Precigen, Inc. reported a significant shareholder position from Patient Capital Management, LLC and its client fund. Patient Capital Management is deemed to beneficially own 36,006,800 shares of Precigen common stock, representing 10.18% of the class as of 12/31/2025.
Within this total, Patient Opportunity Trust, a Series of Advisor Managed Portfolios, is deemed to beneficially own 27,617,612 shares, or 7.8% of the common stock. The filer certifies the shares were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of Precigen.
Positive
None.
Negative
None.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 4)
PRECIGEN, INC.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
74017N105
(CUSIP Number)
12/31/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
74017N105
1
Names of Reporting Persons
Patient Capital Management, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
36,006,800.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
36,006,800.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
36,006,800.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
10.2 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP No.
74017N105
1
Names of Reporting Persons
Patient Opportunity Trust, a Series of Advisor Managed Portfolios
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
27,617,612.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
27,617,612.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
27,617,612.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
Patient Capital Management, LLC
Patient Opportunity Trust, a Series of Advisor Managed Portfolios
(b)
Address or principal business office or, if none, residence:
ONE SOUTH STREET, SUITE 2550
BALTIMORE, Maryland
21202
(c)
Citizenship:
Patient Capital Management, LLC - DELAWARE
Patient Opportunity Trust, a Series of Advisor Managed Portfolios - UNITED STATES
(d)
Title of class of securities:
Common Stock
(e)
CUSIP No.:
74017N105
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Patient Capital Management, LLC is deemed to be the beneficial owner of 36,006,800 shares of common stock. Of that total, Patient Opportunity Trust, a Series of Advisor Managed Portfolios, is deemed to be the beneficial owner of 27,617,612 shares of common stock.
(b)
Percent of class:
10.18 %
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Patient Capital Management, LLC - 36,006,800 Total
Patient Opportunity Trust, a Series of Advisor Managed Portfolios - 27,617,612 of the total
(ii) Shared power to vote or to direct the vote:
Patient Capital Management, LLC - 0
Patient Opportunity Trust, a Series of Advisor Managed Portfolios - 0
(iii) Sole power to dispose or to direct the disposition of:
Patient Capital Management, LLC - 36,006,800 Total
Patient Opportunity Trust, a Series of Advisor Managed Portfolios - 27,617,612 - of the total
(iv) Shared power to dispose or to direct the disposition of:
Patient Capital Management, LLC - 0
Patient Opportunity Trust, a Series of Advisor Managed Portfolios - 0
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Patient Capital Management, LLC
Signature:
Moira Donovan
Name/Title:
Chief Compliance Officer
Date:
02/13/2026
Patient Opportunity Trust, a Series of Advisor Managed Portfolios
What percentage of Precigen (PGEN) does Patient Capital Management report owning?
Patient Capital Management reports beneficial ownership of 10.18% of Precigen’s common stock. This equates to 36,006,800 shares as of December 31, 2025, giving the firm a sizeable institutional position in the company’s equity.
How many Precigen (PGEN) shares does Patient Opportunity Trust beneficially own?
Patient Opportunity Trust is deemed to beneficially own 27,617,612 shares of Precigen common stock. This stake represents 7.8% of the class and is included within the larger position reported by Patient Capital Management, LLC in the same ownership filing.
Is Patient Capital Management seeking to influence control of Precigen (PGEN)?
According to the certification, the securities were acquired and are held in the ordinary course of business. The filer states they were not acquired or held to change or influence control of Precigen and are not part of any such control-related transaction.
What voting and dispositive power does Patient Capital Management have over Precigen (PGEN) shares?
Patient Capital Management reports sole voting power and sole dispositive power over 36,006,800 shares of Precigen common stock. It reports no shared voting or shared dispositive power, indicating exclusive authority over how these shares are voted and disposed.
When was the ownership position in Precigen (PGEN) measured for this Schedule 13G/A?
The ownership information is reported as of December 31, 2025, identified as the date of the event requiring the filing. This date anchors the 36,006,800 shares and 10.18% beneficial ownership figures disclosed for Patient Capital Management.
Who signed the Precigen (PGEN) Schedule 13G/A for Patient Capital Management?
The filing is signed by Moira Donovan, Chief Compliance Officer, and Russell B. Simon, President. Both certify after reasonable inquiry that the information in the Schedule 13G/A is true, complete, and correct as of the reported ownership date.