RVMD Executive's Stock Sale Tied to RSU Tax Planning, Retains Large Position

Rhea-AI Filing Summary

Revolution Medicines (RVMD) Chief Operating Officer Margaret A. Horn reported insider trading activity on June 16, 2025. The transaction involved the sale of 3,510 shares at a weighted average price of $39.83 per share, executed through multiple trades ranging from $39.60 to $39.83.

The sale was conducted under a pre-established Rule 10b5-1 trading plan from May 31, 2023, specifically to cover tax withholding obligations related to vesting restricted stock units (RSUs). Following the transaction, Horn maintains beneficial ownership of 150,675 shares, which includes:

• 652 shares acquired through the Employee Stock Purchase Plan on May 31, 2025
• 79,776 restricted stock units (RSUs)

This transaction demonstrates a planned liquidation for tax purposes rather than a discretionary sale, executed under a compliant insider trading framework.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Horn Margaret A

(Last) (First) (Middle)

C/O REVOLUTION MEDICINES, INC.

700 SAGINAW DRIVE

(Street)

REDWOOD CITY CA 94063

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Revolution Medicines, Inc. [ RVMD ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Operating Officer

3. Date of Earliest Transaction (Month/Day/Year)
06/16/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/16/2025		S(1)		3,510	D	$39.83(2)	150,675(3)(4)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.

2. This transaction was executed in multiple trades in prices ranging from $39.6017 to $39.8291, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

3. Includes 652 shares acquired under the Issuer's Employee Stock Purchase Plan on May 31, 2025.

4. Includes 79,776 RSUs.

	/s/ Jack Anders, as Attorney-in-fact for Margaret Horn	06/18/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many shares did RVMD's COO Margaret Horn sell on June 16, 2025?

Margaret Horn sold 3,510 shares of RVMD common stock on June 16, 2025 at a weighted average price of $39.83 per share. This transaction was executed to satisfy tax withholding obligations related to vesting RSUs.

What is the total number of RVMD shares owned by Margaret Horn after the June 2025 transaction?

Following the reported transaction, Margaret Horn beneficially owned 150,675 shares of RVMD, which includes 652 shares acquired through the Employee Stock Purchase Plan on May 31, 2025 and 79,776 Restricted Stock Units (RSUs).

Was RVMD COO Margaret Horn's June 2025 stock sale part of a 10b5-1 trading plan?

Yes, the transaction was made pursuant to a Rule 10b5-1 instruction letter that was adopted on May 31, 2023. The sale was specifically designed to satisfy tax withholding obligations upon the vesting of restricted stock units (RSUs) after July 15, 2023.

What was the price range of RVMD shares sold by Margaret Horn in the June 2025 transaction?

The shares were sold in multiple trades at prices ranging from $39.6017 to $39.8291 per share, with a weighted average sale price of $39.83.

How many RVMD shares did Margaret Horn acquire through the Employee Stock Purchase Plan?

Margaret Horn acquired 652 shares through RVMD's Employee Stock Purchase Plan on May 31, 2025.