Septerna shareholder proposes $14.9M share sale

Available on EDGAR 11/12/2026 - 06:00 PM EST Accepted by SEC EDGAR 11/12/2026 - 05:59 PM EST Learn about SEC filing dates

Rhea-AI Filing Summary

Septerna, Inc. (SEPN) shareholder Samsara BioCapital, L.P. filed notice of a proposed sale of 306,645 common shares, with an aggregate market value of $14,890,681.20. The notice lists November 12, 2026 as the approximate sale date and Merrill Lynch as the broker.

The shares are listed as acquired from Septerna in an IPO purchase on October 25, 2024, for cash. The notice lists 47,549,223 shares outstanding and is signed by Srini Akkaraju, MD, PhD.

Key Figures

Proposed shares for sale: 306,645 shares Aggregate market value: $14,890,681.20 Shares outstanding: 47,549,223 shares

3 metrics

Proposed shares for sale 306,645 shares Septerna common stock; approximate sale date November 12, 2026

Aggregate market value $14,890,681.20 Value listed for the proposed sale

Shares outstanding 47,549,223 shares Septerna common stock

Key Terms

Aggregate Market Value

1 terms

Aggregate Market Value financial

"Aggregate Market Value"

Aggregate market value is the combined price you would pay to buy all outstanding shares of a company or all companies in a group at current market prices — essentially the sum of each stock’s market capitalization. It matters to investors because it shows the overall size and weight of an investment or sector (like the total cost to buy every piece of a puzzle), helps compare scale across companies or markets, and influences index composition and risk exposure.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many SEPN shares does Samsara BioCapital plan to sell?

Samsara BioCapital, L.P. gave notice of a proposed sale of 306,645 common shares, with an aggregate market value of $14,890,681.20. The approximate sale date is November 12, 2026.

How did Samsara BioCapital acquire the SEPN shares it plans to sell?

The shares are listed as acquired from Septerna in an IPO purchase on October 25, 2024, with cash as the nature of payment.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001699737
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	Septerna, Inc.
SEC File Number	001-42382
Address of Issuer	250 East Grand Avenue South San Francisco CALIFORNIA 94080
Phone	6503383533
Name of Person for Whose Account the Securities are To Be Sold	Samsara BioCapital, L.P.
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Shareholder

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Merrill Lynch 555 California Street 18th Floor San Francisco CA 94104	306645	14890681.2	47549223	11/12/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	10/25/2024	IPO Purchase	Issuer			306645	10/25/2024	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks
Date of Notice	11/12/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	Srini Akkaraju, MD, PhD
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)