Protagonist Therapeutics: BlackRock reports 15.2% stake

iShares Core S&P Small-Cap ETF is identified as having an interest exceeding 5% of PTGX's outstanding common stock.

Rhea-AI Filing Summary

Protagonist Therapeutics, Inc. (PTGX) is the issuer in BlackRock, Inc.’s Amendment No. 8 reporting beneficial ownership of 9,834,146 common shares, or 15.2% of the class.

BlackRock reports sole voting power over 9,719,796 shares and sole dispositive power over 9,834,146 shares; it reports no shared voting or dispositive power. iShares Core S&P Small-Cap ETF is identified as having an interest in more than 5% of Protagonist’s outstanding common stock.

Key Figures

Beneficial ownership: 9,834,146 shares Percent of class: 15.2% Sole voting power: 9,719,796 shares +4 more

7 metrics

Beneficial ownership 9,834,146 shares BlackRock, Inc.

Percent of class 15.2% BlackRock, Inc.’s reported beneficial ownership

Sole voting power 9,719,796 shares BlackRock, Inc.

Sole dispositive power 9,834,146 shares BlackRock, Inc.

Shared voting power 0 shares BlackRock, Inc.

Shared dispositive power 0 shares BlackRock, Inc.

Interest in outstanding common stock More than 5% iShares Core S&P Small-Cap ETF

Key Terms

beneficially owned, Sole Voting Power, Sole Dispositive Power

3 terms

beneficially owned regulatory

"Amount beneficially owned"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

Sole Voting Power regulatory

"Sole Voting Power 9,719,796"

Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.

Sole Dispositive Power regulatory

"Sole Dispositive Power 9,834,146"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many PTGX shares does BlackRock report beneficially owning?

BlackRock, Inc. reports beneficial ownership of 9,834,146 shares of Protagonist Therapeutics common stock, equal to 15.2% of the class. It reports sole voting power over 9,719,796 shares and sole dispositive power over 9,834,146 shares.

Which PTGX shareholder is identified as having an interest above 5%?

iShares Core S&P Small-Cap ETF is identified as having an interest in more than 5% of Protagonist Therapeutics’ outstanding common stock.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 10/27/2026 - 05:28 PM EDT Accepted by SEC EDGAR 10/27/2026 - 05:25 PM EDT Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 8)

Protagonist Therapeutics, Inc

(Name of Issuer)

Common Stock

(Title of Class of Securities)

74366E102

(CUSIP Number)

09/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 74366E102

1

Names of Reporting Persons

BlackRock, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 9,719,796.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 9,834,146.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

9,834,146.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

15.2 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Protagonist Therapeutics, Inc
(b)	Address of issuer's principal executive offices: 7707 GATEWAY BLVD., SUITE 140 NEWARK CA 94560-1160
Item 2.
(a)	Name of person filing: BlackRock, Inc. In accordance with SEC Release No. 34-39538 (January 12, 1998), this Schedule 13G reflects the securities beneficially owned, or deemed to be beneficially owned, by certain business units (collectively, the "Reporting Business Units") of BlackRock, Inc. and its subsidiaries and affiliates. It does not include securities, if any, beneficially owned by other business units whose beneficial ownership of securities are disaggregated from that of the Reporting Business Units in accordance with such release.
(b)	Address or principal business office or, if none, residence: BlackRock, Inc., 50 Hudson Yards New York, NY 10001
(c)	Citizenship: See Item 4 of Cover Page
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 74366E102
Item 4.	Ownership
(a)	Amount beneficially owned: 9834146
(b)	Percent of class: 15.2 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 9719796
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 9834146
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. The interest of 1 such person, iShares Core S&P Small-Cap ETF, in the common stock of Protagonist Therapeutics, Inc is more than five percent of the total outstanding common stock.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See Exhibit 99
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

BlackRock, Inc.

Signature:	Spencer Fleming
Name/Title:	Managing Director
Date:	10/27/2026

Exhibit Information

Exhibit 24: Power of Attorney Exhibit 99: Item 7