Palisade Bio, Inc. reported institutional holdings disclosed on a Schedule 13G. Ameriprise Financial, Inc. and its affiliate Columbia Management Investment Advisers, LLC report shared voting and dispositive power over 8,711,385 shares, representing 5.3% of the class as shown on the cover page.
The filing states AFI is the parent of CMIA and includes CMIA's reported holdings; both entities disclaim beneficial ownership. Signature and exhibit references identify a subsidiary and a joint filing agreement.
Positive
None.
Negative
None.
Insights
Large passive stake disclosure: 8,711,385 shares (5.3%) held with shared voting power.
The filing documents that Columbia Management Investment Advisers, LLC holds shared voting and dispositive authority over 8,711,385 shares, and that Ameriprise Financial, Inc. as parent includes those holdings.
These Schedule 13G filings commonly indicate institutional, non‑activist holdings; subsequent filings would show changes in percent ownership or conversion to a Schedule 13D if activist intent arises.
Key Figures
Shared voting power:8,711,385 sharesShared dispositive power:8,711,385 sharesPercent of class:5.3%
3 metrics
Shared voting power8,711,385 sharescover page; shared voting power reported
Shared dispositive power8,711,385 sharescover page; shared dispositive power reported
Percent of class5.3%cover page; percent of class shown
"Item 1. Name of issuer: Palisade Bio, Inc.; form type shown"
A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.
shared dispositive powerfinancial
"Rows indicating Shared Dispositive Power 8,711,385.00 on the cover"
disclaims beneficial ownershipregulatory
"Each of AFI and CMIA disclaims beneficial ownership of any shares reported"
What stake does Ameriprise disclose in Palisade Bio (PALI)?
Ameriprise and its affiliate report shared voting and dispositive power over 8,711,385 shares, shown as 5.3% of the class on the cover page. The filing treats AFI as parent of CMIA and includes CMIA’s reported holdings.
Does Ameriprise claim beneficial ownership of the shares?
No. The filing states that both AFI and CMIA disclaim beneficial ownership of the shares reported, while noting AFI may be deemed to beneficially own shares reported by CMIA as its parent company.
Who signed the Schedule 13G for these holdings?
The Schedule 13G is signed by Michael G. Clarke, Senior Vice President, North America Head of Operations & Investor Services, with a signature date of 05/15/2026, and contact information for Charles Chiesa is provided.
What exhibits accompany this Schedule 13G filing?
The filing lists Exhibit I identifying and classifying the subsidiary that acquired the securities and Exhibit II as the joint filing agreement between the reporting persons.
Does this Schedule 13G indicate activist intent or control changes?
No explicit activist intent or control change is stated; the filing records passive institutional disclosure via a Schedule 13G. Any change to active intent would typically be reflected by an amended filing or a Schedule 13D.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
Palisade Bio, Inc.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
696389402
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
696389402
1
Names of Reporting Persons
Ameriprise Financial, Inc.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
8,711,385.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
8,711,385.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
8,711,385.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.3 %
12
Type of Reporting Person (See Instructions)
HC
SCHEDULE 13G
CUSIP Number(s):
696389402
1
Names of Reporting Persons
Columbia Management Investment Advisers, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
MINNESOTA
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
8,711,385.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
8,711,385.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
8,711,385.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.3 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Palisade Bio, Inc.
(b)
Address of issuer's principal executive offices:
4600 South Syracuse Street, Suite 900, Denver, CO 80237
Item 2.
(a)
Name of person filing:
(a) Ameriprise Financial, Inc. ("AFI")
(b) Columbia Management Investment Advisers, LLC ("CMIA")
(b)
Address or principal business office or, if none, residence:
(a) 145 Ameriprise Financial Center, Minneapolis, MN 55474
(b) 290 Congress Street, Boston, MA 02210
(c)
Citizenship:
(a) Delaware
(b) Minnesota
(d)
Title of class of securities:
Common Stock
(e)
CUSIP Number(s):
696389402
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Incorporated by reference to Items (5)-(9) and (11) of the cover page pertaining to each reporting person.
AFI, as the parent company of CMIA, may be deemed to beneficially own the shares reported herein by CMIA. Accordingly, the shares reported herein by AFI include those shares separately reported herein by CMIA.
Each of AFI and CMIA disclaims beneficial ownership of any shares reported on this Schedule.
(b)
Percent of class:
The information required by Item 4(b) is set forth in Rows (5)-(9) and (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person.
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person.
(ii) Shared power to vote or to direct the vote:
The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person.
(iii) Sole power to dispose or to direct the disposition of:
The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person.
(iv) Shared power to dispose or to direct the disposition of:
The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for each Reporting Person hereto and is incorporated herein by reference for each Reporting Person.
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.
AFI: See Exhibit I
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Ameriprise Financial, Inc.
Signature:
/s/ Michael G. Clarke
Name/Title:
Michael G. Clarke, Senior Vice President, North America Head of Operations & Investor Services
Date:
05/15/2026
Columbia Management Investment Advisers, LLC
Signature:
/s/ Michael G. Clarke
Name/Title:
Michael G. Clarke, Senior Vice President, North America Head of Operations & Investor Services
Date:
05/15/2026
Comments accompanying signature:
Contact Information
Charles Chiesa
VP Fund Treasurer Global Operations and Investor Services
Telephone: 617-385-9593
Exhibit Information
Exhibit Index
Exhibit I Identification and Classification of the Subsidiary which Acquired the Security Being Reported on by the Parent Holding Company.
Exhibit II Joint Filing Agreement
