Praxis (PRAX) CEO Marcio Souza gifts 23,121 shares, retains 56,495

Rhea-AI Filing Summary

Praxis Precision Medicines, Inc. Chief Executive Officer Marcio Souza reported gifting a total of 23,121 shares of Praxis common stock. The transactions are coded as bona fide gifts, meaning they were transfers without payment rather than market sales.

The filing shows 2,600 shares previously held indirectly through his spouse were gifted to the Souza 2026 Trust, reducing that indirect position to zero. An additional 20,521 directly held shares were also gifted, leaving Souza with 56,495 Praxis shares held directly after the transactions.

Insider Trade Summary

23,121 shares gifted

Mixed 2 txns

Insider Souza Marcio

Role Chief Executive Officer

Type	Security	Shares	Price	Value
Gift	Common Stock	20,521	$0.00	--
Gift	Common Stock	2,600	$0.00	--

Holdings After Transaction: Common Stock — 56,495 shares (Direct, null); Common Stock — 0 shares (Indirect, Held by spouse)

Footnotes (1)

1. [object Object]

Key Figures

Total shares gifted: 23,121 shares Direct shares gifted: 20,521 shares Indirect spouse-held shares gifted: 2,600 shares +2 more

5 metrics

Total shares gifted 23,121 shares Bona fide gifts of common stock reported on Form 4

Direct shares gifted 20,521 shares Common Stock, direct ownership, transaction code G

Indirect spouse-held shares gifted 2,600 shares Common Stock held indirectly by spouse, transaction code G

Direct holdings after transaction 56,495 shares Total Praxis common stock held directly post-gift

Gift price per share $0.0000 per share Indicates non-cash bona fide gifts of common stock

Key Terms

bona fide gift, indirect ownership, Common Stock, Form 4

4 terms

bona fide gift financial

"This transaction represents a bona fide gift of common stock to the Souza 2026 Trust."

A bona fide gift is a genuine, voluntary transfer of money, property, or benefits from one party to another made without expectation of repayment, services, or hidden conditions. Investors care because such gifts can affect company disclosures, related‑party transaction rules, tax treatment, and perceived conflicts of interest; think of it like someone giving you a present with no strings attached — but on a corporate scale, auditors and regulators need to verify it really is unconditional.

indirect ownership financial

"Common Stock transaction of 2,600.0000 shares was reported as indirect, nature of ownership held by spouse."

Common Stock financial

"Both transactions involve Common Stock with transaction code G for gifts."

Common stock represents ownership shares in a company, giving investors a stake in its success and a say in important decisions through voting rights. It is the most common type of stock traded on markets and can provide income through dividends, as well as potential for value growth. For investors, holding common stock means sharing in the company’s profits and risks.

Form 4 regulatory

"Insider transactions by the Praxis CEO are disclosed on Form 4."

Form 4 is a official document that company insiders, such as executives or major shareholders, file with regulators whenever they buy or sell company shares. It provides transparency about how those with inside knowledge are trading, helping investors see if insiders are confident in the company's prospects or may be selling for personal reasons. This information can influence investor decisions by revealing insiders' perspectives on the company's value.

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Available on EDGAR 07/08/2026 - 04:56 PM Accepted by SEC EDGAR 07/08/2026 - 04:56 PM Learn about SEC filing dates

FAQ

What insider transaction did Praxis (PRAX) CEO Marcio Souza report?

Marcio Souza reported bona fide gifts of Praxis common stock totaling 23,121 shares. The transactions were not open-market sales but transfers without payment, categorized as gifts under SEC rules, and are disclosed on a Form 4 for transparency.

How many PRAX shares did the CEO gift in this Form 4 filing?

The CEO gifted 23,121 Praxis common shares in total. This included 2,600 shares previously held indirectly through his spouse and 20,521 shares held directly, all transferred as bona fide gifts rather than sold in the market for cash proceeds.

What are Marcio Souza’s PRAX holdings after these gifted shares?

Following the gifts, Marcio Souza holds 56,495 Praxis common shares directly. The 2,600 shares that had been held indirectly through his spouse were fully gifted away, leaving no indirect holding from that position according to the reported post-transaction balances.

Were the PRAX CEO’s reported transactions market sales or gifts?

The transactions were reported as bona fide gifts, not market sales. Both entries use transaction code G for gifts, with a price per share of zero, indicating transfers without payment rather than open-market selling activity, which carries different implications for investors.

Who received the gifted PRAX shares from the CEO’s reported transactions?

The filing notes that the gifts represent transfers of common stock to the Souza 2026 Trust. One transaction involved shares held indirectly via his spouse, and the other involved shares held directly, both moved into this trust structure as disclosed in the footnote.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Souza Marcio

(Last) (First) (Middle)

C/O PRAXIS PRECISION MEDICINES, INC.

99 HIGH STREET, 30TH FLOOR

(Street)

BOSTON MASSACHUSETTS 02110

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Praxis Precision Medicines, Inc. [ PRAX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Executive Officer

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
07/08/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/08/2026		G(1)		20,521	D	$0	56,495	D
Common Stock	07/08/2026		G(1)		2,600	D	$0	0	I	Held by spouse

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. This transaction represents a bona fide gift of common stock to the Souza 2026 Trust.

Remarks:

	/s/ Alex Nemiroff, as Attorney-in-Fact	07/08/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)