2026S(5)1,181D$345.383(6)6,079D
American Depositary Shares(4)09/08/2026S(5)2,841D$346.1575(7)3,238D
American Depositary Shares(4)09/08/2026S(5)1,517D$347.3915(8)1,721D
American Depositary Shares(4)09/08/2026S(5)1,721D$348.0126(9)0D
American Depositary Shares(4)09/08/2026M31,027A$36.931,027D
American Depositary Shares(4)09/08/2026S(5)7,492D$348.3146(10)23,535D
American Depositary Shares(4)09/08/2026S(5)10,688D$349.2834(11)12,847D
American Depositary Shares(4)09/08/2026S(5)6,569D$350.2741(12)6,278D
American Depositary Shares(4)09/08/2026S(5)6,278D$351.2542(13)0D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Share Option (Right to Buy)$2.84(14)09/08/2026M403,351 (15)11/15/2026Ordinary Shares403,351$01,210,079D
Explanation of Responses:
1. These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.
2. These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.
3. These securities are held by the spouse of the Reporting Person.
4. Each American Depositary Share represents 13 Ordinary Shares.
5. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.
6. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $344.71 to $345.66, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $345.71 to $346.70, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $346.79 to $347.78, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $347.80 to $348.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $348.07 to $348.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $348.80 to $349.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $349.81 to $350.80, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $350.82 to $351.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
14. The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.
15. These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.
Remarks:
Exhibit List - Exhibit 24.1 - Power of Attorney
/s/ Frank Collazo, as Attorney-in-Fact09/10/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

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