Welcome to our dedicated page for Scynexis SEC filings (Ticker: SCYX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The SCYNEXIS, Inc. (SCYX) SEC filings page on Stock Titan provides access to the company’s official regulatory documents as filed with the U.S. Securities and Exchange Commission. These filings offer detailed information on SCYNEXIS’s antifungal drug development programs, its exclusive license agreement with GSK for ibrexafungerp and BREXAFEMME, financial condition, governance, and risk factors.
Investors can review annual reports on Form 10-K and quarterly reports on Form 10-Q for comprehensive discussions of the company’s fungerp platform, including ibrexafungerp and second-generation candidate SCY-247, as well as descriptions of clinical programs, collaboration terms, and revenue recognition from the GSK license agreement. These periodic reports also summarize research and development expenses, selling, general and administrative costs, cash balances, and other key financial metrics.
Current reports on Form 8-K capture material events such as the binding memorandum of understanding with GSK resolving the disagreement over the Phase 3 MARIO study, associated payments, and updates on the transfer of the BREXAFEMME New Drug Application. Other 8-K filings describe Nasdaq listing notices, annual meeting voting results, and similar corporate developments.
This page also surfaces proxy statements and related materials that address director elections, advisory votes on executive compensation, and auditor ratification. Together, these documents help users understand SCYNEXIS’s governance structure and shareholder decisions.
Stock Titan enhances these filings with AI-powered summaries that explain complex sections in plain language, highlight key changes from prior periods, and point out items such as license agreement terms, clinical program disclosures, and capital structure details. Users can quickly scan new 10-K, 10-Q, and 8-K filings, as well as track warrant liabilities, deferred revenue, and other line items that SCYNEXIS reports in its financial statements.
Federated Hermes, Inc. and related reporting persons filed an amended Schedule 13G/A reporting beneficial ownership of 3,533,250 shares of SCYNEXIS, INC. common stock, representing 8.42% of the class as of 12/31/2025. Federated Hermes has sole voting and dispositive power over these shares, while the Voting Shares Irrevocable Trust reports the same sole voting and dispositive power.
Individuals Thomas R. Donahue, Ann C. Donahue, and J. Christopher Donahue each report shared voting and shared dispositive power over the same 3,533,250 shares and the same 8.42% stake. The filers state the securities were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of SCYNEXIS. They also expressly disclaim beneficial ownership of securities held by the managed funds.
SCYNEXIS (SCYX) reported Q3 2025 results. License revenue was $334,000, down from $660,000 a year ago. Operating expenses fell to $8.7 million, led by lower R&D at $5.5 million and SG&A of $3.3 million. The company posted a net loss of $8.6 million, or $0.17 per share, including a $0.6 million loss from warrant fair value adjustments.
Cash, cash equivalents, and short-term investments totaled $37.9 million as of September 30, 2025. Convertible notes were repaid at maturity in March 2025, reducing current debt to zero. A $10.0 million license receivable is on the balance sheet tied to the GSK collaboration.
After quarter-end, SCYNEXIS and GSK signed a binding memorandum of understanding under which SCYNEXIS will wind down the MARIO study and receive one-time payments totaling $24.8 million. Other potential milestones and royalties under the GSK license remain unchanged. The company also disclosed a Nasdaq minimum bid price notice received on June 20, 2025, with a compliance period through December 17, 2025.
SCYNEXIS (SCYX) reported an insider transaction on a Form 4. On 10/17/2025, a company Chief Executive Officer and Director acquired 32,500 shares of common stock at $0.76 per share. Following this trade, the insider’s beneficial ownership stands at 853,098 shares, held directly.
The filing notes this total includes 4,000 shares acquired under the 2014 Employee Stock Purchase Plan on 09/05/2025.
SCYNEXIS (SCYX) entered a binding memorandum of understanding with GSK to amend their exclusive license, resolving the prior disagreement over the Phase 3 MARIO study of ibrexafungerp. SCYNEXIS will promptly wind down and terminate the MARIO study and will receive $22 million from GSK, plus an additional $2.3 million in connection with the wind-down and termination activities. SCYNEXIS will not receive additional milestone payments specifically tied to MARIO.
GSK reiterated its commitment to the broader collaboration, including commercialization of BREXAFEMME (ibrexafungerp tablets) for VVC and rVVC. SCYNEXIS continues to progress the transfer of the BREXAFEMME NDA to GSK by the end of 2025. GSK anticipates initiating FDA interactions in 2026 to discuss a U.S. relaunch for VVC and rVVC. Other potential milestones and royalties under the exclusive license remain unchanged.
Federated Hermes, Inc. and related Reporting Persons report beneficial ownership of 5,116,598 shares of Scynexis Inc. common stock, representing
SCYNEXIS, Inc. reported that the FDA lifted the clinical hold on ibrexafungerp on April 24, 2025, and dosing in the Phase 3 MARIO study resumed in May 2025, prompting the company to bill a $10.0 million development milestone to GSK in Q2 2025. The company is disputing GSK’s April 28, 2025 notice that purported to terminate the MARIO study and deny further milestone payments, including a $30.0 million milestone tied to study resumption.
Financially, SCYNEXIS recognized $1.364 million in license revenue for the quarter and reported a net loss of $6.885 million for Q2 2025 ($12.276 million year-to-date). Cash and investments totaled $46.5 million at June 30, 2025 (down from $75.1 million at year-end), the March 2019 convertible notes were repaid $14.0 million in March 2025, and the accumulated deficit was $388.8 million. The company received a Nasdaq deficiency notice on June 20, 2025 for a closing bid below $1.00 and has until December 17, 2025 to regain compliance. Ongoing securities class and derivative lawsuits remain pending.
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