Rhythm insider plans stock sales under 10b5-1

Rhythm Pharmaceuticals insider Pamela Cramer filed a Form 144 indicating planned sales of company common stock through Morgan Stanley Smith Barney LLC.

Rhea-AI Filing Summary

Rhythm Pharmaceuticals insider Pamela Cramer filed a Form 144 indicating planned sales of company common stock through Morgan Stanley Smith Barney LLC. The filing lists 10b5-1 plan sales and includes shares issuable from stock option exercises and restricted stock units, as well as a prior sale of 3,520 shares for $411,452.80 on August 10, 2026.

Key Figures

Recent shares sold: 3,520 shares Sale value: $411,452.80 Stock option-related shares: 5,257 shares +2 more

5 metrics

Recent shares sold 3,520 shares Common shares sold on 08/10/2026 under 10b5-1 sales

Sale value $411,452.80 Proceeds from sale of 3,520 common shares on 08/10/2026

Stock option-related shares 5,257 shares Common tied to Exercise of Stock Options dated 08/11/2026

RSU-related shares 6,149 shares Common tied to Restricted Stock Units dated 07/26/2022

Broker identifier 11,406 Figure listed with Morgan Stanley Smith Barney LLC Executive Financial Services

Key Terms

10b5-1, Restricted Stock Units, Exercise of Stock Options, Form 144, +1 more

5 terms

10b5-1 regulatory

"10b5-1 Sales for PAMELA CRAMER 222 Berkeley Street"

A 10b5-1 plan is a pre-set schedule that lets company insiders buy or sell shares according to written instructions made when they do not possess material, nonpublic information. Think of it as a timed automatic payment for stock trades: it helps insiders avoid accusations of trading on secret information and gives outside investors a clearer signal about whether sales are routine or potentially informative about the company’s prospects.

Restricted Stock Units financial

"Common | 07/26/2022 | Restricted Stock Units | Issuer"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

Exercise of Stock Options financial

"Common | 08/11/2026 | Exercise of Stock Options | Issuer"

Form 144 regulatory

"144: Securities To Be Sold Common"

Form 144 is a document that investors must file with the government when they plan to sell a large number of shares of a company's stock. It helps ensure transparency so everyone knows how many shares are being sold and when, which can impact the stock's price.

Executive Financial Services financial

"Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does the Form 144 filed for RYTM disclose about planned stock sales?

The Form 144 discloses that Pamela Cramer plans sales of Rhythm Pharmaceuticals common stock under a 10b5-1 trading plan. It identifies Morgan Stanley Smith Barney LLC as broker and references shares from stock options and restricted stock units.

How many RYTM shares were sold recently under the 10b5-1 plan?

The filing shows a prior sale of 3,520 common shares on 08/10/2026 for $411,452.80. This transaction is reported in the section covering securities sold during the past three months under the 10b5-1 plan.

Which broker is handling the RYTM Form 144 sales for Pamela Cramer?

The broker handling the proposed transactions is Morgan Stanley Smith Barney LLC Executive Financial Services, located at 1 New York Plaza, 8th Floor, New York, NY 10004. The securities involved are shares of Rhythm Pharmaceuticals common stock.

What types of RYTM equity awards are referenced in the Form 144?

The Form 144 references Common stock linked to an Exercise of Stock Options dated 08/11/2026 and Restricted Stock Units dated 07/26/2022. These awards represent shares that may be sold as they become deliverable.

Is the RYTM Form 144 linked to a Rule 10b5-1 trading plan?

Yes. The remarks section specifies "10b5-1 Sales for PAMELA CRAMER", indicating that the reported and proposed transactions are structured under a Rule 10b5-1 trading plan for systematic share sales.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 08/11/2026 - 04:31 PM Accepted by SEC EDGAR 08/11/2026 - 04:30 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001873517
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	RHYTHM PHARMACEUTICALS, INC.
SEC File Number	001-38223
Address of Issuer	222 Berkeley Street, 12th Floor BOSTON MASSACHUSETTS 02116
Phone	8572644280
Name of Person for Whose Account the Securities are To Be Sold	PAMELA CRAMER
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	11406	1317164.88	68852082	08/11/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	08/11/2026	Exercise of Stock Options	Issuer			5257	08/11/2026	Cash
Common	07/26/2022	Restricted Stock Units	Issuer			6149	07/26/2022	N/A

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
10b5-1 Sales for PAMELA CRAMER 222 Berkeley Street, 12th Floor BOSTON MA 02116	Common	08/10/2026	3520	411452.80

144: Remarks and Signature

Remarks	The securities to be sold were acquired upon the vesting of restricted stock units during the period of 7/26/2022 through 7/26/2024.
Date of Notice	08/11/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	12/15/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Pamela Cramer
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)