Septerna CEO granted 400,000 stock options

Septerna, Inc. reported a stock option grant to its Chief Executive Officer and director, Jeffrey Finer.

Rhea-AI Filing Summary

Septerna, Inc. reported a stock option grant to its Chief Executive Officer and director, Jeffrey Finer. On February 6, 2026, he was awarded a stock option to purchase 400,000 shares of Septerna common stock at an exercise price of $25.41 per share.

The option expires on February 5, 2036. According to the vesting schedule, 2/48 of the shares will vest and become exercisable on March 1, 2026, and the remaining shares will vest in 46 substantially equal monthly installments, subject to his continuous service with the company.

Insider Trade Summary

Grant/Award: 400,000 shares

Grant/Award 1 txn

Insider Finer Jeffrey

Role Chief Executive Officer

Type	Security	Shares	Price	Value
Grant/Award	Stock Option (Right to Buy)	400,000	$0.00	$0.00

Holdings After Transaction: Stock Option (Right to Buy) — 400,000 contracts (Direct)

Footnotes (1)

1. F1. 2/48th of the shares subject to such option shall vest and become exercisable on March 1, 2026 and the remaining shares subject to the option shall vest in 46 substantially equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continuous service to the Issuer on each such date.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What did Septerna (SEPN) CEO Jeffrey Finer report on this Form 4?

Jeffrey Finer reported receiving a stock option grant for 400,000 shares of Septerna common stock. The option was awarded on February 6, 2026, and reflects equity-based compensation tied to his role as Chief Executive Officer and director at the company.

What is the exercise price of Jeffrey Finer’s Septerna stock options?

The stock option granted to Jeffrey Finer carries an exercise price of $25.41 per share. This is the price he must pay to purchase each share if and when the option is exercised, subject to vesting and other standard conditions described in the filing.

How many Septerna shares are covered by Jeffrey Finer’s new option grant?

The option grant covers 400,000 shares of Septerna common stock. These shares are not owned outright at grant but may be acquired over time as the option vests and becomes exercisable, assuming Jeffrey Finer continues his service with Septerna.

When do Jeffrey Finer’s Septerna stock options start vesting and over what period?

Vesting begins on March 1, 2026, when 2/48 of the option shares become exercisable. The remaining shares vest in 46 substantially equal monthly installments on each monthly anniversary thereafter, contingent on Jeffrey Finer’s continuous service with Septerna on each vesting date.

When do Jeffrey Finer’s Septerna stock options expire?

The stock options granted to Jeffrey Finer expire on February 5, 2036. If any portion of the option is not exercised by that expiration date, those rights to purchase Septerna common shares under this grant will lapse and cease to be exercisable.

What is Jeffrey Finer’s role and relationship to Septerna (SEPN)?

Jeffrey Finer is both a director and the Chief Executive Officer of Septerna, Inc. This dual role is disclosed in the filing, and the reported stock option grant represents equity compensation associated with his leadership and board responsibilities at the company.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 02/10/2026 - 07:03 PM EST Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Finer Jeffrey

(Last) (First) (Middle)

C/O SEPTERNA, INC.

250 EAST GRAND AVENUE

(Street)

SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Septerna, Inc. [ SEPN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Executive Officer

3. Date of Earliest Transaction (Month/Day/Year)
02/06/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$25.41	02/06/2026		A		400,000		(1)	02/05/2036	Common Stock	400,000	$0	400,000	D

Explanation of Responses:

1. 2/48th of the shares subject to such option shall vest and become exercisable on March 1, 2026 and the remaining shares subject to the option shall vest in 46 substantially equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continuous service to the Issuer on each such date.

Remarks:

Exhibit 24.2 - Substitute Power of Attorney

	/s/ Mark A. Wilson, Attorney-in-Fact	02/10/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.