Welcome to our dedicated page for Rigel Pharmaceuticals SEC filings (Ticker: RIGL), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Rigel Pharmaceuticals' SEC filings document the regulatory record of a Delaware biotechnology company with common stock listed on Nasdaq under RIGL. Its 8-K reports frequently furnish operating results, product revenue trends, collaboration revenue and business updates tied to TAVALISSE, GAVRETO, REZLIDHIA and development programs such as R289.
The filings also cover material agreements, license and collaboration disclosures, capital-structure information for common stock, and governance matters. Proxy materials describe shareholder voting items, board matters, executive compensation and equity awards, while material-event filings record changes affecting agreements, financial reporting and corporate governance.
Rigel Pharmaceuticals reports that Eli Lilly and Company has elected to terminate their License and Collaboration Agreement covering ocadusertib (previously R552) and other RIPK1 inhibitors. Lilly’s termination is in its entirety and becomes effective June 15, 2026.
The agreement, signed on February 18, 2021, had granted Lilly an exclusive worldwide license to develop and commercialize RIPK1 inhibitors for non-CNS and CNS diseases, with potential milestone payments and royalties to Rigel. After termination, Lilly’s rights to the licensed compounds will cease, subject to transition provisions, and Rigel expects to regain full rights to these programs.
Rigel is evaluating the impact of the termination and, following this step and the earlier end of the CNS disease program effective in November 2025, does not expect to receive future milestones or royalties under the agreement.
Rigel Pharmaceuticals, Inc. is asking stockholders to vote at its virtual 2026 annual meeting on May 14, 2026. Stockholders will elect three directors to serve until the 2029 annual meeting, approve amendments to its equity incentive and employee stock purchase plans, cast an advisory vote on executive pay, and ratify Ernst & Young LLP as independent auditor for 2026.
The equity proposals would add 500,000 shares to the 2018 Equity Incentive Plan and 360,000 shares to the 2000 Employee Stock Purchase Plan. As of March 19, 2026, there were 18,480,019 shares of common stock outstanding and entitled to vote. The board unanimously recommends voting “FOR” all five proposals.
Rigel Pharmaceuticals Inc Schedule 13G/A shows The Vanguard Group reports 0 shares beneficially owned of Common Stock, representing 0% of the class as disclosed. The amendment explains an internal realignment effective January 12, 2026, after which certain Vanguard subsidiaries report holdings separately.
Rigel Pharmaceuticals reported very strong fourth quarter and full-year 2025 results driven by its hematology and oncology portfolio. Fourth quarter 2025 total revenues were $69.8 million, with net product sales of $65.4 million, up 41% from 2024, and contract revenues of $4.4 million. Net income for the quarter surged to $268.1 million, or $13.54 diluted per share, largely reflecting a $245.9 million non-cash deferred income tax benefit.
For 2025, total revenues were $294.3 million, including $232.0 million of net product sales, which grew 60% year over year, and $62.3 million of contract revenues. Full-year net income was $367.0 million, or $19.48 diluted per share. Cash, cash equivalents and short-term investments increased to $155.0 million as of December 31, 2025, from $77.3 million a year earlier.
Rigel continues to advance its pipeline, particularly the Phase 1b study of R289 in lower-risk myelodysplastic syndrome, with dose expansion enrollment ongoing and recommended Phase 2 dose selection expected in the second half of 2026. For 2026, the company anticipates total revenues of $275 to $290 million and positive net income while funding existing and new clinical programs.
Rigel Pharmaceuticals outlines a growing hematology and oncology business built around three FDA‑approved drugs and a developing pipeline. In 2025, TAVALISSE net sales reached $158.8 million, up 51.6% from 2024, while REZLIDHIA sales grew to $31.0 million and GAVRETO to $42.1 million.
The company is advancing R289 for lower‑risk myelodysplastic syndromes, with Phase 1b data showing durable transfusion independence in some heavily pretreated patients and Orphan Drug and Fast Track designations. Rigel also expands olutasidenib into new indications through collaborations with MD Anderson and CONNECT, while a settlement on TAVALISSE patents allows a generic entrant no earlier than the second quarter of 2032.
Rigel Pharmaceuticals director Walter H. Moos reported option and share transactions. On February 20, 2026, he exercised a stock option for 4,000 shares of common stock at $24.00 per share through a derivative exercise or conversion.
On the same date, he sold 4,000 shares of common stock in an open-market or private transaction at $36.36 per share. After these transactions, he directly owned 12,722 shares of Rigel Pharmaceuticals common stock. The reported numbers reflect a prior one-for-ten reverse stock split.
Rigel Pharmaceuticals executive Raymond J. Furey reported an equity compensation award in the form of Restricted Stock Units tied to the company’s common stock. The award covers 19,497 shares, reflected as an acquisition with no cash price because it is a grant, not an open-market purchase.
These Restricted Stock Units will vest quarterly over a three-year period, with the first quarterly vesting scheduled for March 31, 2026. Following this award, Furey is shown as having 51,813 shares of common stock in direct ownership, illustrating his ongoing equity alignment with the company.
Rigel Pharmaceuticals CEO and President Raul R. Rodriguez reported an equity award on common stock. He acquired a grant of 53,915 shares through a Restricted Stock Unit award at a stated price of $0.00 per share. According to the award terms, these Restricted Stock Units will vest quarterly over three years, with the first vesting date on March 31, 2026. After this grant, Rodriguez directly owns 282,017 shares of common stock.
Rojkjaer Lisa reported acquisition or exercise transactions in this Form 4 filing.
RIGEL PHARMACEUTICALS INC reported that EVP and Chief Medical Officer Lisa Rojkjaer received a grant of 18,894 shares of common stock in the form of Restricted Stock Units. These RSUs will vest quarterly over three years, starting with the first vesting on March 31, 2026. After this award, she is reported to beneficially own 34,853 shares of common stock directly.